Clinical trials: Cancer Detection Rate
Serrated Polyp, Colorectal Neoplasms
Increasing Serrated Polyp Detection With a Brief Awareness Training
In this non-randomized controlled trial, a semi-random group of Dutch endoscopist receive an oral training about the significance of serrated polyps.
- Trial name
- NCT03902899
- Testing
- Educational intervention (oral presentation)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Gastroscopy Time, Early Gastric Cancer
Setting the Shortest Examination Time of Gastroscopy to Improve the Detection Rate of Upper Gastrointestinal Tumors
This multicenter, prospective, interventional study aims to include 2000 gastroscopic procedures and investigate the relationship between procedure time and lesion detection rate in tertiary endoscopic centers in China.
- Conditions
- Gastroscopy Time, Early Gastric Cancer, Detection Rate
- Trial name
- NCT04602299
- Testing
- Set the minimum time of gastroscopy
- Where
- 2 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Cancer, Polyp
Performance Evaluation of the NaviAid™ G-Eye System
The purpose of this study is to compare the additional diagnostic yield obtained by performing NaviAid™ G-Eye procedure vs. the diagnostic yield obtained by performing standard colonoscopy procedure.
- Conditions
- Colorectal Cancer, Polyp, Adenoma
- Trial name
- NCT01552200
- Testing
- Group A-Standard Colonoscopy, then NaviAid™ G-Eye procedure, Group B-NaviAid™ G-Eye procedure, then Standard Colonoscopy
- Where
- 4 sites in Germany, Israel
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Adenoma, Colorectal Cancer
Comparison of Adenoma Detection Rate With ENDOCUFF VISION® vs. G-EYE®
The study is intended to compare the detection rate obtained by performing G-EYE® high definition colonoscopy vs. the detection rate obtained by performing ECV high definition colonoscopy.
- Trial name
- NCT04708951
- Testing
- ENDOCUFF VISION® device, G-EYE® colonoscope
- Where
- 3 sites in United States, Germany
- Volunteers
- 970 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Colorectal Neoplasms
Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)
Adenoma detection rate (ADR) is a quality indicator of colonoscopy performed for colorectal cancer screening. Population studies have shown that traditional air colonoscopy fails to eliminate post screening colonoscopy cancers or…
- Trial name
- NCT01607255
- Testing
- Indigo carmine, water (exchange) method, water (exchange) plus dye method
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colorectal Cancer, Adenoma
G-Eye Advanced Colonoscopy For Increased Polyp Detection Rate-randomized Tandem Study With Different Endoscopist
The purpose of this study is to compare the adenoma detection rate of G-EYE™ high definition colonoscopy with that of standard high definition colonoscopy.
- Trial name
- NCT02066064
- Testing
- Standard Colonoscopy, G-EYE(TM) Colonoscopy
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Prostate Cancer Diagnosis
Can Needle Size Improve Cancer Detection Rate of Transperineal MRI Target Prostate Biopsy Without Affecting Side Effects?
Differences in terms of diagnostic capability and side effects related to the needle caliber used for prostate biopsy sampling in patients with suspected prostate cancer
- Trial name
- TARGET (NCT06420115)
- Testing
- different needle size for prostate biopsy
- Where
- Italy
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Adenoma Detection Rate Improvement in Screening Colonoscopy
Endoscopic Size Assessment of Advanced Adenomatous Polyps
The investigators are retrospectively comparing detection rates of adenomatous polyps, advanced adenomas, and size assessment of the polyps among Rush University Medical Center endoscopists.
- Trial name
- NCT02193646
- Where
- United States
- Volunteers
- 1,930 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Recall Rate, Cancer Detection Rate
Tomosynthesis in the Oslo Breast Cancer Screening Program
The Digital Breast Tomosynthesis (DBT) in the Oslo Mammography Screening Program will include women aged 50 to 69 years invited to the population-based mammography-screening program.
- Conditions
- Recall Rate, Cancer Detection Rate, False Positive Rate, Positive Predictive Value
- Trial name
- DBT (NCT01248546)
- Testing
- Digital breast tomosynthesis
- Where
- Norway
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Adenoma, Colo-rectal Cancer
A Dual Tandem Study - SC vs. CAD-EYE vs. CAD-EYE With G-EYE
Single-center, four-arm dual-tandem, randomized, open-label study involving the following devices: 1. The Standard Colonoscope is a high-definition colonoscope employing advanced optical filtering and enhancement techniques …
- Trial name
- NCT05318495
- Testing
- Standard Colonoscopy, CAD-EYE, G-EYE
- Where
- Germany
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Colorectal Cancer, Polyp
Safety and Efficacy of the NaviAid™ G-Eye System During Colonoscopy
To evaluate the safety of using the NaviAid™ G-Eye system during Colonoscopy
- Conditions
- Colorectal Cancer, Polyp, Adenoma
- Trial name
- NCT01749722
- Testing
- NaviAid™ G-Eye procedure
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colorectal Neoplasms, Colonic Polyp
BowelScope: Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities
This study aims to assess the effect, if any, on the adenoma detection rate of BowelScope bowel cancer screening flexible sigmoidoscopies by using the Endocuff Vision device.
- Conditions
- Colorectal Neoplasms, Colonic Polyp, Adenoma, Neoplasia GI
- Trial name
- B-ADENOMA (NCT03072472)
- Testing
- Endocuff Vision
- Where
- 16 sites in United Kingdom
- Volunteers
- 3,221 people, healthy volunteers welcome
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Adenomatous Polyps, Colorectal Polyps
Endoscopic Quality Improvement Program
Effective colorectal cancer (CRC) screening relies on early identification and removal of both polypoid and non-polypoid lesions with neoplastic potential.
- Trial name
- EQUIP (NCT01415817)
- Testing
- Training session
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Canceer
Usefulness of Endocuff in the Adenoma Detection Rate. Comparative Study
Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. The cumulative risk of developing CRC is about 6% lifelong.
- Trial name
- NCT02387593
- Testing
- ENDOCUFF
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Circulating Tumor Cell, Squamous Cell Carcinoma of the Head and Neck
CTC Detection Rate in SCCHN With a in Vivo Device
Detection rate and isolation yield of CTC is low in squamous cell carcinoma of head and neck (SCCHN) with in vitro approaches rely on limited sample volumes.
- Trial name
- NCT03071900
- Testing
- circulating tumor cell analysis
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nanjing Tongren Hospital
Early Detection of Cancer
A Questionnaire for Endoscopic Prediction Improvement of Gastrointestinal Cancer
Despite improvements in a range of chemo, radio and surgical therapies, the overall survival at 5 years from gastrointestinal cancer remains poor.
- Trial name
- NCT04071431
- Testing
- Result masking
- Where
- China
- Volunteers
- 34,906 people, healthy volunteers welcome
- Sponsor
- Yanqing Li
Colonoscopy, Safety Issues
Motorized Spiral Colonoscopy Trial: A First Feasibility Trial
The aim of this study is to assess the feasibility and the safety of the Novel Motorized Spiral Endoscope to examine the colon. The study is conceived as proof of concept trial with the primary aim to achieve a cecal intubation…
- Conditions
- Colonoscopy, Safety Issues, Adenoma
- Trial name
- MSCT (NCT03000361)
- Testing
- Motorized Spiral Colonoscopy
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Evangelisches Krankenhaus Düsseldorf
Breast Cancer
Low-dose Molecular Breast Imaging: Comparison of Breast Cancer Detection Rate at Initial Screening and Two-year Follow-up
The purpose of this research is to evaluate whether repeating a screening Molecular Breast Imaging (MBI) study two years after an initial screening MBI study further improves breast cancer detection in women with dense breast…
- Trial name
- NCT01723124
- Testing
- Molecular Breast Imaging
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Adenoma, Adenoma Colon
Impact of AI on Trainee ADR
Adenoma detection rate (ADR) is a validated quality metric for colonoscopy with higher ADR correlated with improved colorectal cancer outcomes.
- Conditions
- Adenoma, Adenoma Colon, Colorectal Cancer
- Trial name
- NCT05423964
- Testing
- AI use in Endoscopy Room, Non-AI use Standard of Care endoscopy room
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Colon Polyp, Colon Adenoma
Impact of Screen Size on Colorectal Adenoma Detection
The purpose of this study is to assess whether the use of large screen during colonoscopy will increase adenoma detection rate.
- Conditions
- Colon Polyp, Colon Adenoma, Colorectal Neoplasms
- Trial name
- NCT04749303
- Testing
- Large Screen
- Where
- Hong Kong
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong