Clinical trials: CAD
Coronary Artery Disease, Endothelial NO-synthase
Regulation and Signaling of Red Blood Cell (RBC) Endothelial Nitric Oxide Synthase (eNOS) in Patients With Stable and Unstable Coronary Artery Disease
The aim of this study is measurement of expression and activity of RBC eNOS in different clinical cohorts of patients with coronary artery disease and acute coronary syndrome and to investigate the importance of the NO-stimulated…
- Trial name
- NCT02265016
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Vertical Ridge Deficiency, Horizontal Ridge Deficiency
Vertical and Horizontal Mandibular Ridge Augmentation Techniques
The purpose of this study is to compare alveolar ridge augmentation outcomes of two types of membranes for vertical and horizontal mandibular ridge augmentation: Customized CAD/CAM Titanium Mesh versus Reinforced Perforated PTFE…
- Trial name
- NCT06636084
- Testing
- Guided bone regeneration (GBR)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Coronary Artery Disease
The ATLANTA First in Man Study of the Catania Stent
To evaluate the short-term and mid-term safety and efficacy of the Catania coronary stent for the treatment of up to two de novo lesions in native coronary arteries.
- Trial name
- ATLANTA (NCT00799032)
- Testing
- PCI
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- CeloNova BioSciences, Inc.
Coronary Artery Disease
Safety and Efficacy of CAG and PCI Via Distal Transradial Access in Patients With Small Vessels
Randomized controlled trial of adaptive design for the safety and efficacy of coronary angiography and percutaneous coronary intervention via distal transradial access using a 6-French Glidesheath Slender in patients with small…
- Trial name
- DISTAL-SV (NCT07410364)
- Testing
- Performing coronary angiography and percutaneous coronary intervention via the distal transradial access in patients with small vessels (DRA < 2.0 mm) using a 6-Fr Glidesheath Slender sheath., Performing coronary interventional procedures via the distal radial artery in patients with small vessels ( DRA diameter < 2.0 mm ) using a 6-Fr Conventional sheath.
- Where
- 2 sites in China
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- Cai gaojun, MD
Coronary Artery Disease
F-18 Rhodamine 6G PET Imaging for Myocardial Blood Flow
Use of novel radio-pharmaceutical Rhodamine 6G to determine myocardial blood flow
- Trial name
- NCT04528758
- Testing
- Rhodamine 6G
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Impact of Health Information Exchange on Patient Care, (Focus on Diabetes, Asthma, Hypertension, CHF, COPD, CAD,
Evaluation of a Regional Electronic Health Information Exchange's Clinical Health Record
The Shared Health CHR™ (Clinical Health Record) offers point-of-care clinical reporting and decision support based primarily on patient claims data aggregated across various health care settings, and is one example of the types…
- Conditions
- Impact of Health Information Exchange on Patient Care, (Focus on Diabetes, Asthma, Hypertension, CHF, COPD, CAD,, Gastroenteritis, Seizures, and Bacterial Pneumonia)
- Trial name
- NCT00978744
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Denture, Complete
Conventional Versus Digital 3D Printed Complete Removable Dentures
The study is a crossover, randomised, controlled clinical trial that will compare and evaluate patients' satisfaction and oral microbiota proliferation in two groups.
- Trial name
- CRD (NCT05845099)
- Testing
- Polymethyl Methacrylate-Based Complete Removable Dentures., Photopolymerized Methacrylate- Based Complete Removable Dentures.
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Implants, Single-Tooth, Dental Implant-Abutment Design
Effect of Abutment Configuration on Peri-implant Soft and Hard Tissue in the Esthetic Zone - Randomized Clinical Trial
The aims of our study are to investigate in patients with immediate implantation replacing a single tooth in the maxillary anterior (#FDI 15-25) region the effect of (a) custom vs cylindrical stock healing abutments, then (b)…
- Trial name
- NCT06407271
- Testing
- CAD/CAM custom ZrO2 healing abutment, Cylindrical ZrO2 healing abutment
- Where
- Hungary
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Incentive Spirometry, Oxygen Saturation
The Effects Incentive Spirometry Use in Coronary Artery Bypass Surgery
Background: Incentive spirometry is used in addition to care, especially in reducing pulmonary complications after surgery. Complications in the cardiovascular and pulmonary systems can basically be determined by blood values and…
- Trial name
- NCT05192785
- Testing
- Incentive Spirometry Group
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Coronary Heart Disease, Myocardial Infarction
Prospective Coronary Heart Disease Cohort
To evaluate the biomarkers for the prognosis of coronary heart disease, patients with coronary heart disease will be recruited and followed up for at least 2 years.
- Trial name
- NCT05699629
- Where
- China
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Shandong First Medical University
Diabetes Mellitus, Hypertension
Rajavithi Health Promotion Project (Population Base Cohort)
Metabolic Syndrome (hypertension, diabetes mellitus, obesity, cerebrovascular-cardiovascular disease) In Community Survey was performed in central Bangkok.
- Conditions
- Diabetes Mellitus, Hypertension, Dyslipidemia, Obesity
- Trial name
- NCT00368095
- Testing
- Intensive Education for Metabolic Syndrome Patients
- Where
- Thailand
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Breast Neoplasms, Breast Diseases
Construction of a Benchmark for Breast Ultrasound AI Interpretation and Performance Evaluation of Multimodal AI Models
This single-center, retrospective, observational study aims to construct a standardized benchmark evaluation system for intelligent breast ultrasound image interpretation and to systematically assess the diagnostic performance of…
- Conditions
- Breast Neoplasms, Breast Diseases, Ultrasonography
- Trial name
- BUST-AI Bench (NCT07500428)
- Testing
- Multimodal AI Model Diagnostic Evaluation
- Where
- China
- Volunteers
- 1,380 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Prevention Harmful Effects, Health Maintenance
Lifewise Preventive Video Education in Primary Care
It is widely accepted that prevention is far more impactful than curative medicine and must be included in primary care. In a previous pilot study, we evaluated passive video preventive lifestyle education in the emergency…
- Conditions
- Prevention Harmful Effects, Health Maintenance, Preventive Health Care, Dietary Habits
- Trial name
- NCT06730737
- Testing
- Video preventive education
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Trinity Health-Livonia
Drug Resistance
Laboratory Aspirin Resistance in Diabetics and Non-Diabetics
Despite treatment with aspirin a large number of patients suffer a myocardial infarction. It has been speculated that these patients might be "resistant" to aspirin, and studies have indicated that this phenomenon is related to a…
- Trial name
- NCT00563875
- Testing
- acetylsalicylic acid
- Where
- Denmark
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Edentulous Alveolar Ridge
Soft and Hard Tissue Changes Around Implants
Our long-term goal is to generate evidence for the creation of successful implant restorations and ideal supporting tissues in adequate health by utilizing patient-tailored implant protocols such as the use of customized…
- Trial name
- NCT05769673
- Testing
- Placement of dental implant, Placement of stock healing abutment, Placement of customized CAD/CAM healing abutment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Partial Edentulism Class 3
Compare CAD/CAM Metallic RPD to Conventional Metallic RPD in Terms of Oral Health Related Quality of Life
Patients will be randomised to receive CAD/CAM metallic removable partial denture (RPD) followed by Conventional metallic RPD (Group A), or the opposite sequence (Group B), with a 3-month wear duration for each denture and…
- Trial name
- NCT06567262
- Testing
- CAD/CAM metallic removable partial denture, Conventional metallic removable partial denture
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cardiovascular Diseases, Coronary Disease
Lifetime Risk for Cardiovascular Disease Among Non-White Ethnic Groups
Cardiovascular disease (CVD) is one of the leading causes of death in the United States. Currently, there is little information about the lifetime risk of CVD among non-white ethnic groups.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Failure, Congestive, Atrial Fibrillation
- Trial name
- NCT00377702
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Risk Factors, Coronary Disease
CPR Training: Video Self-Instruction Kit or Video-Only
Prompt delivery of cardiopulmonary resuscitation (CPR) is a crucial determinant of survival for many victims of sudden cardiac arrest (SCA), yet bystander CPR is provided in less than one third of witnessed SCA events.
- Conditions
- Cardiovascular Risk Factors, Coronary Disease, Cardiac Arrest
- Trial name
- NCT01514656
- Testing
- CPR Training using the Family and Friends CPR Anytime Video Self Instruction, Implementation of a Hospital-based CPR Training Model, Follow-up prompting to encourage skill retention
- Where
- 3 sites in United States
- Volunteers
- 1,870 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Restoration of Primary Molars With CAD/CAM Crowns
Primary Molars Restoration Using Different Pediatric Crowns.
study aims to compare hybrid ceramic CAD/CAM and prefabricated zirconia ans stainless steel crowns restoring primary molars through In-vivo evaluation of the clinical outcomes in terms of; crown retention, stain resistance and…
- Trial name
- NCT04144062
- Testing
- CAD/CAM crowns
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nehal Salman
Coronary Atherosclerosis
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease
The purpose of this study is: 1. To examine the association between stable and unstable coronary artery disease (CAD) with markers of DNA damage and repair, 2.
- Trial name
- DECODE (NCT02335086)
- Where
- 2 sites in United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Surrey