Clinical trials: CAD-CAM, open to volunteers
Maxillary Diseases
Patient Satisfaction & Abutment Teeth Health in Maxillectomy Patients
randomized controlled trial in maxillectomy patients with two types of obturators with different manufacturing techniques
- Trial name
- NCT06934551
- Testing
- obturator
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Hyaluronic Acid (HA)
A Comparative Clinical Assessment of Adjunctive Hyaluronic Acid With 3D Printed Versus Milled CAD CAM Provisional Dental Restorations on Active Periodontal Status and Surface Roughness and Biocompatibility
A Comparative Clinical Assessment of Adjunctive Hyaluronic Acid with 3D Printed Versus Milled CAD CAM Provisional Dental Restorations on active Periodontal status and Surface Roughness and biocompatibility (A Randomized…
- Trial name
- NCT07625839
- Testing
- commonly used hyaluronic Acid with both procedures 3D Printed Versus Milled CAD CAM Provisional Dental Restorations
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries Lesion of Pemanent Teeth
Adjustment Period for Partial Crowns
The aim of this study is to compare the occlusal accuracy of CAD/CAM milled and 3D printed crowns guided by an occlusal device, starting from the same digital CAD design.
- Trial name
- Adjustment per (NCT07051590)
- Testing
- cad cam, 3D printer
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ceren Sire
Tooth Discoloration, Tooth Staining
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without…
- Trial name
- NCT07464197
- Testing
- Customized bleaching tray fabrication, Reservoir tray design, Carbamide peroxide 10%
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Transverse Maxillary Deficiency
Digital vs. Analog Inputs in CAD/CAM Orthodontics: A Comparative Clinical Evaluation of Palatal Expander Fabrication Workflow
36 patients with unilateral or bilateral cross bite treated with hyrax expanders fabricated through three distinct workflows: fully conventional (physical impression + manual fabrication), hybrid (physical impression + CAD/CAM…
- Trial name
- NCT07338591
- Where
- 2 sites in Egypt
- Volunteers
- 36 people
- Sponsor
- Mansoura University
Dental Disorders Hard Tissues of Teeth, Dental Diseases
Clinical Evaluation of Full Contour Zirconia Chairside CAD/CAM Crowns
This investigation will be a randomized, prospective, longitudinal clinical trial to study the clinical performance of a new monolithic, zirconia material with shade, translucency and material graduation for chairside CAD/CAM…
- Trial name
- NCT06173167
- Testing
- Crowns self-adhesively luted, Crowns conventionally cemented
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG
Edentulous Alveolar Ridge
Monolithic Zirconia With CAD/CAM Titanium Abutments: A 5-year Prospective Case Series Study
Background There is a growing interest in restoring function in the posterior maxilla and mandible with dental implants. Next to this, these implants must be restored with crowns which are subject to minimal complications.
- Trial name
- NCT06110611
- Testing
- Astra Tech Osseospeed EV® dental implant
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- University Medical Center Groningen
Tooth Loss, Dental Implant
A 36-month Analysis of the Clinical Performance of Individualized CAD/CAM-produced Dental Implants: a Cohort Study
The goal of this prospective cohort study is to evaluate the clinical performance of a new generation of customized CAD/CAM pre-fabricated root-analog dental implants over a 36-month period.
- Trial name
- NCT06576284
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Occlusion, Occlusal Splints
Clinical Performance of CAD/CAM Occlusal Splints Fabricated With or Without a Wax Bite Registration in Healthy Adults
Occlusal splints are commonly used to manage sleep bruxism, temporomandibular disorders, and tooth wear. Traditionally, a wax bite registration is used during the fabrication of CAD/CAM occlusal splints to determine the vertical…
- Conditions
- Occlusion, Occlusal Splints, Occlusal Analysis, Comfort
- Trial name
- Splint (NCT07720453)
- Testing
- Occlusal splint fabricated using a virtual increase of the vertical dimension, Occlusal splint fabricated using a conventional wax bite registration
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Dental Restorations Longevity
3D-Printed Versus CAD/CAM-Milled Resin Restorations in Posterior Teeth.
Indirect resin restorations had become a well-established conservative alternative to direct composite restorations in posterior teeth, particularly in cases of significant loss of tooth structure requiring cuspal coverage…
- Trial name
- NCT07811167
- Testing
- 3D-Printed Resin Onlay/Overlay (saremco print CrownTec®), Milled Resin Onlay/Overlay (Brilliant Crios)
- Volunteers
- 70 people
- Sponsor
- University of Valencia
Indirect Tooth-colored Onlay Restorations in Posterior Teeth, Clinical Performance of Cervical-margin-relocated Onlay Restorations
Clinical Evaluation of Indirect Tooth-Colored Onlays With Cervical Margin Relocation
This study will evaluate the performance of three different tooth-colored onlay materials in adult patients' posterior teeth. First, investigators will use a bulk-fill composite resin to raise the cavity margin above the gum line…
- Trial name
- NCT07157410
- Testing
- Machinable lithium-disilicate ceramic onlay (IPS e.max CAD), Pressed lithium-disilicate ceramic onlay (IPS e.max Press), Machinable composite onlay (BRILLIANT Crios)
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Endodontically Treated Molar, Dental Restoration, Permanent
3D Printed Ceramic-Filled Photopolymer Resin Vs. CAD/CAM Resin Composite Overlays for Restoration of Extensively Damaged Endodontically Treated Posterior Teeth. An 18-month Follow-up
II. Introduction: 6. Background and rationale: Restoring badly mutilated teeth was and has always been a challenge in restorative dentistry.
- Trial name
- 3D CAD/CAM RCT (NCT07378982)
- Testing
- 3D printed overlay restorations, CAD/CAM restorations
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
CAD/CAM, Patient Specific Implant
Tooth and Bone-borne Cutting/Repositioning Guide and Patient-specific Implant(PSI)
Dentofacial deformity refers to a group of disorders characterized by malocclusion and facial asymmetry resulting from developmental abnormalities of the maxilla and mandible, which cause morphological and positional anomalies of…
- Conditions
- CAD/CAM, Patient Specific Implant, Orthognathic Surgery, Surgery-first
- Trial name
- PSI (NCT07634276)
- Testing
- bimaxillary surgery(Lefort I and SSRO)
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College
Edentulism, Dental Implants
Accuracy of the Calibrated Framework for Intra Oral Full Arch Scan (A Cross-over Study)
This crossover clinical trial aims to compare the accuracy of conventional splinted open-tray implant impressions with intraoral digital scanning using a calibrated framework in completely edentulous patients rehabilitated with…
- Trial name
- NCT07858682
- Testing
- Conventional Splinted Open-Tray Implant Impression, Intraoral Digital Scanning Using a Calibrated Framework
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Occlusion, Prosthesis Durability
Abutment Analysis of Metallic Denture Frameworks in Mandibular Kenedy Class III Cases
This study is aimed to compare CAD/CAM (digitally fabricated) metallic partial denture frameworks to conventionally fabricated metallic partial denture frameworks in mandibular Kennedy class-III arches in terms of abutment health…
- Trial name
- NCT07215208
- Testing
- CAD/CAM metallic partial denture frameworks, Conventional metallic partial denture frameworks
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Loss
Allogenic Bone Block for Oro-Antral Communication Closure for Subsequent Implant Placement
13 patients will be included in this study with a badly destructed upper molar indicated for extraction. Cone beam computerized tomography images revealed the presence of a large bone defect associated with oro-antral…
- Trial name
- CAD-CAM (NCT07604142)
- Testing
- Extraction will be performed atraumatically using a piezotome surgical motor with an extraction kit
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Tanta University
Socket Preservation, Implant-supported Single Crowns
Hyaluronic Acid and Polynucleotides in Ridge Preservation
The aim of this study is to test the use of a bovine-derived bone graft combined with a polynucleotides-rich hyaluronic acid (PNHA) gel for the preservation of the bone after a tooth extraction (alveolar ridge preservation) and…
- Conditions
- Socket Preservation, Implant-supported Single Crowns, Hyaluronic Acid, CAD-CAM
- Trial name
- P-005 (NCT07099846)
- Testing
- regeneration of post extraction socket with biomaterials
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- University of Parma
Partially Edentulous Mandible
Artificial Intelligence Assisted Workflow Versus Conventional Workflow in Guided Implant Placement
The AI assisted CAD/CAM workflow will be adopted for the treatment planning and guide design generation with the aim of comparing precision of implant placement with conventional digital workflow.
- Trial name
- Implant (NCT07523815)
- Testing
- AI assisted implant placement, Conventional computer guided implant placement
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sandra Moussa Botros El Tarzi
Foot Deformities, Orthotic Device
Custom CAD/CAM Insoles for Plantar Pressure Improvement in Foot Deformities
This randomized controlled trial will investigate the effects of custom CAD/CAM insoles on plantar pressure distribution and gait parameters in individuals with foot deformities, such as pes planus, pes cavus, and hallux valgus.
- Conditions
- Foot Deformities, Orthotic Device, 3D Printing, CAD
- Trial name
- NCT07136649
- Testing
- Custom CAD/CAM Insoles
- Volunteers
- 30 people
- Sponsor
- Fenerbahce University
CAD-CAM, Patients Specific Manufacturing
Analysis of Mandibular Proximal Segment Position Using Virtual Orthognathic Surgical Planning, Individualized Guides, and Osteosynthesis Plates
Orthognathic surgery is a surgical procedure performed to correct dentofacial deformities. In recent years, with the use of virtual surgical planning, cutting guides, and patient-specific osteosynthesis plates, highly predictable…
- Conditions
- CAD-CAM, Patients Specific Manufacturing, Osteotomy, Sagittal Split Ramus
- Trial name
- NCT06442787
- Testing
- conventional splints, cutting guides and positioning guides, cutting guides and fixation plates
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University