Clinical trials: Chemical Peeling
Acne Vulgaris
Evaluation of Efficacy and Tolerance of Crystal Peel in the Treatment of Adults Presenting Facial Mild Acne
The goal of this interventional, confirmatory and post market study is to evaluate the efficacy and clinical performance of Crystal Peel in adults suffering mild facial acne vulgaris.
- Trial name
- NCT05821296
- Testing
- Crystal Peel
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Dermosciences France
Aging Disorder
EFFECTIVENESS AND SAFETY OF CREAM CONTAINING SPENT GRAIN WAX EXTRACT, ARGAN OIL, AND SHEA BUTTER POST-TRICHOLOROACETIC ACID 15% PEEL: RANDOMIZED, CONTROLLED, DOUBLE-BLIND, SPLIT-FACE CLINICAL TRIAL
Chemical peels are resurfacing procedures where chemical agent causes controlled exfoliation of the skin, followed by regeneration and remodelling of the epidermis and dermis layers.
- Trial name
- NCT06255431
- Testing
- Ezerra cream
- Where
- Indonesia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Melasma
Trichloroacetic Acid (TCA) Combined With Microdermabrasion in Treatment of Melasma
1. To detect the efficacy and safety of combined TCA and MDA in treating melasma. 2. To compare the efficacy and safety of using different TCA concentrations (15% \& 20%) alone and in combination with MDA in treatment of melasma.
- Trial name
- NCT04823520
- Testing
- TCA
- Volunteers
- 60 people
- Sponsor
- Assiut University
Skin Cancer
Chemical Peels and Fractional Laser on IGF-1 Levels in Skin
The purpose of this study is to evaluate the impact of fractional laser versus chemical peels on IGF-1 levels in skin.
- Trial name
- NCT03775031
- Testing
- Fractional Laser and Chemical Peel
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Melasma
Efficacy and Safety of 30% Salicylic Acid and 10% Nicotinamide Combined Therapy in Melasma
This prospective, randomized, placebo-controlled study evaluated the synergistic effects of 30% salicylic acid (SA) chemical peels and topical 10% nicotinamide (NAM) in 56 patients with moderate-to-severe melasma.
- Trial name
- NCT07062120
- Testing
- Nicotinamide(NAM)(10%), Supramolecular salicylic acid(SSA) (30%), Supramolecular salicylic acid simulator
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Photodamaged Skin
Placebo-Controlled Study Assessing the Use of a Novel Exfoliative Serum With A Chemical Peel to Improve Photodamage in Adults
This is a split-face, double-blind, placebo-controlled study assessing the use of a novel exfoliative serum with a chemical peel to improve photodamage in healthy female subjects between the ages of 30 and 65 years, inclusive…
- Trial name
- NCT05908825
- Testing
- Vitamin C with AHA Exfoliative Serum
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Austin Institute for Clinical Research
Melasma, Acne Scars - Mixed Atrophic and Hypertrophic
Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser
More than aesthetics, the search for orofacial harmonization treatments has increased when the negative emotional impact of some facial conditions such as melasma and acne scars is recognized.
- Conditions
- Melasma, Acne Scars - Mixed Atrophic and Hypertrophic, Resurfacing, Rejuvenation
- Trial name
- NCT07036302
- Testing
- 35% TCA combined with croton oil peel, Isolate 35% TCA peel, Erbium-YAG laser
- Where
- 2 sites in Brazil
- Volunteers
- 120 people
- Sponsor
- Jose Roberto Cortelli
Facial Photo Damage, Periocular Fine Wrinkles
A Trial of Skin Care Protocols for Facial Resurfacing
The aims of the Skin Product Assessment Research study were to (1) develop an infrastructure and process for industry-sponsored, Plastic Surgery Educational Foundation (PSEF) research in facial aesthetic surgery and (2) test the…
- Conditions
- Facial Photo Damage, Periocular Fine Wrinkles, Perioral Fine Wrinkles
- Trial name
- SPAR (NCT01113606)
- Testing
- Obagi New-Derm System, Standard of Care
- Where
- 9 sites in United States
- Sponsor
- The Plastic Surgery Foundation
Palmar and Plantar Erythema, Numbness of the Four Limbs
Traditional Chinese Medicine Treatment for Capecitabine-Related Hand-Foot Syndrome
This study is a prospective, single-center, randomized, parallel-group, open-label clinical trial titled "Intervention with the 'Xu Xue Tong Luo Traditional Chinese Medicine Compound for Capecitabine-Related Hand-Foot Syndrome."…
- Conditions
- Palmar and Plantar Erythema, Numbness of the Four Limbs, Pain in the Distal Extremities, Peeling of the Soles and Palms
- Trial name
- NCT07883642
- Testing
- Twelve-Ingredient Prepared Sichuan Aconite Hand and Foot Bath, Standard Basic Nursing Interventions
- Volunteers
- 7 people
- Sponsor
- Emeishan Hospital of Traditional Chinese Medicine
Photoaging
Effectivity of 1 Finger Tip Unit Compared to 2 Finger Tip Units 0.05% Tretinoin Cream
This clinical study will compare the efficacy of using one fingertip unit and two fingertip units of 0.05% before and after 30% trichloroacetic acid chemical peel procedure for facial skin rejuvenation in 35-60 years old female…
- Trial name
- NCT05004909
- Testing
- 0.05% Tretinoin
- Where
- Indonesia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Nonmelanoma Skin Cancer, Actinic Keratosis
Therapeutic Induction of Dermal Remodeling in Veterans to Prevent Actinic Neoplasia Caused by Chronic Environmental Exposure to Ultraviolet Radiation
The investigators' previous studies demonstrate geriatric subject skin responds differently to ultraviolet B (UVB) light compared to young subject skin, which contribute to increased rates of nonmelanoma skin cancer (NMSC) and…
- Trial name
- NCT07648407
- Testing
- Microneedling, Trichloroacetic acid peel
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- VA Office of Research and Development
Wrinkles
Lateral Canthal Rhytides With Medium Depth Chemical Peel With or Without Pretreatment With Botulinum Toxin A
This study is being done to find out if the use of botulinum toxin prior to a medium strength combination chemical peel (Jessner's peel followed by 35% Trichloroacetic acid peel) will improve the appearance of crow's feet…
- Trial name
- NCT01586819
- Testing
- Botulinum Toxin, Chemical Peel Only
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Loyola University
Photoaging, Lentigo
TCA 15% Chemical Peel for Improvement in Hand Lentigines
This study will evaluate the efficacy of the a 15% trichloroacetic acid + 3% glycolic acid peel combination for treatment of lentigines on the hands. This peel combination is sold over the counter.
- Trial name
- NCT05471947
- Testing
- 15% Trichloroacetic acid + 3% glycolic acid
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Main Line Center for Laser Surgery
Acanthosis Nigricans
Systemic and Topical Metformin Versus Glycolic Acid Peel for the Treatment of Acanthosis Nigricans
Acanthosis nigricans (AN) is a common dermatologic condition associated with insulin resistance and obesity. Existing treatment options often provide inconsistent results.
- Trial name
- MET-AN (NCT07751549)
- Testing
- systemic metformin, topical intervention, glycolic acid 70% peeling
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Tanta University
Rosacea
A Pilot Study Testing the Effects of Chemical Peels in Patients With Rosacea
The study is a prospective, randomized, one-site therapeutic trial of 15% trichloroacetic acid (TCA) and 30% salicylic acid peels for rosacea. Two peels will be applied topically 4 weeks apart, and the study will end in 12 weeks.
- Trial name
- NCT04889703
- Testing
- 15% Trichloroacetic acid peel, 30% Salicylic acid peel
- Sponsor
- University of Texas Southwestern Medical Center
Chemical Peeling
An Assessment of the Efficacy and Safety of Employing a Duosomal Chemical Peel for Aesthetic Enhancement in the Periocular and Facial Regions
This study will employ an experimental, prospective, longitudinal, and comparative before-and-after design. The objective is to assess the efficacy and safety of duosomal chemical peels as agents for enhancing the aesthetic…
- Trial name
- AESEDCPAEPFR (NCT07401342)
- Testing
- Duosomal chemical peel application
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Peeling Skin Syndrome
A Comparative Investigation of Efficacy and Complications in Light and Deep Chemical Peels
Chemical peeling involves applying substances to the skin to induce controlled damage, which promotes the regeneration of fresh skin cells and enhances the skin's appearance.
- Trial name
- NCT06749561
- Testing
- Group 1
- Where
- Pakistan
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Superior University
Substance Use Disorders (SUDs)
Cogito: A Turnkey Solution for Rapidly Developing, Evaluating, Deploying, and Scaling Digital Therapeutics
This is a research study to evaluate the usability of the Cogito digital therapeutics development platform. The Cogito platform is designed to allow researchers who are seeking to embed an evidence-based behavioral therapy into a…
- Trial name
- NCT07104396
- Testing
- Cogito digital therapeutics development platform
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Square2 Systems, Inc.
Acne Vulgaris
Combined Salicylic and Azaleic Acid Verus Trichloroacetic Acid 25% Peel in Treatment of Acne
Acne patients were included in this randomized controlled trial. Each patient received four treatment sessions two weeks apart. 20% azelaic acid combined with 20% salicylic acid were applied to the one side of the face while 25%…
- Trial name
- NCT03071549
- Testing
- Trichloroacetic acid peel, combined azaleic and salicylic acids
- Volunteers
- 34 people
- Sponsor
- Cairo University
Skin Manifestations
Effectiveness, Safety, and Cost Efficacy of Water (H2O) as a Substitute for Sodium Bicarbonate (NaHCO3) Plus Solution in Neutralization of Chemical Peeling Using 35% Glycolic Acid Solution
Chemical peeling is an applied procedure which creates controlled destruction of all layers of the epidermis or dermis, subsequently causes exfoliation followed by regeneration of layers with the final result of improved texture…
- Trial name
- NCT04154436
- Testing
- Sodium Bicarbonate (NaHCO3) Plus Solution, Water (H2o)
- Where
- Indonesia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia