Clinical trials: Carotenoids
Macular Degeneration
Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60
This study will explore whether taking the vitamins lutein and zeaxanthin, with or without Omega-3 fatty acid (fish oil or docosahexanoic acid, also known as DHA) will change the amount of lutein and zeaxanthin in the blood among…
- Trial name
- NCT00121589
- Testing
- Lutein
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Mild Cognitive Impairment
The Effects of a Carotenoid Intervention on Cognitive Function
Past research suggests that retinal lutein levels are related to cognitive function as measured via behavioral tests. The goal of the present study is to investigate the relationship between lutein and cognitive function in a…
- Trial name
- NCT02023645
- Testing
- active supplement
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Human Microbiome
Oral Probiotics on the Shift in Gut Microbiome and Skin Carotenoid Levels
The purpose of this study is to determine how probiotics affects circulating carotenoid levels.
- Trial name
- NCT04841694
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Vitamin A Deficiency, Low Serum Retinol
Efficacy of β-carotene Biofortified Maize in Reducing Vitamin A Deficiency Among Children
The purpose of this cluster-randomized trial is to examine whether daily consumption of β-carotene biofortified maize flour can reduce the prevalence of vitamin A deficiency and improve the vitamin A status and among 4-8 year old…
- Trial name
- NCT01695148
- Testing
- β-Carotene Biofortified Maize Flour, White Maize Flour
- Where
- Zambia
- Volunteers
- 1,228 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Oxidative DNA Damage
Biological Functions of Carotenoids in Humans
This study will examine the the efficiency fo absorption of major plant pigments, carotenoids, (lutein, beta-carotene and lycopene)and will measure the biological functions of carotenoids in healthy women in response to an 8-week…
- Trial name
- NCT00356252
- Testing
- mixed carotenoids
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tufts University
Healthy Nutrition, Healthy Diet
Baylor Infant and Toddler Biomarker of Nutrition Study
Young children rely on their foods and drinks for the nutrients they need to grow, like energy, protein, vitamins, and minerals.
- Trial name
- BITBONS (NCT05869760)
- Testing
- Carotenoid Intake, Serum carotenoid concentrations
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Carotenoids
Sweet Corn and Carotenoids
This study will assess the effect of daily yellow and white sweet corn intake on serum lutein and zeaxanthin concentrations. Skin carotenoid levels using the Veggie Meter will be assessed, and gastrointestinal symptoms and…
- Trial name
- NCT06892444
- Testing
- Yellow Sweet Corn, White Sweet Corn
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy
Pharmacokinetics of MCS in Healthy Volunteers
This study is to examine the pharmacokinetics, absorption and serum concentrations of MCS and other components after once-daily oral dosing of MCS.
- Trial name
- MCS-2-US-pk (NCT01003171)
- Testing
- MCS-2 soft-gel capsule
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Health Ever Bio-Tech Co., Ltd.
Beta-carotene Bioavailability, Vitamin A Deficiency
Effect of SNPs in the BCMO1 Enzyme
Summary: Chronic intake of foods low in vitamin A (retinol) and provitamin A forming an unbalanced diet with little variety is common in young individuals in the United Kingdom (UK) population and can lead to subclinical…
- Trial name
- BETASNP2 (NCT02276014)
- Testing
- Beta-carotene
- Where
- United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Hypercholesterolemia
Effect of High Stanol Ester Dose on Serum Lipids, Carotenoids and Fat-soluble Vitamins
The aim was to investigate the effects of the consumption of high doses of plant stanol esters on concentrations of serum lipids, carotenoids and fat soluble vitamins.
- Trial name
- maxsta (NCT00698256)
- Testing
- vegetable oil-based spread and oat-based drink (no brand name available)
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marjukka Kolehmainen
Skin Carotenoids
Assessment of the Effects of a Daily Supplement 4Life Transfer Factor Vista Containing AREDS2 Formula on Skin Carotenoid Levels Using a Non-invasive Detection
The goal of the clinical study is to evaluate the impact of daily use of a dietary supplement TF Vista containing AREDS2 formula ingredients, astaxanthin (Haematococcus pluvialis) microalgae, bilberry (Vaccinium myrtillus) fruit…
- Trial name
- NCT07513597
- Testing
- Dietary Supplement
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- 4Life Research, LLC
Healthy
Bioavailability of Pepper Carotenoids in Humans
list item one, Peppers We propose to evaluate bio absorption of pepper carotenoids in a red bell-pepper or non-pungent green jalapeno pepper. The pepper will be provided in a cooked dish.
- Trial name
- NCT00636350
- Testing
- Pepper
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Tufts University
Healthy
Bioavailability of Golden Rice Carotenoids in Humans
This investigation protocol uses an isotope reference method to evaluate bioavailability of ß-C in rice and its bioconversion to vitamin A.
- Trial name
- NCT00680355
- Testing
- golden rice, corn oil 0g, corn oil 10g
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Tufts University
Vasomotor Symptoms
Goji Berry and Vasomotor Symptoms Pilot Study
The goal of this clinical trial is to compare two forms of goji berry powder-whole goji berry powder and goji juice powder-in peri- and postmenopausal women aged 40-65 years who experience frequent vasomotor symptoms (hot…
- Trial name
- GOJI-VMS (NCT07660315)
- Testing
- Goji Berry Juice Powder, Goji Berry Powder
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Body Weight, Obesity & Overweight
Breastmilk and the Link to Overweight/Obesity and Maternal Diet in the Mother-breastmilk-child Triad
The prospective 5-month follow-up study will involve 150 mother-infant dyads grouped based on maternal baseline BMI category (normal weight, overweight, obesity).
- Conditions
- Body Weight, Obesity & Overweight, Human Milk/Breastfeeding, Body Composition
- Trial name
- BLOOM-Triad (NCT07457515)
- Where
- 4 sites in Canada, Poland
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Warsaw University of Life Sciences
Healthy, Nutrition Poor
Effects of Lutein on Visual Function
Randomized, double blind, placebo-controlled intervention trial on the ocular benefits and inflammatory markers improvements of taking FloraGLO Lutein for 9 months.
- Trial name
- NCT03113864
- Testing
- Lutein
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Iron Absorption
Effects of Vitamin A and Carotenoids on Iron Absorption
The objective of this study is to investigate the effect of vitamin A and carotenoids on iron absorption in healthy subjects with low and normal vitamin A status.
- Trial name
- NCT01493297
- Testing
- Labeled iron solutions
- Where
- Venezuela
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Eye Health, Age-related Macular Degeneration
Impact of Regular Consumption of Grapes on Eye Health in Singapore Older Adults
Aging epidemics in Singapore are rapidly increasing and Age-related macular degeneration (AMD) prevalence is significantly associated with older age.
- Trial name
- NCT05064865
- Testing
- Freeze-dried table grape powder
- Where
- Singapore
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Vitamin A Deficiency
Effect of Daily Consumption of Orange Maize on Breast Milk Retinol in Lactating Zambian Women
The purpose of the study is to determine whether daily consumption of beta-carotene biofortified maize will increase breast milk retinol concentration in lactating Zambian women.
- Trial name
- NCT01922713
- Testing
- white maize and a corn oil capsule, orange maize and a corn oil capsule, white maize and a vitamin A capsule
- Where
- Zambia
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Health Behavior
Evaluation of Changes in Skin Carotenoid Scores in Medical Students Following a Dietary Supplement-based Intervention
Skin Carotenoid Scores (SCS) are a biomarker of overall antioxidant status. This study extends an earlier study in which an increase in skin carotenoid scores (SCS) was observed in subjects who increased their intake of fruits…
- Trial name
- SCS2015 (NCT02464787)
- Testing
- LifePak Nano
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center