Clinical trials: Breathing Mechanics
Abdominoplasty, Diaphragm
Gastroesophageal Reflux and Respiratory Function in Patients Undergoing Abdominoplasty
The objective of this observational study is to compare parameters of diaphragmatic mechanics, respiratory muscle function, and thoracoabdominal kinematics among women with gastroesophageal reflux disease (GERD) and a history of…
- Conditions
- Abdominoplasty, Diaphragm, Respiratory Mechanics, Gastroesophageal Reflux Disease
- Trial name
- NCT07868562
- Testing
- Assessment of anthropometric and sociodemographic data and clinical history, Assessment of Symptoms, Quality of Life, and Physical Activity, Spirometric assessment
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Mechanical Ventilation, Clinical Competence
Using Real-Time Lung Visuals to Reduce Mental Strain and Improve Diagnosis Speed
The goal of this clinical simulation study is to learn if a "Digital Twin" graphical lung display reduce the mental workload of clinicians.
- Conditions
- Mechanical Ventilation, Clinical Competence, Education Curriculum, Self Concept
- Trial name
- VERDICT (NCT07511712)
- Testing
- Real-time Graphical Lung Function Visualization (Digital Twin), Standard Ventilator Waveform Monitoring
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
COPD
Complexity of the Airflow in COPD
Recently, there has been a growing interest in the study of nonlinear dynamics as a methodology for complementary analysis to characterize the respiratory pattern. These methods are well established in studies of heart rate.
- Trial name
- NCT01888705
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Respiratory Distress, Lung Injury
Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP
This study is designed to evaluate the effect of heated humidified high flow nasal cannula (HHHFNC) as compared to noninvasive nasal continuous positive airway pressure (NCPAP) on lung function as a measure of lung injury in…
- Trial name
- NCT01939067
- Testing
- Heated Humidified High Flow Nasal Cannula, Nasal Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Chronic Obstructive Pulmonary Disease Mild, Chronic Obstructive Pulmonary Disease Moderate
Effect Of Ketamine Infusion In Patients With COPD Applied One Lung Ventilation
Chronic obstructive pulmonary disease (COPD) patients often undergo thoracic surgery due to lung cancer and emphysematous changes.
- Conditions
- Chronic Obstructive Pulmonary Disease Mild, Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe, Lungcancer
- Trial name
- NCT02962999
- Testing
- Ketamine, Saline
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Healthy
Effect of Head and Neck Positioning on Lung Sliding in Healthy Volunteers
The goal of this clinical study is to learn how different head-of-bed positions affect lung movement during breathing in healthy adults.
- Trial name
- NCT07351201
- Testing
- Head-of-Bed Elevation
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Bronchiectasis Adult
Bronchodilators on the Exercise Capacity of Bronchiectasis Patients
The bronchodilators (BD) have been widely used in bronchiectasis (BCE) therapeutic and have been shown to be effective in improving exercise capacity in patients with chronic obstructive pulmonary disease and asthma.
- Trial name
- NCT05183841
- Testing
- Bronchodilator (Ipratropium and Fenoterol)
- Where
- 3 sites in Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Asthma
Study to Evaluate the Impact of Obesity on Airway Inflammation and Mechanics in Asthmatics
In the United States there has been a dramatic increase in the number of people who are obese and in the number of people who have asthma. Both are considered serious public health concerns.
- Trial name
- ABI/BALA (NCT00615706)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Emory University
Acute Lung Injury, ARDS
The Specific Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients
The investigators aim to study the specific elastance in ALI/ARDS patients during invasive mechanical ventilation.
- Trial name
- NCT00143468
- Testing
- mechanical ventilation
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Laparoscopic Surgery, Pneumoperitoneum
Role of Individualized PEEP Vs Fixed PEEP in Mechanical Ventilation During Laparoscopic Surgeries
To compare the effects of Individualized positive end-expiratory pressure with recruitment maneuver on respiratory parameters and oxygenation in mechanical ventilation during laparoscopic surgeries with the fixed positive…
- Conditions
- Laparoscopic Surgery, Pneumoperitoneum, Positive End Expiratory Pressure (PEEP)
- Trial name
- NCT06929078
- Testing
- Protective lung ventilation methods with different positive end-expiratory pressure during Laparoscopic Surgeries
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Noor-Ul-Ain
Bariatric Surgery
Effect of Intraoperative Salbutamol Administration on Mechanical Power and Respiratory Mechanics in Obese Patients Undergoing Laparoscopic Bariatric Surgery
The primary objective of this study is to evaluate the effect of intraoperative salbutamol administration on mechanical power in obese patients undergoing laparoscopic bariatric surgery under general anesthesia.
