Clinical trials: CPR, active
Cardiac Arrest (CA)
Self-training and Resuscitation Techniques: Evaluation of the Performance and Impact on the Quality of Cardiopulmonary Resuscitation (CPR)
Cardiac arrest (CA) remains one of the leading causes of death worldwide, and its incidence continues to increase. The median survival rate following in-hospital cardiac arrest in France is 19%.
- Trial name
- ATIPIQ (NCT07820605)
- Where
- France
- Volunteers
- 265 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
CPR, Cardiac Arrest (CA)
Effect of an Educational Intervention on CPR Knowledge and Skills in Schoolchildren
This study aims to evaluate the effectiveness of a CPR intervention for children aged 7 and 8. Given the high prevalence of out-of-hospital cardiac arrests (OHCA) and the proven benefits of early CPR training, the study seeks to…
- Trial name
- NCT06929715
- Testing
- Intervention for Teaching the First Link in the Chain of Survival to 7- and 8-Year-Old Children
- Where
- Colombia
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Cardiac Arrest
Efficacy and Safety of TTM in Adults With ECPR.
Investigators hypothesize that there is a difference in the 30-day survival rate and good neurological outcome rate between two groups of cardiac arrest patients undergoing ECPR, one group receiving hypothermia and the other…
- Trial name
- TTM、ECPR (NCT06608095)
- Testing
- hypothermia group, normothermia group
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Peking University Third Hospital
Out of Hospital Cardiac Arrest, Extracorporeal Cardiopulmonary Resuscitation
Rapid Prehospital ACcess to ECPR in Prague
A prospective pilot feasibility study of prehospital ECPR in patients with refractory OHCA
- Trial name
- RACE (NCT06789978)
- Testing
- Extracorporeal cardiopulmonary resuscitation (ECPR)
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- General University Hospital, Prague
Carrying Naloxone/Narcan on Their Person or in Their Vehicle, Being Trained to Respond to an Opioid Overdose
The Feasibility of Using the PulsePoint to Facilitate Overdose Education and Naloxone Distribution
This study is a feasibility trial to assess whether, in a random sample of 180 agencies where PulsePoint is already active, revised procedures (hereinafter PulsePoint-OD) to facilitate opioid overdose and naloxone distribution…
- Trial name
- PP-OD (NCT06523985)
- Testing
- Push messages (standard), Push messages (customized)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Indiana University
Medical Condition Requiring Extracorporeal Organ Support
The University of Freiburg Medical Center Extracorporeal Organ Support Device Registry
A prospective registry collecting pseudonymized clinical and treatment data from all patients treated with extracorporeal organ support (i.e., VV ECMO, VA ECMO, ECPR, Impella, IABP, and others) on the wards of the Department of…
- Trial name
- NCT05811780
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- University Hospital Freiburg
Cardiopulmonary Arrest
REBOA in Nontraumatic OHCA
The investigators propose a multicenter randomized controlled trial in South Korea and Taiwan to observe the clinical effects of REBOA on nontraumatic out-of-hospital-cardiac-arrest (OHCA) patients.
- Trial name
- REBOA (NCT06031623)
- Testing
- REBOA
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Seoul National University Hospital
Cardiac Arrest (CA), Pediatric Cardiac Arrest (Simulated)
Augmented Reality-Cardiopulmonary Resuscitation Support for Pediatric Resuscitation
This study evaluates whether an augmented reality cardiopulmonary resuscitation feedback system (AR-CPR) can support health care providers in delivering high-quality chest compressions during pediatric cardiac arrest.
- Conditions
- Cardiac Arrest (CA), Pediatric Cardiac Arrest (Simulated), Cardiopulmonary Resuscitation (CPR)
- Trial name
- AR-CPR (NCT07778823)
- Testing
- AR-CPR
- Where
- 8 sites in United States, Canada
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cardiac Arrest, Out-Of-Hospital
Validity of ICU Clinician's Appraisal of Proportionality in CPR
The VICAP-CPR study investigates whether doctors and nurses working in Intensive Care can determine neurological outcome and future quality of life after six months in patients treated for cardiac arrest outside the hospital…
- Trial name
- VICAP-CPR (NCT07026773)
- Where
- 9 sites in Austria, Belgium and 6 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ghent
Cardiac Arrest (CA)
Hand Position, CPR Quality and Rescuer Comfort
This randomized crossover simulation study will compare two hand positions used during chest compressions: interlocked fingers and non-interlocked hands placed one on top of the other.
- Trial name
- NCT07825805
- Testing
- Interlocked-finger chest compression technique, Overlapped hands chest compression technique
- Where
- Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Cardiopulmonary Arrest, VA-ECMO
Optimized CT-imaging Protocol in VA-ECMO Patients After CPR
Veno-arterial (VA) extracorporal membrane oxygenation (ECMO) is an increasingly applied method in patients under cardiopulmonary resuscitation (CPR), who are regularly examined with a contrast-enhanced computed tomography to…
- Trial name
- NCT05290805
- Testing
- ECMO flow rate reduction
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Cardiac Arrest (CA), Cardiopulmonary Resuscitation (CPR)
The OXY-VENT Study
Effective ventilation during cardiopulmonary resuscitation is essential but can be difficult to achieve consistently. Current practice relies on visible chest rise to guide ventilation volume, although this may not always…
- Trial name
- OXY-VENT (NCT07870551)
- Testing
- Ventilation Feedback Device (Active), Control (Recording-Only)
- Where
- Netherlands
- Volunteers
- 515 people
- Sponsor
- Jeroen van Eijk
Cardiac Arrest (CA)
Does Increasing the Compression Pause From 3 to 5 Seconds in Mechanical Compression Devices Increase Ventilation Success Rate and Return of Spontaneous Circulation?
To give chest compressions during cardiopulmonary resuscitation (CPR), mechanical chest compression devices can be used. During synchronous 30:2 CPR, the standard setting on these devices leave an automated 3-second chest…
- Trial name
- LUCASVP (NCT06824961)
- Testing
- 5-second ventilation pause duration during mechanical CPR, 3-second ventilation pause duration during mechanical CPR
- Where
- 2 sites in Netherlands
- Volunteers
- 692 people
- Sponsor
- Amsterdam UMC, location VUmc
Cardiac Arrest, Ventricular Fibrillation
The OSIRIS ECPR Trial
The OSIRIS trial is an investigator-initiated, multicenter, multinational, open-label, randomized controlled trial with a 2:1 concealed allocation of refractory out-of-hospital cardiac arrest (OHCA) patients to the extracorporeal…
- Conditions
- Cardiac Arrest, Ventricular Fibrillation, Out-Of-Hospital Cardiac Arrest, Sudden Cardiac Arrest
- Trial name
- OSIRIS (NCT06805344)
- Testing
- Extracorporeal cardiopulmonary resuscitation based approach, Conventional cardiopulmonary resuscitation
- Volunteers
- 686 people
- Sponsor
- General University Hospital, Prague
Mental Health Care, Mental Health
Mental Health CPR for Cancer Survivors
This is a parallel, two-arm interventional study comparing the Mental Health CPR behavioral intervention to standard community health education.
- Conditions
- Mental Health Care, Mental Health, Depression Anxiety Disorder
- Trial name
- MH-CPR CaS (NCT07219264)
- Testing
- Mental Health CPR, Standard Community Health Education
- Where
- Puerto Rico
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Ponce Medical School Foundation, Inc.
Cardiac Death, Cardiac Arrest
Quality of Cardiopulmonary Resuscitation Pre- and Intra Hospital
The survival after intrahospital cardiac arrest has been reported to 15%. In Norway this varies between 16 and 23%.). Many factors are associated with survival after cardiac arrest, both intra- and prehospital.
- Conditions
- Cardiac Death, Cardiac Arrest, Cardiac Arrhythmia, Cardiac Disease
- Trial name
- NCT04295291
- Volunteers
- 300 people
- Sponsor
- Ostfold University College
Cardiac Arrest
RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems
RACE-CARS is a real-world cluster-randomized trial designed to evaluate a multifaceted community and health systems intervention aimed to improve outcomes of out-of-hospital cardiac arrest.
- Trial name
- NCT04660526
- Testing
- Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators, Systematic bystander resuscitation instruction by 911 operators, Comprehensive community training of lay people in CPR and AED use.
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Duke University
Healthy Participants
Effectiveness of CPR Pillow
Pillows can be used to facilitate safe and effective learning and as a cheaper and more accessible alternative to manikins or computer-based methods for CPR training by non-healthcare professionals.
- Trial name
- NCT07160881
- Testing
- Pillow maniquin training
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Cardiac Arrest (CA)
Which Position Is Better For CPR In OHCA Patients?
Use Transesophageal ultrasound in OHCA patients to identify the proper CPR position
- Trial name
- NCT07002775
- Testing
- Transesophageal ultrasound
- Where
- 2 sites in Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Hypertension Disorders in Pregnancy
Cerebroplacental Ratio (CPR) and Amniotic-Umbilical-to-Cerebral Ratio (AUCR), in in Women With Hypertensive Disorders of Pregnancy.
The primary aim of this study is to evaluate the predictive value of the Amniotic-Umbilical-to-Cerebral Ratio (AUCR) in predicting composite adverse perinatal outcomes in women with hypertensive disorders of pregnancy and to…
- Trial name
- CPR_AUCR2026 (NCT07795320)
- Volunteers
- 130 people
- Sponsor
- Assiut University