Clinical trials: Burn Patients
Burn Injury
Exercise in Burn Survivors: Cooling Modalities
This project will identify the efficacy of cooling modalities aimed to attenuate excessive elevations in skin and internal body temperatures during physical activity in well-healed burn survivors.
- Trial name
- NCT04512976
- Testing
- Control (no cooling modalities), Water Spray Only, Fan Only
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Burn Injury
Skin Wetting in Burn Survivors
This project will identify the efficacy of whole body skin wetting aimed to attenuate excessive elevations in internal body temperatures during physical activity in well-healed burn survivors.
- Trial name
- NCT06529757
- Testing
- Whole body cooling, Non-cooling
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Glucose Metabolism Disorders, Hunger
Food Orders on Blood Glucose and Fuel Use at Rest
Consuming a carbohydrate-rich food as the final food in a meal, as compared to the first food in a meal, has been shown to reduce blood glucose levels after eating in both diabetes patients and in healthy controls.
- Conditions
- Glucose Metabolism Disorders, Hunger, Fat Burn
- Trial name
- NCT06763562
- Testing
- Carbohydrate-first meal, Carbohydrate-last meal
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Burn, Health Education
Gamified Approach To Burn Education
The goal of this clinical trial is to evaluate whether different educational strategies can improve knowledge acquisition regarding burn prevention and first aid among students enrolled in a community-based preparatory course.
- Conditions
- Burn, Health Education, Accident Prevention, First Aid
- Trial name
- NCT07404501
- Testing
- Serious Digital Game for Burn Prevention and First Aid, Face-to-Face Educational Lecture on Burn Prevention and First Aid
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Children, Acute Pain
Phoenixin and Pain in Pediatric Burn Patients
This prospective, controlled, observational study aims to investigate the relationship between phoenixin (PNX) levels and pain in pediatric burn patients.
- Conditions
- Children, Acute Pain, Burn Pain, Burn Degree Second
- Trial name
- NCT07858409
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Thermal Burn, Amitriptyline
Pilot Studies Blocking Injury-Induced MVP Release in Skin Using Topical Amitriptyline
The purpose of this study is to determine the amount of substances contained in skin known as microvesicle particles (MVP). Studies suggest these MVP are involved in many conditions such as after the thermal burn injury.
- Trial name
- NCT07716722
- Testing
- Amitriptyline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wright State University
Hyperthermia, Burn Injury
IEEM- Work:Rest Cycles in Burn Survivors- Humidity
The purpose of this project is to identify the effects of a severe burn injuries in humans on core temperature responses during work:rest cycles while in a heated environment.
- Trial name
- NCT06966336
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Burns, First Aid
Effects of the Mobile Application Developed for Families After the Earthquake on First Aid Knowledge and Burn Prevention
The aim of this project was to determine the effect of the burn prevention and first aid mobile application developed for families living in tent cities and container houses after the earthquake on the burn prevention and first…
- Conditions
- Burns, First Aid, Mobile Application, Earthquake
- Trial name
- NCT06155149
- Testing
- Mobile application, Family Information Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Burn Pit Exposure
Tele-Exercise for MERP
During Operations Desert Shield and Desert Storm, Veterans in combat were exposed to a variety of airborne hazards, including oil well fire smoke, emissions from burn pits, and other substances associated with negative health…
- Trial name
- TEMPO (NCT07018466)
- Testing
- Tele-exercise, Standard of Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Microvesicle Particles, Thermal Burn
Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle Release
The purpose of this study is to determine the amount of substances contained in skin known as microvesicle particles (MVP). The hypothesis to be tested in this study is that treatment with a single dose of 75mg of amitriptyline…
- Trial name
- NCT07640061
- Testing
- Amitriptyline
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wright State University
Stress, Well-being
Leading Well-being and the Psychosocial Working Environment - A Cluster-randomized Waitlist Controlled Trial
The design comprises a cluster, randomized waitlist controlled design. The goal of the study is to prevent stress and burnout in middle managers and employees in a hospital setting.
