Clinical trials: CATARACT SURGERY
Fuchs Endothelial Corneal Dystrophy, Cataract (Post-operative Cataract Surgery Follow-up)
Postoperative CCT in FECD vs. Non-FECD
This single-centre, prospective, controlled, non-interventional observational clinical study aims to characterize early postoperative corneal thickness behaviour after routine phacoemulsification cataract surgery in eyes with…
- Trial name
- NCT07731945
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Vienna Hospital Association
Corneal Endothelial Cell Loss, Corneal Endothelial Damage Following the Hard Nuclear Cataract Surgery
A Study of CA201A Eye Drops to Prevent Corneal Endothelial Cell Loss in Patients Undergoing Cataract Surgery
This study is designed to assess whether an investigational eye drop called CA201A can help protect the cornea (the outer covering of the eye) and reduce damage to corneal endothelial cells following cataract surgery, without…
- Trial name
- NCT07694375
- Testing
- Ophthalmic solution (matching formulation without ascorbic acid), Ascorbic acid ophthalmic solution 5%
- Where
- 8 sites in Australia
- Volunteers
- 200 people
- Sponsor
- Caravel Oculus Pty Ltd
VR-based Informed Consent, Cataract and Intraocular Lens Surgery
VR for Cataract Anxiety Lowering Management
Cataract is currently the leading cause of blindness globally, and surgery is the only effective treatment. With the advancement of medical technology, cataract surgery is usually performed under topical anesthesia, which means…
- Trial name
- VR-CALM (NCT07586280)
- Testing
- Virtual reality simulation of intraoperative audiovisual experience
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Cataract and IOL Surgery, VR-based Informed Consent
VR for Cataract Anxiety Lowering Management--A RCT Study
Cataract is currently the leading cause of blindness globally, and surgery is the only effective treatment. With the advancement of medical technology, cataract surgery is usually performed under topical anesthesia, which means…
- Trial name
- VR-CALM (NCT07620821)
- Testing
- Virtual reality simulation of intraoperative audiovisual experience
- Where
- China
- Volunteers
- 223 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Cataract Surgeries
Comparison of the Concordance Between Digital Marking and Manual Marking for Toric Intraocular Lens Positioning
This cross-sectional comparative study evaluated patients from a single cataract center. In each eye, manual horizontal meridian axis line was marked on the cornea using the manual peripheral corneal marking technique (Horizontal…
- Trial name
- NCT07710963
- Testing
- Verion Digital Marking
- Volunteers
- 100 people
- Sponsor
- Thammasat University
Cataract Surgery Anesthesia
Study of Remimazolam for Cataract Surgery
The goal of this clinical trial is to learn if the use of the sedative remimazolam improves the safety of patients having cataract surgery by decreasing the number of sedation-related complications during and after surgery, and…
- Trial name
- NCT07325227
- Testing
- Arm 1 Cataract Surgery performed with remimazolam as sedative, Arm 2 Cataract Surgery performed with standard of care sedative
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fred E, Shapiro
Cataract, Cataract (Post-operative Cataract Surgery Follow-up)
Evaluation of Visual Outcomes, Complications, and Neuroadaptation Following Bilateral Implantation of enVista Envy Trifocal Intraocular Lenses
The enVista Envy intraocular lens (IOL) manufactured by Bausch + Lomb is a new multifocal intraocular lens based on diffractive optics.
- Trial name
- NCT07696130
- Testing
- cataract surgery
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Pomeranian Medical University Szczecin
Cataract Surgery, Eye Care
Effect of Vision Centers on Access to Eye Care and Eye Health Outcomes
This cluster-randomized trial aims to evaluate the effect of vision centers on access to eye care and eye health outcomes in South Asia. The main questions it aims to answer are: 1.
- Conditions
- Cataract Surgery, Eye Care, Glasses, Primary Eye Care
- Trial name
- NCT07227714
- Testing
- Establishment of a vision center
- Where
- United States
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dexmedetomidine, Dexamethasone
Dexmedetomidine Versus Dexamethasone as an Additive to Local Anesthetic Mixture in Peribulbar Block in Cataract Surgeries
This study aimed to compare the effects of dexamethasone and dexmedetomidine when added to a local anesthetic mixture for peribulbar block in patients undergoing elective anterior segment eye surgery.
- Conditions
- Dexmedetomidine, Dexamethasone, Local Anesthetic, Peribulbar Block
- Trial name
- NCT07671066
- Testing
- Dexmedetomidine, Dexamethasone, Normal saline
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Helwan University
Cataract Surgery, Cataract
Evaluation of Head-Mounted Spatial Computing and Three-Dimensional (3D) Visualization in Ocular Microsurgery: A Safety and Workflow Study
The purpose of this research is to evaluate the use of the research study device, the Apple Vision Pro head-mounted spatial computing display, with the Zeiss Artevo 850 digital microscope system, for the visualization during…
- Trial name
- NCT07301385
- Testing
- Apple Vision Pro (Head-Mounted Spatial Computing Display), Zeiss Artevo Digital Surgical Microscope
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Sharp HealthCare
Cataract and IOL Surgery
Comparing Visual Outcomes in Matched Patients Receiving a Low Cylinder Power Toric IOL or a Non-toric IOL
The purpose of the study is to determine if visual function is improved with implantation of a low-cylinder toric intraocular lens, relative to a non-toric intraocular lens.
- Trial name
- NCT06717607
- Testing
- low cylinder toric IOL, non-toric IOL implantation
- Where
- Norway
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Ifocus Oyeklinikk
Cataract (Post-operative Cataract Surgery Follow-up), Refraction Error
Can Tailored Surgical Incisions Reduce Refractive Error and Dependence on Glasses After Cataract Surgery?
Astigmatism is a common cause of continued dependence on glasses after cataract surgery and may lead to patient dissatisfaction with surgical outcomes.
- Trial name
- AST-2 (NCT07623317)
- Testing
- Adapted clear corneal incisions
- Volunteers
- 100 people
- Sponsor
- Linkoeping University
Cataract, Cataract Surgery
Binocular and Monocular Distance-Corrected Visual Performance and Defocus Characteristics of Clareon Truplus Intraocular Lens (IOL)
This study aims to generate data that characterizes visual outcomes, including the binocular distance-corrected intermediate visual acuity (DCIVA) at 66cm or defocus behavior, of the Clareon TruPlus modified monofocal intraocular…
- Conditions
- Cataract, Cataract Surgery, Cataract Bilateral, Cataract (Post-operative Cataract Surgery Follow-up)
- Trial name
- BMVDI (NCT07589894)
- Testing
- Clareon TruPlus IOL
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Colvard Kandavel Eye Center
Cataract Surgery
A Prospective Multicenter Study To Assess The Clinical Outcomes Of Current Phacoemulsification Approach To Cataract Extraction Versus The Micor System Device
The purpose of this research study is to evaluate the clinical outcomes of current phacoemulsification approaches to cataract extraction involving high-frequency thermogenic energy versus the use of the MICOR System device using…
- Trial name
- NCT05729477
- Testing
- miCOR System, Phaco Subject Cohort
- Where
- 6 sites in United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Hydration, Cataract Surgery
Posterior Flap Hydration of Clear Corneal Incisions in Cataract Surgery: Influence on Corneal Wound Tightness and Architecture
Sutureless clear corneal incision (CCI) is the most commonly used technique for creating an entrance wound in cataract surgery. Corneal incision hydration enhances wound tightness and reduces postoperative fluid suction from the…
- Trial name
- CCI hydration (NCT07581366)
- Testing
- Patient with visible central wound gap of the CCI
- Where
- Czechia
- Volunteers
- 53 people
- Sponsor
- University Hospital Pilsen
Cataract Surgery
Reducing Patient Waiting Time for Cataract Surgery
The purpose of this study is to examine how coordination between hospital departments affects patient flow between the free ward (B1), paid ward (C1) and the operating theatre (OT) for cataract surgeries at a tertiary eye care…
- Trial name
- NCT07484659
- Testing
- Standard Operating Procedures (SOPs)
- Where
- India
- Volunteers
- 360 people
- Sponsor
- Seva Canada Society
Cataract Surgery, Sedation
Oral vs IV Sedation for Cataract Surgery in Older Adults
The goal of this clinical trial is to evaluate the feasibility of comparing oral sedation (a pill) with intravenous (IV) sedation for cataract surgery in older adults.
- Conditions
- Cataract Surgery, Sedation, Cognition Function, Perioperative Care
- Trial name
- CatNAPS-2 (NCT07154147)
- Testing
- Alprazolam, Midazolam
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Ophthalmology, Cataract Surgery Anesthesia
An Extension Test of Whether to Use Oral Anti-anxiety Drugs (Alprazolam) When Patients Choose Second Eye Cataract Surgery After Unblinding, and Analyze Their Anxiety, Satisfaction and Pain Satisfaction
Phacoemulsification is one of the most used surgical methods for cataract surgery today, and the surgeries are under the anesthetic and sedative to make it comfortable and safe for patients.
- Conditions
- Ophthalmology, Cataract Surgery Anesthesia, Oral Anxiolytic, Satisfaction Survey
- Trial name
- NCT06874452
- Testing
- Alprazolam (Xanax)
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- National Taiwan University Hospital
Safety, Efficacy
Bilateral Peribulbar Block for Cataract Surgery
This study aims to evaluate the safety and efficacy of bilateral peribulbar block for cataract surgery.
- Conditions
- Safety, Efficacy, Bilateral, Peribulbar Block
- Trial name
- NCT07000669
- Testing
- Bilateral peribulbar block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Oral Anxiolytic, Phacoemulsification
Anxiety and Surgery Satisfaction for Cataract Patient With Different State Anxiety
This study aims to explore the effects of anxiety traits on pain, anxiety, and anesthesia satisfaction in patients undergoing cataract surgery under topical anesthesia.
- Conditions
- Oral Anxiolytic, Phacoemulsification, Cataract Surgery, Satisfaction Survey
- Trial name
- NCT06826417
- Testing
- Xanax
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital