Clinical trials: Cervical Ripening
Missed Abortion
Buccal Versus Vaginal Misoprostol in Surgical Termination of the First Trimester Missed Abortion in Erbil
The purpose of this study is to determine the effectiveness of buccal misoprostol and comparing this with vaginal route of the same drug.
- Trial name
- NCT00892229
- Testing
- Misoprostol (given buccally), Misoprostol (given vaginally)
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Cervical Ripening, Unfavorable Cervix
Oxytocin vs Prostaglandins for Labor Induction of Women With an Unfavorable Cervix After 24h of Cervical Ripening
Twenty-two percent of deliveries in France are induced. In cases where labor is induced and cervix is unfavorable, cervical ripening prior oxytocin administration is advised in order to reduce the risk of cesarean delivery.
- Trial name
- OPIC (NCT04949633)
- Testing
- Prostaglandins, Oxytocin
- Where
- 14 sites in France
- Volunteers
- 1,494 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Labor, Induced, Cervical Ripening
Membrane Stripping for Cervical Ripening
The goal of this interventional study is to evaluate the effectiveness of membrane stripping in cervical ripening compared to double balloon catheter induction. The study population consists of women undergoing labor induction.
- Conditions
- Labor, Induced, Cervical Ripening, Balloon Induction, Membrane Stripping
- Trial name
- Stripping (NCT06591247)
- Testing
- Double Baloon Catheter, Membrane Stripping, PGE2
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Induction of Labor Affected Fetus / Newborn
Early Versus Late Amniotomy Following EAB Cervical Ripening
The objective of this study is to investigate the course of labor in early versus late amniotomy following balloon cervical ripening in women undergoing term induction of labor stratified by parity.
- Trial name
- NCT04216628
- Testing
- Amniotomy
- Where
- Israel
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Labor, Induced, Cervical Ripening
Labor Induction With a Combined Method (Pharmacologic and Mechanical): Randomized Controlled Trial
Labor induction is a common pregnancy procedure worldwide. Both mechanical and pharmacologic agents are used for induction of labor. These agents reduce the incidence of cesarean delivery in women undergoing induction.
- Trial name
- NCT03928600
- Testing
- Cervical Foley combined with Misoprostol, Dinoprostone 10mg insert OR, Misoprostol
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Cervical Ripening and Induction of Labor
Cervical Ripening: A Comparison Between Intravaginal Misoprostol Tablet and Intracervical Foley's Catheter and Subsequent Induction of Labor, Safety and Efficacy in Federal Teaching Hospital Abakaliki, Ebonyi State, Nigeria.
The aim of this study is to compare the effectiveness and safety of Foley's catheter and misoprostol in cervical ripening.
- Trial name
- NCT02574338
- Testing
- Foley's Catheter, prostaglandin E1 analogue
- Where
- Nigeria
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Nwali Matthew Igwe
Induction of Labor, Cervical Ripening
Combined Nipple Stimulation and Foley Balloon for Cervical Ripening
Labor induction rates have increased substantially worldwide, and successful cervical ripening remains a key determinant of induction outcomes.
- Trial name
- NCT07317674
- Testing
- Foley balloon catheter with nipple stimulation, Mechanical cervical ripening with Foley catheter
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Induction of Labor Affected Fetus / Newborn, Cervical Ripening
Patient Satisfaction During Outpatient Versus Inpatient Foley Catheter Induction of Labor
Labor induction is one of the most common obstetric procedures performed in the U.S. In 2012, the last year for which data is available, 23.7% of all deliveries were the result of inductions.
- Conditions
- Induction of Labor Affected Fetus / Newborn, Cervical Ripening, Patient Satisfaction
- Trial name
- NCT02975167
- Testing
- Outpatient Cervical Ripening, Inpatient Cervical Ripening, Foley catheter placement
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Labour,Induced
Oral Misoprostol Solution in Labor Induction
This study compares safety and efficacy between repetitive hourly dose of oral misoprostol and two hourly dose oral regimens for cervical ripening and labor induction.
- Trial name
- NCT03927807
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Labor; Forced or Induced, Affecting Fetus or Newborn, Pregnancy
A Comparison of Oral Misoprostol and Vaginal Misoprostol for Cervical Ripening and Induction of Labor
The purpose of this study is to study if misoprostol administered orally is at least as effective as misoprostol administered vaginally for cervical ripening and the induction of labor.
