Clinical trials: Cancer Neck
Nasopharyngeal Carcinoma
Anti-EGFR Therapy Plus IMRT Concurrent Chemoradiotherapy in Locally Advanced NPC Resistant to Induction Chemotherapy
This study is a prospective phase II trial which is designed to evaluate the efficacy and safety of IMRT combined with concurrent chemotherapy and anti-EGFR monoclonal antibody in locally advanced nasopharyngeal carcinoma with…
- Trial name
- NCT04508816
- Testing
- cetuximab (CTX) or nimotuzumab (NTZ)
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fudan University
Oral Cancer, Oropharyngeal Cancer
Speech-based AI-driven Diagnostics and Rehabilitation for Oral and Oropharyngeal Cancer.
Participants diagnosed with oral cancer, oropharyngeal cancer, or oral potentially malignant lesions, as well as healthy controls, had their speech audio recordings collected for the development and validation of AI-driven models…
- Trial name
- speech omics (NCT07347899)
- Where
- China
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Yudong Xiao
Cervical Cancer Screening
Addressing Stigma in Screening and Diagnostic Delay for Cervical Cancer
This study aims to 1) implement a culturally and contextually rooted innovative multifoci, social marketing intervention involving societal focused media campaign elements to break down the barriers and facilitate timely and…
- Trial name
- NCT01287871
- Testing
- supportive care
- Where
- United States
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Cervical Cancer, Healthy Diet
HPV Vaccination Among Daughters of Latina Immigrants
The overall goal of this study to promote HPV vaccine uptake among daughters of Latina immigrants between the ages of 9 and 12.
- Trial name
- NCT04154319
- Testing
- HPV Vaccination, Healthy Eating
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cervical Intraepithelial Neoplasia (CIN), Cervicitis
VIA Versus Colposcopy
The aim of this study is to compare the effectiveness of visual inspection with acetic acid (VIA) versus colposcopy in terms of sensitivity and specificity in diagnosis of pre-malignant cervical lesions among women, and to assess…
- Trial name
- NCT07692919
- Testing
- VIA
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Colon Cancer, Breast Cancer
Understanding the Value of Community Vital Signs in Primary Care
Social determinants of health (e.g. the income, education, and environment of patients) may exert greater influence on health outcomes than traditional clinical factors (e.g. lab results, diagnoses, and family history).
- Conditions
- Colon Cancer, Breast Cancer, Cervical Cancer, Prostate Cancer
- Trial name
- NCT02512835
- Testing
- Community vital signs
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Head and Neck Cancer, Trismus
Photobiomodulation and Sonophoresis Improving Jaw Mobility and Quality of Life Among Head and Neck Cancer Survivors
Head and neck cancer originate from the several different anatomical subsites especially the squamous cell carcinoma. This involves mainly Oropharynx, Hypopharynx, and Larynx.
- Trial name
- NCT04082793
- Testing
- Photobiomodulation therapy with mandibular exercises, Sonophoresis with mandibular exercises
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Head and Neck Cancer (H&Amp;Amp;N), Lymph Nodes
The eValuation of Sources of vIBRAtioN for Vibrational Shear Wave elasTography
Patients suffering with Head and Neck Cancer often must wait 3 months or more to know if their treatment has been effective, which can be very stressful.
- Trial name
- VIBRANT (NCT07098819)
- Testing
- Vibrational Shear wave elastography algorithm
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Institute of Cancer Research, United Kingdom
Type 2 Diabetes, Thyroid Cancer
Association Between Persistent Organic Pollutants and Type 2 Diabetes /Thyroid Cancer
Persistent organic pollutants (POPs) are a class of organic pollutants in the environment characterized by persistent, bioaccumulation, long-range transport and biological toxicity.
- Conditions
- Type 2 Diabetes, Thyroid Cancer, Organic Pollutant
- Trial name
- NCT05218395
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
Vaginal Infection, ASC-US
Probiotic Implementation as Help in Solving Vaginal Infections
Over recent years, a growing interest has developed in microbiota and in the concept of maintaining a special balance between Lactobacillus and other bacteria species in order to promote women's well-being.
- Trial name
- NCT03372395
- Testing
- Lactobacillus rhamnosus BMX 54
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Oral Squamous Cell Carcinoma
Dissecting the Heterogeneity of Oral Cancer Pain
Oral squamous cell carcinoma (SCC) produces a higher prevalence and more severe pain than all other cancers. Orofacial pain is one of the most common initial symptoms of oral cancer and often leads to the diagnosis of oral…
- Trial name
- NCT05024383
- Testing
- Chemical sensitivity, Mechanical sensitivity
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Oropharyngeal Tumor
A Study of Mucosal Sparing Proton Beam Therapy (PBT) in Resected Oropharyngeal Tumors
This study is an observational study evaluating the clinical outcomes of mucosal sparing proton beam therapy (PBT) after resection of favorable risk oropharyngeal cancer patients.
- Trial name
- NCT02736786
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Carcinogenesis, Oral Cancer
Study on the Carcinogenesis of Gα12 in Oral Cancer, and the Treatment of Oral Cancer Using Ga12 Inhibitor.
Study on the carcinogenesis of Gα12 in oral cancer, and chemopreventive possibility for the treatment of oral cancer using Ga12 inhibitor.
- Trial name
- NCT01919580
- Where
- Taiwan
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
HPV - Anogenital Human Papilloma Virus Infection
Screening for Cervical Intraepithelial Neoplasia Using Self-collected Menstrual Blood
The purpose of this study is to investigate the feasibility and efficacy of assessing HR-HPV DNA and HPV E6/E7 mRNA via self-collected menstrual blood in a smart menstrual pad.
- Trial name
- NCT03638427
- Testing
- Menstrual Blood Analysis (Menstrual Blood Analysis)
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cervical Cancer Screening
HPV Testing for Cervical Cancer Screening Study
This is a randomised controlled trial of HPV testing with cytology triage for HPV positive women compared to liquid-based cervical cytology (LBC).
- Trial name
- HPVFOCAL (NCT00461760)
- Testing
- Cervical cancer screening undertaken by HPV testing as a single primary screening test with cytology triage of women who are HPV positive
- Where
- 4 sites in Canada
- Volunteers
- 25,223 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cervical Cancer
A Novel Smart Speculum Versus a Standard Speculum for Easy Visualisation of the Cervix and Performing Remote Cervical Cancer Screening
Objective: The main objective of this study is to verify the level of comfort for patients and the degree of cervical visibility for health providers using a novel smart speculum compared to the standard speculum.
- Trial name
- NCT06359431
- Testing
- Novel Smart Speculum, Standard speculum
- Where
- Cameroon
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- GICMED
Breast Neoplasms, Endometrial Neoplasms
Chemotherapy With Whole Body Hyperthermia to Treat Resistant Breast, Endometrial, Cervical and Ovarian Cancers
Thermal therapy (hyperthermia of heat) can increase the effect of chemotherapy treatments. By itself, thermal therapy can also kill cancer cells.
- Conditions
- Breast Neoplasms, Endometrial Neoplasms, Cervix Neoplasms, Ovarian Neoplasms
- Trial name
- NCT00178802
- Testing
- thermochemotherapy (with 5-fluorouracil/interferon-a/liposomal doxorubicin)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Esophageal Cancer
Phase II Trial of Thalidomide Combined With Concurrent Chemoradiotherapy in Esophageal Cancer
The purpose of this study is to down-regulate VEGF expression in esophageal cancer patients by thalidomide, so to improve their chemoradiotherapy effect.
- Trial name
- NCT01551641
- Testing
- chemoradiotherapy, thalidomide, without thalidomide
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Changzhou No.2 People's Hospital
Nasopharyngeal Carcinoma
S-1 Combined With IMRT Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma
This study is a prospective phase II trial which is designed to evaluate the efficacy and safety of IMRT combined with S-1 CCRT for locally advanced NPC.
- Trial name
- NCT03668366
- Testing
- S-1
- Where
- China
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Fudan University
Cervical Cancer, High Grade Sil
Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women.
Nearly 8 000 new cervical cancer cases are diagnosed in South Africa per year; many are still undiagnosed and about 50% of diagnosed cases succumb per year.
- Conditions
- Cervical Cancer, High Grade Sil, CIN2
- Trial name
- DiaVACCS (NCT02956031)
- Testing
- Screening, Colposcopy, LLETZ
- Where
- South Africa
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Pretoria
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