Clinical trials: Central Venous Oxygen Saturation
Heart Failure
Validation of a Non-invasive Assessment of Central Venous Oxygen Saturation by Using MRI
BOLD measured with MRI may be a useful noninvasive method for the assessment of right ventricular O2 saturation. A validation of this method against right heart catheterization has not been fully performed.
- Trial name
- NCT05161884
- Where
- Germany
- Volunteers
- 135 people
- Sponsor
- German Heart Institute
Heart; Dysfunction Postoperative, Cardiac Surgery, C.Surgical Procedure; Cardiac
Goal Directed Therapy Aiming to Optimise Oxygen Central Venous Saturation in Children Undergoing Cardiac Surgery
The purpose of this study is evaluate goal-directed therapy with continuous central venous saturation compared to standard therapy in children undergoing cardiac surgery.
- Trial name
- NCT03469440
- Testing
- Continuous central venous oxygenation monitoring, Standard protocol
- Where
- Brazil
- Volunteers
- 65 people
- Sponsor
- Instituto do Coracao
Post Arrest Patients
Central Venous Oxygen Saturation Prognostic Impact in Post Arrest Patients
The study aim will be to assess the prognostic impact and value of central venous oxygen saturation on post arrest patients.
- Trial name
- NCT07107776
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Coronary Artery Disease, Hemodynamic Monitoring
Single Transpulmonary Thermodilution and Continuous Monitoring of Central Venous Oxygen Saturation During Off-pump Coronary Surgery
The aim of the present study was to evaluate the usefulness of an algorithm based on hemodynamic parameters obtained by single transpulmonary thermodilution (STD) combined with continuous monitoring of central venous oxygen…
- Conditions
- Coronary Artery Disease, Hemodynamic Monitoring, Goal Directed Therapy
- Trial name
- OPCAB (NCT00624494)
- Testing
- Conventional monitoring, Advanced monitoring
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Northern State Medical University
Central Venous Oxygen Saturation, Anaemia
Transfusion Practices in Intensive Care Units: a Hungarian Nationwide Survey
The aim of our data analysis-based questionnaire study is to assess the daily transfusion practices used in the care of critically ill patients in intensive care units in Hungary.
- Conditions
- Central Venous Oxygen Saturation, Anaemia, Lactate, Transfusion
- Trial name
- NCT07532772
- Testing
- Survey using a questionnaire.
- Where
- Hungary
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Pest County Flór Ferenc Hospital
Branch Retinal Artery Occlusion, Central Retinal Artery Occlusion
Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye
Canadians fear loss of vision more than any other disability. Vision loss has an enormous impact on quality-of-life and is extremely costly from a societal and economic perspective.
- Conditions
- Branch Retinal Artery Occlusion, Central Retinal Artery Occlusion, Branch Retinal Vein Occlusion, Central Retinal Vein Occlusion
- Trial name
- NCT01348633
- Where
- Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Ischemic Heart Disease, Valvular Heart Disease
Vigileo FloTrac vs Pulmonary Artery Catheter
To study the role of Vigileo monitor using the FloTrac sensor to measure cardiac output using the pulse contour analysis as well as central venous oxygen saturation monitoring as a guide for tissue perfusion.
- Trial name
- NCT00641290
- Testing
- Vigileo FloTrac Sensor
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- Hospital Sultanah Aminah Johor Bahru
Anemia, Blood Transfusion
Evaluation of Alternative Transfusion Triggers in Hemodynamically Stable, Non-Ventilated Cancer Patients
This is a prospective, single-center observational study conducted at the Kazakh Institute of Oncology and Radiology. The study included 107 clinically stable adult patients with cancer who required red blood cell transfusion…
- Conditions
- Anemia, Blood Transfusion, Cancer, Hemoglobin
- Trial name
- NCT06952361
- Testing
- Red blood cell transfusion
- Where
- Kazakhstan
- Volunteers
- 107 people
- Sponsor
- Ardak Arynov
Valvular Heart Disease
Comparison of Goal-directed Algorithms of Hemodynamic Therapy After Combined Valve Repair
Valvular repair and repair surgery is rapidly progressing yet rather challenging aspect of current cardiosurgical practice. Several approaches were introduced into the clinical practice to alleviate systemic inflammatory response…
- Trial name
- NCT01276444
- Testing
- Swan-Ganz catheter, transpulmonary thermodilution + central venous saturation
- Where
- Russia
- Volunteers
- 43 people
- Sponsor
- Northern State Medical University
Septic Shock
The Effect of Lactate Clearance Oriented Haemodynamic Therapy on the Outcome of Patients With Septic Shock
The purpose of this study is to explore and assess possible outcome benefits of lactate clearance>30% vs ScvO2 ≥70% in 6 hours as the protocol goal that evaluated adequacy of during early resuscitation of septic shock through a…
- Trial name
- NCT02566460
- Testing
- Resuscitation
- Volunteers
- 360 people
- Sponsor
- Peking Union Medical College Hospital
Acute Kidney Injury
Continuous Central Venous Oxygen Saturation Measurement as a Tool to Predict Hemodynamic Instability Related to Renal Replacement Therapy in Critically Ill Patients
Acute kidney injury (AKI) is common in intensive care unit (ICU) and inducing a high morbidity and mortality. In severe forms of AKI (more than 25% of AKI patients admitted to the ICU), renal replacement therapy (RRT) is often…
- Trial name
- SoVHIRR (NCT05897840)
- Testing
- Fiber-optic probe CeVOX
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Hemodynamics, Renal Dialysis
Presep and Vascath Interaction Study
This is a prospective, observational study to compare presep(tm) catheter central vein mixed venous oxygen saturation before and after dialysis is initiated via the vascath(tm) central venous dialysis catheter to evaluate device…
- Conditions
- Hemodynamics, Renal Dialysis, Sepsis, Shock
- Trial name
- NCT00739089
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Sepsis, Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy
Comparison of Central Venous Oxygen Saturation Measurements by Non-invasive Mespere Venous Oximeter and Central Venous Catheter
The intent of this study is to validate the venous blood oxygenation measurements of the Mespere VA Oximeter compared to the saturations measured by venous blood sampling through an inserted central vein catheter, which is…
- Conditions
- Sepsis, Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy, Cardiogenic Shock Post Myocardial Infarction, Hypoxemic Respiratory Failure.
- Trial name
- NCT01788956
- Testing
- Mespere Venous Oximeter, Co-Oximeter
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Mespere Lifesciences Inc.
Undergoing Nonemergent Cardiac Surgery, Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure)
SvO2 Trigger in Transfusion Strategy After Cardiac Surgery
Current international guidelines suggest a restrictive transfusion strategy, setting that Hb level at 7 g/dl is a reasonable threshold.
- Conditions
- Undergoing Nonemergent Cardiac Surgery, Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure), Anemia (<9g/dL) Requiring Blood Transfusion, Hemodynamic and Respiratory Stability
- Trial name
- ReTSEACS (NCT02761564)
- Testing
- Red blood cell tranfusion, ScvO2 measure
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Sepsis and Septic Shock
Dynamic SvO2 in Predicting Fluid Responsiveness in Septic Shock
This prospective observational diagnostic accuracy study investigates the efficacy of dynamic central venous oxygen saturation in predicting fluid responsiveness in septic shock, compared to measurements obtained using…
- Trial name
- NCT07516236
- Testing
- Measuring dynamic central venous oxygen saturation (ScvO2) at baseline and after fluid challenge. Measuring Cardiac output by echocardiography or cardiometry at baseline and after fluid challenge.
- Where
- Egypt
- Volunteers
- 115 people
- Sponsor
- Menoufia University
Post Operative Fluid Management
Fluid Management Surgical Patients in Intensive Care Unit.
The aim of this study is to evaluate the efficacy of lactate clearance (LCR) versus central venous oxygen saturation (ScVO2) to guide fluid management for post-operative patients in the intensive care unit (ICU).
- Trial name
- NCT03455296
- Testing
- fluid therapy; crystalloid
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Hepatology & Tropical Medicine Research Institute
Sepsis, Severe Sepsis
Microcirculatory Oxygen Uptake in Sepsis
Forearm vasoocclusive testing (VOT) will be performed with laser-doppler spectrophotometry system in septic patients on ICU. Microcirculatory oxygen uptake will be checked for prognostic value and for associations with tissue…
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- NCT02430142
- Testing
- Vasoocclusive testing
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- Universitätsmedizin Mannheim
Oxygen Saturation and the Relationship to Other Cardiac Variables, Maintenance Hemodialysis
Hypoxemia in Maintenance Hemodialysis Patients
Previous research has shown that many patients with kidney failure undergoing chronic hemodialysis (HD) have a very low venous oxygen concentration, which may further decrease during dialysis treatments.
- Conditions
- Oxygen Saturation and the Relationship to Other Cardiac Variables, Maintenance Hemodialysis, Kidney Failure, Chronic
- Trial name
- NCT03045796
- Testing
- Oxygen Saturation measured by WristOx
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Hemodynamic Instability
Respiratory Variation in Central Venous Oxygen Saturation Predicts Volume Responsiveness in Hemodynamically Unstable Patients Under Mechanical Ventilation : a Prospective Cohort Study
Vascular filling is the main treatment of hypovolemia. Hypovolemia diagnosis can be difficult in some situations and need to be confirmed with other investigations.
- Trial name
- VOS-HI (NCT02142985)
- Testing
- Sodium Chloride 0.9% Intravenous
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- University of Monastir
Severe Sepsis, Septic Shock
Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring
The purpose of this study was to compare ACCM/PALS guidelines performed with and without central venous oxygen saturation monitoring on the morbidity and mortality rate of children with severe sepsis and septic shock.
- Trial name
- NCT00407823
- Testing
- Central venous oxygen saturation continuous monitoring
- Where
- 2 sites in Brazil
- Volunteers
- 268 people
- Sponsor
- University of Sao Paulo