Clinical trials: Cancer of Colon
Colorectal Cancer
Effectiveness of Decision-aid Video on Colorectal Cancer Screening
Colorectal cancer (CRC) is the second most common cancer in Malaysia. Diagnosing CRC at early stage is crucial to reduce their mortality risk. To achieve this aim, CRC screening promotion intervention is deemed necessary.
- Trial name
- DAVOCS (NCT04692987)
- Testing
- Decision-aid video
- Where
- Malaysia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Body Mass Index 25 or Greater, BRCA1 Gene Mutation
Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members
This pilot clinical trial studies different types of energy balance interventions to see how well they work in increasing the physical activity levels of breast cancer gene-positive patients, Lynch syndrome-positive patients…
- Conditions
- Body Mass Index 25 or Greater, BRCA1 Gene Mutation, BRCA2 Gene Mutation, Breast Carcinoma
- Trial name
- NCT02194387
- Testing
- Dietary Intervention, Internet-Based Intervention, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Adenoma, Colorectal Cancer
Early Screening of Colorectal Cancer Based on Plasma Multi-omics Combining With Artificial Intelligence
To evaluate the accuracy and effectiveness of a novel screening method based on plasma multi-omics combining with artificial intelligence in a large prospective cohort for the detection of colorectal cancer and advanced adenomas.
- Trial name
- RECOMMEND (NCT05587452)
- Testing
- Colonoscopy, Test of ctDNA methylation, Test of characteristics of ctDNA fragment
- Where
- 5 sites in China
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Colorectal Cancer
Vitamin D, Genes and Colorectal Cancer
The aim of this study is to investigate the interaction between intake of vitamin D and polymorphisms in GC and CYP2R1 in relation to risk of colorectal cancer in a Danish prospective cohort study.
- Trial name
- NCT03370432
- Testing
- Observational
- Volunteers
- 2,895 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Colo-rectal Cancer
EXercise And Colo-Rectal Cancer Trial
The aim of this study is to assess the feasibility and effectiveness of a home-based walking and strengthening intervention on physiological, biochemical and psychological outcomes in colo-rectal cancer survivors.
- Trial name
- EXACT (NCT02607787)
- Testing
- Exercise, Control
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Decision Aid
Using Visual Arrays to Support Understanding of Genetic Risk
The goal of this study is to understand how people understand risk from genetic testing. The investigators want to understand what visual aid best helps people accurately assess risk.
- Trial name
- NCT06994832
- Testing
- Visual Array, Narrative Visual Array, Choice
- Where
- United States
- Volunteers
- 1,045 people, healthy volunteers welcome
- Sponsor
- Stephanie B. Seminara, MD
Sessile Serrated Adenoma, Colorectal Polyp
Assessing the Agreement Between Endoscopic and Histopathological Diagnosis of Colorectal Sessile Serrated Lesions.
The goal of this observational study was to assess the degree of agreement between the endoscopic and anatomopathological diagnosis of sessile serrated colorectal lesions in adult patients undergoing colonoscopy in Hospital…
- Conditions
- Sessile Serrated Adenoma, Colorectal Polyp, Adenoma Colon, Colorectal Cancer
- Trial name
- NCT06173297
- Where
- Brazil
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- Hospital Sirio-Libanes
Colorectal Cancer, Polyps
Clinical Validation of Stool DNA-based SDC2 Methylation Test for Colorectal Cancer Detection
Pivotal trials of SDC2 methylation biomarker test in stool DNA to estimate clinical sensitivity and specificity in detection of colorectal cancer.
- Conditions
- Colorectal Cancer, Polyps, Other Cancers, Healthy
- Trial name
- NCT03146520
- Testing
- EarlyTect Colon Cancer
- Where
- South Korea
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- Genomictree, Inc.
Colorectal Cancer, Adenomatous Colorectal Polyps
Selenium for Prevention of Adenomatous Colorectal Polyps
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. Selenium may be effective in preventing the recurrence of adenomatous colorectal polyps.
- Conditions
- Colorectal Cancer, Adenomatous Colorectal Polyps, Precancerous Condition
- Trial name
- NCT00078897
- Testing
- Selenium
- Where
- 7 sites in United States
- Volunteers
- 1,621 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Colorectal Adenoma, Colorectal Polyp
To Compare Artificial Intelligence Software Aided Adenoma Detection in Screening Colonoscopies Versus Standard Colonoscopy Without Artificial Intelligence Software Assistance in Participants Between 45 and 75 Years of Age
The aim of this study is to assess the efficacy of Ultivision Artificial Intelligence (AI) Software in detecting adenomas in screening colonoscopy procedures. The safety of Ultivision AI Software will also be assessed.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colorectal Adenocarcinoma, Colorectal SSA
- Trial name
- AIDA (NCT04196088)
- Testing
- Ultivision Artificial Intelligence Software, No Artificial Intelligence Software enhancement
- Where
- 9 sites in United States
- Volunteers
- 978 people, healthy volunteers welcome
- Sponsor
- Docbot, Inc.
Colorectal Cancer
Exploratory Analysis on the Impact of Morbidities on Colorectal Cancer Screening Uptake
The primary aim of this project is to examine the association between having a long-term condition (morbidity) and screening uptake for colorectal cancer.
- Trial name
- NCT02503969
- Testing
- Exposure to having a long-term condition.
- Where
- United Kingdom
- Volunteers
- 8,776 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Colon Cancer
A Prospective Study of a New Immunochemical Fecal Occult Blood Test in U.S. Veteran Patients Undergoing Colonoscopy
The purpose of our study is to evaluate the diagnostic validity of a new immunofecal occult blood test (IFOBT) (Teco Diagnostics) in U.S. veterans and to compare it with the guaiac based FOBT.
- Trial name
- NCT00533975
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breast Cancer, Prostate Cancer
Redes III Patient Navigator Qol Study
This proposed 5-year Redes En Acción research study involves a mixed-methods approach that occurs in two phases across two distinct and diverse HL communities.
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer
- Trial name
- NCT02275754
- Testing
- PN+LCNC, PN Only
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Colo-rectal Cancer
Role of Programmed Death Ligand 1 in Colorectal Cancer
1. - Evaluation of diagnostic importance of soluble programmed death ligand-1 in patient with recently diagnosed as Colorectal cancer at different stages of disease . 2.
- Trial name
- SPDL1 (NCT07088341)
- Testing
- elisa
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Colo-rectal Cancer, Colonic Neoplasms
Effect of Adding Simethicone to Split-dose Polyethylene Glycol for Bowel Preparation in a Screening Colonoscopy Setting
Colonoscopy is currently accepted as the gold standard in screening, surveillance and prevention for colorectal cancer (CRC), and therefore, its quality is a major priority.
- Trial name
- NCT03816774
- Testing
- PEG split-dose and simethicone
- Where
- Portugal
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Colorectal Neoplasms
Study of Folic Acid, Calcium and Vitamin D in Preventing Colorectal Polyps and Colorectal Cancer
Folic acid (FA) and its derivatives (folate) which play a role in nucleotide synthesis and methylation reactions as well as calcium and vitamin D are assumed to be effective in the prevention of colorectal polyps and Colorectal…
- Trial name
- NCT02066688
- Testing
- folic acid, folic acid calcium vitamin D3, calcium
- Where
- China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Colorectal Cancer Control and Prevention
Life Expectancy-informed Colorectal Cancer Screening
The purpose of this study is to improve life-expectancy concordant colorectal cancer screening for adults over 75 years through design and testing of a life expectancy notification to clinicians delivered via the electronic…
- Trial name
- CRC (NCT07141901)
- Testing
- Decision Tool
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Kathryn Martinez
Colonic Polyp, Colonic Neoplasms
Validation of Aer-O-Scope Colonoscope System Cecal Intubation
61 subjects (male or female) between the ages of 45 and 75 will undergo colonoscopy. The primary outcome is Cecal Intubation
- Conditions
- Colonic Polyp, Colonic Neoplasms, Colonic Diseases, Colon Adenoma
- Trial name
- NCT03949777
- Testing
- Aer-O-Scope Colonoscopy
- Where
- Israel
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- GI View Ltd.
Colon Cancer
Latino Peers as Patient Navigators for Colon Cancer Screening
Disparities among racial and ethnic minorities remain prevalent despite advances in medical science that make thes early detection and prevention of colorectal cancer a possibility for all human kind.
- Trial name
- NCT02226107
- Testing
- Peer-PN, Pro-PN
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colon Cancer
Reminding Patients of the Important of Colorectal Cancer Screening Results in Patient-Initiated Promoting Colorectal Cancer Screening Via Colonoscopy
Colorectal cancer is the third most common cancer diagnosed and third leading cause of cancer-related deaths in the United States for both men and women.
- Trial name
- NCT01526239
- Testing
- Colorectal cancer screening pamphlet
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma