Clinical trials: Caffeine
Caffeine, Placebo
Caffeine & Bodybuilding Dehydration Ability
15-20 trained bodybuilding athletes were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design.
- Trial name
- NCT06431035
- Testing
- caffeine
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu
Panic Disorder, Healthy
Neurobehavioral Correlates of Caffeine on Anxiety, Avoidance and Interoception in Healthy Individuals and Panic Disorder.
The current study is a placebo-controlled, double-blind, randomized controlled study using a cross-over design, including Healthy Controls (HC) and participants with Panic Disorder (PD).
- Trial name
- BINCAP (NCT06145490)
- Testing
- Caffeine
- Where
- 2 sites in Sweden
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Caffeine, Placebo
Acute Caffeine Ingestion on Futsal Performance
Caffeine supplementation has been recognized such as an useful strategy for improving performance in intermittent sports, however caffeine ingestion in futsal has been barely studied.
- Trial name
- CAFFFUTSAL (NCT04852315)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Chemotherapy-induced Nausea and Vomiting
An Open Label, Single Dose, Three Part Study to Assess the Effects of Rolapitant (2 mg/mL IV Solution) on the Pharmacokinetics of Digoxin; Sulfasalazine; and the Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan in Healthy Subjects
The objective of this Open Label Study is to evaluate effects of Rolapitant IV solution, and its metabolite, on the pharmacokinetics (PK) of the P-gp substrate (digoxin), the BCRP substrate (sulfasalazine), and multiple…
- Trial name
- NCT02434861
- Testing
- Rolapitant, Digoxin, Sulfasalazine
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Tesaro, Inc.
Healthy, Elderly
The Effect of Caffeine in Elderly Citizen Following Eight Hour Abstinence From Caffeine Containing Drinks & Foods
The study investigated the effect of caffeine on physical performance in healthy citizens aged over 70 years following eight hours of abstinence from caffeine containing drinks and foods.
- Trial name
- NCT01048515
- Testing
- Caffeine
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herning Hospital
Mental Fatigue, Cognitive Performance
Phosphatidylserine, Taurine, and Caffeine for Cognitive Fatigue in Professional Football Players
This randomized, double-blind, placebo-controlled, parallel-group trial evaluated neurocognitive fatigue resistance and football-specific decision-making following 28 days of taurine-caffeine supplementation with or without…
- Conditions
- Mental Fatigue, Cognitive Performance, Athletic Performance, Soccer Performance
- Trial name
- TCPS-Foot (NCT07696052)
- Testing
- Taurine Plus Caffeine, Taurine, Caffeine, and Phosphatidylserine
- Where
- 2 sites in Poland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Vizja University in Warsaw
Caffeine, Thermoregulation
The Effects of Caffeine on Exercise Physiology and Time-trial Performance in a Hot Environment
Maintaining a stable core temperature is vital for physiological function; yet, exercise in heat can be problematic, and there is risk of exertional heat-related illness (Flouris \& Schlader, 2015; Leyk et al., 2019; Périard et…
- Trial name
- NCT07129200
- Testing
- Hot environment, Thermoneutral environment
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Caffeine
Effects Of Caffeine On Cognitive Performance
Caffeine is a potent central nervous system stimulant that increases the activity in the prefrontal cortex and can improve cognitive skills.
- Trial name
- NCT05995314
- Testing
- 3 mg/kg of caffeine, 6 mg/kg of caffeine
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Cognitively Healthy Subjects Influenced by Psychoactive Drugs
Cognitive Hyper-performance - Effects of Stimulating Substances in Chess-players
Effects of caffeine, methylphenidate, modafinil and placebo on cognitive performance of chess players in chess games and neuropsychiatric standardized tests.
- Trial name
- CHESS (NCT01834547)
- Testing
- Drugs use: methylphenidate, Drug use: modafinil, caffeine
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- K. Lieb
Healthy Volunteers
The Brain Alerting Mechanism Study
This is a study designed to look at how arousal levels in the brain change with age and how these changes influence thinking, vision, hearing and physical function in people of advanced age.
- Trial name
- NCT02050386
- Testing
- Cold pressor stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Caffeine Dependence
A Long-term Safety and Efficacy of EnXtra (E-AG-01) in Healthy Adults
The present study has been proposed to investigate the long-term safety and efficacy of EnXtra in healthy adults habituated to caffeine.
- Trial name
- NCT03731286
- Testing
- Alpinia Galanga, Microcellulose crystalline
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Caffeine, Athletic Performance
The Effects of Caffeine on Physical Performance of Ice Hockey Players
To date, only one study has evaluated the effect of caffeine supplementation on athletic performance in ice hockey players finding a lack of ergogenic effect.
- Trial name
- cafhoc (NCT05170139)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Healthy Volunteers
Testing Potential Synergistic Effects of Albuterol and Caffeine on Metabolic Rate
The purpose of this study is to define a ratio of Caffeine and albuterol that gives a synergistic increase in metabolic rate.
- Trial name
- CALM (NCT02135965)
- Testing
- 2mg of Albuterol, 4mg of Albuterol, 100mg of Caffeine
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Hemodynamic Instability, Skin and Subcutaneous Tissue Disorders
Non Invasive Measurement of the Haemodynamic Parameters and of the Advanced Glycation End Products (AGEs) Levels
The aim of this study was to investigate the difference in accumulation of AGEs (advanced glycation end-products) in the tissues of individuals who smoke in comparison with individuals who do not as well as of individuals who…
- Trial name
- NONINVASHEMO (NCT02544165)
- Testing
- caffeine intake, cigarette smoking, Caffeine intake and Cigarette smoking
- Where
- Greece
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Technological Education Institute of Sterea Ellada
Intraocular Pressure, Caffeine Dosage
The Effect of Dosage of Caffeine on Intraocular Pressure
The goal of the study is to determine the effect of different doses of caffeine on intraocular pressure. We hypothesized that higher dosage of caffeine would increase intraocular pressure more than lower doses.
- Trial name
- NCT01793311
- Testing
- decaffeinated coffee, regular dose coffee, high dose coffee
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
CYP1A2 Polymorphism, Caffeine and Resistance Training
Caffeine, CYPA12 and Resistance Training
Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance.
- Trial name
- NCT06610123
- Testing
- Caffeine and Resistance training
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Caffeine
Caffeinated Gum Softball Performance
The purpose of this study was to investigate the effects of caffeinated chewing gum on female softball pitching and hitting performance.
- Trial name
- NCT06079996
- Testing
- CAFFEINE GUM
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu