Clinical trials: CMT
Carpal Tunnel Syndrome
Different Sessions of Perineural Injection With Dextrose for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT03802435
- Testing
- two-sessions of ultrasound-guided PIT, One-sessions of ultrasound-guided PIT
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Carpal Tunnel Syndrome (CTS)
Study of the Carpal Tunnel Syndrome in Relation to Stress and Depression Among Medical Students
Participants will undertake validation of the median nerve and their anxiety and depression levels. Possible correlation will be searched.
- Trial name
- CRS (NCT06758518)
- Testing
- No Interventions
- Where
- Greece
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Drop Foot
The Investigators Are Comparing Lidocaine and Papaverine Nerve Blocks to Determine Which Improves Blood Flow Better, Making the "Phoenix Sign" Clearer on Imaging. This Helps Accurately Diagnose Nerve Compression, Improving Patient Care
This pilot study aims to investigate the effects of nerve blocks in patients with diabetic peripheral neuropathy through a double-blinded, randomized trial involving 4 patients.
- Trial name
- NCT06919289
- Testing
- Infiltration of papaverine, Lidocaine infiltration
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- US Neuropathy Centers
Ultrasonography, Peroneal Neuropathies
High-resolution Ultrasound in Lower Extremity Nerves and Common Fibular Neuropathies.
This study establishes reference material of selected lower extremity nerves at pre-defined sites with high-resolution ultrasound.
- Trial name
- NCT03560505
- Testing
- Ultrasound protocol
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sándor Beniczky
Carpal Tunnel Syndrome
Ultrasonographic Measurements of the Median Nerve Before and After Splinting for Carpal Tunnel Syndrome
A prospective cohort follow-up study design is undertaken. Both males and females with mild to moderate carpal tunnel syndrome will receive standard-of-care wrist splint for 6 weeks and undergo follow up studies for data…
- Trial name
- NCT02038205
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Anterior Cutaneous Nerve Entrapment Syndrome
Effect of Abdominal Wall Injections on Abdominal Pain
This is a prospective cohort study of outpatient adults with chronic abdominal wall pain receiving abdominal wall injections, as part of their usual care, with lidocaine.
- Trial name
- NCT06121466
- Testing
- Abdominal wall injections with lidocaine 2%
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
CMT - Charcot-Marie-Tooth Disease, CMT1A
AUTONOMOUS DISORDERS IN CMT
Hereditary neuropathies are a phenotypically and genetically heterogeneous group of disorders. One of the most common forms is Charcot-Marie-Tooth neuropathy (CMT), which can be further divided into demyelinating (CMT1) and…
- Conditions
- CMT - Charcot-Marie-Tooth Disease, CMT1A, CMT (Charcot Marie Tooth Disease)
- Trial name
- CMT-autonom (NCT07570446)
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Carpal Tunnel Syndrome
Studying Finger-thumb Grip in Patients With Carpal Tunnel Syndrome
INTRODUCTION Carpal tunnel syndrome (CTS) is a common condition that results in impaired hand function. In cases of CTS the "pinch grip" force between the thumb and index finger becomes unnecessarily high to prevent objects from…
- Trial name
- NCT02830828
- Testing
- Investigation of precision pinch grip control
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Thomas Edward Pidgeon
Neuromuscular Diseases, Hemiparesis
Validation Study of Posturology Platforms for Evaluating Postural Control of Hemiparetic and Neuro-muscular Patients
The instrumental evaluation of standing postural control by posturographic analysis supplements the clinical evaluation and, as such, is recommended by the French National Authority for Health (HAS 2007).
- Conditions
- Neuromuscular Diseases, Hemiparesis, Charcot-Marie-Tooth Disease
- Trial name
- KPLATES (NCT04283175)
- Testing
- Posturological examination on KPlates and AMTI platforms, Berg Balance Scale (BBS)
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pelvic Pain, Vulvodynia
Psychosocial Factors and Central Sensitization in Chronic Pelvic Pain
The purpose of this study is to determine if the psychosocial factors in women with chronic pelvic pain are predisposing, precipitant or maintenance factors, and relate these factors with central sensitization and dysfunctional…
- Conditions
- Pelvic Pain, Vulvodynia, Pudendal Neuropathy
- Trial name
- NCT02856334
- Where
- 2 sites in Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Carpal Tunnel Syndrome
Decision Making in Hypothetical Carpal Tunnel Syndrome
Participants will be presented with a hypothetical scenario of carpal tunnel and asked to make a decision for that case.
