Clinical trials: CAD-CAM
Mandibular Injuries
Accuracy and Outcome of Computer-assisted Surgery for Bony Micro-vascular Reconstruction in the Head and Neck Region
Background: Functional and aesthetic reconstruction of mandibular defects due to tumour invasion, osteoradio- or chemonecrosis or trauma are challenging.
- Trial name
- NCT03054012
- Volunteers
- 30 people
- Sponsor
- AZ Sint-Jan AV
Mouthguard Use Orofacial Injuries Prevention 3D Printed Mouthguard Traditional Custom-made Mouthguard Occlusal Thickness Changes
Comparative Assessment of Thickness Changes in 3D-Printed vs. Custom-Made Mouth Guards for Children in Contact Sports
This study aims to compare changes in the thickness of traditional and 3D-printed custom mouth guards in pediatric athletes who participate in contact sports.
- Trial name
- NCT07000435
- Testing
- 3D printed custom-made mouth guards, Traditional custom-made mouth guards
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Prosthesis and Implant Dentistry
Passive Fit of Implant-Supported Complete-Arch Prostheses Using Digital Workflows
The goal of this clinical trial is to evaluate and compare three digital workflows for the fabrication of definitive implant-supported full-arch prostheses in adult patients requiring fixed implant rehabilitation.
- Trial name
- MFS03-Pdental (NCT07315620)
- Testing
- CBCT-STL Alignment Workflow, Splint-Guided Alignment Workflow, Automated AI-Assisted CBCT-STL Alignment Workflow
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Pediatric Dentistry, Premature Loss of Primary Molars
Evaluation of Polyetheretherketone and Monolithic Zirconia Versus Conventional Metal Band and Loop Space Maintainers in Children: A Randomized Split-Mouth Clinical Trial
Compare two tooth-colored CAD/CAM band and loop space maintainers, PEEK and monolithic zirconia (BruxZir), each against a conventional stainless-steel band and loop in children with premature loss of mandibular primary first…
- Conditions
- Pediatric Dentistry, Premature Loss of Primary Molars, Space Maintainer
- Trial name
- NCT06558968
- Testing
- PEEK band and loop space maintainer, BruxZir band and loop space maintainer, conventional stainless-steel band and loop space maintainer
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Periimplant Bone Loss, Marginal Periimplant Bone Level
Changes on the Interproximal Bone Level on Direct Prostheses or With Intermediate Abutments
Study Title: Changes on the Interproximal marginal bone level after CAD-CAM designed bridges directly placed on bone-level implants, or with intermediate abutments. A Randomized Clinical Trial.
- Conditions
- Periimplant Bone Loss, Marginal Periimplant Bone Level, Periimplantitis
- Trial name
- NCT04369170
- Testing
- prosthesis connected directly to the implants, Intermediate abutment
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- University of Santiago de Compostela
Fractured Tooth, Decayed Tooth
Celtra Duo Computer Assisted Design/Computer Assisted Machining (CAD/CAM) Dental Crown Study
This investigation will be a clinical trial to study the performance of a newly developed high strength ceramic material for crowns. The ceramic has been approved by the FDA for patient treatment.
- Conditions
- Fractured Tooth, Decayed Tooth, Unsatisfactory Restoration of Tooth
- Trial name
- NCT03036579
- Testing
- Celtra Duo
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Michigan
Missing Tooth
Lithium Disilicate (CAD/CAM) Fixed Partial Dentures (FPD) Clinical Study
This investigation will be a clinical trial to study the performance of a high strength ceramic material for bridges to replace missing teeth. The ceramic material has been approved by the FDA for patient treatment.
- Trial name
- NCT03036566
- Testing
- Lithium disilicate ceramic (Ivoclar)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Molar Hypomineralization, Incisor
Comparison of the Long-Term Success of Different CAD-CAM Blocks Used as Indirect Restorations in Molar Incisor Hypomineralized Teeth: A Split Mouth Study
This study is about the long-term survival success of different, externally prepared fillings (Indirect restoration, CAD-CAM blocks) used in teeth with reduced mineral structure, namely Molar Incisor Hypomineralization (MIH)…
- Trial name
- NCT07144605
- Testing
- CAD-CAM, indirect restorations
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Enamel Hypoplasia, Molar-Incisor Hypomineralization (MIH)
Clinical Comparison of CAD/CAM Nanohybrid Composite and Hybrid Ceramic Overlays in Children With Molar-Incisor Hypomineralisation
This clinical study was conducted to compare two different dental materials used in the treatment of children who have a condition called molar-incisor hypomineralization (MIH).
- Conditions
- Enamel Hypoplasia, Molar-Incisor Hypomineralization (MIH), Restoration of Permanent Molars Affected by MIH With CAD/CAM Blocks
- Trial name
- NCT06987448
- Testing
- Semi-direct onlay restoration using CAD/CAM hybrid composite block, Semi-direct onlay restoration using CAD/CAM hybrid ceramic block
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Alp Akça
Implant Complication
Digital Versus Conventional Impression CAD\CAM Constructed 4- Implant Supported Mandibular Overdenture Base
This clinical study was done to compare between digital with conventional impression used in the CAD/CAM constructed 4- implant supported mandibular overdenture base regarding their effect on the bone height changes
- Trial name
- NCT06071676
- Testing
- conventional impression group, digital impression group
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Maxillary Sinus, Allograft
Maxillary Sinus Augmentation Using CAD/CAM Allogenic Bone Blocks Versus Particulate Allogenic Grafts
28 patients will be included in this study with atrophic posterior maxillary ridge due to sinus pneumatization who will randomly assigned to two groups Group I: sinus lifting using CAD/CAM allogenic block through lateral window…
- Trial name
- NCT07604155
- Testing
- sinus lifting using CAD/CAM allogenic block, sinus lifting using particulate allogenic graft
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Tanta University
Edentulous Jaws
Computer Assisted Implant Surgery and Immediate Loading
Purpose: The aim of this study was to analyze the clinical and radiographic outcomes of 23 edentulous jaws treated with 3D software planning, guided surgery, immediate loading and restored with Cad-Cam Zirconia and titanium full…
- Trial name
- NCT01866696
- Testing
- oral implants
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Università degli Studi di Sassari
Atrophy of Edentulous Alveolar Ridge
the Effect of Hyaluronic Acid on a Prefabricated CAD-CAM Bone Blocks for Ridge Augmentation
Each patient will receive 2 prefabricated CAD-CAM allogeneic bone blocks sterilized with gamma rays with different rehydration methods.
- Trial name
- NCT06395818
- Testing
- prefabricated CAD-CAM allogeneic bone block hydrated using hyaluronic acid, prefabricated CAD-CAM allogeneic bone block sterilized hydrated using saline solution
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tanta University
Edentulous Jaw, Dental Prosthesis Complication
Performance of CAD/CAM Milled and 3D-printed Full-arch Implant-supported Provisionals Restorations
This clinical trial aims to compare the performance of CAD/CAM-milled and 3D-printed full-arch implant-supported provisional restorations in patients at the Advanced Implant Prosthetics Clinic of the Complutense University of…
- Conditions
- Edentulous Jaw, Dental Prosthesis Complication, Dental Prosthesis Failure
- Trial name
- NCT05958043
- Testing
- 3D- printed Full-arch Implant-supported Provisionals Restorations, CAD/CAM-milled Full-arch Implant-supported Provisionals Restorations
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Denture,Complete, Edentulous Alveolar Ridge
Conventional Versus 3D Printing Duplication Techniques of Complete Denture
Twenty completely edentulous patients with old, removable dentures with ill-fitting maxillary dentures, proper vertical dimension, and proper occlusion will be recruited for this trial.
- Trial name
- NCT06588140
- Testing
- Duplicated refitted complete denture made from conventionally heat-cured polymethyl methacrylate., Duplicated refitted complete denture made from 3D-printed CAD/CAM pink polymethylmethacrylate acrylic resin., Duplicated refitted complete denture made from 3D-printed CAD/CAM white polymethylmethacrylate acrylic resin.
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Prefabricated, CAD
Prefabricated CAD CAM Allogeneic Ring Blocks in the Anterior Maxilla With Immediate Implantation
Clinical and radiographic evaluation of a new modification of ring technique using omputeraided design/computer-aided manufacturing (CAD/CAM) milling of allogeneic bone block for anterior maxilla ridge augmentation with immediate…
- Conditions
- Prefabricated, CAD, CAM, Allogeneic Ring Blocks
- Trial name
- NCT07163351
- Testing
- CAD/CAM allogenic bone block
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Mandibular Tumors
Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using FFF With and Without CAD/CAM Customized Cutting Guide
The purpose of this study is to compare Aesthetic results and operation time of free fibular flap with and without CAD/CAM customized osteotomy guide for reconstruction of mandibular defects.
- Trial name
- NCT03757273
- Testing
- FFF with CAD/CAM customized cutting guide, FFF without customized cutting guide
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Orthodontic Retainers
Comparison Between CAD/CAM and Conventional Mandibular Fixed Retainers.
The devices compared in this study are 'retainers', i.e. fixed orthodontic retainers applied to the lingual surface of the central and lateral incisors and lower canines bilaterally.
- Trial name
- NCT06529601
- Testing
- CAD/CAM mandibular fixed retainer, Conventional mandibular fixed retainer
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Decay
Clinical Evaluation of Lava Digital Veneer System (DVS) Crowns
Study aim is to compare Lava Computer Aided Design / Computer Aided Milling Computer Aided Machining (CAD/CAM)crowns that are veneered (covered) with porcelain that has been milled using CAD/CAM, with similar CAD/CAM Lava crowns…
- Trial name
- NCT01278862
- Testing
- DVS veneer, Conventional Veneer
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Solventum US LLC
Speech, Denture, Partial, Removable
Intelligibility and Acoustic Speech Performance of CAD/CAM Milled Titanium Partial Dentures
Partial dentures play a crucial role in restoring oral function and aesthetics for patients with missing teeth. Traditionally, these prostheses have been fabricated using materials such as acrylic resin or cobalt-chromium alloys.
- Conditions
- Speech, Denture, Partial, Removable, CAD-CAM
- Trial name
- NCT06589570
- Testing
- Removable Partial Denture
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Badr University