- Conditions
- Stress, Well-being, Burn Out
- Trial name
- Matterhorn (NCT05623371)
- Testing
- Training leaders in leading well-being and the psychosocial working environment, The offer of a webinar and written material
- Where
- Denmark
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Burn Injury
Cardiovascular Responses in Burn Survivors During Exercise
This project will identify the efficacy of cooling modalities aimed to attenuate excessive elevations in skin and internal body temperatures, and associated indices of cardiovascular stress, during physical activity in…
- Trial name
- NCT06709781
- Testing
- Control (no cooling modalities), Water Spray
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Posttraumatic Stress Disorder, Burns
Early Intervention to Prevent Development of PTSD in Burn Survivors and Their Caregivers
The purpose of this clinical trial is to adapt and test a brief patient-caregiver early intervention designed to reduce posttraumatic stress symptoms in hospitalized burn patients and their caregivers.
- Conditions
- Posttraumatic Stress Disorder, Burns, Traumatic Injury, Acute Stress Disorder
- Trial name
- NCT07656545
- Testing
- Promotion of Emotional Disclosure for Burns (PoED-B), minimally Enhanced Usual Care control (mEUC)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Burn Out, Nurses
Mitigating Burnout in Nursing and Associated Healthcare Staff
Workplace stress for healthcare workers is at an all-time high and the COVID-19 Pandemic magnified and amplified the impact of stress and burnout on health care workers, especially for frontline staff such as nurses.
- Trial name
- NCT07018609
- Testing
- Zen Den Experience, Music Therapy Experience
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Chronic Wounds, Burns
THERAVEX Tissue Care Spray Plus for the Management of Cutaneous Wounds, Burns, and Chronic Ulcers
Pilot observational clinical evaluation assessing the safety and potential effectiveness of THERAVEX Tissue Care Spray Plus as an adjunctive topical therapy for the management of cutaneous wounds, burns, traumatic lesions…
- Conditions
- Chronic Wounds, Burns, Pressure Ulcer, Traumatic Wounds
- Trial name
- NCT07617961
- Testing
- THERAVEX TISSUE CARE SPRAY PLUS
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL
Quality of Work Life, Burn-out
Effect of in Situ Simulation on Quality of Work Life and Multiprofessional Team Effectiveness in the Intensive Care Unit
The lack of specific, personalized training for intensive care workers can lead to a deterioration in quality of life at work, and can result in burnout, absenteeism or wanting to leave the service.
- Conditions
- Quality of Work Life, Burn-out, Simulation
- Trial name
- EFFIQUASS (NCT06944821)
- Testing
- In-situ simulation, Role-playing using a simulation scenario, Questionnaires
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Burn Out
Effect of Physician Peer Coaching on Burnout in Hospital-Based Physicians: A Pilot Randomized Clinical Trial
The prevalence of burnout symptoms among physicians is high, especially for acute care physicians. Physician burn out is a long-term stress reaction marked by emotional exhaustion, depersonalization, and a lack of sense of…
- Trial name
- NCT05251675
- Testing
- Physician Led Professional Coaching, Delayed Physician Led Professional Coaching
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Burn Injury, Body Temperature Regulation
The Effect of Simulated Burn Injury on Post Exercise Recovery in Hot Environments
Burn survivors have difficulty thermoregulating due to reduced skin blood flow and sweating responses at the grafted sites. It has been previously shown that this impaired heat dissipation results in burn survivors experiencing…
- Conditions
- Burn Injury, Body Temperature Regulation, Cardiovascular Physiology
- Trial name
- HSR (NCT07050264)
- Testing
- Simulated burn injury via application of absorbent and impermeable material over 60% of the body
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
PFAS, Environmental Exposures
Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study
The goal of this study is to test the efficacy and feasibility of Colesevelam administration (50% of the recommended dose) to reduce serum PFAS concentration in the Veteran population who have serum PFAS levels that exceed the…
- Conditions
- PFAS, Environmental Exposures, Occupational Exposure to Chemicals, Military Exposure
- Trial name
- PAVERS (NCT07592858)
- Testing
- Colesevelam
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Burn Out
Preventing Burnout Among Caregivers Through Physical Activity
The purpose of this study is to evaluate the impact of an adaptive physical activity programme to prevent the risk of burnout at the end of the programme (10 weeks after the start of the intervention).
- Trial name
- PACA (NCT06815484)
- Testing
- Intervention group with physical activity programme, Recommendations of the World Health Organisation
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche