Clinical trials: Cervical Neoplasms
Differentiated Thyroid Cancer, Thyroid Cancer, Nonmedullary
IDEntification of New Predisposition Genes in Differentiated THYroid Cancer
The purpose of this research is to find new predisposition genes for differentiated thyroid cancer (DTC).
- Trial name
- IDENTHY-K (NCT05014698)
- Testing
- WGS
- Where
- 2 sites in France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Barretts Esophagus, High Grade Dysplasia
Endoscopic Tri-Modal Imaging in Patients With Barrett's Esophagus
This study is being done to determine if a new endoscope will help doctors identify pre-cancer or early cancer lesions in patients who have Barrett's esophagus.
- Conditions
- Barretts Esophagus, High Grade Dysplasia, Early Esophageal Adenocarcinoma
- Trial name
- ETMI (NCT00586989)
- Testing
- Upper endoscopy with biopsy
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Head and Neck Neoplasms
Study to Evaluate the Natural History of Head and Neck Cancer Precursors in Taiwan
Background: Cancer of the mouth and throat is one of the most common cancers in Taiwan. This cancer develops over several years, beginning as white or red patches in the mouth or throat that become growths.
- Trial name
- NCT02017288
- Where
- 4 sites in Taiwan
- Volunteers
- 3,576 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Cervical Cancer, CIN
Non-invasive Biomarker Discovery for Pre-cervical or/and Cervical Cancer--ACTN4 and Other Biomarkers in Menstrual Blood
The goal of this clinical trial is 1. To test the sensitivity and specificity of using ACTN4 from menstrual blood for the detection of pre-cervical or/and cervical cancer. 2.
- Trial name
- NCT06261879
- Testing
- Special sanitary pad
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- WomenX Biotech Limited
Cervical Cancer
Screen and Treat for Cervical Cancer Prevention
The study measures the impact of "screen-and-treat" on the prevalence of high-grade cervical intraepithelial neoplasia and cancer (CIN 2+).
- Trial name
- SAT (NCT00233727)
- Testing
- HPV DNA Testing + Cryosurgery, VIA + Cryosurgery
- Where
- South Africa
- Volunteers
- 7,123 people, healthy volunteers welcome
- Sponsor
- Columbia University
Breast Cancer, Thyroid Cancer
3-D Super Resolution Ultrasound Microvascular Imaging
This is a 3-arm single center study of 45 patients. These cohorts will include 15 breast patients scheduled to undergo a biopsy, and 15 thyroid patients scheduled to undergo fine needle aspiration, biopsy, or thyroidectomy that…
- Trial name
- NCT04136912
- Testing
- Definity, Acoustic Angiography
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cervical Cancer
HPV DNA Testing Through Mobile Mammography Unit
Invasive cervical cancer incidence and mortality can be dramatically reduced through early detection and treatment, but many women do not complete screening at recommended intervals.
- Trial name
- NCT03551028
- Testing
- HPV self collection
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Lung Cancer, Squamous Cell Carcinoma
An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037
Phase: Exploratory Study Objectives: To collect drug bio-distribution data, begin collection of baseline and tumor/background imaging data, acquire experience to improve study design and the conduct of future studies Design…
- Conditions
- Lung Cancer, Squamous Cell Carcinoma, Head and Neck Cancer, Hepatic Carcinoma
- Trial name
- VM4-037 (NCT00884520)
- Testing
- [F-18] VM4-037
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Siemens Molecular Imaging
Anal Carcinoma, Anal Condyloma
Study of Anal Cytologies in Patients With High Grade Cervical Intraepithelial Neoplasia (CIN II and III)
Cervical cancer is the third most frequent neoplasm in Brazilian women (estimated risk of 15.33 cases / 100,000 women by 2014), behind breast and colorectal cancer.
- Trial name
- NCT03241680
- Testing
- Search of anal citology alterations
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Cervical Cancer, Precancerous Condition
Spectroscopy in Diagnosing Dysplasia and Neoplasia in the Cervix in Women Undergoing Colposcopy
RATIONALE: New diagnostic procedures, such as spectroscopy, may be a less invasive way to check for dysplasia and neoplasia in the cervix.
- Trial name
- NCT00632190
- Testing
- fluorophotometry, colposcopic biopsy, colposcopy
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Nasopharyngeal Carcinoma (NPC)
Individualized Neck Cervical Irradiation Prophylaxis Trial of NPC
Based on the pattern of nasopharyngeal carcinoma cervical lymph node metastasis, which typically follows a sequential downward spread with rare skip metastases and a tendency for ipsilateral neck involvement, and in accordance…
- Trial name
- INCIPT-NPC (NCT07303023)
- Testing
- Individualized Neck Irradiation, Standard Neck Irradiation
- Where
- 6 sites in China
- Volunteers
- 462 people, healthy volunteers welcome
- Sponsor
- Fudan University
Barrett's Esophagus, Esophageal Cancer
TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)
A prospective outcomes study in patients with and esophageal cancer (EAC) and Barrett's esophagus (BE) associated neoplasia being evaluated for endoscopic eradication therapy (EET).
- Trial name
- NCT02634645
- Testing
- Endoscopic eradication therapies (EET), Esophagectomy, Chemotherapy
- Where
- 4 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Nasopharyngeal Carcinoma
S-1 Combined With IMRT Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma
This study is a prospective phase II trial which is designed to evaluate the efficacy and safety of IMRT combined with S-1 CCRT for locally advanced NPC.
- Trial name
- NCT03668366
- Testing
- S-1
- Where
- China
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Fudan University
Human Papilloma Virus-Related Cervical Carcinoma
An Intervention Promoting HPV Vaccination in Safety-net Clinics
This randomized controlled trial is designed to evaluate whether a behavioral intervention that includes three components: 1) reminder letters and education materials delivered before the clinic visit, 2) telephone recalls after…
- Trial name
- NCT01729429
- Testing
- HPV brochure, recall, reminders, General Adolescent Vaccine Brochure
- Where
- 2 sites in United States
- Volunteers
- 831 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Cervical Cancer, Human Papillomavirus
Accuracy of Portable Colposcopy and HPV Genotypes Among HIV+ Women
This study will evaluate the effectiveness of portable colposcopy when compared to conventional colposcopy (25x magnification of the cervix, the gold standard) and Visualization Inspection with Acetic acid (VIA, with 1x…
- Conditions
- Cervical Cancer, Human Papillomavirus, Human Immunodeficiency Virus
- Trial name
- NCT02338141
- Testing
- Portable colposcopy (Cerviscope), Conventional colposcopy (Wallach Zoomscope)
- Where
- Haiti
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Duke University
Health Education
The Effects of Health Education About Human Papilloma Virus and Cervical Cancer Prevention on Knowledge, Attitudes, Beliefs and Behaviors
Aim: To determine the effects of health education about Human Papilloma Virus infection and cervical cancer prevention on knowledge, attitudes, beliefs and behaviors of adolescent girls and their mothers.
- Trial name
- NCT04113902
- Testing
- Health Education
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Esophageal Squamous Cell Carcinoma, Oligometastatic Disease
Anti-PD-1 Immunotherapy Combined With SBRT for Patients With Oligometastatic ESCC
The goal of this phase II clinical trial is to explore the efficacy and safety of anti-PD1 combined with stereotactic body radiation therapy (SBRT) for patients with oligometastatic esophageal squamous cell carcinoma.
- Trial name
- NCT05626569
- Testing
- PD-1 combined with SBRT
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Human Papillomavirus (HPV), Cervical Intraepithelial Neoplasia
Validation of a Lab-free Low-cost Screening Test for Prevention of Cervical Cancer
The purpose of this study is to validate Automated Visual Evaluation (AVE), specifically the CINFinder version developed by DL Analytics, a point-of-care screening and triage diagnostic tool for cervical cancer based on the…
- Conditions
- Human Papillomavirus (HPV), Cervical Intraepithelial Neoplasia, Uterine Cervical Neoplasms, Cervical Cancers
- Trial name
- OPTICS (NCT06815939)
- Testing
- HPV Test, EVA System, Visual Inspection with Acetic Acid (VIA)
- Where
- El Salvador
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- DL Analytics
Intestinal Microbiota, Vaginal Microbiota
Characteristics of Vaginal and Intestinal Microbiota and Cervical HPV Infection
There are different microbial communities on the surface of human body (skin, hair, nails, etc.) and in the cavity connected with the outside world.
- Conditions
- Intestinal Microbiota, Vaginal Microbiota, HPV Infection
- Trial name
- NCT05003505
- Testing
- Follow up
- Where
- 8 sites in China
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- Fujian Maternity and Child Health Hospital
Head and Neck Cancer
Diagnostic Aids for Detection and Diagnosis of Oral Cancer
The goal of this clinical study is to find out if certain instruments/devices, such as wide field fluorescence imaging point spectroscopy and/or brush cytology, can help health care providers find mouth cancer more quickly than a…
- Trial name
- NCT02251639
- Testing
- Questionnaire, POS + PS2 + VELscope, Oral Brush Biopsy
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
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