Clinical trials: Breast Abnormality
Breast Carcinoma, Prostate Cancer Surgery
High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins
These are patients in whom a benign or malignant tumor was recorded requiring surgery. During that surgery, the surgeon will cut away the tumor as part of the treatment of the disease.
- Conditions
- Breast Carcinoma, Prostate Cancer Surgery, Thyroid Cancer, Parathyroid Adenomas
- Trial name
- NCT06835426
- Testing
- Single intravenous injection of the radiotracer, Imaging resected specimen using the high-resolution PET-CT specimen imager
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Preterm Birth, Breast Milk Expression
Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development
This study is a randomized trial comparing 2 methods of human milk fortification for preterm infants in the neonatal intensive care unit (NICU).
- Conditions
- Preterm Birth, Breast Milk Expression, Nutrition Disorder, Infant, Brain Development Abnormality
- Trial name
- NCT03977259
- Testing
- Individually targeted fortification
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Brigham and Women's Hospital
Breast Cancer Female
In Vitro Detection of Tissue Abnormality
Intraoperative ex-vivo use of the ClearEdge Imaging Device in Breast Conserving Surgery to image the excised tissue surgical margins.
- Trial name
- NCT01209182
- Testing
- Testing a new device (LS BioPath TOUCH) on excised tissue
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- LS BioPath
Metastatic Breast Cancer, Circulating Tumor DNA
Clinical Application of Circulating Tumor DNA (ctDNA) in Patients With Late-stage Breast Cancer
This is a retrospective, observational, multi-center clinical study of circulating tumor DNA (ctDNA) application in late-stage breast cancers.
- Conditions
- Metastatic Breast Cancer, Circulating Tumor DNA, Gene Abnormality
- Trial name
- ACTDNA (NCT05079074)
- Testing
- ctDNA testing
- Volunteers
- 223 people
- Sponsor
- Hunan Cancer Hospital
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Haematological Abnormality
The Safety and Efficacy of Jobelyn in the Treatment of Breast Cancer Patients
To determine the effective functionality/potency of Jobelyn as an immunologic and haematologic booster in Breast cancer patients (start-off), thus improving the outlook and the quality of life of such patients generally
- Trial name
- NCT01936064
- Testing
- Jobelyn + Cyclophosphamide-Epirubicin6
- Where
- 2 sites in Nigeria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lagos State University
Genitourinary Abnormality, Breast Cancer Female
GSM (Genitourinary Syndrome Of Menopause) Management In Breast Cancer Survivors
The impact of treatment for GSM on the quality of life will be examined for postmenopausal women (defined as last menstrual period > 1 year ago or 6 months ago with FSH >40) who have been diagnosed with breast cancer.
- Conditions
- Genitourinary Abnormality, Breast Cancer Female, Vaginal Abnormality, Urinary Tract Infections
- Trial name
- GSM (NCT03185169)
- Testing
- Replens and coconut oil
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Alta Bates Summit Medical Center
Breast Abnormality Diagnosis
CONFIDENCE Registry
This registry has been designed to obtain real-life, post-market data on the use of the Imagio breast imaging system. This registry is sponsored by Seno Medical Instruments, Inc., the manufacturer of the device.
- Trial name
- CONFIDENCE (NCT05084729)
- Testing
- Imagio OA/US
- Where
- 3 sites in Netherlands
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Seno Medical Instruments Inc.
Breast Cancer
Quantitative Subharmonic Breast Imaging
This is a non-randomized trial of 450 women with a breast abnormality, who are scheduled for a breast biopsy of this abnormality. The study will be conducted at two clinical sites.
- Trial name
- NCT01490892
- Testing
- 3D HI and SHI of UCA
- Where
- 2 sites in United States
- Volunteers
- 219 people
- Sponsor
- Thomas Jefferson University
Breast Carcinoma, Microcalcification
Ultrasound Imaging Technique in Detecting Breast Microcalcifications in Patients Undergoing Biopsy for a Breast Abnormality
This clinical trial studies a new type of ultrasound technique, MicroPure, in detecting breast microcalcifications in patients undergoing biopsy for a breast abnormality.
