Clinical trials: Breathing Mechanics
Bariatric Surgery
Comparison of Volume Controlled Ventilation and Pressure Controlled Ventilation in Laparoscopic Bariatric Surgery
The purpose of this study is to compare volume controlled-ventilation (VCV) and pressure-controlled ventilation (PCV) in terms of pulmonary gas exchange, respiratory mechanics and arterial blood gas values in patients undergoing…
- Trial name
- NCT03758937
- Testing
- volume-controlled ventilation, pressure-controlled ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Antalya Training and Research Hospital
Bronchiectasis
Respiratory Mechanics Effects of Flutter Valve in Bronchiectasis Patients
Considering that respiratory physiotherapy lack scientific evidence to support its application in the treatment of several obstructive diseases, this investigation was designed to evaluate the hypothesis that Flutter Valve can…
- Trial name
- NCT00656721
- Testing
- Flutter Valve
- Where
- 2 sites in Brazil
- Volunteers
- 8 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Asthma
Study to Evaluate the Impact of Obesity on Airway Inflammation and Mechanics in Asthmatics
In the United States there has been a dramatic increase in the number of people who are obese and in the number of people who have asthma. Both are considered serious public health concerns.
- Trial name
- ABI/BALA (NCT00615706)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Emory University
PCV-VG Versus VCV Ventilation Mode Effects on Hemodynamics
Effect of Pressure-Controlled Volume Guaranteed Versus Volume-Controlled Ventilation Modes on Hemodynamic Outcomes e.g ( SV, CO ) and Respiratory Mechanics During Laparoscopic Abdominal Cancer Surgeries With Exaggerated Trendelenberg Postion
The primary outcome is to compare the hemodynamic outcomes ( e.g SV , CO and CI ) using The ICON of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated…
- Trial name
- NCT07550738
- Testing
- electrical cardiometry ('ICON CARDIOTRONIC, OSYPKA MEDICAL') , Lung ultrasonography (LUS) for atelectasis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
One-lung Ventilation (OLV), Low-flow Anesthesia
Effects of Low-Flow Sevoflurane Anesthesia on Pulmonary Function During One-Lung Ventilation
This prospective observational study aims to evaluate the effects of low-flow sevoflurane anesthesia on respiratory mechanics, gas exchange, and postoperative pulmonary function in patients undergoing one-lung ventilation (OLV)…
- Conditions
- One-lung Ventilation (OLV), Low-flow Anesthesia, Thoracic Surgery, Respiratory Mechanics
- Trial name
- OLV-LOWSEVO (NCT07085546)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Respiratory Function Impaired
Efficacy of Osteopathic Manipulation on Breathing Mechanics in a Healthy Population: A Randomized Controlled Study
This study focused on improving breathing mechanics by using various osteopathic manipulative therapy (OMT) techniques. The investigators randomly assigned participants to a control group who received sham treatment and a…
- Trial name
- NCT04975542
- Testing
- Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Jayla Bostic
Anesthesia, Mechanical Ventilation
The Impact of Lumboscopy Versus Laparoscopy on Ventilatory Mechanics
There are several techniques for performing minimally invasive urological surgeries. Among them, laparoscopic surgery, robotic surgery, and lumboscopy are noteworthy (1).
- Conditions
- Anesthesia, Mechanical Ventilation, Respiratory Physiology
- Trial name
- NCT06776068
- Where
- 2 sites in Chile
- Volunteers
- 40 people
- Sponsor
- University of Chile
Respiratory Failure
Electrical Stimulation in Patients With Prolonged Mechanical Ventilation
Muscle atrophy and diaphragm dysfunction are common complication in patients with prolong mechanical ventilator (PMV) and is associated with increased rate of weaning failure and days of hospitalization.
- Trial name
- NCT02227810
- Testing
- electrical stimulation (high frequency), electrical stimulation (low frequency)
- Where
- Taiwan
- Volunteers
- 53 people
- Sponsor
- Chang Gung Memorial Hospital
Robotic Surgery
Lung Mechanics and Ventilation Efficiency in Robotic Surgery
Robotic surgery requires pneumoperitoneum and specific surgical positioning such as steep Trendelenburg, reverse Trendelenburg, or supine positioning.
- Trial name
- NCT07467135
- Testing
- Intraoperative Mechanical Ventilation Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Mechanical Ventilation Complication
Effect of Position and Pneumoperitoneum on Respiratory Mechanics and Transpulmonary Pressure During Laparoscopic Surgery
This study is an observational study measuring the esophageal pressure in anesthetized surgical patient undergoing changes in posture and pneumoperitoneum
- Trial name
- NCT03526003
- Testing
- Measurement of esophageal pressure
- Volunteers
- 20 people
- Sponsor
- Rambam Health Care Campus
Respiration
Lung Protective Ventilation Strategies
Obesity is becoming a common condition and bariatric metabolic surgery is one of the main options for treating morbid obesity. However, since most patients undergoing robotic bariatric surgery are class III obese, it brings new…
- Trial name
- NCT06247943
- Testing
- Lung Protective Ventilation Strategy, regular ventilation
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Tianjin Medical University General Hospital
COPD
Effect of a New Combination Bronchodilator on Exercise in GOLD Stage II Moderate COPD
Preliminary information from our laboratory indicated that even patients with milder chronic obstructive pulmonary disease (COPD) can have significant physiological derangements which become more pronounced during exercise…
- Trial name
- NCT01491802
- Testing
- LAMA/LABA, LAMA
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Queen's University
Laparoscopic Surgery, Positive End-Expiratory Pressure
Recruitment Maneuvers and PEEP-guided Electrical Impedance Tomography for Abdominal Laparoscopic Surgery Patients
Abdominal laparoscopy is widely utilized due to its benefits, including minimal invasiveness, improved cosmetic outcomes, and shorter hospital stays.
- Conditions
- Laparoscopic Surgery, Positive End-Expiratory Pressure, Electrical Impedance Tomography
- Trial name
- PEEP-EIT (NCT06850844)
- Testing
- electrical impedance tomography, Conventional Ventilation
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- Nguyen Dang Thu
Deep Sedation
Comparison of Oxygenation Methods in Sedation
Abstract Backgrounds and objectives: Dental treatments, especially in children who can not be cooperated, may require deep sedation due to intense anxiety and fear.
- Trial name
- NCT03893877
- Testing
- nasal cannula, nasal mask
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Bariatric Surgery, Obesity
Acute Effect of EPAP and Noninvasive Ventilation on Pulmonary Function and Lung Regional Ventilation on Bariatric Surgery
Obesity is a non-communicable chronic disease of multifactorial, involving biological, historical, ecological, economic, social, cultural and political.
- Conditions
- Bariatric Surgery, Obesity, Physical Therapy Modalities
- Trial name
- NCT02577744
- Testing
- Noninvasive Ventilation, Expiratory Positive Air Pressure
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Lung Infection, Mechanical Ventilation
Ventilator Hyperinflation With Increase of Inspiratory Time
The investigators hypothesis is that the adjustment of the inspiratory time may optimize the distribution of ventilation and increase tidal volume, producing potential therapeutic effects on the displacement of secretions and…
- Trial name
- NCT03630510
- Testing
- Ventilator hyperinflation
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Brazilian Institute of Higher Education of Censa
Laparoscopic Cholecystectomy
Respiratory Mechanics and Metabolic Changes During Low Pressure Laparoscopic Cholecystectomy
The investigators aim to investigate the differences between deep continuous muscle relaxation and moderate blockade during low-pressure (8 mmHg) laparoscopic cholecystectomy in respect to metabolic changes and respiratory…
- Trial name
- NCT02469831
- Testing
- Rocuronium
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
COPD, One Lung Ventilation
Effects of Dexmedetomidine on Respiratory Mechanics and Oxygenation During One Lung Ventilation With Chronic Obstructive Lung Disease
COPD is often associated with the airflow limitation and the pulmonary hyperinflation. During the one-lung ventilation (OLV), COPD patients' physiologic dead space increases and hypercapnia may develop.
- Trial name
- NCT02185430
- Testing
- saline infusion, dexmedetomidine infusion
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Mucus Retention, Mechanical Ventilation Complication
Efficacity and Safety of Mechanical Insufflation-exsufflation on ICU
Critically ill and intubated patients on mechanical ventilation (IMV) often present retention of respiratory secretions, increasing the risk of respiratory infections and associated morbidity.
- Conditions
- Mucus Retention, Mechanical Ventilation Complication, Mucus; Plug, Tracheobronchial
- Trial name
- NCT03316079
- Testing
- Chest physiotherapy techniques, Mechanical insufflation-exsufflation
- Where
- 3 sites in France
- Volunteers
- 26 people
- Sponsor
- University Hospital, Bordeaux
COPD
Complexity of the Airflow in COPD
Recently, there has been a growing interest in the study of nonlinear dynamics as a methodology for complementary analysis to characterize the respiratory pattern. These methods are well established in studies of heart rate.
- Trial name
- NCT01888705
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University