Clinical trials: Cardiac Ischemia
CAD
Aspirin Responsiveness in Women With Coronary Artery Disease
The purpose of this study is to measure the percentage of women with known Coronary Artery Disease (CAD) who are hyporesponsive to low dose (81 mg) aspirin.
- Trial name
- NCT01406990
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Creighton University
Ventricular Tachycardia, Ischemic Cardiomyopathy
SMART Identification of Ventricular Tachycardia Isthmus
Context : Ventricular tachycardia (VT) are serious heart rhythm disorders which can lead to sudden death. A curative treatment for these abnormalities in the cardiac electrical conduction system is possible through an…
- Trial name
- SMARTIS (NCT04852497)
- Testing
- Ventricular tachycardia ablation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Central Hospital, Nancy, France
Atrial Fibrillation
Effect of Ischemic Preconditioning on Atrial Fibrillation After Electrocardioversion
Remote ischemic preconditioning is one way to influence the success of therapy in cardiovascular patients. By means of remote ischemic preconditioning the incidence of atrial fibrillation after cardiac surgery was reduced by 54%.
- Trial name
- PRECON-AF (NCT05342220)
- Testing
- Remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- St. Josefs-Hospital Wiesbaden GmbH
Heart Failure, Left Bundle-Branch Block
Left Bundle Branch Pacing on Outcomes and Ventricular Remodeling in Biventricular CRT Nonresponders
Heart failure (HF) is the most common nosology encountered in clinical practice. Its incidence and prevalence increase exponentially with increasing age and it is associated with the increased mortality, more frequent…
- Conditions
- Heart Failure, Left Bundle-Branch Block, Ischemic Cardiomyopathy, Non-ischemic Dilated Cardiomyopathy
- Trial name
- RESCUE (NCT05760924)
- Testing
- Cardiac Resynchronization Therapy Devices with Defibrillator Function (CRT-D) or CRT-D Leads Replacement, CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right and Left Ventricular Pacing, CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right Ventricular Pacing
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Coronary Stenosis
HOW To Optimally Implant BioResorbable Scaffold - Intravascular Imaging Versus Quantitative Coronary Angiography Guidance
The objective of this trial is to compare clinical outcomes between imaging-guided and QCA-guided strategy in patients with native coronary artery disease undergoing BRS implantation.
- Trial name
- HOWTO-BRS (NCT03175523)
- Testing
- quantitative coronary angiography guided Bioresorbable scaffold implantation, imaging guided Bioresorbable scaffold implantation
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seung-Jung Park
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG)
Examining the Effects of Video-Assisted Discharge Education After Coronary Artery Bypass Graft Surgery on Patient Satisfaction and Anxiety
This study was conducted to examine the effects of standard and individualized video-assisted discharge education on patient satisfaction and anxiety levels following Coronary Artery Bypass Graft (CABG) surgery.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG), Postoperative Discharge Education
- Trial name
- NCT07528859
- Testing
- video discharge education, individual video discharge training, discharge education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Ischemic Heart Disease
A Clinical Study of Evaluating Myocardial Viability in Ischemic Heart Disease with Integrated 18F-FDG PET/MR
The main purpose is to evaluate the accuracy of myocardial imaging obtained through integrated 18F-FDG PET/MR in detecting viable myocardium.
- Trial name
- NCT06712862
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai East Hospital
Acute Coronary Syndrome, Acute Coronary Syndrome With Renal Dysfunction
Latent TGF-β-binding Proteins Affect the Fibrotic Process in Renal Impairment and Cardiac Dysfunction
The project is planed to explore the impact of LTBP4 and other matrix protein and potentially related biomarkers on renal outcomes, cardiac outcomes and all-cause mortality in patients with suspected acute coronary syndrome (ACS).
- Trial name
- NCT04998227
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
ST Elevation Myocardial Infarction (STEMI), Malondialdehyde
Curcumin-Piperine Supplementation in STEMI - SPICE STEMI Trial
This study aims to evaluate whether supplementation with a combination of curcumin and piperine can help reduce inflammation and oxidative stress in patients who have experienced a heart attack called ST-Elevation Myocardial…
- Conditions
- ST Elevation Myocardial Infarction (STEMI), Malondialdehyde, Hs-CRP, Curcumin
- Trial name
- SPICE STEMI (NCT07149961)
- Testing
- Curcumin plus Piperine
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Diponegoro
Myocardial Reperfusion Injury, Cytoprotection
The Protective Effects Of Treatment With Hyperbaric Oxygen Prior To Bypass Heart Surgery
The purpose of this study was to determine if treating patients who have coronary heart disease with hyperbaric oxygen (HBO) prior to coronary artery bypass graft (CABG) surgery reduces injury to the heart and vascular system…
- Trial name
- NCT00623142
- Testing
- Hyperbaric Oxygen
- Where
- United Kingdom
- Volunteers
- 81 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Psoriasis, Cardiovascular Diseases
Prevalence and Risk Factors asSOciated With CArdiac comorbiDIty in psoriAsis
In a prospective cohort study (n = 1.000), the investigators aim to investigate the correlation between cardiac biomarkers and advanced echocardiography and determine whether these are prognostic markers of heart disease in…
- Conditions
- Psoriasis, Cardiovascular Diseases, Cardiovascular Risk Factor, Cardiovascular Pathology
- Trial name
- PSOCADIA (NCT04950218)
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Herlev and Gentofte Hospital
Myocardial Bridge
Myocardial Bridge Evaluation Towards Personalised Medicine: the RIALTO Registry
Myocardial bridge (MB) is a congenital anomaly of epicardial circulation characterized by an intramural course of a coronary segment.
- Trial name
- RIALTO (NCT05111418)
- Where
- 5 sites in Italy
- Volunteers
- 444 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
STEMI
Effectiveness Evaluation in Thrombus Aspiration in Patients With STEMI and High Thrombotic Load
This study intends to evaluate thrombus on the basis of different methods for evaluating thrombus load The effect of aspiration on the prognosis of STEMI patients with high thrombotic load Provide a basis for the standardized use…
- Trial name
- NCT05043597
- Testing
- Thrombus aspiration
- Where
- China
- Volunteers
- 3,838 people
- Sponsor
- Shenzhen People's Hospital
Cardiovascular Diseases, Kidney Transplant; Complications
Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation
Cardiovascular disease (for example, heart attack, stroke, heart failure) is the commonest complication of kidney failure. Kidney transplantation reduces cardiovascular risk but cardiovascular disease remains the commonest cause…
- Trial name
- CRAFT-CTCA (NCT06234410)
- Testing
- Computed tomography coronary angiography (CTCA)
- Where
- 2 sites in United Kingdom
- Volunteers
- 332 people
- Sponsor
- University of Edinburgh
Type2 Diabetes, Heart Failure
Meta-analysis of Fish Oil Supplementation and Cardiovascular Outcomes in Diabetes
Fish oil contains a large amount of long-chain omega-3 polyunsaturated fatty acids, which are considered an important component of a healthy diet.
- Conditions
- Type2 Diabetes, Heart Failure, Myocardial Infarction, Stroke
- Trial name
- NCT04327713
- Testing
- fish oil supplement
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Percutaneous Coronary Intervention (PCI), Coronary Artery Disease
A Prospective, Multicenter, Blinded, Randomized Controlled Clinical Trial to Evaluate the Safety and Efficacy of IVUS Console and IVUS Catheter in Coronary Intervention Procedures
The goal of this clinical trial is to evaluate the safety and efficacy of IVUS Console and IVUS Catheter in coronary intervention therapy Participants will: Undergo IVUS examinations from two different manufacturers（from Pulse…
- Trial name
- IVUS (NCT06974760)
- Testing
- IVUS
- Where
- 4 sites in China
- Volunteers
- 150 people
- Sponsor
- Pulse Medical Imaging Technology (Shanghai) Co., Ltd
Myocardial Infarction, Acute
Mechanocardiography in Patients With STEMI
The study aim is to evaluate the capability of mechanocardiography in detecting acute myocardial ischemia in patients suffering evolving ST-segment elevation infarction.
- Trial name
- MECHANO-STEMI (NCT03441724)
- Testing
- Mechanocardiography
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Turku
Acute Coronary Syndromes, Geriatric Patients
Prognostic Importance of Physical Activity in Geriatric Patients With Acute Coronary Syndrome
This observational study evaluated the relationship between physical activity level and prognosis in geriatric patients admitted to the emergency department with acute coronary syndrome (ACS).
- Conditions
- Acute Coronary Syndromes, Geriatric Patients, Physical Activity Levels
- Trial name
- NCT07203924
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people
- Sponsor
- Balikesir University
Stable Angina
Impact of Spiroergometer Parameters as Diagnostic Marker of Cardiac Ischemia in Pts. With Stable Angina Compared to FFR.
In Patients with stable Angina pectoris CCS 1-3 exercise testing for ischemia detection is widely used despite the known limitations. Measurement of the FFR is invasive but gold standard for Ischemia detection.
- Trial name
- ADVANCE (NCT04450459)
- Testing
- ergospirometer test
- Where
- Germany
- Volunteers
- 121 people
- Sponsor
- Jena University Hospital
COVID, Acute Coronary Syndrome
Cardiovascular Complications and COVID-19 (CovCardioVasc-Study)
Patients with COVID-19 in the Intensive Care Unit (ICU) or hospitalized with severe form have a poor prognosis (almost 30% rate of death).
- Conditions
- COVID, Acute Coronary Syndrome, Myocardial Infarction, Myocarditis
- Trial name
- CovCardioVasc (NCT04335162)
- Where
- 8 sites in France
- Volunteers
- 198 people
- Sponsor
- Centre Hospitalier Universitaire de Nice