Clinical trials: Brain Fog
Brain Activity
Effects of USP Methylene Blue on Cognitive and fMRI Brain Activity
The purpose of the study is to evaluate whether low-dose USP methylene blue (MB) will: i) improve short-term memory retention in a delayed match-to-sample task, ii) reduce reaction time in a psychomotor vigilance test, and iii)…
- Trial name
- NCT01836094
- Testing
- Methylene Blue (USP grade, 280mg oral)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Secondary Traumatic Stress, Burnout, Professional
International Online Survey Assessing Secondary Traumatic Stress, Burnout, Compassion Satisfaction and Turnover Intentions Among Youth Care (Para)Professionals in Flanders, Wallonia, France and The Netherlands.
The goal of this observational study is to understand how work-related stress and personal characteristics affect the wellbeing of adults who work with children and young people in youth care services in Flanders, Wallonia…
- Conditions
- Secondary Traumatic Stress, Burnout, Professional, Compassion Fatigue, Compassion Satisfaction
- Trial name
- 2021_VUB_CFCSJ (NCT07384026)
- Where
- Belgium
- Volunteers
- 4,214 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Secondary Traumatic Stress
The Resilience Alliance
The Resilience Alliance is a skill-based staff development intervention for child protective staff that focuses on improving job satisfaction, resilience, optimism and social support, while decreasing attrition, stress reactivity…
- Trial name
- NCT02521571
- Testing
- Resiliance Alliance, Secondary traumatic stress training
- Where
- 4 sites in United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Mental Fatigue, Cognitive Function
Examining the Effects of One-Month Probiotic Treatment on Mental Fatigue
The aim of this study is to demonstrate the effects of 28-days supplementation with a novel probiotic formulation on mental fatigue following a cognitive load in healthy adults.
- Conditions
- Mental Fatigue, Cognitive Function, Mood
- Trial name
- NCT03611478
- Testing
- Probiotic formulation
- Where
- Australia
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Swinburne University of Technology
Fatigue; Muscle, Heart, Fasting
Effects of Fasting-Mimicking Diet on Central and Peripheral Components of Fatigue, Muscular Resistance
The aim of the study is to test a Fasting Mimicking Diet (FMD) for its efficacy on improving muscular resistance and endurance. The investigators will perform a randomized clinical trial to test the efficacy of the FMD on…
- Conditions
- Fatigue; Muscle, Heart, Fasting, Diet, Healthy, Fatigue, Mental
- Trial name
- FMD_Exercise (NCT04476615)
- Testing
- Fasting-Mimicking Diet (ProLon®)
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Red Tide, Neurologic Disorder
Investigating Health Impacts of Exposure to Harmful Algal Blooms
The goals of this project are to study the biological effects of environmental toxins (ET), in particular aquatic toxins such as brevetoxins (PbTx) and microcystin or their metabolites.
- Conditions
- Red Tide, Neurologic Disorder, Florida
- Trial name
- NCT06883227
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Roskamp Institute Inc.
Cognitive Assessment, Working Memory
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor.
- Conditions
- Cognitive Assessment, Working Memory, Executive Function (Cognition), Sustained Attention
- Trial name
- NCT07319117
- Testing
- Skoshify 'Think Tank' Formulation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Burnout, Professional, Anxiety
Storytelling Through Music to Improve Well-being Among Homeless Service Providers
Homelessness is a complex social issue and requires a dedicated workforce of helping professionals, including nurses and social workers.
- Conditions
- Burnout, Professional, Anxiety, Depression, Secondary Trauma
- Trial name
- NCT06536387
- Testing
- Storytelling Through Music
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Chronic Obstructive Pulmonary Disease (COPD)
Neuromuscular Fatigue in Chronic Obstructive Pulonary Disease
Fatigue is a prevalent symptom in Chronic Obstructive Pulmonary Disease (COPD) that limits patients in their daily living activities.
