Clinical trials: Case-Control Studies
Rheumatic Disorder
Knowledge of Living Will in Patients With Rheumatic Diseases
The living will is a legal document derived from a communication and deliberation process, medical ethical aspect, currently regulated in Mexico by the General Health Law and the Health Law of Mexico City.
- Trial name
- NCT05676359
- Testing
- Health Assessment Questionnaire (HAQ), Depression, Anxiety and Stress Scale (DASS-21), Brief Resilient Coping Scale
- Where
- Mexico
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- National Institute of Medical Sciences and Nutrition, Salvador Zubiran
Obsessive-Compulsive Disorder
Function-metabolism Coupling in Decision-making Confidence Neural Network of Obsessive-compulsive Disorder
This study, a case-control study, aims to investigate the function-metabolism coupling in decision-making confidence neural network of obsessive-compulsive disorder.
- Trial name
- NCT05563935
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Temporomandibular Disorder (TMD), Pain Threshold
Cervical Muscle Endurance and Pressure Pain Threshold in University Students With TMD: A Case-Control Study
Aim: This study aims to compare the static endurance of cervical region muscles, pressure pain thresholds of selected muscles of the stomatognathic system, and postural characteristics in young adults with and without…
- Trial name
- TMED-CME-PPT (NCT07407127)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Assessing Motor Neuron Disease Mechanisms by Threshold Tracking Transcranial Magnetic Stimulation and Magnetic Resonance Spectroscopy
Amyotrophic Lateral Sclerosis (ALS) is a motor neuron disease, which cases the death of neurons controlling the voluntary muscles.
- Conditions
- Amyotrophic Lateral Sclerosis, Motor Neuron Disease, Cortical Excitability
- Trial name
- NCT03664206
- Testing
- MRS, conventional TMS and treshold tracking TMS
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sándor Beniczky
Molar Incisor Hypomineralization
Tooth Development in Molar Incisor Hypomineralisation
Molar incisor hypomineralization has been defined as a qualitative developmental enamel defect affecting one or more permanent first molars, often including the permanent incisors.
- Trial name
- NCT06639815
- Testing
- clinical and radiographic examination
- Where
- Turkey (Türkiye)
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Canan Bayraktar Nahir
Esophageal Squamous Cell Carcinoma
NCI UNC Project ESCC
Background: Esophageal cancer is a common cause of cancer deaths. Most cases of this cancer are esophageal squamous cell carcinoma (ESCC). Many of these cases come from two parts of the world with high-risk.
- Trial name
- NCT03206125
- Where
- 2 sites in Malawi
- Volunteers
- 648 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Cystic Fibrosis
Gut Imaging for Function & Transit in Cystic Fibrosis Study 1
Many people with Cystic Fibrosis (CF) are troubled by symptoms from their stomach and bowels: their gastrointestinal (GI) tract.
- Trial name
- GIFT-CF1 (NCT03566550)
- Testing
- MRI scans
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Scleroderma
Premature Coronary Atherosclerosis in Scleroderma
The purpose of this trial is to study the proportion of scleroderma patients who suffer from asymptomatic coronary atherosclerosis compared to healthy controls.
- Trial name
- NCT00372398
- Where
- Hong Kong
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Tuen Mun Hospital
Parkinson's Disease
Genetic Polymorphism and Parkinson's Disease in Taiwanese
To observe and analyze the correlation between Single Nucleotide polymorphisms (SNPs) and the incidence of Parkinson's disease in Taiwanese.
- Trial name
- NCT01996878
- Where
- Taiwan
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Nutrition Disorders, Migraine Disorders
Dietary Advanced Glycation End Products and Migraine
Is dietary intake of advanced glycation different between individuals with and without migraine? Is there a difference between the groups in terms of energy and nutrients? The answers to these questions are sought.
- Trial name
- NCT05747911
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Arthritic Psoriasis, Psoriasis (PsO)
Retinal Capillary Vessel Density and Foveal Avascular Zone Size in Patients With Psoriatic Arthritis: A Case-Control Study.
