Clinical trials: CAD/CAM, active
Class II Malocclusion, Mandibular Deficiency
Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II
Objective: to evaluate the dentoskeletal effects of CAD/CAM 3D-Printed fixed twin block versus MARA appliances in the management of skeletal class II due to Mandibular Deficiency in Preadolescence Class II malocclusion is…
- Trial name
- NCT07340242
- Testing
- MARA appliance, fixed twin block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Speech, Denture, Partial, Removable
Intelligibility and Acoustic Speech Performance of CAD/CAM Milled Titanium Partial Dentures
Partial dentures play a crucial role in restoring oral function and aesthetics for patients with missing teeth. Traditionally, these prostheses have been fabricated using materials such as acrylic resin or cobalt-chromium alloys.
- Conditions
- Speech, Denture, Partial, Removable, CAD-CAM
- Trial name
- NCT06589570
- Testing
- Removable Partial Denture
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Badr University
Endodontically Treated Teeth
Milled vs 3D-Printed Partial-Coverage Restorations in Endodontically Treated Molars
The goal of this clinical trial is to compare the clinical performance of Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM)-milled and 3D-printed composite resin partial-coverage restorations in endodontically…
- Trial name
- NCT07643311
- Testing
- Milled Composite Resin Onlay/Overlay Restoration, 3D-Printed Composite Resin Onlay/Overlay Restoration
- Where
- Chile
- Volunteers
- 142 people
- Sponsor
- Hospital San Jose
Badly Decayed Molars
Clinical Evaluation of 3D Printed Versus CAD/CAM Milled Onlays
The digital workflow in dentistry has proven in the past decades to be a time-efficient, multifunctional, effortless, and accessible approach.
- Trial name
- NCT06774560
- Testing
- CAD/Cam milled onlays, 3D printed onlays
- Volunteers
- 50 people
- Sponsor
- Cairo University
Deep Caries Lesion of Pemanent Teeth
Adjustment Period for Partial Crowns
The aim of this study is to compare the occlusal accuracy of CAD/CAM milled and 3D printed crowns guided by an occlusal device, starting from the same digital CAD design.
- Trial name
- Adjustment per (NCT07051590)
- Testing
- cad cam, 3D printer
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ceren Sire
Dental Caries, Dental Restoration, Permanent
Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM
The aim of this clinical study is to compare CAD-CAM and 3D restorations in individuals with two hard tissue losses or restorations in their mouths.
- Conditions
- Dental Caries, Dental Restoration, Permanent, Tooth Diseases
- Trial name
- NCT07031856
- Testing
- 3D printer partial crown, Treatment as usual
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Endodontically Treated Teeth, Nonvital Teeth
Clinical Comparison of Lithium Disilicate and 3D-Printed Resin Endocrowns
This randomized controlled clinical trial aims to compare the clinical performance of CAD/CAM lithium disilicate (IPS e.max CAD) and 3D-printed resin (BEGO VarseoSmile TriniQ) endocrown restorations in endodontically treated…
- Conditions
- Endodontically Treated Teeth, Nonvital Teeth, Restoration of Endodontically Treated Posterior Teeth
- Trial name
- NCT07874906
- Testing
- IPS e.max CAD Lithium Disilicate Endocrown, BEGO VarseoSmile TriniQ Resin Endocrown
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medipol University
Edentulous Maxilla
Clinical Study Investigating the Efficiency and Complications Related to Two Different Procedures Used for the Preparation of Dentures Applied in Patients With Edentulous
The principal aim of the study is to evaluate the prosthetic complications with CAD-CAM fabricated provisional prostheses and denture conversion prostheses after 3 months of function.
- Trial name
- NCT05332977
- Testing
- CAD-CAM fabricated provisional prosthesis, DC (denture conversion) provisional prosthesis
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Edentulism Complete, Edentulism
PRINTOW: Occlusal Wear of Denture Teeth in Digitally Fabricated Complete Dentures
This randomized controlled trial evaluates the occlusal wear of denture teeth fabricated using three digital workflows: 3D-printed denture teeth, CAD/CAM-milled double cross-linked denture teeth, and prefabricated denture teeth.
- Trial name
- Printow (NCT07585162)
- Testing
- CAD/CAM-Milled Denture Base with Milled Denture Teeth, CAD/CAM-Milled Denture Base with Prefabricated Denture Teeth, 3D-printed denture base and teeth
- Volunteers
- 45 people
- Sponsor
- Najla Chebib
Molar Incisor Hypomineralization
Computer-aided Design/Computer-aided Manufacturing for Mild to Moderate Molar Incisor Hypomineralization Treatment
Molar Incisor Hypomineralization (MIH) is a disease causing a structural defect in the enamel of permanent teeth. The treatment of these teeth consists of the removal of the affected part of the tooth and its reconstitution.
- Trial name
- MIhCFAO (NCT04922177)
- Testing
- Indirect ceramic restoration, Direct restoration
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Toulouse
Mouthguard Use Orofacial Injuries Prevention 3D Printed Mouthguard Traditional Custom-made Mouthguard Occlusal Thickness Changes
Comparative Assessment of Thickness Changes in 3D-Printed vs. Custom-Made Mouth Guards for Children in Contact Sports
This study aims to compare changes in the thickness of traditional and 3D-printed custom mouth guards in pediatric athletes who participate in contact sports.
- Trial name
- NCT07000435
- Testing
- 3D printed custom-made mouth guards, Traditional custom-made mouth guards
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Stability, Periodontal Health
Clinical Effectiveness of Cobalt Chromium CAD-CAM Designed Customized Lingual Retainer
This study aims to evaluate the clinical effectiveness of CAD/CAM 3D printed Chrome Cobalt fixed retainer in maintaining mandibular anterior teeth stability.
- Conditions
- Tooth Stability, Periodontal Health, Patient Satisfaction
- Trial name
- NCT06837168
- Testing
- Stainless steel fixed retainer, 3D printed CAD/CAM Chrome cobalt fixed lingual retainers
- Where
- Iraq
- Volunteers
- 42 people
- Sponsor
- University of Baghdad
Endodontically Treated Molar, Dental Restoration, Permanent
3D Printed Ceramic-Filled Photopolymer Resin Vs. CAD/CAM Resin Composite Overlays for Restoration of Extensively Damaged Endodontically Treated Posterior Teeth. An 18-month Follow-up
II. Introduction: 6. Background and rationale: Restoring badly mutilated teeth was and has always been a challenge in restorative dentistry.
- Trial name
- 3D CAD/CAM RCT (NCT07378982)
- Testing
- 3D printed overlay restorations, CAD/CAM restorations
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Edentulous Alveolar Ridge
Monolithic Zirconia With CAD/CAM Titanium Abutments: A 5-year Prospective Case Series Study
Background There is a growing interest in restoring function in the posterior maxilla and mandible with dental implants. Next to this, these implants must be restored with crowns which are subject to minimal complications.
- Trial name
- NCT06110611
- Testing
- Astra Tech Osseospeed EV® dental implant
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- University Medical Center Groningen
Denture, CAD/CAM
Effect of Certain Denture Disinfectants on Surface Topography, Microhardness and Dimensional Stability of CAD/CAM Milled Polymethyl Methacrylate and Polyether Ether Ketone Denture Base Materials
This study aims to evaluate and compare the influence of different denture cleansing methods using 1% sodium hypochlorite solution, 0.2% chlorhexidine solution and effervescent alkaline peroxide tablet solution -according to…
- Conditions
- Denture, CAD/CAM, Stability, PEEK
- Trial name
- NCT07672847
- Testing
- M0 group, M1 group : PMMA+ Sodium hypochlorite, M2 group: PMMA+ Chlorhexidine
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Menoufia University
Palatal Expansion Technique
Evaluation of Hard and Soft Tissue Change During Maxillary Expansion Using a Computer-aided Design / Computer-aided Manufacturing Appliance.
Hard tissue changes during the transversal expansion of the maxilla using a CAD/CAM expansion appliance. Soft tissue changes during the transversal expansion of the maxilla using a CAD/CAM expansion appliance.
- Trial name
- NCT06246656
- Testing
- Maxillary Expansion
- Where
- Austria
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Peri-implant Soft Tissue Healing
Soft Tissue Response and IL-1β Levels Around CAD/CAM-Milled vs 3D-Printed PMMA Healing Abutments
This study looked at how the gums and tissues around dental implants heal when using two different types of temporary healing caps made of PMMA (a common dental material).
- Trial name
- NCT07287722
- Testing
- CAD/CAM-Milled PMMA Healing Abutment, 3D-Printed PMMA Healing Abutment
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ali Hassan Eid Toto
Maxillary Sinus, Allograft
Maxillary Sinus Augmentation Using CAD/CAM Allogenic Bone Blocks Versus Particulate Allogenic Grafts
28 patients will be included in this study with atrophic posterior maxillary ridge due to sinus pneumatization who will randomly assigned to two groups Group I: sinus lifting using CAD/CAM allogenic block through lateral window…
- Trial name
- NCT07604155
- Testing
- sinus lifting using CAD/CAM allogenic block, sinus lifting using particulate allogenic graft
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Tanta University
Tooth, Nonvital, Dental Restoration
Additive vs Subtractive Manufacturing for Endocrown Fabrication: A 24-Month RCT
This randomized controlled trial (RCT) compares the 24-month clinical performance of endocrown restorations fabricated by two digital manufacturing pathways: additive manufacturing using 3D-printed ceramic-filled photopolymer…
- Conditions
- Tooth, Nonvital, Dental Restoration, Endodontically Treated Teeth
- Trial name
- ENDO-3D (NCT07633574)
- Testing
- CAD/CAM Milled HC Hard Block Endocrown, 3D-Printed VarseoSmile TriniQ Endocrown
- Volunteers
- 60 people
- Sponsor
- Cairo University
Maxillary Diseases
Patient Satisfaction & Abutment Teeth Health in Maxillectomy Patients
randomized controlled trial in maxillectomy patients with two types of obturators with different manufacturing techniques
- Trial name
- NCT06934551
- Testing
- obturator
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University