Clinical trials: Cardiopulmonary Diseases
Pulmonary Hypertension, Lung Disease
Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide
The purpose of this program is to evaluate the logistic issues and patient requirements for chronic pulsed INOmax delivery in ambulatory, home-care patients.
- Conditions
- Pulmonary Hypertension, Lung Disease, Sickle Cell Disease, Cardiac Transplant
- Trial name
- NCT00041574
- Testing
- Inhaled Nitric Oxide
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Mallinckrodt
Stereotype-threat, COVID-19
Stereotype Threat Effect on CPR Performance in Covid-19 Intensive Care Units: A Randomised Controlled Mannequin Study
Stereotype threat (ST) is an important issue that has been studied repeatedly in the psychology literature. ST is the thought that a person will be negatively evaluated and judged regarding a negative stereotype that belongs to…
- Trial name
- NCT05074446
- Testing
- stereotype threat manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Out-of-hospital Cardiac Arrest (OHCA), Cardiac Arrest (CA)
the Effectiveness of Continuous Compression-synchronous Ventilation (Bio-CPR)
Bio-CPR is an innovative new mechanical resuscitation model proposed by our research group. A multi-center RCT study was established to comprehensively evaluate the efficacy of this model and the current standard CPR protocol…
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), Cardiac Arrest (CA), CPR, ACLS
- Trial name
- Bio-CPR (NCT07258823)
- Testing
- CPR
- Volunteers
- 408 people
- Sponsor
- Guangdong Provincial People's Hospital
Acute Kidney Injury
Nitrite Infusion in High Risk Patients Undergoing Cardiopulmonary Bypass
The main objective of this study is to evaluate the efficacy of intravenous sodium nitrite compared with placebo in reducing the occurrence of CSA-AK as diagnosed by KDIGO criteria during the first 72 hrs after cardiac surgery in…
- Trial name
- NCT03331146
- Testing
- Saline, Sodium Nitrite
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cardiac Arrest
Effect of Pre-imaging on Cardiopulmonary Resuscitation (CPR) Pause
Patients presenting following out of hospital cardiac arrest will undergo bedside ultrasound as per the hospital clinical practice.
- Trial name
- NCT04248985
- Testing
- Pre-Imaging - an ultrasound technique of acquiring images
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Massachusetts, Worcester
Congenital Heart Disease
Angiotensin Converting Enzyme Inhibitors During Cardiopulmonary Bypass in Infants and Children
The purpose of this study is to determine whether ACE inhibitors alter the fibrinolytic, inflammatory, and hemodynamic response to cardiopulmonary bypass in infants and children with congenital heart disease.
- Trial name
- NCT00848250
- Testing
- Angiotensin Converting Enzyme Inhibitor, No ACE Inhibitor
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Vanderbilt University Medical Center
Inhospital Cardiac Arrest
Neurological Outcomes After In-Hospital Cardiac Arrest
Little is known about the long-term neurological outcomes after in-hospital cardiac arrest (IHCA). It is also not known whether withdrawal of life-sustaining measures will influence rates of survivors with poor neurological…
- Trial name
- NO-IHCA (NCT03006484)
- Testing
- No intervention
- Where
- South Korea
- Volunteers
- 322 people
- Sponsor
- Asan Medical Center
Atrial Septal Defect, Ventricular Septal Defects
Comparison of Dynamic Compliance and Airway Resistance in Pressure-Controlled Versus Volume-Controlled Ventilation in Children Undergoing Corrective Heart Surgery
The goal of this clinical trial was to compare two settings on a breathing machine used during heart surgery in children. The children in this study were born with a hole inside the heart.
- Conditions
- Atrial Septal Defect, Ventricular Septal Defects, Pulmonary Hypertension, Intracardiac and Septal Defects
- Trial name
- NCT07754591
- Testing
- Pressure Controlled Ventilation, Volume Controlled Ventilation
- Where
- India
- Volunteers
- 72 people
- Sponsor
- Nilratan Sircar Medical College
MACE, Cardiac Death
Real-World Cohort Study of Cardiopulmonary Function in Chinese Patients With Cardiovascular Disease: CPET Evaluation and Five-Year Prognostic Follow-Up Based on a Multicenter Structured Data Platform
The goal of this observational study is to observe the characteristics of cardiopulmonary exercise testing (CPET) parameters in patients across different cardiovascular diseases and to evaluate the predictive value of…
- Conditions
- MACE, Cardiac Death, Unplanned Repeat Revascularization, Cardiac Rehospitalization
- Trial name
- China-CPET (NCT07130968)
- Where
- China
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Cardiovascular Diseases, Heart Diseases
Citrulline for Children Undergoing Cardiopulmonary Bypass Surgery
This study will determine the pharmacokinetics and safety of intravenous citrulline given to children undergoing cardiopulmonary bypass for the correction of congenital heart defects.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Heart Defects, Congenital
- Trial name
- NCT00201214
- Testing
- Citrulline
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Vanderbilt University
Cardiopulmonary Arrest
Learning Curve of VL for Intubation During CPR
This is a clinical study based on analysis of video-clip data of endotracheal intubation (ETI) using videolaryngoscope (VL) and clinical data for cardiopulmonary resuscitation patients between 2012.03.01.-2015.02.28.
- Trial name
- NCT04114721
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Konkuk University Medical Center
Myocardial Infarction, Cardiopulmonary Disease
The Effect of HIIT, MICT in Patients With Myocardial Infarction
This study will investigate the effect of a 12-weeks cardiac rehabilitation training (HIIT, MICT) program on VO2peak and cardiac fibrosis in patients, and evaluate the effects of HIIT on endothelial function, microvascular…
- Conditions
- Myocardial Infarction, Cardiopulmonary Disease, Training Group, Sensitivity
- Trial name
- NCT04863677
- Testing
- High Intensity Interval Training(HIIT）, Moderate Intensity Continuous Training(MICT）
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Guangdong Provincial People's Hospital
Coronary Artery Disease, Aortic Valve Disease
Comparison of Priming Constituents in Patients Undergoing CPB Assisted Cardiac Surgery: HES 130/0.4 or Albumin 5%
The purpose of the study is to determine which priming fluid is the safest for use for priming the heart-lung machine used during cardiopulmonary bypass for patients undergoing cardiac surgery.
- Conditions
- Coronary Artery Disease, Aortic Valve Disease, Mitral Valve Disease
- Trial name
- NCT01849757
- Testing
- prime crystalloid, Human Albumin, Voluven
- Where
- Canada
- Sponsor
- University of Saskatchewan
Exercise Capacity
Cocoa Flavanols and Exercise Capacity
The purpose of this study is to characterize the potential improvement of cocoa flavanols on exercise capacity in highly trained cyclist.
- Trial name
- NCT01259739
- Testing
- Cocoa
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Obesity, Morbid, Hypertension
Comparison of Extremely Obese Patients Undergoing Gastric Sleeve Surgery
By the comparison of the preoperative and postoperative data of approximately 160 patients undergoing gastric sleeve surgery, we try to draw conclusions about the effectiveness of gastric sleeve surgery, expected complication…
- Conditions
- Obesity, Morbid, Hypertension, Diabetes Mellitus, Type 2
- Trial name
- NCT05929170
- Where
- Hungary
- Volunteers
- 160 people
- Sponsor
- University of Pecs
Cardiovascular Diseases, Cardiopulmonary Arrest
The Effect of Web-Based Gamification Applications on Nursing Students' Learning Regarding Cardiopulmonary Resuscitation
In this study, the aim was to determine students' level of knowledge regarding cardiopulmonary resuscitation by using web-based gamification applications in nursing education, and additionally, to evaluate the secondary effects…
- Conditions
- Cardiovascular Diseases, Cardiopulmonary Arrest, Web-based Gamification
- Trial name
- NCT07689422
- Testing
- web-based gamification application
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Cardiopulmonary Bypass, Obesity
Optimal Cardiopulmonary Bypass and Anticoagulation Management Strategies in Obese Patients Undergoing Cardiac Surgery
Standard Heparin management, based on total body weight, is not well established for obese patients undergoing cardiac surgery with cardiopulmonary bypass (CPB).
- Trial name
- NCT03302195
- Testing
- Heparin, cardiopulmonary bypass pump flow rate
- Where
- Canada
- Volunteers
- 410 people
- Sponsor
- Laval University
COVID-19, Cardiopulmonary Disease
Comparing Inpatient COVID-19 Outcomes in 2 Different PT Dosing Groups
The objective of this study is to compare the effects of twice-a-day 15-minute sessions of inpatient physical therapy (PT) to the standard daily 30 minute sessions.
- Conditions
- COVID-19, Cardiopulmonary Disease, Weakness, Muscle, Hypoxia
- Trial name
- CCPT (NCT04844307)
- Testing
- Shorter duration higher frequency PT, Standard PT
- Sponsor
- Montefiore Medical Center
Cardiopulmonary Arrest With Successful Resuscitation, ACS - Acute Coronary Syndrome
Add-on Cangrelor in STEMI-triggered Cardiac Arrest
In patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary angioplasty (PCI) P2Y12 receptor (P2Y12r) inhibition should be achieved as soon as possible.
- Conditions
- Cardiopulmonary Arrest With Successful Resuscitation, ACS - Acute Coronary Syndrome, Hypothermia, Induced
- Trial name
- NCT03273075
- Testing
- Cangrelor, Prasugrel, Ticagrelor
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Out-Of-Hospital Cardiac Arrest
Silesian Registry of Out-of-Hospital Cardiac Arrests
Silesian Registry of Out-of-Hospital Cardiac Arrests (SIL-OHCA) which is an initiative of the Voivodeship Rescue Service in Katowice in cooperation with the Silesian Center for Heart Diseases in Zabrze is a prospective…
- Trial name
- SIL-OHCA (NCT03654859)
- Testing
- cardiopulmonary resuscitation
- Where
- Poland
- Volunteers
- 1,560 people
- Sponsor
- Silesian Centre for Heart Diseases
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