Clinical trials: Bowel Preparation
Colorectal Polyps
Research on the Application of AI Image Recognition-Based Smartphone Apps in Personalized Bowel Preparation
Colorectal cancer, as one of the most common malignant tumors of the digestive system, has a high incidence and mortality rate worldwide.
- Trial name
- NCT06610630
- Testing
- Assessment of Bowel Preparation Using AI-Driven Smartphone Applications
- Where
- China
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- Jianning Yao
Bowel Preparation
Safety and Tolerability Study of an Edible Colon Preparation
The purpose of this study is to learn about a new bowel preparation that uses food to clean the colon. In order to learn about this new food preparation, some people in this study will get the food preparation, and others will…
- Trial name
- NCT02402270
- Testing
- NuLYTELY® (PEG 3350), ECP-019, MoviPrep® (PEG 3350)
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- ColonaryConcepts LLC
Bowel Preparation
Different Dosing Time of Bowklean for the Bowel Preparation
The primary objective of this study is to compare the efficacy of administration routine bowel cleansing medication (Bowklean) for the Bowel Preparation at Different Times Prior Colonoscopy in the morning or in the afternoon.
- Trial name
- NCT04483037
- Testing
- Bowklean
- Where
- Taiwan
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Crohn's Disease
A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease
Background VSL#3 has been reported as an effective adjuvant therapy both in inducing and maintaining remission in pediatric patients affected by Ulcerative Colitis.
- Trial name
- NCT01632462
- Testing
- VSL#3
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federico II University
Colonic Polyps, Colorectal Neoplasms
Right Colon Enema to Improve Bowel Preparation Quality During Colonoscopy
Colonoscopy is a test that lets doctors look inside the large bowel to find and remove growths called polyps, which can develop into bowel cancer. Before the test, people take a bowel preparation to empty the bowel.
- Conditions
- Colonic Polyps, Colorectal Neoplasms, Colonoscopy, Bowel Preparation Quality
- Trial name
- RIGHT-CLEAN (NCT07813013)
- Testing
- Sodium phosphate enema, Water instillation
- Where
- 2 sites in Australia
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Westmead Hospital
Microbial Colonization, Irritable Bowel Syndrome
Probiotic Supplementation in the Dysbiosis of Bowel Preparation
Significant changes in gut microbiota was noted after the high-volume bowel preparation with PEG before colonoscopy. The dynamic changes were found to be short-term.
- Conditions
- Microbial Colonization, Irritable Bowel Syndrome, Metabolic Syndrome
- Trial name
- NCT04774042
- Testing
- Infloran probiotic, HAC probiotic
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Probiotics
Use of a Selected Mixture of Probiotic Strains for Degrading Gluten During Digestion
Gluten intake spreads worldwide, being the major food protein consumed in the Western diets (up to 20 g gluten/d). But gluten has unique and unusual features.
- Trial name
- NCT05798689
- Testing
- Probiotic administration and gluten
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Free University of Bozen-Bolzano
Colonoscopy, Bowel Cleansing
The Effect of pH Value of Water Consumed During Bowel Preparation Before Colonoscopy on Colon Cleansing
Colonoscopy is a commonly used minimally invasive method for evaluating the lower gastrointestinal tract. The quality of colonoscopy is assessed by factors such as cecal intubation rate and adenoma detection rate, both of which…
- Conditions
- Colonoscopy, Bowel Cleansing, Water Intake, pH
- Trial name
- NCT07669116
- Testing
- Colon preparation for colonoscopy
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Sinan Ömeroğlu, MD
Healthy Person, Bowel Preparation Before Colonoscopy
Comparison Between 2L Coolprep® and Combination of 1L Coolprep® and Bisacodyl as Bowel Preparation
comparison of the use of Colyte® (ascorbic acid mixed polyethylene glycol solution) in two-liter versus one-liter volume and pretreatment with bisacodyl for colonoscopy preparation.
- Trial name
- NCT01745835
- Testing
- 2L Coolprep®, 1L Coolprep® and Bisacodyl
- Where
- South Korea
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colonoscopy, Colonoscopy: Bowel Preparation
Risk Factors for Inadequate Bowel Preparation Before Colonoscopy
The primary objectives of this study are twofold: Firstly, to investigate the current status of bowel preparation protocols and their quality across hospitals at various levels in China, particularly following the release of the…
- Trial name
- NCT06878378
- Testing
- Investigation of Factors Influencing Bowel Preparation Quality
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colonoscopy Preparation
Efficacy and Safety of Bisacodyl and Lactulose as a Preparation for Colonoscopy
The purpose of the study is to evaluate the efficacy and safety of bisacodyl combined with escalating doses of lactulose to be used as a preparation for colonoscopy.
