Clinical trials: Caffeine
Cognitive Performance
Effect of Phytochemicals on Aspects of Cognitive Performance
The primary purpose of the research is to test the short-term effects of the consumption of beverages containing phytochemicals and caffeine on several aspects of cognitive performance.
- Trial name
- NCT02167750
- Testing
- Cherry Flavored Beverage
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Emergence From Anesthesia
Turning Dexmedetomidine Into a Powerful Anesthetic That Can be Rapidly and Completely Reversed
In this study, the investigators will explore Atipamezole \& caffeine's ability to facilitate the emergence from anesthesia. Each subject will visit UChicago 4 times. The first time for informed consent.
- Trial name
- NCT04942340
- Testing
- Atipamezole & Caffeine, Dexmedetomidine Hydrochloride & Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Caffeine, Caffeine Withdrawal
Influence of Caffeine Consumption on the Human Circadian System
Surveys indicate that 85% of the adult population consume caffeine on a daily basis. Caffeine acts on sleep homeostatic mechanisms by antagonizing the sleep factor adenosine.
- Conditions
- Caffeine, Caffeine Withdrawal, Sleep, Circadian Rhythm
- Trial name
- CICAFF (NCT05409339)
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Psychiatric Hospital of the University of Basel
Placebo Effect
The Effect of Tablet Size on Cognitive Performance Caffeine
This study aims to assess if tablet size, due to placebo effect, alters participants' performance on cognitive tests after consuming caffeine.
- Trial name
- CaC (NCT03694886)
- Testing
- Caffeine Anhydrous with small sucrose pill, Caffeine Anhydrous with large sucrose pill
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy
Pharmacokinetic and Safety Study of Cenicriviroc and HMG-CoA Reductase Inhibitors, Caffeine and Digoxin
This is a Phase 1, Open-Label, 3-Period, Single-sequence, Drug-drug Interaction Study in Healthy Subjects to Assess the Effect of Cenicriviroc on the Pharmacokinetics (PK) of HMG-CoA Reductase Inhibitors [Rosuvastatin (ROS)…
- Trial name
- NCT02685462
- Testing
- Rosuvastatin, Atorvastatin, Simvastatin
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tobira Therapeutics, Inc.
Healty Volunteers
To Determine the Effect of KP-001 on Rosuvastatin, Caffeine PK and the Effect of Fluvoxamine on KP-001 PK in Volunteers
Part 1 will evaluate the effects of KP-001 as an inhibitor of BCRP on the PK of rosuvastatin. In the Treatment Period 1, a single dose of rosuvastatin will be administered.
- Trial name
- NCT06821698
- Testing
- KP-001, Rosuvastatin calcium10mg, Caffeine citrate
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Kaken Pharmaceutical
Exercise
A Study to See if an Energy Drink With Caffeine and Green Tea Increases Fat Burning When Exercising
The goal of this study is to evaluate the influence of consuming a drink containing a combination of caffeine and green tea extracts on fat oxidation responses at rest, during and after a period of endurance type exercise.
- Trial name
- NCT07434752
- Testing
- Active (Green tea and caffeine)
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Healthy
Caffeine, Genetic Variation and Athletic Performance
Numerous studies have investigated the effect of caffeine on athletic performance, but the findings have not been consistent. This is due, in part, to the differences in response that has been observed both within and between…
- Trial name
- GMC-AP (NCT02109783)
- Testing
- Caffeine 2mg, Caffeine 4 mg, Caffeine 0
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy, Caffeine
Effects of Variations in Caffeinated Beverages on Well-being
This study will evaluate post-beverage subjective caffeine responses and physiological responses to caffeinated beverage variations in generally healthy adults.
- Conditions
- Healthy, Caffeine, Beverage Intake
- Trial name
- NCT07404254
- Testing
- Caffeinated, low sugar beverage, Caffeinated beverage, Control beverage
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GUAYAKI SUSTAINABLE RAINFOREST PRODUCTS, INC.
Ischemia Reperfusion Injury
Does Caffeine Reduce Rosuvastatin-Induced Protection Against Ischemia-Reperfusion Injury?
Does caffeine reduce rosuvastatin induced protection against ischemia reperfusion injury?
- Trial name
- NCT00457652
- Testing
- Rosuvastatin
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Caffeine
Genetic Determinants of Cardiovascular Response to Coffee Drinking
Cardiovascular and neuropsychologic effects of coffee are still debated. The precise mechanism underlying the actions of caffeine on the cardiovascular and neuropsychologic systems is incompletely understood and a considerable…
- Trial name
- NCT01330680
- Testing
- Coffee, Decaffeinated coffee
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Healthy
Food Matrix Effect on Flavanol Absorption, Metabolism and Excretion: Methylxanthines
Dietary intervention study in healthy young adult males to evaluate concentration of flavanol metabolites in plasma and urine after single acute intakes of methylxanthines.
- Trial name
- NCT03526107
- Testing
- CF Control, CF-Theobromine, CF-Caffeine
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Climbing, Caffeine
Caffeine and Sport Climbing Performance
To determine the effects of ingesting caffeine at a dose of 3 mg/kg body mass on pull-up performance and handgrip-related measures in trained climbers.
- Trial name
- Climbing&CAF (NCT07333443)
- Testing
- Acute and moderate dose of caffeine (3 mg/kg body mass)
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Alertness
Evaluating the Impact of Energy Drink Formulas on Alertness for an Extended Period
The primary purpose of the research is to evaluate in healthy adults the time course effects of energy drink formulas containing 120 mg caffeine with varying levels of taurine and b vitamins on subjective alertness in the…
- Trial name
- NCT07400614
- Testing
- All beverages are flavor and color matched, Flavored carbonated beverage, color-matched
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Caffeine-Induced Thermogenesis, Brown Adipose Tissue Activation
Caffeine-Induced Thermogenesis Assessed by Infrared Thermography
This study evaluated thermogenic and physiological responses to 200 mg of caffeine administered following a carbohydrate gel in healthy adults.
- Trial name
- NCT07868302
- Testing
- Carbohydrate Gel, Caffeine
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istanbul Health and Technology University
Vertigo, Diseases, Vestibular
Effect of Caffeine Intake in Vestibular Function
Objective: Assess the effect of caffeine in the following vestibular function tests: Cervical Vestibular Evoked Potential (cVEMP), Ocular Vestibular Evoked Potential(oVEMP) and Caloric Test.
- Conditions
- Vertigo, Diseases, Vestibular, Caffeine
- Trial name
- NCT02825199
- Testing
- Caffeine, Non caffeine
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Instituto Brasiliense de Otorrinolaringologia
Alcohol or Other Drugs Effects
Combined Effects of Alcohol and Caffeine
The purpose of this study is to investigate the effects of caffeine on the self-administration of alcohol. The study will also examine the combined effects of alcohol and caffeine on behavioral performance, participant ratings of…
- Trial name
- NCT01289561
- Testing
- Alcohol + Caffeine Beverage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Energy Expenditure
Efficacy of ONE A DAY Weightsmart Advanced Versus Caffeine and Placebo on Energy Expenditure, Thermogenesis and Perceived Energy Levels in Women.
The study is considered research because efficacy (how well a drug works) information is needed in healthy, 25-45 year-old, female subjects with moderate caffeine intake.
- Trial name
- NCT00781586
- Testing
- One-A-Day Weight S.A. (Multi-Vitamins, BAY94-9350), Caffeine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Bayer
Exercise Performance Impairment, Cognitive Function Decline
Effects of Energy Drink on Repeated Sprint Performance and Cognitive Function in Athletes
Energy drinks are often used by athletes before competitions to enhance their performance. Recent research has pointed out that the performance effects of select ingredients have been studied individually but not in combination…
- Conditions
- Exercise Performance Impairment, Cognitive Function Decline, Fatigue
- Trial name
- NCT07104188
- Testing
- Caffeine, Energy Drink
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Chien-Wen Hou
Athletic Performance, Sports Performance
Effects of Afternoon Napping, Caffeine, and Standardised Active Recovery on Evening Athletic Performance
This study evaluated whether afternoon napping, caffeine ingestion, and a standardised active recovery and nutritional protocol could influence evening physical and cognitive performance in healthy university athletes.
- Conditions
- Athletic Performance, Sports Performance, Exercise Performance, Circadian Rhythm
- Trial name
- NAP-CAF-REC (NCT07652424)
- Testing
- Afternoon Nap, Caffeine, Standardised Active Recovery and Nutritional Protocol
- Where
- Tunisia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax