Clinical trials: Cerebral Hemiplegia
Hemiplegic Stroke, Hemiplegic Cerebral Palsy
Evaluating Human-Machine Interfaces in a Robotic Thumb Orthosis
We plan to investigate whether the Isolated Orthosis for Thumb Actuation (IOTA) can effectively facilitate the ability of participants to perform a specific set of clinically relevant tasks conducted in a clinic setting.
- Trial name
- IOTA (NCT01973426)
- Testing
- Isolated Orthosis for Thumb Actuation (IOTA)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wyss Institute at Harvard University
Congenital Hemiplegia, Unilateral Cerebral Palsy
Combining biomArkers and Tele-health Solutions for Delivering at Home and in the Community Precision Medicine for the Upper Limb in cHildren With HEMIplegia Due to Stroke
Paediatric (including perinatal) stroke has an incidence of between 1.3 and 13.0 per 100.000 yearly in Europe. 1/3 of children with neonatal and 50% of post-natal stroke will develop a hemiplegia with upper limb being generally…
- Trial name
- CATCH-HEMI (NCT06012617)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- IRCCS Fondazione Stella Maris
Stroke, Hemiplegia
Efficacy and Safety Study of rTMS for Upper Extremity Motor Function Recovery in Ischemic Stroke Patients
The purpose of this study is to Evaluate Efficacy and Safety of rTMS 『TMS』 for Upper Extremity Motor Function Recovery in Patients with Ischemic Stroke
- Trial name
- TAMAS (NCT02082015)
- Testing
- Low frequency rTMS
- Where
- 3 sites in South Korea
- Volunteers
- 77 people
- Sponsor
- Seoul National University Bundang Hospital
Children With Hemiplegia
Sensory Integration Versus Bobath on Hand Function in Hemiplegia
Hand skills do not develop in isolation; it is the result of neurologic development, physiologic maturation and adaptation, and functional development of learned patterns of motion and motor learning Hand skills in HCP are very…
- Trial name
- NCT06955247
- Testing
- sensory motor integration, bobath technique
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Stroke
Pediatric Hemiplegia: Synergistic Treatment Using rTMS and CIT
The strategy in rehabilitating pediatric hemiplegia is to overcome "developmental disuse". Disruption of the excitability in the non-stroke hemisphere, with resultant increased excitability (disinhibition) in the stroke…
- Trial name
- NCT01104064
- Testing
- real rTMS combined with constraint induced therapy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Minnesota
Cerebral Palsy, Spasticity
Exopulse Mollii Suit, Motor Functions & CP Children With Cerebral Palsy
Cerebral Palsy (CP) is is estimated to be around 1.5-3 per live birth, with prenatal factors accounting for 75% of cases. CP appears in early childhood and persists with age and is characterized by permanent lesions or…
- Conditions
- Cerebral Palsy, Spasticity, Muscle, Pain Syndrome
- Trial name
- EXOCEP2GER (NCT05885139)
- Testing
- Exopulse Mollii Suit
- Where
- 2 sites in Germany
- Volunteers
- 34 people
- Sponsor
- Exoneural Network AB
Stroke
Effect of Constraint-Induced Gaming Therapy in an Acute Care Setting
Current protocols for therapy on a rehabilitation unit call for intensive rehabilitation composed of high intensity, long duration therapy.
- Trial name
- CIT (NCT03578536)
- Testing
- Recovery Rapids
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- VA Office of Research and Development
Stroke, Hemiplegia
Effects of the Quantity of Repetitive Transcranial Magnetic Stimulation(rTMS) on the Recovery After Stroke
The aim of this multicentric double blind study (randomized study) is to demonstrate the relationship between the amount of rTMS and the efficacy in the treatment of upper extremity motor deficits of stroke patients.
- Trial name
- NCT01311271
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- South Korea
- Volunteers
- 2 people
- Sponsor
- Seoul National University Bundang Hospital
Hemiplegia, Hemiplegic Cerebral Palsy
AOT and ICT for Hemiplegia
A new rehabilitative approach, called AOT, based on the recent discovery of mirror neuron system (MNS), has been used with promising results on the Upper Limb (UL) function in some studies in children with Cerebral Palsy (CP).The…
- Trial name
- Tele-UPCAT (NCT03094455)
- Testing
- Experimental group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Fondazione Stella Maris
Stroke, Ischemic, Stroke, Acute
Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients
This is a randomized clinical trial to study the effect of tDCS in participants with subacute ischemic stroke, the study participants will be randomly assigned into three groups; bihemispheric, unihemispheric and sham group.
- Conditions
- Stroke, Ischemic, Stroke, Acute, Stroke, Lacunar, Hemiparesis
- Trial name
- NCT04770363
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Hemiplegia, Stroke
Comparison of the Efficacy of Ultrasound Guided vs Non-guided Suprascapular Nerve Block Treatment in Stroke Patients
The aim of this study is to compare the effectiveness of ultrasound-guided and non-guided suprascapular nerve block in the treatment of patients with hemiplegic shoulder pain, which is one of the most common post-stroke…
- Trial name
- NCT05260125
- Testing
- Ultrasound-guided Suprascapular Nerve Block, Anatomical Landmark-guided Suprascapular Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Abant Izzet Baysal University
Hemiplegia; Congenital
The Efficacy of Two Models of Intensive Upper Limb Training on Quality of Life in Children With Congenital Hemiplegia
This study compared the effectiveness of two-mode of activity-based upper limb rehabilitation (Modified Constraint-Induced Movement Therapy and Bimanual training) on health-related quality of life outcomes in school-aged children…
- Trial name
- NCT04425980
- Testing
- Modified Constraint-Induced Movement Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Hemiplegia
Quantification of Arm Non-Use After a Stroke
Reproducibility assessment of a quantitative measure of the amount of trunk compensation by kinematic analysis in a grasping task in stroke patients.This "maladaptive trunk compensation" is suspected to be underlined by "arm…
- Trial name
- NCT02326688
- Testing
- Kinematic analysis of trunk compensation
- Where
- France
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Infantile Hemiplegia
Intensive Robotic Rehabilitation in Children With Hemiparesia Using GEOSYSTEM
Cerebral palsy is the most frequent motor deficiency in children. Among other, it can leads to spastic diplegia or hemiplegia. Walking abilities is an important skill to the families' point of view in term of independence in…
- Trial name
- RIPHIGEO (NCT04246788)
- Testing
- Intensive robotic rehabilitation, classical physiotherapy
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hemiplegic Cerebral Palsy
Effects of TOA Versus PNF Techniques on Trunk Control in Children With Hemiplegic Cerebral Palsy
Cerebral palsy occurs in 2-2.5 per 1000 live births, seems to be the most common cause of lifelong physical disability, and has an impact on the child, caregivers, and society.
- Trial name
- NCT06232330
- Testing
- Group A, Group B
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Perinatal Stroke, Hemiplegic Cerebral Palsy
Stimulation for Perinatal Stroke Optimizing Recovery Trajectories
Perinatal stroke causes lifelong neurological disability and most hemiparetic cerebral palsy (CP). With morbidity spanning diverse aspects of a child's life and lasting for decades, global impact is large, including 10000…
- Trial name
- SPORT (NCT03216837)
- Testing
- Cathodal transcranial direct current stimulation
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- University of Calgary
Stroke, Hemiplegia
Effectiveness of AOT Based on Virtual Reality in Stroke Rehabilitation.
Rehabilitation of paretic stroke patients, aimed to improve function of the impaired upper limb, uses a wide range of intervention programs.
- Conditions
- Stroke, Hemiplegia, Hemiparesis
- Trial name
- NCT05163210
- Testing
- AO+VR, CO+VR
- Where
- 2 sites in Italy
- Volunteers
- 48 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Upper Extremity Hemiplegia, Stroke
Contralaterally Controlled Functional Electrical Stimulation Plus Video Games for Hand Therapy After Stroke
Determine if adding a video game component to an electrical stimulation therapy improves hand function in stroke patients
- Trial name
- NCT03058796
- Testing
- Contralaterally Controlled Functional Electrical Stimulation (CCFES), Hand Therapy Video Games
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- VA Office of Research and Development
Stroke, Gait, Hemiplegic
GaitBetter: Motor and Cognitive Training for Gait Rehabilitation and Falls Prevention in Stroke Survivors.
In this research study, the investigators aim to test the usability and efficacy of the GaitBetter system for gait rehabilitation after stroke.
- Conditions
- Stroke, Gait, Hemiplegic, Hemiplegia
- Trial name
- NCT04625127
- Testing
- Treadmill gait training with GaitBetter, Treadmill gait training with GaitBetter + Standard of care, Standard of care
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Spaulding Rehabilitation Hospital
Hemiplegia
Deep Trunk Muscle Activation and Balance in Post-Stroke Hemiplegia
Patients with post-stroke hemiplegia frequently exhibit balance impairments driven by multiple pathophysiological mechanisms. Although the role of core musculature in maintaining normal posture and balance is well established…
- Trial name
- NCT06181877
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital