Clinical trials: Breath Holding
Healthy Volunteers, Effect of CPAP on Chest Movement
Effect of CPAP on Breath Hold and Chest Movement in Normal Volunteers
CPAP will be applied to normal volunteers inorder to understand CPAP's effects on breathing and chest wall motion.
- Trial name
- CPAP_normal (NCT02545686)
- Testing
- Chest wall movement assessment without CPAP, Breath hold assessment without CPAP, Chest wall movement assessment with CPAP
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Exercise Training, Apnea
Breathing Protocol in Breath-hold Divers
The aim of this randomized controlled trial study was to assess the effects of an 4-week exercise program on the recovery capacity after a voluntary maximal apnea.
- Conditions
- Exercise Training, Apnea, Breathholding, Breathing Exercises
- Trial name
- NCT04366414
- Testing
- hook breathing removing nose-clip, usual breathing (UB)
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Breast Cancer
Hyperventilation and Oxygenation to Prolong Breath Hold in Breast Cancer Irradiation Treatment
With the HOBBIT trial, the investigators want to develop a technology that allows volunteers to hold their breath for a long time.
- Trial name
- HOBBIT (NCT04091542)
- Testing
- Optiflow/Ventilator
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Non-alcoholic Fatty Liver Disease (NAFLD), Non-alcoholic Steatohepatitis (NASH)
Simultaneous Quantification of Liver Fat Content, Fatty Acid Composition, and Fibrosis Using Spin-lock MRI for Steatohepatitis Assessment
Non-alcoholic fatty liver disease is a major health problem worldwide. It includes simple steatosis and NASH which has inflammation in the liver, with or without fibrosis.
- Trial name
- NCT05384652
- Where
- Hong Kong
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Healthy Amateur Divers
Effects of Voluntary Neck Extension on Cerebral Blood Flow, in Breath-hold Divers Ending an Apnoea of Two Minutes or More.
The aim of this study is to demonstrate the effect of the voluntary neck extension in the occurrence of an increase in the pulsatility index of the right internal carotid artery in the amateur diver, realizing an apnea of two…
- Trial name
- APNECK (NCT03210857)
- Testing
- apnea performing
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Exercise Training, Respiratory Muscle Training
Effects of High Intensity Interval Training (HIIT) vs. Inspiratory Muscle Training on the Recovery After a Maximal Apnea.
The aim of this randomized cross-over controlled study was to assess the effects of an 4-week exercise program on the recovery capacity after a voluntary maximal apnea.
- Conditions
- Exercise Training, Respiratory Muscle Training, High-Intensity Interval Training, Apnea
- Trial name
- (HIIT) (NCT04084535)
- Testing
- High intensity interval training, Inspiratory muscle training
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Healthy Volunteers
Assessment of 2 Different Techniques for Suppression of Respiratory Motion in Lung Cancer Treatment With Proton Therapy Using Magnetic Resonance Imaging (MRI)
Since 1996 proton therapy has been applied very successfully at the Paul Scherrer Institute in Switzerland to irradiate deep-seated, stationary tumors. In order to treat tumors within an organ which moves due to breathing (e.g.
- Trial name
- NCT03669341
- Testing
- Deep Inspiration Breath Hold (DIBH), High Frequency Percussive Ventilation (HFPV)
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Paul Scherrer Institut, Center for Proton Therapy
Sleep Disordered Breathing, Hypoxia
AT1R Blockade and Periodic Breathing During Sleep in Hypoxia
Sleep disordered breathing (SDB) is characterized by regular periods of no breathing (apnea) or low levels of breathing (hypopnea) and leads to repeated periods of low oxygenation, termed intermittent hypoxia that causes…
- Conditions
- Sleep Disordered Breathing, Hypoxia, Respiration; Sleep Disorder, Chemoreceptor Apnea
- Trial name
- NCT03335904
- Testing
- Hyperoxic Hypercapnic Ventilatory Response Test, Hypoxic Hypercapnic Ventilatory Response Test, Repeated Hypoxic Apneas
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lung Perfusion, Respiratory Physiology
Effects of Inspiratory vs Expiratory Breath-Hold on Lung Perfusion Measured by EIT Saline Indicator Method: A Self-Controlled Study
This study aims to compare lung perfusion distribution between inspiratory breath-hold and expiratory breath-hold phases using the saline indicator method combined with electrical impedance tomography (EIT).
- Conditions
- Lung Perfusion, Respiratory Physiology, Electrical Impedance Tomography, Ventilation-Perfusion Mismatch
- Trial name
- NCT07303972
- Testing
- Electrical Impedance Tomography Saline Indicator Procedure, Electrical Impedance Tomography Device
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Patent Foramen Ovale, Intrapulmonary Arteriovenous Anastamosis
Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension?
In summary, the investigators propose to study elite Croatian breath-hold and SCUBA divers. The investigators will quantify breath-hold hypoxia- and SCUBA diving-induced pulmonary hypertension and right heart function to…
- Trial name
- NCT03945643
- Testing
- Sildenafil
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Healthy Volunteers
Effects of Breath-Hold vs Standard Interval Training on Fitness in Mountaineers
This study investigated whether adding structured breath-holds to standard interval training improves cardiorespiratory fitness in recreational mountaineers more than interval training alone.
- Trial name
- NCT07703839
- Testing
- Voluntary Hypoventilation Training, Progressive Treadmill Interval Training
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohammadreza Rezaeipour, MD, PhD
Glaucoma, Intraocular Pressure
Intraocular Pressure During Static Apnea
This prospective observational study evaluated changes in intraocular pressure (IOP) during dry static apnea (STA) in breath-hold divers.
- Conditions
- Glaucoma, Intraocular Pressure, Apnea
- Trial name
- NCT07604428
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Olomouc
Healthy
Load and Hold: Impact of 7-Day Creatine Monohydrate Loading on Breath-Hold Cycling Performance
The present study aims to investigate the effects of creatine monohydrate supplementation on maximal breath-hold exercise performance on a bicycle ergometer in trained breath-hold divers.
- Trial name
- BREATHE-C (NCT07233707)
- Testing
- Creatine Monohydrate
- Where
- Greece
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Breast Neoplasm, Radiotherapy
HOBBIT 3: Mental Exercises and Temporal Alteration
In the HOBBIT-trial by Vakaet et al. A protocol was developed to increase breath-hold time using (voluntary) hyperventilation and oxygenation to achieve DIBH times around 3 minutes.
- Conditions
- Breast Neoplasm, Radiotherapy, Breath Holding, Mental Test
- Trial name
- HOBBIT-META (NCT06100068)
- Testing
- Mental Exercises and Temporal Alteration
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Healthy Subjects
Analysis of Breath Volatile Organic Compounds After Dyspnea Induced in the Healthy Subject.
The dyspnea is a common symptom in patients with many respiratory diseases particularly chronic obstructive airway diseases, but also cardiovascular pathologies, obesity, or also in the deconditioned healthy subjects.
- Trial name
- Volatopnee (NCT04418973)
- Testing
- VOCs analysis in exhaled air
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hopital Foch
Sport Physiology, Cognitive Performance
Cognitive Responses to Acute Breath-Hold Diving Training in Female Divers
This study aims to investigate the acute cognitive and physiological responses to breath-hold diving training in trained female divers.
- Trial name
- NCT07616804
- Testing
- Land-Based Breath-Hold Training, Water-Based Breath-Hold Training, Control Session
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Reversible Cerebral Vasoconstriction Syndrome
Endothelial Dysfunction in Reversible Cerebral Vasoconstriction Syndrome
Reversible Cerebral Vasoconstriction Syndrome (RCVS) is a syndrome described at the end of the 20th century. Generally, it has a benign course.
- Trial name
- DESS (NCT04463212)
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
MRI, MRI Image Enhancement
Optimizing Liver MRI Using Breath-Holding With and Without Oxygen
The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy…
- Trial name
- NCT07135401
- Testing
- Breath-hold conditions
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy Participant
Effect of Rib Cage and Spine Mobility on Maximum Breath-Hold Time
In this study, it was aimed to look at the effect of rib cage and spine mobility on maximum breath holding time. To determine the relationship between spine and rib cage mobility level and respiratory capacity.
- Trial name
- NCT05520216
- Testing
- Spinal mouse (idiag m360), chest circumference measurement, Maximum Breath Hold Test
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Pulmonary Disease, Chronic Obstructive
A Study to Assess the Pulmonary Distribution of Budesonide, Glycopyrronium and Formoterol Fumarate
This study is a 2 treatment period, single dose crossover, gamma scintigraphy study investigating the deposition in the lungs of a Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dose Inhaler.
- Trial name
- NCT03740373
- Testing
- BGF MDI (budesonide, glycopyrronium and formoterol fumarate) with 10 s breath hold, BGF MDI ((budesonide, glycopyrronium and formoterol fumarate) with 3 s breath hold
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AstraZeneca