Clinical trials: CAD-CAM
Prosthesis (Internal) Complications
Comparison of Prosthetic Complications and Framework Misfit Among Different Cobalt-Chromium Framework Fabrication Techniques
This randomized clinical study aimed to compare prosthetic complications and framework misfit associated with three different fabrication techniques of cobalt-chromium frameworks-conventional casting, CAD/CAM milling, and…
- Trial name
- NCT07489027
- Testing
- Implant supported prosthesis
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Denture, Complete, Jaw, Edentulous
Milled Versus Printed CAD/CAM Complete Dentures
A crossover clinical trial investigates two novel CAD/CAM techniques for complete removable dental prostheses for edentulous patients, milling and rapid prototyping (3D-printing) in a clinical setting of an undergraduate student…
- Trial name
- MILLPRINT (NCT04873219)
- Testing
- manufacturing a complete dental prosthesis
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Tooth Loss, Dental Implant
A 36-month Analysis of the Clinical Performance of Individualized CAD/CAM-produced Dental Implants: a Cohort Study
The goal of this prospective cohort study is to evaluate the clinical performance of a new generation of customized CAD/CAM pre-fabricated root-analog dental implants over a 36-month period.
- Trial name
- NCT06576284
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Crown
A Comparative Clinical Study to Evaluate Crowns Designed by Artificial Intelligence Versus Crowns Designed Traditional Design Software
This clinical research aims to Evaluate Crowns Designed by Artificial Intelligence Versus Crowns Designed by Traditional Design Software The research will be conducted on a sample of patients with an indication for crowning of…
- Trial name
- AI (NCT07099261)
- Testing
- Crowns
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Latakia University
Speech, Denture, Partial, Removable
Intelligibility and Acoustic Speech Performance of CAD/CAM Milled Titanium Partial Dentures
Partial dentures play a crucial role in restoring oral function and aesthetics for patients with missing teeth. Traditionally, these prostheses have been fabricated using materials such as acrylic resin or cobalt-chromium alloys.
- Conditions
- Speech, Denture, Partial, Removable, CAD-CAM
- Trial name
- NCT06589570
- Testing
- Removable Partial Denture
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Badr University
Missing Teeth, Dentures
Comparison Between Conventional and CAD/CAM Complete Dentures Designed Based on Neutral Zone Concept
A within-subject cross-over study is done on eight completely edentulous patients to compare two different complete removable dentures.
- Trial name
- NCT05990088
- Testing
- Heat Cured Conventional Polymethylmethacrylate Complete Removable Dentures based on neutral zone concept, CAD/CAM Milled Methacrylate Complete Removable Dentures based on neutral zone concept.
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Restoration of Primary Molars With CAD/CAM Crowns
Primary Molars Restoration Using Different Pediatric Crowns.
study aims to compare hybrid ceramic CAD/CAM and prefabricated zirconia ans stainless steel crowns restoring primary molars through In-vivo evaluation of the clinical outcomes in terms of; crown retention, stain resistance and…
- Trial name
- NCT04144062
- Testing
- CAD/CAM crowns
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nehal Salman
Partial Edentulism Class 3
Compare CAD/CAM Metallic RPD to Conventional Metallic RPD in Terms of Oral Health Related Quality of Life
Patients will be randomised to receive CAD/CAM metallic removable partial denture (RPD) followed by Conventional metallic RPD (Group A), or the opposite sequence (Group B), with a 3-month wear duration for each denture and…
- Trial name
- NCT06567262
- Testing
- CAD/CAM metallic removable partial denture, Conventional metallic removable partial denture
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Cairo University
CAD/CAM, Patient Specific Implant
Tooth and Bone-borne Cutting/Repositioning Guide and Patient-specific Implant(PSI)
Dentofacial deformity refers to a group of disorders characterized by malocclusion and facial asymmetry resulting from developmental abnormalities of the maxilla and mandible, which cause morphological and positional anomalies of…
- Conditions
- CAD/CAM, Patient Specific Implant, Orthognathic Surgery, Surgery-first
- Trial name
- PSI (NCT07634276)
- Testing
- bimaxillary surgery(Lefort I and SSRO)
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College
Dental Prosthesis
Titanium Versus Soft Metal CAD/CAM Frameworks for All-on-4 Implant Supported Prosthesis
This study is aimed to compare between titanium framework and soft metal framework used for mandibular All-on-4 implant supported prosthesis.
- Trial name
- NCT06114966
- Testing
- CADCAM
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tooth Wear
Minimally Invasive Treatment of Worn Dentition With Innovative CAD-CAM Composites
This study evaluates the effectiveness of a minimally invasive treatment, consisting of partial polymer-infiltrated-ceramic-network (PICN) restorations, used in case of rehabilitation of advanced and generalized dental wear over…
- Trial name
- NCT02828696
- Testing
- "No prep" treatment of worn dentition with CAD-CAM composite
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Liege
Mouthguard Use, Orofacial Injuries Prevention
Impact of 3D-Printed and Custom Mouthguards on Speech and Oral Functions in Children Practicing Contact Sports
This study aims to compare the effects of traditional and 3D-printed custom-made mouthguards on speech and oral functions in pediatric cases who practice contact sports by evaluating the comfort, fit, and performance of both…
- Conditions
- Mouthguard Use, Orofacial Injuries Prevention, 3D Printed Mouthguard, Traditional Custom-made Mouthguard
- Trial name
- Mouthguards (NCT06972823)
- Testing
- 3D printed custom-made mouthguards, Traditional custom-made mouthguards
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Implant, Computer-assisted
Accuracy of Static Computer-assisted Implant Surgery in Distal Free-end Scenarios
Technological advances have influenced the approach to implant treatment. One of the fields presently experiencing rapid development is static computer-assisted guided surgery (sCAIS), which allows transfer of the virtual implant…
- Trial name
- NCT06404385
- Testing
- Static computer-assisted guided surgery with analogic guide, Static computer-assisted guided surgery with CAD-CAM surgical guide
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Middle Ear Disease
Improved Otologic Implants on Demand Intraoperatively With 3D CAD/CAM Autografts
Prospectively analyze the use of 3D subtraction CAD/CAM in the operating room environment. Study participants, requiring middle ear surgery and ossicular reconstruction, will be implanted with one of two middle ear implants.
- Trial name
- NCT03297736
- Testing
- 3D CAD/CAM autograft prosthesis, Control device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Nitinetics LLC
Root Canal Infection, Tooth Defect
Clinical Trial of Modified Endocrown and Personalized Post-core and Crown for Large-area Tooth Defects After Root Canal Treatment
This study intends to adopt a multicenter, randomized controlled, single-blind, non-inferiority clinical trial design. 246 premolars that meet the inclusion criteria after complete root canal treatment will be selected from the…
- Conditions
- Root Canal Infection, Tooth Defect, Post and Core Technique
- Trial name
- NCT07206108
- Testing
- modified endocrown
- Where
- China
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Crowns (MeSH Unique ID: D003442), Single Tooth, Dental Porcelain (MeSH Unique ID: D003776)
Monolithic CAD/CAM Single Tooth Ceramic Crowns
With the development of Computer Aided Design and Computer Aided manufacturing (CAD / CAM) systems, all ceramic restorations have been used with high success rates during the past 30 years in order to eliminate the disadvantages…
- Trial name
- NCT04474093
- Testing
- Zirconium-reinforced glass ceramics(ZRGC),Lithium disilicate glass ceramics(LGC), Resin infiltrated glass ceramics(RIGC)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Occlusion, Occlusal Splints
Clinical Performance of CAD/CAM Occlusal Splints Fabricated With or Without a Wax Bite Registration in Healthy Adults
Occlusal splints are commonly used to manage sleep bruxism, temporomandibular disorders, and tooth wear. Traditionally, a wax bite registration is used during the fabrication of CAD/CAM occlusal splints to determine the vertical…
- Conditions
- Occlusion, Occlusal Splints, Occlusal Analysis, Comfort
- Trial name
- Splint (NCT07720453)
- Testing
- Occlusal splint fabricated using a virtual increase of the vertical dimension, Occlusal splint fabricated using a conventional wax bite registration
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Edentulous Alveolar Ridge
Soft and Hard Tissue Changes Around Implants
Our long-term goal is to generate evidence for the creation of successful implant restorations and ideal supporting tissues in adequate health by utilizing patient-tailored implant protocols such as the use of customized…
- Trial name
- NCT05769673
- Testing
- Placement of dental implant, Placement of stock healing abutment, Placement of customized CAD/CAM healing abutment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Edentulous Mouth
Retention of Computer Aided Design and Computer Aided Manufacturing Titanium Versus Co/Cr Single Dentures.
Steps in short: Undergoing the conventional steps of maxillary single denture construction till the step of framework construction that will be designed and constructed using CAD/CAM after optical scanning of the master cast ( 2…
- Trial name
- NCT03675594
- Testing
- CAD/CAM titanium denture base, CAD/CAM cobalt/chromium denture bases
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Skeletal Abnormalities
Condylar Segment Repositioning Using CAD/CAM Generated Wafer After BSSO in Skeletal Mandibular Deformity
Maintaining the condylar position after bilateral sagittal split ramus osteotomy (BSSO) is one of the most important aspects in terms of condylar function ,.An altered condylar position can cause internal derangement of the…
- Trial name
- NCT03983265
- Testing
- Bilateral Sagittal Split Osteotomy
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University