Clinical trials: Chemotherapy Effects
Breast Neoplasms
Breast Cancer Long-term Outcome of Cardiac Dysfunction
The purpose of this study is to assess the prevalence of cardiac dysfunction and (undiagnosed) heart failure in women registered in general practice with a history of breast cancer who received chemotherapy and / or radiotherapy…
- Trial name
- BLOC (NCT01904331)
- Where
- Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Japanese Premenopausal Healthy Adult Women
A Food Effect Study of TAK-385 Final Formulation
The purpose of this study is to evaluate food effects on the pharmacokinetics of a single oral dose of TAK-385 in Japanese premenopausal healthy adult women.
- Trial name
- NCT02792062
- Testing
- TAK-385 40 mg
- Where
- Japan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Takeda
Sleep Disorder
Safety and Efficacy of Ramelteon in Healthy Subjects
The purpose of this study is to determine the phase-advance in circadian rhythms in healthy adults subjects taking ramelteon, once daily (QD).
- Trial name
- NCT00671190
- Testing
- Ramelteon
- Where
- 13 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Takeda
Effects of Chemotherapy
Ovarian Freezing Before Cancer Treatment
Women of reproductive age who will undergo cancer treatment may participate in a study to surgically remove ovarian tissue and store it, frozen, for their potential use in the future.
- Trial name
- NCT01057745
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Chordoma, Chemotherapy Effect
Apatinib Combined With Camrelizumab in Treating Participants With Advanced Chordoma
This phase II trial studies how well Camrelizumab combined with Apatinib work in treating participants with chordoma that has spread to other places in the body, which may interfere with the ability of tumor cells to grow and…
- Trial name
- NCT06140732
- Testing
- camrelizumab and apatinib
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Healthy Volunteers
Bioavailability and Effect of Food on TAK-385 Tablet Formulations in Healthy Participants
The purpose of this study is to evaluate the oral bioavailability of two new tablet formulations of TAK-385 (T4 Formulation B and T4 Formulation C) under fasted and fed conditions, relative the T2 Formulation tablet; and to…
- Trial name
- NCT02396147
- Testing
- TAK-385 T2 Formulation, TAK-385 T4 Formulation B, TAK-385 T4 Formulation C
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Takeda
Cancer, Nutrition Disorders
Co-designed Nutritional Training Program for Oncology Nurses in Vietnam
This study evaluates a co-designed nutritional training program for oncology nurses in Vietnam. The aim is to improve nurses' knowledge, confidence, and clinical practice in providing nutritional support for patients with cancer…
- Conditions
- Cancer, Nutrition Disorders, Chemotherapy-Related Symptoms
- Trial name
- NUTRI-NURSE-VN (NCT07566169)
- Testing
- Co-Designed Nutritional Training Program
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- VinUniversity
Periodontal Diseases, Chronic Periodontitis
Photodynamic Therapy During Supportive Periodontal Therapy
27 subjects on SPT, each with at least two residual pockets ≥5mm, were recruited for this randomised, split-mouth controlled trial, providing a total of 72 sites.
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Periodontal Attachment Loss
- Trial name
- NCT02666573
- Testing
- Fotosan 630, CMS Dental, Copenhagen, Denmark, Scaling and root planing
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Healthy Volunteers
A Single-Dose Positron Emission Tomography (PET) Study to Determine the Effect of TAK-041 on Amphetamine-Induced Dopamine Release in the Central Nervous System (CNS)
The purpose of this study is to determine brain penetration of single oral doses of TAK-041 and its effects on amphetamine-induced dopamine release in the Central Nervous System (CNS).
- Trial name
- NCT02959892
- Testing
- Amphetamine, TAK -041, [11C] (+)-4-propyl-(+)-4-propyl-9-hydroxynaphthoxazine (PHNO)
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Neurocrine Biosciences
Cancer, Adherence to Medication Regime
Mobile Application to Assist Adherence to Oral Anticancer Agents and Symptom Management
The use of oral anticancer agents (OAAs) in cancer treatment has increased especially in the last two decades. The use of mobile health technologies in the management of OAA can be beneficial in terms of treatment adherence and…
- Conditions
- Cancer, Adherence to Medication Regime, Symptom Management
- Trial name
- NCT04626830
- Testing
- Mobile Application Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Baskent University
Aortic Stenosis, Chemotherapy Induced Systolic Dysfunction
Fibrosis in Chronic and Delayed Myocardial Infarction
In this study the investigators aim to examine the role that fibrosis plays in heart conditions such as aortic stenosis , chemotherapy-induced cardiotoxicity and carcinoid syndrome .
- Conditions
- Aortic Stenosis, Chemotherapy Induced Systolic Dysfunction, Carcinoid Syndrome
- Trial name
- FCDMI (NCT05756608)
- Testing
- 68Ga-FAPI and 18F-AlF-FAPI PET-MR
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Quality of Life, Cancer
Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors
This project aims to explore, in depth, the burden of hearing loss and tinnitus on cancer survivors. Using semi-structured interviews, audiograms and a variety of validated questionnaires, the specific impact ototoxicity has on…
- Conditions
- Quality of Life, Cancer, Hearing Loss, Sensorineural, Tinnitus, Subjective
- Trial name
- NCT04281953
- Testing
- High frequency audiometry, Short-Form 36-Item Questionnaire (SF-36), Hearing handicap inventory for adults/elderly (HHIA/HHIE)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Oral Mucositis
Effect of Cold Application and Artificial Saliva in the Prevention of Chemotherapy-Induced Oral Mucositis
the Objectives of this clinical trial is : 1. To determine the effect of Cold Application for preventing of chemotherapy-Induced oral mucositis in cancer patients. 2.
- Trial name
- NCT07297472
- Testing
- cold application, Artificial Saliva
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karbala University
Chemotherapy Effect, Pain Cancer
Effects of Virtual Museum Visit on Pain, Fatigue, and Anxiety in Patients Receiving Chemotherapy
Symptom management is the most important aspect of clinical cancer care. Virtual reality-based interventions can be used to improve cancer patients' experiences with medical treatment, with their distraction-based effects.
- Conditions
- Chemotherapy Effect, Pain Cancer, Fatigue, Anxiety
- Trial name
- NCT06844695
- Testing
- Art Therapy (Virtual Museum Visit)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Colon Cancer, Chemotherapeutic-Induced Anemia
Intravenous Iron Infusion on Chemotherapy-induced Anemia
FOLFOX, the first-line regimen based on 5-FU and oxaliplatin, is adjuvant chemotherapy for pathologic stage II/III colorectal cancer patients.
- Trial name
- NCT05299411
- Testing
- iron (isomaltoside), Dried Ferrous Sulfate
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital