Clinical trials: Central Venous Catheters
Atrial Fibrillation - Symptomatic
Low Voltage-Directed Catheter Ablation for Atrial Fibrillation
A two-pronged approach to evaluate long term success of non-paroxysmal ablation when using a: 1. specified low voltage-directed with pulmonary vein isolation (LD+PVI) approach compared to , 2.
- Trial name
- NCT03355456
- Testing
- Radiofrequency ablation
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Ohad Ziv
Patient Safety During Central Venous Catheterization
Ideal Depth of Guide Wire for Central Catheterization
prospective randomized double-blind controlled study
- Trial name
- NCT02711761
- Testing
- central venous catheterization
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University Hospital
Central Venous Catheter
Evaluation of Performance Over Dwell Time and Safety of the Central-venous Catheters Certofix® Paed
Central venous catheterisation is a medical technique that has become established over many decades and can be rated as State of the Art.
- Trial name
- NCT05124821
- Testing
- Central venous catheter intended to be used for children during routine clinical practice
- Where
- 3 sites in Germany, Italy
- Volunteers
- 100 people
- Sponsor
- B. Braun Melsungen AG
Nursing Students
Dressing of Tunneled Central Venous Catheter
The purpose of this study was to compare the performance of nursing undergraduates in dressing of tunneled central venous access in the simulator, according to the aid of a preceptorship or an auto-instructional guide.
- Trial name
- NCT01614314
- Testing
- Preceptorship, Auto-instructional guide
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- University of Sao Paulo
Cystic Fibrosis
Study of Peripherally Inserted Venous Catheters in Cystic Fibrosis Patients
According to the U.S. CF Foundation Patient Registry, more than 25% of children and 40% of adults were treated with intravenous (IV) antibiotics for flares of lung disease in 2016.
- Trial name
- PICC-CF (NCT03674216)
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Jonathan B. Zuckerman
Dysfunctional Central Venous Access Catheters
A Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters
This was a Phase III, randomized, double-blind, placebo-controlled study that was conducted at 24 centers in the United States and Canada.
- Trial name
- TROPICS 1 (NCT00395876)
- Testing
- tenecteplase
- Volunteers
- 100 people
- Sponsor
- Genentech, Inc.
Central Line Complication
Short-axis/out-of-plane Approach Versus Oblique- Axis Approach for US Guided IJV Catheterization in Infants.
The investigators will measure and compare the rate of acute complications, success rate, number of attempts to successful cannulation between ultrasound-guided short axis approach and oblique axis approach during internal…
- Trial name
- NCT06652490
- Testing
- Short-axis/out-of-plane approach versus oblique- axis approach for ultrasound-guided internal jugular venous catheter.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Central Line Associated Blood Stream Infections (CLABSI)
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults And Adolescent Participants Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
This is a Phase 3, randomized, double-blind, controlled, adaptive, 2-arm, multicenter study to demonstrate the efficacy and safety of DefenCath in adult and adolescent participants receiving home Total Parenteral Nutrition (TPN)…
- Trial name
- NCT06822426
- Testing
- (taurolidine and heparin) catheter lock solution, Heparin
- Where
- 24 sites in United States, Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- CorMedix Therapeutics
Catheterization, Central Venous, Catheter-Associated Infections
Prevention of Catheter-Associated Infection With the Skin Disinfectant Octenidine Dihydrochloride
Health-care-acquired infections are of tremendous importance for patients, especially catheter-associated infections. More than 40% of all bloodstream infections are associated with central venous catheters (CVC; catheters which…
- Conditions
- Catheterization, Central Venous, Catheter-Associated Infections, Bacterial Infections, Bacteremia
- Trial name
- NCT00515151
- Testing
- 0.1% Octenidine with 30% 1-propanol and 45% 2-propanol, 74% Ethanol with 10% 2-propanol
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital Freiburg
Catheter Related Complication
Incidence and Clinical Progression of Asymptomatic PICC-Related Thrombosis in Solid Cancer Patients
In this prospective cohort study, the investigators evaluated the incidence of superficial vein thrombosis, deep vein thrombosis, and fibroblastic sleeve formation in solid cancer patients undergoing chemotherapy.
- Trial name
- NCT05966909
- Testing
- Doppler Ultrasound
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Healthcare Associated Infection, Critically Ill
Dynamic Full-Field Optical Coherence Tomography for Structural and Microbiological Characterization of Central Venous Catheter-deposited Biofilm in Critically Ill Patients
29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, with a significant proportion related to central venous catheters, and an influence on both morbility and mortality.