- Trial name
- NCT02777190
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Pregnancy
Patient Satisfaction of Cervical Ripening in an Outpatient Setting
This study examines whether outpatient pre-induction cervical ripening improves patient satisfaction and is safe and effective.
- Trial name
- NCT01605474
- Testing
- Patient discharged home after foley bulb placement., Inpatient
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Induction of Labor
Cervical Ripening Balloon for 12 Hours vs. 1 Hour.
The aim of this study is a comparison of induction of labor with a cervical ripening balloon left in place for one hour compared to twelve hours. The primary outcome is time to delivery.
- Trial name
- NCT05922111
- Testing
- cervical ripening balloon for one hour, cervical ripening balloon for twelve hours
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Cervical Ripening, Induction of Labor
Study of the Effectiveness of Cervical Ripening Balloon With and Without Oxytocin
Study Purpose: The purpose of this study is to determine the optimal method for induction of labor in multiparous women who present with an unfavorable cervix.
- Conditions
- Cervical Ripening, Induction of Labor, Multiparity
- Trial name
- NCT03138252
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Induction of Labor Affected Fetus / Newborn
Dilapan-S® for Induction of Labor The Feasibility Study
This is a prospective feasibility study to investigate Dilapan-S® as an outpatient method of cervical ripening in low risk pregnancies >=39 weeks.
- Trial name
- DILATE (NCT04521062)
- Testing
- Dilapan S
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Induction of Labor, Cesarean
A Prospective Comparative Study of Induction of Labor With a Cervical Ripening Double Balloon vs Foley Catheter
Hypothesis: The induction of labor in patients with unfavorable Bishop score is a challenging obstetrical process, and may be influenced or complicated by the cervical ripening method used.
- Conditions
- Induction of Labor, Cesarean, Endometritis
- Trial name
- NCT00501033
- Testing
- Mechanical induction of labor, Double Balloon, Foley Catheter
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Unfavorable Cervix, Cervical Ripening
Combined Foley Catheter Balloon and PGE2 Vaginal Ovule for Induction of Labor at Term: A Randomized Study
This study evaluates the addition of transcervical Foley catheter balloon and vaginal prostaglandin E2 in induction of labor at term.
- Trial name
- NCT02861079
- Testing
- Foley catheter, PGE2
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Induced Labor, Cervical Ripening
Safety and Feasibility of the INGA Sensor System for Fetal and Uterine Monitoring During Cervical Ripening
The goal of this clinical trial is to learn about the safety and performance of the INGA Sensor System when used with the INGA balloon catheter during cervical ripening for labor induction in pregnant individuals at term.
- Conditions
- Induced Labor, Cervical Ripening, Cervical Ripening and Induction of Labor, Balloon Catheter for Labor Induction
- Trial name
- INGA-SENPe (NCT07846111)
- Testing
- Cervical ripening, labor Induction, uterus and fetal monitoring
- Where
- Estonia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Aalto University
Cervical Ripening
Misoprostol Versus Effox as Cervical Ripening Agent Prior Surgical Evacuation
Ninety healthy pregnant women candidate for surgical evacuation after confirming 1st trimester pregnancy loss were enrolled in the study.
- Trial name
- NCT02738177
- Testing
- Misoprostol, Isosorbide-5-mononitrate, misoprostol and Isosorbide-5-mononitrate
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy Outcome
Foley Balloon Study for Cervical Ripening - Cost Comparison Between Outpatient and Inpatient Cervical Ripening
The objective of this study is to determine the impact of outpatient cervical ripening with transcervical balloon placement for induction of labor at term on the length and cost of inpatient hospitalization when compared to…
- Trial name
- Balloon (NCT05506631)
- Testing
- Outpatient Foley balloon placement, Inpatient Foley Balloon placement
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Lehigh Valley Hospital
Induced Vaginal Delivery, Induced; Birth
Outpatient Transcervical Balloon For Induction of Labor
The goal of this randomized control trial is to compare outpatient transcervical foley balloon to inpatient vaginal misoprostol in pregnant women for cervical ripening. The main questions it aims to answer are: 1.
- Trial name
- NCT05798728
- Testing
- Outpatient transcervical foley balloon, Inpatient Vaginal Misoprostol
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hurley Medical Center