Clinical trials: Cessation, Smoking
Tobacco Dependence
Tobacco Intervention in Buprenorphine Treatment
Drug addiction treatment patients, including those in treatment for opioid dependence, have a high rate of tobacco dependence, especially cigarette smoking.
- Trial name
- IBIS (NCT01350011)
- Testing
- Innovative System, Standard Treatment Control (STC)
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking, Pregnancy
Effectiveness of Nicotine Replacement Therapy in Reducing the Risk of Nicotine Exposure in Pregnant Minority Smokers
This study will compare the effectiveness of counseling plus use of a nicotine patch with counseling alone for helping pregnant women quit smoking.
- Trial name
- NCT00341432
- Testing
- Nicotine Replacement Therapy
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Smoking
Genetic Differences in Limbic Activation Associated With Nicotine Withdrawal
Objectives: To evaluate neural correlates associated with emotional processing during nicotine withdrawal preferentially involving the amygdala and associated areas within the corticolimbic and mesolimbic circuitry.
- Trial name
- NCT00664404
- Testing
- Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Smoking
Smartphone Application for Smoking Cessation
The purpose of this study is to test the effectiveness of a smartphone application for smoking cessation in smokers ages 18 to 65 years.
- Trial name
- NCT02134509
- Testing
- Experimental App, Active Comparator App
- Where
- United States
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking, Overweight
The Effect of a High Protein Diet Versus a Low Fat Diet on Body Weight After Smoking Cessation
The purpose of this study is to determine whether subjects following a high protein diet will gain less in weight after smoking cessation compared to subjects following a low fat diet due to the effects of protein on metabolic…
- Conditions
- Smoking, Overweight, Obesity
- Trial name
- NCT01069458
- Testing
- The high protein diet group and the low fat diet group
- Where
- Norway
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Tobacco Use Disorder
Smoking Cessation Behavioral Treatment Study
The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT).
- Trial name
- NCT03948893
- Testing
- Mindfulness-Oriented Recovery Enhancement (MORE), Cognitive Behavioral Therapy (CBT)
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Vaping, Cessation, Tobacco
Text Message Quit Vaping Intervention for Adolescents
This research study, conducted by Truth Initiative, will help us learn how text messaging can help adolescents between 13 and 17 years of age quit vaping.
- Trial name
- NCT04919590
- Testing
- This is Quitting, Assessment only control, Waitlist control
- Where
- United States
- Volunteers
- 1,681 people, healthy volunteers welcome
- Sponsor
- Truth Initiative
Smoking Cessation
Developing Empowering Smoking Cessation
Problem: Despite encouraging use declines in the U.S. population, tobacco is still a leading cause of preventable disease and death.
- Trial name
- ECHO (NCT06602076)
- Testing
- ECHO (Empowering Our Community & Health Outcomes)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Initial Efficacy of Quit Line, Efficacy of Secondary Reengagement Intervention
Enhancing the Efficacy of Smoking Quit Line in the Military (AFIII Renewal)
This study is a randomized clinical trial designed to measure the effectiveness of three QL interventions for smokers who failed to quit an initial smoking cessation intervention, but remain motivated to quit smoking.
- Trial name
- Freedom (NCT02201810)
- Testing
- Rate reduction intervention, Recycling Group, Choice Group
- Where
- United States
- Volunteers
- 614 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Smoking Cessation, Pregnancy Related
Cash Payment and Counseling During Pregnancy
Smoking during pregnancy has harmful effects on both mother and unborn child. Studies have shown that small rewards can help smokers to quit.
- Conditions
- Smoking Cessation, Pregnancy Related, Incentives
- Trial name
- MARS (NCT04572178)
- Testing
- Cash payment and brief behavioral counseling
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Smoking Cessation
Pharmacological Aids for Interactive Smoking Cessation
There is an important need for effective smoking cessation programs that both (a) promote the effective use of pharmacological aids, such as nicotine replacement products and bupropion, and (b) provide cognitive-behavioral…
- Trial name
- NRT_2 (NCT02329249)
- Testing
- Smokefree Partners: 21 Days to Freedom, Wait-List Control
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Oregon Center for Applied Science, Inc.
Smoking
A Study to Investigate a Research Drug as an Aid for Smoking Cessation in Chronic Cigarette Smokers (0364-007)
The purpose of this study is to evaluate the safety and tolerability of an investigational drug that may help individuals to stop smoking.
- Trial name
- NCT00109135
- Testing
- taranabant
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Smoking Cessation
Countering Young Adult Tobacco Marketing in Bars
The goal of the study is to implement and evaluate interventions to decrease smoking among young adults attending bars and nightclubs.
- Trial name
- NCT01686178
- Testing
- Anti-smoking social marketing campaign
- Where
- United States
- Volunteers
- 17,422 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Nicotine Dependence, E-Cig Use
Research and Innovation to Stop E-cigarette/Vaping in Young Adults
The aim of this study is to test intervention components to help young adults quit vaping. A 2x2 factorial design will be used where all participants receive quitline-delivered behavioral phone counseling, and components to be…
- Trial name
- (RISE) (NCT04974580)
- Testing
- Nicotine patch, Phone Counseling, Digital Coaching
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Smoking Cessation
Rural COPD E-Visit Study
The purpose of this study is to evaluate an electronic visit (e-visit) for COPD screening and for quitting smoking. Participants will be randomly assigned to receive either the smoking cessation e-visit or not.
- Trial name
- NCT06236347
- Testing
- Smoking cessation e-visit, Treatment as usual
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking Cessation, Smoking, Cigarette
Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia
The goal of this clinical trial is to evaluate the effectiveness and implementation of a pharmacist-delivered MTM (medication therapy management) approach, called QuitAid, to quitting cigarette smoking in rural Appalachia.
- Conditions
- Smoking Cessation, Smoking, Cigarette, Smoking Reduction, Smoking
- Trial name
- NCT05660525
- Testing
- 4 weeks of Nicotine lozenge, 8 weeks of Nicotine Replacement Therapy Patch, QuitAid
- Where
- United States
- Volunteers
- 768 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Smoking, Smoking Cessation
BRP1802 Smoking Abstinence Study
A single-center study designed to evaluate changes in short-term biomarkers of potential harm (BoPH) in healthy adult cigarette smokers of two age groups (Group A: 24-34 years; Group B: 35-60 years) during 14 days of smoking…
- Conditions
- Smoking, Smoking Cessation, Tobacco Use
- Trial name
- NCT04979013
- Testing
- Smoking Abstinence
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Tobacco Use Cessation
Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)
The over-arching research question is: Does message (Advise) and referral approach (Refer) influence a patient's willingness to "opt-in" to receive a call from an Illinois Tobacco Quitline (ITQL) smoking cessation coach in…
- Trial name
- NCT04827420
- Testing
- Mi Quit Care
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Smoking Cessation, Smoking, Tobacco
Path2Quit Tobacco Intervention For African Americans
The purpose of this research is to study a smoking cessation program for adult smokers in Northeast Ohio. The study will also look at how different people respond to the program.
- Trial name
- NCT03524482
- Testing
- SmokeFreeText, Path2Quit
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Chronic Obstructive Pulmonary Disease
Endotoxin and Inflammatory Markers in Healthy Non-Smokers and Current Smokers Including Patients With Chronic Obstructive Pulmonary Disease (COPD)
The primary aim of this study is to investigate the effects of inhaled lipopolysaccharide endotoxin (LPS) on bronchial and alveolar exhaled nitric oxide (NO) and NO metabolites and other inflammatory markers and mediators in…
- Trial name
- NCT00159289
- Testing
- Inhalation of LPS
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London