- Conditions
- Healthcare Associated Infection, Critically Ill, Central Venous Catheter Associated Bloodstream Infection
- Trial name
- OCT-BIO-CVC (NCT06216080)
- Testing
- D-FF-OCT analysis of CVC
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier William Morey - Chalon sur Saône
Vascular Access Devices, Central Venous Catheter
Safety and Efficacy of Midline and PICC
The purpose of this study is to assess the non-inferiority for safety and efficacy of using Midline in comparison with PICC for intravenous therapy that do not require a central catheter.
- Trial name
- MidLine_PICC (NCT03502980)
- Testing
- Bard PowerPICC, Bard PowerMidline catheter
- Where
- Canada
- Volunteers
- 293 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Health Care Associated Infection, Ventilator Associated Pneumonia
Daily Chlorexidine Bath for Health Care Associated Infection Prevention
Cluster randomized controlled trial comparing two bathing strategies in critically ill patients. The intervention group will receive daily bathing with chlorhexidine. The control group will receive usual care.
- Conditions
- Health Care Associated Infection, Ventilator Associated Pneumonia, Central Line-associated Bloodstream Infection (CLABSI), Catheter-Associated Urinary Tract Infection
- Trial name
- CLEAN-IT (NCT05485051)
- Testing
- 2% chlorhexidine digluconate solution with surface-active agents, Usual Baths
- Where
- 16 sites in Brazil
- Volunteers
- 15,730 people
- Sponsor
- Hospital do Coracao
Pediatric Cancer, Pediatric Oncology
Central Venous Catheter Care Training for Pediatric Oncology Nurses
The knowledge level of nurses regarding care techniques plays a crucial role in the prevention of central venous catheter-related infections.
- Conditions
- Pediatric Cancer, Pediatric Oncology, Central Venous Catheter, Central Venous Catheter Placement
- Trial name
- NCT07345598
- Testing
- CVC Care Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Sepsis
Effect of Taurolidin on Prevention of Bloodstream Infection
Home parenteral nutrition (HPN) is a validated technique for patients with various intestinal disease leading to chronic malabsorption or obstruction, whatever the aetiology.
- Trial name
- Nutrilock (NCT00545831)
- Testing
- Taurolidine, Physiologic Serum
- Where
- 7 sites in France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Rouen
Central Venous Catheters, Vascular Access Devices
Using A Gelatin-Based Model In USG-Guided Jugular Venous Catheter Placement Training
An education model with a homemade jugular venous catheterization model will be compared to the conventional training model for ultrasound-guided central jugular line catheterization.
- Conditions
- Central Venous Catheters, Vascular Access Devices, Education, Simulation Training
- Trial name
- NCT03996733
- Testing
- Lecture, Demo Video, UltrasoundImaging
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Zeki Tuncel Tekgul
Kidney Failure, Chronic, Hemodialysis Complication
The Pristine Post-Market Study
This is a prospective, multi-center, single-arm study designed to assess the safety and performance of the Pristine™ Long-Term Hemodialysis Catheter.
- Conditions
- Kidney Failure, Chronic, Hemodialysis Complication, Hemodialysis Catheter Infection, Hemodialysis Access Failure
- Trial name
- NCT05228132
- Testing
- Pristine™ Long-Term Hemodialysis Catheter
- Where
- 6 sites in United States
- Volunteers
- 142 people
- Sponsor
- C. R. Bard
Breast Cancer
Iterative PICC Placement Versus Long Term Device
Peripherally Inserted Central Catheter (PICC) and port-a-cath (PAC) are the most commonly medical devices used for the administration of chemotherapy.
- Trial name
- PICC One Day (NCT02784730)
- Testing
- Iterative PICC placement, Long term PAC placement
- Where
- France
- Sponsor
- Centre Leon Berard
Venous Thromboembolism (VTE)
Venous Thromboembolism (VTE) Prophylaxis With REGN7508 and REGN9933 in Adult and Adolescent Participants With a Peripherally Inserted Central Catheter (PICC)
This study is researching 2 different experimental drugs called REGN7508 and REGN9933 (called "study drugs"). The study is focused on people who have a tube placed in a vein to receive treatment (called Peripherally Inserted…
- Trial name
- ROXI-PEAK (NCT07697599)
- Testing
- REGN7508, REGN9933
- Where
- Georgia
- Volunteers
- 1,908 people
- Sponsor
- Regeneron Pharmaceuticals
Infection
Comprehensive Evaluation of a Central Line Simulation Course
An estimated 250,000 cases of central line-associated bloodstream infections occur in US hospitals annually, and an estimated 30,000 to 62,000 patients die as a result, the marginal cost of which to the health-care system is…
- Trial name
- NCT01165398
- Where
- United States
- Volunteers
- 383 people
- Sponsor
- Lehigh Valley Hospital