Clinical trials: Cardiopulmonary Resuscitations
ExtraCorporeal Membrane Oxygenation (ECMO), Cardiac Arrest
Plasma Biomarkers and Platelet Morphology of Extracorporeal CardioPulmonary Resuscitation
Extracorporeal cardiopulmonary resuscitation (ECPR) constitutes a pivotal emergency intervention for cardiac arrest (CA) patients.
- Trial name
- ECPR (NCT07113769)
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Central China Fuwai Hospital of Zhengzhou University
Echocardiography, Transesophageal, In-hospital Cardiac Arrest
RescueTEE for In-hospital Cardiac Arrest (ReTEECA Trial)
ReTEECA Trial. Rescue TransEsophageal Echocardiography for In-Hospital Cardiac Arrest. This trial is aimed at studying the utility and interventional outcomes of rescue transesophageal echocardiography (RescueTEE) to aid in…
- Conditions
- Echocardiography, Transesophageal, In-hospital Cardiac Arrest, Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation
- Trial name
- ReTEECA (NCT04220619)
- Testing
- Tranesophageal Echocardiography
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cardiac Arrest, Out-Of-Hospital
Gathering Evidence on Best Practices for Lay Rescuer CPR Training
The goal of this prospective trial is to compare CPR skill and attitudes in lay rescuers. The main question[s] it aims to answer are: What is the optimal training timing, duration, and frequency for lay rescuers that leads to CPR…
- Trial name
- NCT05908500
- Testing
- CPR Training, CPR Manikin Type
- Where
- United States
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
Cardiopulmonary Resuscitation, Hand Position
Optimum Hand Position During Cardiopulmonary Resuscitation
The almost evidences of the optimal hand position during compression had been based on chest computed tomography (CT) or chest plain films of patients for investigating the effective location for compressing the left ventricle of…
- Trial name
- NCT02715180
- Testing
- low dose chest computed tomography
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Cardiac Arrest, Sudden
Impact of the Organization of the First Responders in the Remote Areas on Cardiac Arrest Victim Survival
Emergency medical services (EMS) provide emergency care not only in the urban but also in the remote areas which could be up to 40 minutes from the EMS station.
- Trial name
- NCT04485390
- Testing
- Basic life support witn use of an AED before EMS
- Volunteers
- 150 people
- Sponsor
- University Medical Centre Maribor
Cardiac Arrest
Improving the Quality of Cardiopulmonary Resuscitation (CPR) During Pediatric Cardiac Arrest
Our project aims to improve the delivery and assessment of cardiopulmonary resuscitation (CPR) during pediatric cardiac arrest by introducing 2 novel approaches: 1.
- Trial name
- QCPR (NCT02075450)
- Testing
- CPRcard, Just in Time Video
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
To Evaluate the Impact of a Basic Resuscitation Training Program on the Related Knowledge and Practices of CPR Among Private Home Nurses in Qatar
Impact of VAK & Kolb-Based Education on CPR Knowledge & Skills Among Private Home Nurses in Qatar
Out-of-hospital cardiac arrest (OHCA) is a significant global health challenge, responsible for a substantial proportion of deaths worldwide.
- Trial name
- NCT06865690
- Testing
- Eductional training program
- Where
- Qatar
- Volunteers
- 134 people
- Sponsor
- Assiut University
Heart Arrest, Seizures
Prompt Diagnosis and Treatment of Subclinical Seizures After Cardiac Arrest
Non-convulsive seizures (NCS) following cardiac arrest are common and are associated with worse neurologic outcomes and increased mortality. More prolonged seizures (status epilepticus) are associated with worse outcomes.
- Trial name
- NCT02458820
- Testing
- DSA EEG
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Children's Hospital of Philadelphia
Out-of-Hospital Cardiac Arrest
REBOA in Out-of-hospital Cardiac Arrest
Unexpected cardiac arrest is a frequent and devastating event with a high mortality and morbidity. Half of the patients who survive to ICU admission ultimately die because of hypoxic-ischemic encephalopathy.
- Trial name
- NCT04373122
- Testing
- REBOA
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Neonatal Resuscitation, Airway Management
Success of Laryngeal Mask Airway (LMA) Insertion During Continuous Chest Compressions in Neonatal Resuscitation: A Randomized Crossover Simulation Study
The purpose of this study is to evaluate the time required for laryngeal mask airway (LMA) insertion, first-attempt success rates, and airway sealing quality (air leak) during neonatal resuscitation with and without interrupting…
- Conditions
- Neonatal Resuscitation, Airway Management, Asphyxia Neonatorum, Cardiopulmonary Resuscitation (CPR)
- Trial name
- NCT07681960
- Testing
- Size 1 ProSeal™ LMA
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Cardiac Arrest, Cardiopulmonary Arrest
Use of a Feedback Device to Limit Too Shallow Compressions Associated With the Use of an I-gel® Device
Airway management in out-of-hospital cardiac arrest is still debated. Several options exist: bag-valve-mask ventilation, supraglottic devices and endotracheal intubation.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Resuscitation, Emergency Medicine
- Trial name
- NCT05709613
- Testing
- Use of a chest compressions' feedback device
- Where
- 4 sites in Switzerland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
CPR Quality Assessment
Effectiveness of Chest Compressions With Standard vs Feedback-Assisted CPR
The objective of this educational clinical trial is to compare auditory (metronome) and audiovisual (TrueCPR) feedback systems with both standard CPR and with each other in a simulated environment, focusing on their effects on…
- Trial name
- NCT07029724
- Testing
- TrueCPR Multisensory Feedback Device, Ambu Smartman ALS Pro+ (AW301) Simulation Manikin, Metronome
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Betül Akbuğa Özel
Cardiopulmonary Arrest, Pediatric ALL
Impact of a mHealth Supportive Tool on Cardiopulmonary Resuscitation' Situational Awareness
This study will be a prospective, single-center, randomized controlled trial in a tertiary pediatric emergency department with two parallel groups of voluntary pediatric physicians and nurses.
- Conditions
- Cardiopulmonary Arrest, Pediatric ALL, Resuscitation
- Trial name
- InterFACE (NCT04464603)
- Testing
- InterFACE (mHealth tool), Conventional methods
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Out-of-hospital Cardiac Arrest (OHCA), Cardiopulmonary Resuscitation (CPR)
The AIR-CPR Study: AI-Guided Chest Compressions
The AIR-CPR project aims to improve survival rates for patients with Out-of-Hospital Cardiac Arrest (OHCA) by utilizing Artificial Intelligence (AI) to optimize chest compression locations.
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), Cardiopulmonary Resuscitation (CPR), Aortic Valve Compression, Precision Resuscitation
- Trial name
- AIR-CPR (NCT07431710)
- Testing
- Device: AI-Enhanced Arterial Waveform Monitor (AIR-CPR App), AI-Guided Chest Compression Repositioning, Transesophageal Echocardiography (TEE)
- Where
- Taiwan
- Volunteers
- 255 people
- Sponsor
- Far Eastern Memorial Hospital
Heart Arrest
BC ECPR Trial for Out-of-Hospital Cardiac Arrest
The addition of an Extracorporeal-Cardiopulmonary Resuscitation (ECPR) service to a region may improve the survival of young patients with sudden unexpected cardiac arrest.The primary aim of this study is to determine the benefit…
- Trial name
- NCT02832752
- Testing
- ECPR Protocol
- Where
- 3 sites in Canada
- Volunteers
- 308 people
- Sponsor
- University of British Columbia
Out-Of-Hospital Cardiac Arrest
CPR Quality and Use of Feedback for OHCA
The purpose of this study is to investigate the quality of cardio-pulmonary resuscitation(CPR) delivered by EMS professionals and whether this quality can be improved by implementing real-time feedback during the event and an…
- Trial name
- NCT04152252
- Testing
- Real time feedback, Post-event debriefing
- Where
- Denmark
- Volunteers
- 2,989 people, healthy volunteers welcome
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Communication, Advance Directives
Choice of Diction's Effect
The purpose of the research is to determine how the language used when discussing preferences about cardiopulmonary resuscitation (CPR) affects decisions regarding this (code status)
- Conditions
- Communication, Advance Directives, Decision Making, Cardiopulmonary Resuscitation
- Trial name
- CODE (NCT04896411)
- Testing
- Alternative phrasing for no code, Standard of care for no code
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Heart; Arrest, Newborn, Birth Asphyxia
Does Higher (100% Oxygen) Versus Lower (21% Oxygen) During CC+SI During CPR of Asphyxiated Newborns Improve Time to ROSC
When newborn babies are born without a heartbeat the clinical team has to provide breathing and chest compressions (what is call cardiopulmonary resuscitation) to the newborn baby.
- Conditions
- Heart; Arrest, Newborn, Birth Asphyxia, Bradycardia Neonatal
- Trial name
- SURV1VE-O2 (NCT03902652)
- Testing
- Intervention (21% oxygen during CC+SI), Intervention (100% oxygen during CC+SI)
- Where
- Canada
- Sponsor
- University of Alberta
Cardiopulmonary Resuscitation (CPR), Basic Life Support Training Course
Evaluation of Mixed Reality Cardiopulmonary Resuscitation Training
<Study Design> This study is a cluster-randomized, stratified, non-inferiority trial designed to evaluate the feasibility, efficacy, and educational effectiveness of HEROS 4.0, a mixed-reality (MR)-based cardiopulmonary…
- Conditions
- Cardiopulmonary Resuscitation (CPR), Basic Life Support Training Course, Cardiac Arrest (CA)
- Trial name
- HEROS 4 (NCT07363772)
- Testing
- HEROS 4.0, Conventional CPR training
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Extracorporeal Cardiopulmonary Resuscitation, Cardiac Arrest
Observational Study to Assess Optimal ECPR Settings After Resuscitation
Rationale: Veno-arterial extracorporeal membrane oxygenation (vaECMO) during cardiopulmonary resuscitation (ECPR) might improve outcome after cardiac arrest.
- Trial name
- MOFE (NCT03592810)
- Testing
- Settings of the extracorporeal membrane oxygenation (ECMO)
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Erasmus Medical Center