- Trial name
- NCT03730376
- Testing
- Cost Information
- Where
- United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hereditary Spastic Paraplegia, SPG47
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia
The Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP) is focused on gathering longitudinal clinical data as well as biological samples (skin and/or blood and/or saliva) from male and female…
- Conditions
- Hereditary Spastic Paraplegia, SPG47, SPG50, SPG51
- Trial name
- HSP (NCT04712812)
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Charcot-Marie-Tooth Type 1A
Pilot Study to Evaluate Fatigue and Fatigability Profiles and Their Impact on Walking and Balance in Patients With Charcot-Marie-Tooth Type 1A Disease Using a Global Approach in Comparison to Healthy Volunteers
Charcot-Marie-Tooth disease type 1A is the most common form of inherited neuropathy that causes peripheral nerve damage in all four limbs.
- Trial name
- FatMobCMT1A (NCT07066683)
- Testing
- CLINICAL ASSESSMENT OF BODY FUNCTION (PROM AND PHYSICAL EXAMINATION) and ACTIVITIES AND PARTICIPATION
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Neurofilament Light Chain, Glial Fibrillary Acidic Protein
Analysis of NfL and GFAP in Different Dietary Patterns
This observational study aims to investigate the impact of different dietary patterns on brain tissue biomarkers in healthy young adults by measuring blood levels of NfL and GFAP.
- Conditions
- Neurofilament Light Chain, Glial Fibrillary Acidic Protein, GFAP, Vegan Diet
- Trial name
- NCT07312994
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Salzburger Landeskliniken
Stroke, Stroke (CVA) or TIA
The Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3)
Stroke is a major cause of death and disability worldwide, frequently resulting in persistent cognitive deficits among survivors.
- Conditions
- Stroke, Stroke (CVA) or TIA, Dementia, Vascular, Cerebrovascular Disorders
- Trial name
- IC3 (NCT05885295)
- Testing
- MRI brain, Blood tests, cognitive assessments
- Where
- United Kingdom
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Carpal Tunnel Syndrome
Gabapentin and Neural Mobilization Pain Reduction Effect Compared to Only Gabapentine
In the present investigation the pain reduction effects of a physiotherapy technique combined with pharmaceutical gabapentin treatment will be compared to those produced by gabapentin (only) treatment, in subjects who suffer the…
- Trial name
- NCT06778798
- Testing
- Median nerve neural mobilization and oral gabapentin, Gabapentin 300mg
- Where
- Venezuela
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Carpal Tunnel Syndrome
Musculoskeletal Health of the Upper Extremity in Emerging Health Professionals
Carpal tunnel syndrome is the most expensive upper extremity work-related musculoskeletal disorder, impacting 10 million people annually and costing employers up to $113,695 per incident.
- Trial name
- NCT02587897
- Testing
- Academic Coursework, Work-Related Hand Activities
- Where
- 3 sites in United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Charcot-Marie-Tooth Disease
Observational Study of Neuromuscular Function in CMT Type 1&2 and Healthy Controls
The primary aim of this study is to discover whether patients with CMT type 1 and 2 have neuromuscular junction transmission deficits.
- Trial name
- ESTABLISH (NCT04980807)
- Where
- 2 sites in United States, Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NMD Pharma A/S
Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment
"Ultrasound Measures and Clinical Outcomes in Healthy Individuals, Mild and Moderate Carpal Tunnel Syndrome Patients"
"This study aims to investigate ultrasonographic parameters of the median nerve in healthy individuals and patients with mild and moderate carpal tunnel syndrome (CTS).
- Conditions
- Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment, Electrophysiologic Study, Ultrasound
- Trial name
- NCT07408596
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Carpal Tunnel Syndrome
The Treatment of Carpal Tunnel Syndrome Using Thumb Pressure Along the Median Nerve
The purpose of this study is to find the efficacy of treating the muscles in the inside (biceps,pronator teres) of the arm in order to eliminate the carpal tunnel syndrome .The authors hypothesise that eliminating the trigger…
- Trial name
- NCT00634699
- Testing
- Active Comparator, ischemic compressions
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guy Hains Chiropractor