Clinical trials: Cervical Cancer
Cervical Cancer, HPV Infection
Clinic or Self-Sampling for Cervical Cancer Screening
Objective: The aim of this project was to determine the effect of clinic or self-sampling on attendance, attitudes, and anxiety in cervical cancer screening.
- Trial name
- NCT06177236
- Testing
- cervical cancer screening
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Metastatic Melanoma, Metastatic Breast Cancer
Quantifying Systemic Immunosuppression to Personalize Cancer Therapy
It is nowadays well established that the immune system can profoundly influence disease outcome in cancer patients. Increasing evidence is indeed showing that patients displaying spontaneous T cell-mediated immune response…
- Conditions
- Metastatic Melanoma, Metastatic Breast Cancer, Advanced Renal Cell Carcinoma, Squamous Cell Carcinoma of Head and Neck
- Trial name
- SERPENTINE (NCT04941365)
- Testing
- single arm
- Volunteers
- healthy volunteers welcome
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
HIV Infection, Human Papillomavirus-Related Cervical Carcinoma
Enhancing Cervical Cancer Screening and Treatment in Women Living With HIV in Kenya, the ENHANCE LINKAge Trial
Background In sub-Saharan Africa (SSA), human papillomavirus (HPV) and HIV create a dual burden of disease that causes significant morbidity and mortality in the form of cervical cancer (CC).
- Conditions
- HIV Infection, Human Papillomavirus-Related Cervical Carcinoma, Screening Strategy
- Trial name
- NCT06708351
- Testing
- Best Practice, Health Promotion and Education, HPV Self-Collection
- Where
- Kenya
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Infections, HPV Infection
Implementation of Screen, Treat, and Triage for Women Living With HIV in La Romana (iSTAR)
This study aims to conduct a randomized controlled trial to evaluate the effectiveness of same-day HPV-based screen and treat among women living with HIV (WLH) in La Romana, Dominican Republic.
- Conditions
- HIV Infections, HPV Infection, Cervical Cancer
- Trial name
- (iSTAR) (NCT07225530)
- Testing
- Screen, Triage, and Treat
- Where
- Dominican Republic
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Columbia University
Human Papillomavirus, Cervix Cancer
Prevention of HPV in the School Health Service
The last ten years sexually transmitted infections (STI) have substantially increased among adolescents. STI can lead to individual suffering and have a negative effect on the future reproductive health and also increase the need…
- Trial name
- NCT02280967
- Testing
- Education about HPV by school nurse
- Where
- Sweden
- Volunteers
- 832 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Lung Carcinoma, Head and Neck Carcinoma
A New Way to Share Radiation Therapy Plans Between Doctors, CORRECT Trial
This clinical trial tests a new way to share radiation therapy plans using the Collaborative Oncology between Radiologists and Radiation oncologists for the Evaluation of Contoured Targets (CORRECT) workflow to improve…
- Trial name
- CORRECT (NCT07282444)
- Testing
- Training and Education, Communication Intervention, Survey Administration
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Adenocarcinoma of the Gastroesophageal Junction, Esophageal Cancer
Study of Blood and Tissue Samples From Patients With Stomach Cancer, Esophageal Cancer, or Gastroesophageal Junction Cancer
RATIONALE: Collecting and storing samples of tissue, blood, and saliva from patients with cancer to test in the laboratory may help the study of cancer in the future.
- Conditions
- Adenocarcinoma of the Gastroesophageal Junction, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00963092
- Testing
- DNA analysis, RNA analysis, microarray analysis
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Cancer Research UK
Oral Cancer
Validation of DNA Methylation Biomarkers for Oral Cancer Detection-Follow up Study
This is a follow up study which aims to evaluate the correlation between several methylated genes (potential biomarkers) and oral cancers.
- Trial name
- NCT02902406
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Esophageal Cancer, Head and Neck Cancer
Early Detection of Esophageal Squamous Cancer With the Capsule Sponge Device
Esophageal squamous cell carcinoma accounts for ~90% of the nearly half-million annual incident cases of esophageal cancer worldwide.
- Conditions
- Esophageal Cancer, Head and Neck Cancer, Squamous Cell Carcinoma
- Trial name
- ANGELA (NCT06418516)
- Testing
- Capsule-sponge
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Nasopharyngeal Carcinoma
Screening Nasopharyngeal Carcinoma With EBV Associated Biomarkers in Zhongshan City
The study includes two cohorts: (1) a serological screening cohort; (2) a serological and EBV DNA screening cohort. All participants will be tested for EBNA1-IgA, VCA-IgA, BNLF2b total antibodies (P85-Ab), with additional plasma…
- Trial name
- NCT04085900
- Testing
- Blood and saliva, P85-Ab, EBNA1-IgA, VCA-IgA, Consecutive EBV DNA testing
- Where
- 2 sites in China
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan People's Hospital, Guangdong, China
Gastric Cancer, Esophagus Cancer
Exosome-based Liquid Biopsies for Upper Gastrointestinal Cancers Diagnosis
This study constitutes a case-control investigation employing a retrospective approach. Plasma samples from individuals with esophageal cancer, benign esophageal diseases, gastric cancer, benign gastric diseases, and a healthy…
- Trial name
- NCT06278064
- Testing
- Gastric Cancer, Esophagus Cancer
- Where
- 3 sites in China
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Thyroid Cancer, Papillary, Leptin Levels
Leptin Levels in Papillary Thyroid Cancer
The purpose of this study is to evaluate Leptin levels in females, in the setting of papillary thyroid cancer, benign thyroid nodules, and in normal females without thyroid disease.
- Trial name
- LL-PTC (NCT01659385)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Cervical Intraepithelial Neoplasia, Cervical Cancer
Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls
The primary objective of this study is to evaluate the immuno-persistence (type specific IgG antibody) of the tested vaccine administered in girls aged 9-17 years ,comparing to young healthy adults of 18-26 years who received the…
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Vaginal Intraepithelial Neoplasia, Vulvar Intraepithelial Neoplasia
- Trial name
- NCT03206255
- Testing
- 3 doses of HPV 16/18 bivalent vaccine, 2 doses of HPV 16/18 bivalent vaccine
- Where
- China
- Volunteers
- 940 people, healthy volunteers welcome
- Sponsor
- Jun Zhang
Cervical Cancer
Post-Approval Safety Monitoring Program to Assess the Safety Profile of GARDASIL in China Usual Practice
This is a post-Approval Safety Monitoring Program to assess the safety profile of GARDASIL in china usual practice.
- Trial name
- NCT03659110
- Testing
- HPV 4
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beijing Chaoyang District Centre for Disease Control and Prevention
HNSCC
WGA in Platinum-refractory HNSCC Underwent Nivolumab
To choose a subgroup who could clearly benefit from Nivolumab, we are proposing a prospective observational study. Whole-genome study (WGS) analysis will be performed on archived cancer tissues from patients who were (1)…
- Trial name
- NCT03917537
- Testing
- HNSCC patients have used Nivolumab
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Thyroid Cancer, Large Language Models
Evaluation of an Artificial Intelligence-enabled Clinical Assistant to Support Thyroid Cancer Management
This study aims to evaluate the clinical feasibility of adopting artificial intelligence (AI)-based models to improve clinical management of thyroid cancer.
- Trial name
- NCT07234539
- Testing
- AI-enabled clinical assistant
- Where
- 2 sites in Hong Kong
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Human Papilloma Virus
A Dose Reduction Immunobridging and Safety Study of Two HPV Vaccines in Tanzanian Girls
Cervical cancer is the most common cancer in women aged 15-44 years in East Africa, and mortality rates are very high. HPV vaccines are most effective if given to girls who have not yet acquired HPV infection.
- Trial name
- DoRIS (NCT02834637)
- Testing
- bivalent HPV vaccine, nonavalent HPV vaccine
- Where
- Tanzania
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Oral Premalignant Lesions as Leukoplakia and Lichen Planus, Oral Cancer
Dipeptidyl Peptidase-4 Link With Oral Cancer and Premalignant Lesions
Aim: The current study targets linking serum and salivary dipeptidyl peptidase-4 with oral squamous cell carcinoma and comparing it with potentially malignant lesions and control to validate dipeptidyl peptidase-4 as a diagnostic…
- Trial name
- NCT06087042
- Testing
- serum and unstimulated salivary samples
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Hpv, HPV 16 Infection
SELF-CERV Pivotal Study: SELF-Collection for CERVical Cancer Screening
The goal of this method comparison study is to compare the detection of hrHPV collected using the Teal Wand Self-Collection device to hrHPV detected from HCP (health care provider) cervical collection using primary HPV testing…
- Conditions
- Hpv, HPV 16 Infection, HPV Infection, High Risk HPV
- Trial name
- NCT06120205
- Testing
- Teal Wand Self-Collection Device Group
- Where
- 15 sites in United States
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Teal Health, Inc.
Barretts Esophagus, High Grade Dysplasia
Endoscopic Tri-Modal Imaging in Patients With Barrett's Esophagus
This study is being done to determine if a new endoscope will help doctors identify pre-cancer or early cancer lesions in patients who have Barrett's esophagus.
- Conditions
- Barretts Esophagus, High Grade Dysplasia, Early Esophageal Adenocarcinoma
- Trial name
- ETMI (NCT00586989)
- Testing
- Upper endoscopy with biopsy
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
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