- Trial name
- NEUROTIGUE (NCT04028973)
- Testing
- Single then dual task situation, Dual then single task situation
- Where
- 2 sites in France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Cognition, Mental Fatigue
Investigation of Dietary Supplement Liquid Shot Products on Mental Energy, Cognition (Acuity),and Mood
This is a single center, randomized, double blind, placebo-controlled, crossover study to determine the acute effect of a developmental dietary supplement liquid shot product on cognitive task performance and perceived effect…
- Conditions
- Cognition, Mental Fatigue, Mood
- Trial name
- NCT06384586
- Testing
- Functional energy shot
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The Water Street Collective
Health, Subjective
Motor Imagery in Healthy Individuals
The research will be the first to examine the relationship between mental fatigue induced by motor imagery and upper extremity performance.
- Trial name
- NCT05236244
- Testing
- İntervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration in Noisy Environment
This study aims to examine whether listening to natural sounds in a noisy (traffic) environment compared to traffic noise only impacts behavioural, cognitive, affective, and physiological markers associated with attention…
- Conditions
- Cognitive Fatigue, Mental Fatigue, Heart Rate Variability, Skin Conductance
- Trial name
- EARS (NCT05009784)
- Testing
- Baseline, Fatigue Manipulation, Traffic Sound
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Mental Fatigue
Music Intervention on Golfers Under Mental Fatigue
This study aims to evaluate the effects of music intervention on golf-specific skill performance under mental fatigue. It is a randomised, controlled, double-blind design.
- Trial name
- NCT06952283
- Testing
- Inducing mental fatigue, Music intervention
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pan Xiaoyang
Mental Fatigue, Alertness
Effect of Coffeeberry on Mood and Cognitive Performance
The primary aim of this randomised, double-blind, placebo-controlled, cross-over study is to assess the short-term cognitive effects of two beverages containing 100 and 300 mg coffeeberry extract (obtained from the fruit of the…
- Conditions
- Mental Fatigue, Alertness, Mood, Cognition
- Trial name
- NCT04975802
- Testing
- Coffeeberry, Caffeine
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Mental Fatigue, Electroencephalography
The Electrophysiological Signature of the Mental Fatigue-induced Impairment in Endurance Performance
The purpose of this project is to provide further insights into the neurophysiology behind the MF-induced impairment in endurance performance.
- Trial name
- NCT04719975
- Testing
- Mental Fatigue (Stroop task), Control (Documentary)
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Work-Related Condition, Physical Stress
Wearable Robotic Upper Body Exoskeleton for Workers
The main aim of the project is to evaluate a novel upper body exoskeleton during simulated industrial work. In a first stage of the project, an extensive study involving the end-user companies will be carried out to clearly…
- Conditions
- Work-Related Condition, Physical Stress, Mental Fatigue
- Trial name
- Exo4Work (NCT03491501)
- Testing
- Ergonomic evaluation using questionnaires
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Mental Wellbeing
Comic Relief: Graphic Medicine as Care for Caregivers
Community care workers have been stretched to their capacity and exposed to ongoing trauma through their work addressing persistent health disparities in Inland Empire communities.
- Trial name
- NCT07207265
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of California, Riverside
Compassion Fatigue
Effect of a Compassion Fatigue Resiliency Program
This study aimed to conduct a short- and long-term Compassion Fatigue Resiliency Program and compare its impact on nurses' professional quality of life, perceived stress and resilience.
- Trial name
- NCT04372303
- Testing
- Compassion Fatigue Resiliency Program (CFRP)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Koc University Hospital
Alarm Fatigue, Patient Safety
Assessing the Impact of Monitor Maintenance Package Utilization
Bedside monitors are frequently used in monitoring vital signs of critically ill patients. Nurses working in healthcare facilities, especially in intensive care units, are required to manage devices with different alarm threshold…
- Trial name
- NCT06403397
- Testing
- Experimental group: CEASE Care Package and Remember Me Tool
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Istanbul Demiroglu Bilim University
Compassion Fatigue, Experiential Avoidance
Emotion Regulation Skill Program: Impact on Emotion Regulation, Experiential Avoidance & Compassion Fatigue
In this study, the effects of the skills development program for regulating emotions applied to oncology nurses on oncology nurses' emotion regulation, experiential avoidance, and comorbidity fatigue will be examined.
- Conditions
- Compassion Fatigue, Experiential Avoidance, Emotion Regulation Abilities, Emotion Regulation
- Trial name
- NCT06766682
- Testing
- The Skill Development Program for Emotion Regulation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hacettepe University