- Trial name
- Bariatric (NCT07378605)
- Testing
- Salbutamol (Ventolin®), Normal Saline (0.9% Sodium Chloride)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Exercise
Effects of Pilates on Respiratory Mechanics
The aim of this study was to evaluate the influence of a fitness program from the application of Pilates on lung function, thoracoabdominal mobility and respiratory muscle strength in women.
- Trial name
- NCT01841385
- Testing
- Pilates method
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Chronic Obstructive Pulmonary Disease
Pathophysiological Mechanisms of Dyspnea and Activity-limitation in Mild Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a growing cause of death, disability and health care costs in Canada. Nevertheless, COPD remains largely under-diagnosed and under-treated, particularly in its early stages.
- Trial name
- NCT00975403
- Testing
- Dead space breathing, Room air breathing
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Neuroregulation of Breathing
Effects of Abnormal Respiratory Mechanics and Assisted Mechanical Ventilation on Neuro-regulation of Respiration
Due to recent technological improvements, it is now possible to record the electrical activity of the diaphragm (Eadi), a direct expression of the central nervous system respiratory center activity.
- Trial name
- RegAIN (NCT01818219)
- Testing
- Records of EADI derived parameters
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Respiration
Substantial Equivalence Study for Kai Medical Non-Contact Respiratory Rate Monitors for Use With Neonates
The purpose of this study is to test the accuracy of two devices (the Kai Spot (v 2.1) and the Kai Continuous (v 1.0) that can measure breathing patters (how fast you breath) without wires and without touching the body.
- Trial name
- NCT01324817
- Testing
- Kai Spot (v 2.1), Kai Continuous (v 1.0)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kai Medical, Inc.
Rheumatoid Arthritis
Analysis of Respiratory Mechanics in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology characterized by peripheral polyarthritis, symmetric, which leads to joint destruction and deformity.
- Trial name
- NCT01641705
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Pedro Ernesto
Spinal Stenosis, Lumbosacral Region
Stability Comparison of TIVA and Sevoflurane in Prone Spinal Surgery(TIVA:Total Intravenous Anesthesia)
Key Points: 1. Objective: o To compare the effects of Total Intravenous Anesthesia (TIVA) and sevoflurane anesthesia on respiratory mechanics, hemodynamic parameters, and neuromonitoring during prone position spinal surgeries. 2.
- Trial name
- TIVA (NCT06558695)
- Testing
- Sevoflurane, TIVA
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Respiratory Muscles, Breathing Exercises
Respiratory Muscles and Inspiratory Muscle Training
The effects of inspiratory muscle training (IMT) remain controversial. Many studies have examined the effect IMT has on exercise performance, but any changes to the body that come from IMT have yet to be looked at.
- Trial name
- IMT (NCT02243527)
- Testing
- Inspiratory Muscle Training
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Prostate Cancer, Anesthesia
Low-flow Versus Minimal-flow Sevoflurane Anesthesia During Robot-assisted Laparoscopic Radical Prostatectomy
Study Synopsis This protocol is formatted for ClinicalTrials.gov-style registration and manuscript-facing documentation. It is based on the uploaded Turkish ethics protocol and keeps the original core design: comparison of…
- Conditions
- Prostate Cancer, Anesthesia, Respiratory Mechanics
- Trial name
- NCT07475533
- Testing
- Common Anesthetic Management
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
PCV-VG Versus VCV Ventilation Mode Effects on Hemodynamics
Effect of Pressure-Controlled Volume Guaranteed Versus Volume-Controlled Ventilation Modes on Hemodynamic Outcomes e.g ( SV, CO ) and Respiratory Mechanics During Laparoscopic Abdominal Cancer Surgeries With Exaggerated Trendelenberg Postion
The primary outcome is to compare the hemodynamic outcomes ( e.g SV , CO and CI ) using The ICON of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated…
- Trial name
- NCT07550738
- Testing
- electrical cardiometry ('ICON CARDIOTRONIC, OSYPKA MEDICAL') , Lung ultrasonography (LUS) for atelectasis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University