- Trial name
- NCT02123017
- Testing
- 90 grams of Crystalline Lactulose, 135 grams of Crystalline Lactulose, 180 grams of Crystalline Lactulose
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cumberland Pharmaceuticals
Polyps, Colon Preparation
Comparison Between Asymmetric And Standard Split-Dose Regimen For Bowel Preparation
We aimed to compare the efficacy for bowel cleansing of a split-dose regimen with a low morning dose of PEG solution (Asymmetric; 25% of the dose is given on the day of the procedure and 75% of the dose is given on the day…
- Trial name
- NCT03146052
- Testing
- PEG-4000 added with citrates and simethicone (PEG-CS) plus Bisacodyl
- Where
- Italy
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- ASST Rhodense
Colonoscopy, Patient Compliance
Evaluation of Information on Bowel Preparation for Morning Colonoscopy
Background: In randomized controlled trials, split-dose bowel preparation for colonoscopy has been shown to provide better bowel cleansing than day before bowel preparation.
- Trial name
- NCT03650725
- Testing
- Mandatory Split bowel preparation
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Harminder Singh
Healthy
Bowel Preparation May Lead to a Higher Feasibility of Intestinal Infection
An adequate bowel preparation is essential for a high quality of colonscopy. Nowdays, polyethyleneglyco is considered the most safe drug for bowel preparation, and is widely used around the world.
- Trial name
- NCT05277090
- Testing
- 2L of polyethyleneglycol, inulin, probiotic combination product
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yanqing Li
Diagnosis Disease
Efficacy, Safety and Tolerability of a New Bowel Cleansing Preparation (BLI800) in Adult Subjects Undergoing Colonoscopy
The purpose is to demonstrate that BLI800 is non-inferior, on overall colon cleansing, to Fortrans® (a reference colonic lavage in China) administered in adult subjects scheduled to undergo a colonoscopy for a routinely accepted…
- Trial name
- EASY (NCT03562884)
- Testing
- BLI800, Fortrans®
- Where
- 10 sites in China
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Ipsen
Colonoscopy: Bowel Preparation
Efficacy of Short Time Intervals in Split-Dose Bowel Preparation of Oral Sulfate Solution for Colonoscopy
To evaluate whether oral sulfate solution administered in a short time interval (6-8 hours) between the first and last dose of laxative is not inferior to a long time interval (10-12 hours) in bowel preparation quality.
- Trial name
- NCT06317597
- Testing
- Magnesium Sulfate，Sodium Sulfate and Potassium Sulfate Concentrate Oral Solution
- Where
- China
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Bowel Preparation
Compare Polyethylene Glycol and Sodium Picosulfate Alone or Combined
Sodium picosulfate/magnesium citrate (SPMC) is generally better tolerated than PEG, its cleansing effect remains uncertain. While most studies showed SPMC was non-inferior to PEG, some studies reported that SPMC was less…
- Trial name
- NCT03965182
- Testing
- PEG, PEG plus SPMC, SPMC
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Colonoscopy
Comparing Oral Preparation With Macrogol (Moviprep) and Natriumdihydrogenphosphatdihydrat (Phosphoral)
The purpose of this study is to determine whether Moviprep or Phosphoral is the best method of bowel preparation before colonoscopy - seen by the patients and by the endoscopist.
- Trial name
- NCT01705262
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Bowel Preparation
Patient Tolerability and Efficacy of Bowel Preparation With Split Dose Picosalax vs. Split Dose PEG
Introduction: Colonoscopy is an important tool for colon cancer screening. Proper colon cleansing is essential to ensure adequate mucosal examination.
- Trial name
- NCT02070341
- Testing
- Polyethylene Glycol, Picosalax
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Queen's University
Bowel Preparation for Colonoscopy
A Comparison of 5 Low Volume Bowel Preparations
The purpose of this investigation is to compare 3 versions of MiraLAX/Gatorade, MoviPrep and SUPREP to see which preparation cleanses the colon best and which preparation is best tolerated.
- Trial name
- NCT01719653
- Testing
- MiraLAX, Gatorade, MoviPrep
- Where
- United States
- Volunteers
- 1,079 people, healthy volunteers welcome
- Sponsor
- Gastroenterology Services, Ltd.