- Trial name
- NCT03031561
- Testing
- Ultrasound, MicoPure ultrasound, Biopsy of Breast
- Volunteers
- 85 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Breast Abnormality
Circulating Tumor Cells (CTCs): A Potential Screening Test for Clinically Undetectable Breast Carcinoma
With an estimated > 2 million women with undetected breast cancer in the United States, the need for improved early detection is imperative.
- Trial name
- NCT01322750
- Where
- United States
- Volunteers
- 3,125 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Metastatic Breast Cancer, Circulating Tumor DNA
Circulating Tumor DNA (ctDNA)-Guided Late-Line Treatment in Patients With Late-Stage Breast Cancer
This is a retrospective, observational, multi-center clinical study of circulating tumor DNA (ctDNA) to guide late-line therapy in late-stage metastatic breast cancer patients.
- Conditions
- Metastatic Breast Cancer, Circulating Tumor DNA, Gene Abnormality
- Trial name
- ACTDNAGLT (NCT05427617)
- Testing
- Control group, Case group
- Volunteers
- 223 people
- Sponsor
- Hunan Cancer Hospital
Breast Neoplasms, Germline BRCA1 Gene Mutation
Prospective Study of MAstectomy With Reconstruction Including Robot Endoscopic Surgery
Robotic mastectomy and immediate reconstruction have been introduced in 2015. However, since robotic mastectomy is the latest surgical technique, there is a lack of studies prospectively comparing conventional mastectomy and…
- Conditions
- Breast Neoplasms, Germline BRCA1 Gene Mutation, Germline BRCA2 Gene Mutation, Benign Breast Disease
- Trial name
- MARRES (NCT04585074)
- Testing
- Robotic or endoscopic nipple sparing mastectomy, Conventional mastectomy (including nipple sparing mastectomy, skin sparing mastectomy)
- Where
- 18 sites in South Korea
- Volunteers
- 2,000 people
- Sponsor
- Severance Hospital
Cancer of the Breast, Anomaly of Breast
Autologous Fat Grafting of the Breast in Women With Post Lumpectomy Contour Defects
The purpose of the study is to evaluate the safety and efficacy of breast reconstruction using Autologous Fat Grafting (AFG) for women post lumpectomy that have contour defects.
- Trial name
- NCT02302196
- Testing
- Autologous Fat Grafting of the Breast, Control Arm
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Kaiser Permanente
Vaginal Atrophy, Genitourinary System; Disorder, Female
A Prospective Trial to Assess Breast Cancer Survivors and Vaginal Atrophy Treatment Outcomes
The focus of this study is to assess breast cancer survivors perspectives of Viveve® Treatment using patient reported outcome tools with a focus on symptoms associated with vulvovaginal atrophy/genitourinary syndrome of menopause…
- Conditions
- Vaginal Atrophy, Genitourinary System; Disorder, Female, Vaginal Abnormality, Sexual Dysfunction
- Trial name
- BRAVO (NCT03547089)
- Testing
- Viveve®
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- W. Grant Stevens, MD
Breast Cancer, BRCA 1 Gene Mutation
A Prospective CohorT Study of HandX - Assisted ENdoscopic MAstectomy: Feasibility and Safety (ATHENA I Study)
This study aims to learn whether a handheld robotic device, called the HandX, can help surgeons safely perform a minimally invasive nipple-sparing mastectomy.
- Conditions
- Breast Cancer, BRCA 1 Gene Mutation, BRCA 2 Gene Mutation, Hereditary Breast Carcinoma
- Trial name
- ATHENA I (NCT07292246)
- Testing
- Endoscopic nipple sparing mastectomy, HandX endoscopic instrument
- Where
- Greece
- Volunteers
- 15 people
- Sponsor
- Vasileios Kalles