Clinical trials: CORE
Patients With Primary Liver Cancer (PLC) Undergoing Curative Surgical Procedures, Importance of Identifying Core Symptoms for Improving Symptom Management in PLC Patients
Postoperative Symptoms in Chinese Liver Cancer Patients: Network Analysis
Patients with primary liver cancer (PLC) experience a range of symptoms in the early postoperative period. Symptoms include cancer-related symptoms and adverse effects of treatment.
- Conditions
- Patients With Primary Liver Cancer (PLC) Undergoing Curative Surgical Procedures, Importance of Identifying Core Symptoms for Improving Symptom Management in PLC Patients, Application of Network Analysis as a Crucial Component of Cancer Care
- Trial name
- PSC-LCNA (NCT06419478)
- Testing
- postoperative symptoms
- Where
- China
- Volunteers
- 249 people
- Sponsor
- Mengmeng Yuan
Upper Crossed Syndrome
Cervical Position Sense, Core Stability, and Postural Balance in University Students With Upper Crossed Syndrome
This study aims to investigate the relationship between cervical position sense, core stabilization, and postural balance in university students aged 18-30 years with Upper Crossed Syndrome (UCS).
- Trial name
- NCT07577492
- Testing
- postural and balance assessment battery
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istinye University
Ventral Hernia, Ventral Incisional Hernia
The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery
Ventral hernia repair is among the most common operations performed in the United States each year, yet the great majority of patients receive no structured rehabilitation for the persistent pain, weakness, and functional loss…
- Conditions
- Ventral Hernia, Ventral Incisional Hernia, Post Operative Pain
- Trial name
- IMPACT (NCT07145099)
- Testing
- PT Group, Usual Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Breast Cancer
NOSTRA-Feasibility Study: A Study Looking at Ultrasound Guided Biopsies for Breast Cancer
A prospective non-randomised multi-centre feasibility study to assess if patients with residual cancer following dual-targeted neoadjuvant chemotherapy treatment for HER2-positive, ER-negative early breast cancer can be…
- Trial name
- NOSTRA (NCT04118192)
- Testing
- Tumour bed core biopsy
- Where
- 24 sites in United Kingdom
- Volunteers
- 72 people
- Sponsor
- University of Birmingham
Backache, Low
Core Muscle Stability on Low Back Pain and Quality of Life in Post- Menopausal Women
Low back pain, postural dysfunction, loss of balance control and stability are musculoskeletal changes that occur over life span due to aging process and are inevitable.
- Trial name
- NCT03902132
- Testing
- Core Stability exercises group, Traditional low back physical therapy group
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Sports Physical Therapy
Investigation of the Relationship Between Core Endurance and Awareness of Injury Prevention in Adolescent Basketball Players
Injuries occurring during adolescence can lead to serious long-term problems. Such injuries can cause athletes to take breaks from their sports and physically strain themselves.
- Trial name
- NCT06475833
- Testing
- Prone plank test, Side plank test, The Awareness of Sports Injuries Scales
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Tetraplegia, Hypothermia
Body Temperature in Persons With Tetraplegia When Exposed to Cold
The ability to maintain normal body core temperature (Tcore = 98.6°F) is impaired in persons with tetraplegia. Despite the known challenges to the ability of persons with spinal cord injury (SCI) to maintain Tcore, and the…
- Conditions
- Tetraplegia, Hypothermia, Mild Cognitive Impairment
- Trial name
- NCT01822535
- Testing
- Midodrine hydrochloride
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Functional Constipation
Core-Based Movement and Nutritional Counselling for Stress and Metabolic Outcomes in Overweight Women With Functional Constipation
This study will investigate the effect of core-based movement and nutritional counselling on stress, serum cortisol, and lipid profile in overweight women with functional constipation.
- Trial name
- NCT07694830
- Testing
- Guideline-Based Nutritional Counselling, Core-Based Movement Exercise Program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias
The primary purpose of this Registry is to assess procedural safety and long-term effectiveness of catheter ablations in the treatment of subjects with PAF, PsAF, and VA.
- Conditions
- Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Ventricular Arrhythmia
- Trial name
- REAL Registry (NCT04088071)
- Testing
- Catheter ablation
- Where
- 75 sites in United States, Canada
- Volunteers
- 20,000 people
- Sponsor
- Heart Rhythm Clinical and Research Solutions, LLC
Lumbar Disc Herniation
Imaging Characteristics of Chronic Lumbar Disc Herniation From the Perspective of Core Muscles and Subcutaneous Fat Tissue Thickness
Fat infiltration and atrophy of lumbar muscles are related to spinal degenerative conditions, which can be seen reliably on MRI scans of lumbar disc herniation (LDH) patients.
- Trial name
- ICCLDHPCMSFT (NCT05649592)
- Testing
- Magnetic Resonance Hydrolipid Separation Imaging
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Zhan Yunfan
Acute Myeloid Leukemia (AML)
Randomized Phase III Study of Intensive Chemotherapy With or Without Dasatinib (Sprycel™)
This is a randomized phase III open-label, multicenter trial evaluating standard induction therapy (daunorubicin [DNR] and cytarabine [Ara-C]) and consolidation therapy (high-dose cytarabine [HDAC]) with or without dasatinib in…
- Trial name
- NCT02013648
- Testing
- Dasatinib, Cytarabine, Daunorubicin
- Where
- 54 sites in Austria, Germany
- Volunteers
- 204 people
- Sponsor
- University of Ulm
Neuroendocrine Tumors
An Open-label, Multi-center, Expanded Access Study of Everolimus in Participants With Advanced Neuroendocrine Tumors (NETs) (Core Study) and an Extension Study to the Open-label, Multi-center, Expanded Access Study of Everolimus in Patients With Advanced NETs (E1)
This record combines the results of CRAD001K24133 and CRAD001K24133E1. The purpose of the CRAD001K24133 study was to evaluate the safety profile of everolimus in patients with advanced neuroendocrine tumors of pancreatic origin…
- Trial name
- NCT01595009
- Testing
- Everolimus (RAD001)
- Where
- 11 sites in Germany
- Volunteers
- 246 people
- Sponsor
- Novartis Pharmaceuticals
Diastasis Recti
Low Back Pain and Motor Control Dysfunction After Pregnancy- the Possible Role of Abdominal Rectus Muscle Diastasis
The aim of this study was to compare participants with increased symptoms after index pregnancy with those reporting no change in back pain or subjective movement control and analyzed their inter rectus distance (IRD).
- Trial name
- D2 (NCT05485844)
- Where
- Finland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Thoracic Kyphosis
Comparing Back Extensor and Core Stability Training in Kyphosis
To compare the effects of back extensor strengthening exercises versus core stability exercises on thoracic kyphosis in patients, assessing improvements in posture, spinal alignment, and overall functional outcomes
- Trial name
- NCT06888609
- Testing
- Back Extensor Strengthening Exercises, Core Stability Exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Body Temperature Changes, Heat Stress
Consecutive Occupational Heat Exposure With and Without Overnight Cooling
Extreme heat events are becoming more frequent, intense, and prolonged, increasing the risk of heat-related illness among workers exposed to hot environments.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07656519
- Testing
- Simulated occupational heat exposure with recovery at recommended indoor temperature limit, Simulated occupational heat exposure with recovery in an overheated indoor environment
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Core Exercises Training, Structural Exercises Training
Recovery Kinetics After Different Power Training Protocols (PTRecovery)
Muscle power is one of the most important parameters in almost every athletic action, expressing the ability of the human muscle to produce great amounts of force with the greatest possible speed.
- Conditions
- Core Exercises Training, Structural Exercises Training, Accentuated Eccentric Exercises Training, Control Condition
- Trial name
- PTRecovery (NCT04847427)
- Testing
- Core exercises training, Structural exercises training, Accentuated eccentric exercises training
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Vasospastic Syndrome
Effect of Systemic Cooling in Vasospasms
This study tests whether women with Vasospastic Syndrome (VS) react more intensive than controls with distal vasomotions and choroidal blood flow changes to internal cooling/warming and external cooling/warming.
- Trial name
- NCT00409123
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Temperature Change, Body
Temperature Monitoring in Cardiac Surgery: Agreement Between Different Clinical Methods
Observational study to compare core temperatures obtained by 6 methods in patients undergoing cardiac surgery under cardiopulmonary bypass.
- Trial name
- NCT04355013
- Testing
- Core emperature monitoring
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Core Temperature
Accuracy of Body Temperature Measurements Using the Esophageal Temperature Probe Inserted Through the Gastric Lumen of Supraglottic Airway Device
In general, 50-90% of patients undergoing surgery under general anesthesia are known to develop hypothermia during surgery. Due to hypothermia during surgery, the patient may cause coagulation disorders, wound infections…
- Trial name
- NCT04485923
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Sojin Shin
Prostate Cancer
Comparison of New SUREcore Biopsy of Needle to Standard of Care During Transperineal Prostate Biopsies
To study a novel biopsy needle system for performing transperineal prostate biopsy. Prostate biopsy remains the standard approach for prostate cancer detection.
- Trial name
- NCT06907446
- Testing
- Comparison of Biopsy Needle Types for Prostate Biopsy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
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