Clinical trials: Breathing Mechanics
Chronic Obstructive Pulmonary Disease Mild, Chronic Obstructive Pulmonary Disease Moderate
Effect Of Ketamine Infusion In Patients With COPD Applied One Lung Ventilation
Chronic obstructive pulmonary disease (COPD) patients often undergo thoracic surgery due to lung cancer and emphysematous changes.
- Conditions
- Chronic Obstructive Pulmonary Disease Mild, Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe, Lungcancer
- Trial name
- NCT02962999
- Testing
- Ketamine, Saline
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Healthy
Effect of Head and Neck Positioning on Lung Sliding in Healthy Volunteers
The goal of this clinical study is to learn how different head-of-bed positions affect lung movement during breathing in healthy adults.
- Trial name
- NCT07351201
- Testing
- Head-of-Bed Elevation
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
PCV-VG Versus VCV Ventilation Mode Effects on Hemodynamics
Effect of Pressure-Controlled Volume Guaranteed Versus Volume-Controlled Ventilation Modes on Hemodynamic Outcomes e.g ( SV, CO ) and Respiratory Mechanics During Laparoscopic Abdominal Cancer Surgeries With Exaggerated Trendelenberg Postion
The primary outcome is to compare the hemodynamic outcomes ( e.g SV , CO and CI ) using The ICON of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated…
- Trial name
- NCT07550738
- Testing
- electrical cardiometry ('ICON CARDIOTRONIC, OSYPKA MEDICAL') , Lung ultrasonography (LUS) for atelectasis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Weaning Failure, Central Respiratory Depression
Exploration of Mechanisms for Weaning Failure
This study is a prospective physiologic study. The primary study population will be adult invasive tracheal intubated patients with COPD, and investigators will collect relevant demographic data, vital signs, and baseline…
- Conditions
- Weaning Failure, Central Respiratory Depression, Diaphragm Injury, Phrenic Nerve Disorder
- Trial name
- NCT06424314
- Testing
- Monitoring of respiratory mechanics parameters
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Surgery
Esophageal Balloon Measurements to Better Characterize Thoraco-abdominal Interrelationship Mechanics.
Esophageal pressure measurements in surgical patients requiring mechanical ventilation during abdominal laparoscopic or robotic surgeries requiring intra-abdominal insufflation.
- Trial name
- NCT03624491
- Testing
- Esophageal pressure measurement guided ventilation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity, Pulmonary Atelectasis
Effects of PEEP on Heart and Lungs in Obese Subjects
Aim of this study is to better understand pathophysiology of the alteration of respiratory mechanics and cardiovascular function in obese volunteer subjects.
- Conditions
- Obesity, Pulmonary Atelectasis, Obesity Hypoventilation Syndrome, Magnetic Resonance Imaging
- Trial name
- NCT02523352
- Testing
- Non-Invasive Ventilation, Esophageal catheter positioning
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Bronchoconstriction, Inhaled Salbutamol
Salbutamol, Pharmacogenetics and Breathing Mechanics
Athletes using asthma medications called β2-agonists win a disproportionately high number of medals at Olympic Games. Due to a large variety in the genes that affect how individuals respond to β2-agonists, the investigators will…
- Conditions
- Bronchoconstriction, Inhaled Salbutamol, Cycling Performance
- Trial name
- NCT01903785
- Testing
- Salbutamol
- Where
- Canada
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Exercise
Effects of Pilates on Respiratory Mechanics
The aim of this study was to evaluate the influence of a fitness program from the application of Pilates on lung function, thoracoabdominal mobility and respiratory muscle strength in women.
- Trial name
- NCT01841385
- Testing
- Pilates method
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Asthma
Study to Evaluate the Impact of Obesity on Airway Inflammation and Mechanics in Asthmatics
In the United States there has been a dramatic increase in the number of people who are obese and in the number of people who have asthma. Both are considered serious public health concerns.
- Trial name
- ABI/BALA (NCT00615706)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Emory University
Deep Sedation
Comparison of Oxygenation Methods in Sedation
Abstract Backgrounds and objectives: Dental treatments, especially in children who can not be cooperated, may require deep sedation due to intense anxiety and fear.
- Trial name
- NCT03893877
- Testing
- nasal cannula, nasal mask
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
COVID-19
The Prognostic Factors of COVID-19 ARDS Patients and Their Long-term Follow-up of Pulmonary Function Test
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging infectious disease with high transmissibility. Around 20-25% of infected individuals develop severe COVID-19 disease requiring hospitalization and…
- Trial name
- NCT05490914
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
COPD
Complexity of the Airflow in COPD
Recently, there has been a growing interest in the study of nonlinear dynamics as a methodology for complementary analysis to characterize the respiratory pattern. These methods are well established in studies of heart rate.
- Trial name
- NCT01888705
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
COPD, One Lung Ventilation
Effects of Dexmedetomidine on Respiratory Mechanics and Oxygenation During One Lung Ventilation With Chronic Obstructive Lung Disease
COPD is often associated with the airflow limitation and the pulmonary hyperinflation. During the one-lung ventilation (OLV), COPD patients' physiologic dead space increases and hypercapnia may develop.
- Trial name
- NCT02185430
- Testing
- saline infusion, dexmedetomidine infusion
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Respiratory Muscles, Breathing Exercises
Respiratory Muscles and Inspiratory Muscle Training
The effects of inspiratory muscle training (IMT) remain controversial. Many studies have examined the effect IMT has on exercise performance, but any changes to the body that come from IMT have yet to be looked at.
- Trial name
- IMT (NCT02243527)
- Testing
- Inspiratory Muscle Training
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Respiratory Function Impaired
Efficacy of Osteopathic Manipulation on Breathing Mechanics in a Healthy Population: A Randomized Controlled Study
This study focused on improving breathing mechanics by using various osteopathic manipulative therapy (OMT) techniques. The investigators randomly assigned participants to a control group who received sham treatment and a…
- Trial name
- NCT04975542
- Testing
- Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Jayla Bostic
Neuroregulation of Breathing
Effects of Abnormal Respiratory Mechanics and Assisted Mechanical Ventilation on Neuro-regulation of Respiration
Due to recent technological improvements, it is now possible to record the electrical activity of the diaphragm (Eadi), a direct expression of the central nervous system respiratory center activity.
- Trial name
- RegAIN (NCT01818219)
- Testing
- Records of EADI derived parameters
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Robotic Surgery
Lung Mechanics and Ventilation Efficiency in Robotic Surgery
Robotic surgery requires pneumoperitoneum and specific surgical positioning such as steep Trendelenburg, reverse Trendelenburg, or supine positioning.
- Trial name
- NCT07467135
- Testing
- Intraoperative Mechanical Ventilation Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Acute Lung Injury, ARDS
The Specific Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients
The investigators aim to study the specific elastance in ALI/ARDS patients during invasive mechanical ventilation.
- Trial name
- NCT00143468
- Testing
- mechanical ventilation
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Patients at Risk of Acute Respiratory Failure
Early Detection of Acute Respiratory Failure Using an Intelligent Respiratory Monitoring System
Introduction: The monitoring of respiratory patterns is crucial in the management of respiratory diseases, but in many cases, it still relies on subjective and visual assessment.
- Trial name
- NCT07164586
- Testing
- Respiratory Pattern Monitoring, Diaphragmatic Excursion, Respiratory muscle electrical activity
- Where
- 3 sites in Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pernambuco
Rheumatoid Arthritis
Analysis of Respiratory Mechanics in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology characterized by peripheral polyarthritis, symmetric, which leads to joint destruction and deformity.
- Trial name
- NCT01641705
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Pedro Ernesto