In terms of blood flow per unit of tissue, the retina is one of the tissues with the highest blood flow in the body. Parameters such as the thickness of the choroid layer, which plays a crucial role in maintaining normal eye…
- Conditions
- Arthritic Psoriasis, Psoriasis (PsO), Retinal Vessels
- Trial name
- PsA-RETINA (NCT07858591)
- Testing
- OCTA-SCP, OCTA-DCP, OCTA-RPC
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Gastric Cancer
Microbiota in Gastric Cancer by Gastric Mucosal Brushing
Many studies have shown a significant change of diversity and composition in gut microbiota across the gastric carcinogenesis process, particularly in patients with gastric cancer.
- Trial name
- NCT06325891
- Testing
- Gastric mucosal brushing, Gastric mucosal biopsy
- Where
- 2 sites in Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Chulalongkorn Memorial Hospital
Pancreatic Cancer Stage I, Pancreatic Cancer Stage II
Clinical Validation of Immunovia Next-Generation Blood Biomarker Test to Detect Early-Stage Pancreatic Cancer
This is a case-control study to clinically validate the performance of a protein biomarker test to differentiate Stage I and Stage II pancreatic ductal adenocarcinoma (PDAC) patient samples from samples acquired from control…
- Conditions
- Pancreatic Cancer Stage I, Pancreatic Cancer Stage II, Cancer Diagnosis, PDAC - Pancreatic Ductal Adenocarcinoma
- Trial name
- CLARITI (NCT06947382)
- Where
- 15 sites in United States, Canada and 2 more
- Volunteers
- 1,066 people, healthy volunteers welcome
- Sponsor
- Immunovia, Inc.
Bruxism, Wear, Occlusal
Effect of Bruxism on the Clinical Success of Posterior Composite Restorations
The goal of this study is to determine the effect of bruxism on the success of posterior composite restorations (PCRs) in endodontically treated teeth (ETT).
- Conditions
- Bruxism, Wear, Occlusal, Fracture
- Trial name
- Bruxism (NCT06881355)
- Testing
- Bruxism diagnosis, Clinical evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Rheumatic Diseases
Dual Task Performance in Rheumatic Diseases
Chronic pain is pain that exceeds the duration of the injury or trigger stimulus and lasts for at least three months. Recent studies show that chronic pain has devastating effects on cognitive functions by causing emotional…
- Trial name
- NCT04717505
- Testing
- Gait Assessments, Arthritis Impact Measurement Scales 2, Visual Analogue Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Endometriosis
Urinary Concentration of Phthalate Metabolites in Women With and Without Endometriosis
Exposure to endocrine-disrupting chemicals can considerably affect female reproductive system. Exposure can occur in living environments and in specific workplaces in which these substances are produced or used.
- Trial name
- FTALATENDO (NCT05551494)
- Testing
- Urinary sample
- Where
- Italy
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Chronic Obstructive Pulmonary Disease
Association Between Cardiopulmonary Function and Plantar Pressure in Patients With Chronic Obstructive Pulmonary Disease
It aims to understand the differences in everyday mobility and activity capabilities among patients with varying disease progression and severity, to serve as reference indicators for evaluating the effectiveness of pulmonary…
- Trial name
- NCT06579872
- Testing
- plantar pressure
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University
Haemophilus Influenzae Type B, Carrier State
Study to Eliminate Hib Carriage in Rural Alaska Native Villages
Hib disease rates in rural Alaska before introduction of HIb conjugate vaccine were among the highest in the world. Since vaccine introduction, rates have fallen by 90% but the disease has not been eliminated.
- Trial name
- NCT00153556
- Testing
- Hib conjugate vaccine (HbOC, Wyeth Vaccines)
- Where
- United States
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Multi-drug Resistant Tuberculosis
Case Control Study of Vitamin D Status and Adult Multidrug-resistant Pulmonary Tuberculosis in Maharashtra, India
India has the highest incidence of and mortality from multi-drug resistant tuberculosis (MDR-TB) globally. Vitamin D status may be an important determinant of MDR-TB infection and treatment outcomes; however, observational…
- Trial name
- NCT04342598
- Testing
- Serum Vitamin D
- Where
- India
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Temporomandibular Disorders (TMD), Pregnancy
Temporomandibular Joint Function, Oral Habits and Pain Complaints of Pregnant Women
The aim of this study is to examine the temporomandibular joint functions, oral habits and pain complaints of pregnant women. .
- Trial name
- NCT06760884
- Where
- Turkey (Türkiye)
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University