Clinical trials: CATARACT SURGERY
Cataract Surgery
Comparison of Two Phacoemulsification Systems in Cataract Surgery (UNITY VCS vs. Centurion)
This prospective, randomized, contralateral (crossover) study compares the ultrasound efficiency and early postoperative outcomes (Day 1 and Day 7) of two phacoemulsification platforms - the UNITY® VCS system with 4D Phaco and…
- Trial name
- COMPASS (NCT07756385)
- Testing
- UNITY VCS SYSTEM ®, CENTURION VISION SYSTEM ®
- Where
- Croatia
- Volunteers
- 30 people
- Sponsor
- University Hospital Sveti Duh
Cataract Surgery
The Effect of Hand Holding and Stress Ball Intervention on Pain and Anxiety
Cataract surgery is currently primarily performed with topical anesthesia. Although topical anesthesia provides many benefits for patients, they may experience pain, anxiety and discomfort during surgery.
- Trial name
- NCT07108192
- Testing
- Hand Holding, Stress Ball, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Sakarya University
Pain, Fear
Stress Ball Use During Cataract Surgery: Effects on Pain, Fear and Satisfaction
The aim of this study is to determine the effect of stress ball use during cataract surgery on patients' pain, fear, and satisfaction levels.
- Conditions
- Pain, Fear, Stress Ball, Nursing
- Trial name
- SBUDCS (NCT07452770)
- Testing
- Use of a stress ball during cataract surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Bezmialem Vakif University
Cataract Surgery, Intraocular Lens Position
The Effect of Capsulotomy Size on Effective Lens Position in Robotic Laser Cataract Surgery
The goal of this clinical trial is to learn whether the size of the opening made during laser-assisted cataract surgery affects where the artificial lens sits in the eye and the glasses prescription after surgery.
- Conditions
- Cataract Surgery, Intraocular Lens Position, Refractive Outcomes After Cataract Surgery, Cataract
- Trial name
- PRECISE (NCT07856849)
- Testing
- Femtosecond Laser Capsulotomy - Small Size (4.6 mm), Femtosecond Laser Capsulotomy - Large Size (5.6 mm)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Twin Cities Eye Consultants
Cataract, Cataract (Post-operative Cataract Surgery Follow-up)
Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery
This randomized controlled trial evaluates whether a standardized perioperative neuroplastic intervention: the STEIN Protocol (Strategies and Techniques for Enhancing Integration and Neuroplasticity), consisting of pain…
- Trial name
- SLin (NCT07715591)
- Testing
- Music and Guided Imagery, Control, Music Only
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of California, Los Angeles
Dry Eye, Ocular Surface Disease
Evaluation of Lacrifill
Dry Eye Disease is defined as "a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface.
- Conditions
- Dry Eye, Ocular Surface Disease, Cataract Surgery, Eyes Dry Feeling of
- Trial name
- NCT07796178
- Testing
- Lacrifill, Saline
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Eye Research Associates, LLC
Phacoemulsification Cataract Surgery, Capsular Tension Ring
Capsular Tension Ring With Hydrophilic Versus Hydrophobic Intraocular Lenses
This study compares three approaches to cataract surgery. Cataract surgery involves removing the eye's cloudy natural lens and replacing it with an artificial intraocular lens (IOL) to restore clear vision.
- Conditions
- Phacoemulsification Cataract Surgery, Capsular Tension Ring, IOL Implantation
- Trial name
- CTR-IOL-3ARM (NCT07842809)
- Testing
- Hydrophilic acrylic intraocular lens (Eyecryl), Capsular tension ring (Auroring CTR 11), Hydrophobic acrylic intraocular lens (AcrySof IQ)
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Benha University
Cataract, Surgery
Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population
The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the…
- Conditions
- Cataract, Surgery, Compliance, Patient, Compliance, Medication
- Trial name
- NCT05157113
- Testing
- Dropless Regimen, Standard Regimen
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of California, San Francisco
Cataract Surgery
Pilot Study: Feasibility and Usability of a Head-Mounted Spatial Computing Device for Intraoperative Visualization During Intraocular Surgery
To evaluate the feasibility and usability of Apple Vision Pro as an adjunct visualization and information display tool during ophthalmic surgery.
- Trial name
- NCT07825337
- Testing
- Apple Vision Pro Visualization System
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Eric Rosenberg
Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up)
Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery
The main goal of the sub-incisional pocket (SIP) is to provide a wound seal option during corneal surgery. This retrospective cohort study aims to report the efficacy and safety of SIP among eyes undergoing routine cornea surgery…
- Conditions
- Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up), Phacoemulsification Cataract Surgery, Wound Closure Technique
- Trial name
- SIPSIP (NCT07821203)
- Testing
- Sub-Incisional Pocket
- Where
- Philippines
- Volunteers
- 35 people
- Sponsor
- Philippine Eye Research Institute
Vitreous Detachment, Cataract (Post-operative Cataract Surgery Follow-up)
Evaluation of Vitreous Modifications After Cataract Surgery
This study aims to evaluate changes in vitreous structure and the vitreoretinal interface following cataract surgery using spectral-domain optical coherence tomography (OCT).
- Trial name
- VitCat (NCT07816887)
- Testing
- cataract surgery
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University of Trieste
Dry Eye, Dry Eye Disease (DED)
Temporary Tear Duct Filling With Hyaluronic Acid Gel and Assessment of Dry Eye Disease (DED) After Bilateral Cataract Surgery
Dry eye disease can occur or worsen after cataract surgery and may cause ocular discomfort and reduced visual quality. Standard treatment commonly includes artificial tear eye drops, which provide temporary lubrication.
- Conditions
- Dry Eye, Dry Eye Disease (DED), Dry Eye Sensation After Cataract Surgery
- Trial name
- TANAMI (NCT07809022)
- Testing
- LACRIFILL® Canalicular Gel administration
- Where
- Austria
- Volunteers
- 25 people
- Sponsor
- Medical University of Vienna
Cataract Surgery Deneyimi, Cataract Surgery
Katarak Surgery and Care
Although cataract surgery is an effective treatment method for improving visual function, it is important to evaluate the quality of life, daily living activities, independence level and psychosocial well-being of patients in the…
- Trial name
- NCT07807761
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Cataract and IOL Surgery, Keratoplasty
Postoperative Outcomes of a Toric AddOn Intraocular Lens After Keratoplasty and Cataract Surgery
The aim of this clinical study is to evaluate a toric add-on intraocular lens (IOL) for the correction of high astigmatism in patients who have undergone keratoplasty and cataract surgery.
- Conditions
- Cataract and IOL Surgery, Keratoplasty, Toric Intraocular Lens Stability
- Trial name
- AddOn (NCT07452042)
- Testing
- AddOn toric IOL implantation
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Corneal Edema After Cataract Surgery
A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery
The purpose of this study is to assess the safety and efficacy of K-321 in subjects after cataract surgery
- Trial name
- NCT05528172
- Testing
- Ripasudil
- Where
- 45 sites in United States, Puerto Rico
- Volunteers
- 330 people
- Sponsor
- Kowa Research Institute, Inc.
Pseudophakic Macular Edema, Diabetic Nephropathies
Diabetic Nephropathy, Glycemic Control and Pseudophakic Macular Edema After Cataract Surgery
This retrospective cohort study examines whether the kidney complications of diabetes (diabetic nephropathy) and blood-sugar control before surgery help predict swelling of the central retina, called pseudophakic macular edema…
- Conditions
- Pseudophakic Macular Edema, Diabetic Nephropathies, Diabetes Mellitus, Type 2, Cataract (Post-operative Cataract Surgery Follow-up)
- Trial name
- NCT07723846
- Testing
- Phacoemulsification with posterior-chamber IOL
- Where
- Thailand
- Volunteers
- 428 people
- Sponsor
- Thammasat University Hospital
Glaucoma, Open Angle, MIGS
Three Year Outcomes of Combined Hydrus Microstent With iTrack Canaloplasty
The goal of this study is to learn if combining minimally invasive glaucoma surgery (MIGS) procedures with different mechanisms of action increases the effectiveness of MIGS.
- Conditions
- Glaucoma, Open Angle, MIGS, Minimally Invasive Glaucoma Surgery, Canaloplasty
- Trial name
- NCT07073937
- Testing
- Retrospective chart review
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Post-Operative Cognitive Decline in Older Adults, Post-operative Cognitive Decline
Post-operative Cognitive Decline After Ambulatory Cataract Surgery in the Elderly Population
Postoperative cognitive decline is a recognized complication following anesthesia and surgery in older adults; however, its incidence after ambulatory cataract surgery performed under sedation is not well understood.
- Conditions
- Post-Operative Cognitive Decline in Older Adults, Post-operative Cognitive Decline, Perioperative Neurocognitive Disorders, Cataract Surgery Anesthesia
- Trial name
- NCT07714174
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Cataract, Cataract Surgery
Outcomes of High vs Physiological Intraocular Pressure During Cataract Surgery Using ACTIVE SENTRY
Cataract surgery is a widely performed procedure across the world that helps restore vision in many patients suffering from cataracts. Irrigation is an essential component of the surgery.
- Conditions
- Cataract, Cataract Surgery, Cataract Bilateral
- Trial name
- ACTIVESENTRY (NCT06611670)
- Testing
- Cataract surgery with Active Sentry, Traditional cataract surgery
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Dry Eye Disease (DED), Cataract Surgery
POST CATARACT SURGERY DRY EYE DISEASE
Cataract surgery is one of the most frequent and successful interventions currently undertaken in medicine. However, a significant number of patients who underwent cataract surgery still complain about postoperative symptoms…
- Trial name
- NCT07715266
- Testing
- NOX-01
- Where
- 2 sites in Spain
- Volunteers
- 33 people
- Sponsor
- NOXELIS