Clinical trials: Chemotherapy Symptoms
Non-small Cell Lung Cancer, Vomiting
Study Assessing Fosaprepitant in Advanced NSCLC Patients Treated With Carboplatin Based Chemotherapy
This study evaluates the addition of fosaprepitant to currently available antiemtic treatments of carboplatin chemotherapy-induced nausea and vomiting in advanced non-small cell lung cancer patients.
- Conditions
- Non-small Cell Lung Cancer, Vomiting, Nausea, Emesis
- Trial name
- NCT02407600
- Testing
- FOSAPREPITANT (Emend)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Ajeet Gajra
Colorectal Cancer, Metastatic Cancer
Second-look Surgery With or Without Intraperitoneal Chemotherapy in Treating Patients With Recurrent Colorectal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs in different ways may kill more tumor cells.
- Conditions
- Colorectal Cancer, Metastatic Cancer, Primary Peritoneal Cavity Cancer
- Trial name
- NCT00005944
- Testing
- chemotherapy, fluorouracil, leucovorin calcium
- Where
- 18 sites in Belgium, France
- Sponsor
- UNICANCER
Lung Neoplasms, Symptom Management
Construction and Feasibility Study of a Home-Based Intelligent Symptom Management Program for Lung Cancer Patients Receiving Combined Drug Therapy Based on Symptom Journey Profiling
The goal of this clinical trial is to develop and evaluate a home-based intelligent symptom management program based on symptom journey profiles for patients with lung cancer receiving combination drug therapy.
- Conditions
- Lung Neoplasms, Symptom Management, mHealth Intervention
- Trial name
- NCT07632703
- Testing
- Home-Based Intelligent Symptom Management Program for Lung Cancer Patients During Intermittent Periods of Combined Drug Therapy, routine care
- Volunteers
- 60 people
- Sponsor
- Feifei Huang
Breast Neoplasms, Lymphoma
Feasibility Study of Interleukin 1-Alpha With Ifosfamide, CBDCA, and Etoposide With Autologous Bone Marrow Transplant in Metastatic Carcinoma and Lymphoma
This is a phase I/II study of interleukin-1, G-CSF and high dose ICE chemotherapy with autologous bone marrow transplant in patients with relapsed breast, testicular and lymphoid cancers.
- Conditions
- Breast Neoplasms, Lymphoma, Neoplasm Metastasis, Testicular Neoplasms
- Trial name
- NCT00001270
- Testing
- interleukin-1
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- National Cancer Institute (NCI)
Nausea, Vomiting
Laser Acupuncture Against Nausea in Children
To investigate whether nonthermal low level laser acupuncture has beneficial effects on nausea and vomiting in children receiving highly emetogenic chemotherapy for a malignant solid tumor.
- Conditions
- Nausea, Vomiting, Cancer
- Trial name
- NCT00528554
- Testing
- laser acupuncture
- Where
- 2 sites in Germany
- Volunteers
- 25 people
- Sponsor
- University Children Hospital Homburg
Colorectal Neoplasm, Colorectal Cancer
Perioperative Systemic Therapy for Isolated Resectable Colorectal Peritoneal Metastases
This is a multicentre, open-label, parallel-group, phase II-III, superiority study that randomises patients with isolated resectable colorectal peritoneal metastases in a 1:1 ratio to receive either perioperative systemic therapy…
- Conditions
- Colorectal Neoplasm, Colorectal Cancer, Colorectal Neoplasms Malignant, Colorectal Carcinoma
- Trial name
- CAIRO6 (NCT02758951)
- Testing
- Perioperative systemic therapy, Perioperative CAPOX-bevacizumab, Perioperative FOLFOX-bevacizumab
- Where
- 9 sites in Belgium, Netherlands
- Volunteers
- 358 people
- Sponsor
- Koen Rovers
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia
Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia
This phase II trial studies the side effects and how well combination chemotherapy and ponatinib hydrochloride work in treating patients with acute lymphoblastic leukemia.
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia, Adult Acute Lymphoblastic Leukemia in Complete Remission, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
- Trial name
- NCT01424982
- Testing
- Cyclophosphamide, Cytarabine, Dexamethasone
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- M.D. Anderson Cancer Center
Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy
Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes
This phase II trial studies the effect of adding pomalidomide to usual chemotherapy treatment (daunorubicin and cytarabine liposome) in treating patients with newly diagnosed acute leukemia with myelodysplastic syndrome-related…
- Conditions
- Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, Acute Myeloid Leukemia With Multilineage Dysplasia, Chronic Myelomonocytic Leukemia
- Trial name
- NCT04802161
- Testing
- Biospecimen Collection, Bone Marrow Aspiration and Biopsy, Liposome-encapsulated Daunorubicin-Cytarabine
- Where
- 11 sites in United States
- Volunteers
- 49 people
- Sponsor
- National Cancer Institute (NCI)
Peripheral Nervous System Diseases, Pain Management
Self-Guided Online Cognitive Behavioral Strategies for Chemotherapy-Induced Peripheral Neuropathy
The purpose of this pilot randomized wait-list controlled trial is to test the efficacy of an online cognitive behavioral pain management website called Proactive Self-Management Program for Effects of Cancer Treatment (PROPSECT)…
- Conditions
- Peripheral Nervous System Diseases, Pain Management, Self Management
- Trial name
- SONICS (NCT02760654)
- Testing
- Proactive Self Management Program for Effects of Cancer Treatment
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Chemotherapy-induced Peripheral Neuropathy, Onychodystrophy
CIPN-prevention Trial Evaluating the Efficacy of Hand-cooling and Hand-compression
The POLAR study is a monocentric, prospective, randomized, 2-arm study designed to evaluate the effectiveness of compression or hypothermia in preventing higher-grade chemotherapy-induced peripheral neuropathy (CIPN) (Grade > 1…
- Trial name
- POLAR (NCT06541769)
- Testing
- Limb hypothermia, Limb compression
- Where
- Germany
- Volunteers
- 122 people
- Sponsor
- University Hospital Heidelberg
Overactive Bladder, Lower Urinary Tract Symptoms
Combined Behavioral and Drug Treatment of Overactive Bladder in Men
The primary aim of this project is to evaluate the effectiveness of combined behavioral + drug therapy compared to behavioral treatment alone and drug therapy alone as a way to improve outcomes in the treatment of OAB symptoms in…
- Trial name
- COBALT (NCT01175382)
- Testing
- Behavioral training, Tolterodine + tamsulosin, Combined Behavioral + Drug Therapy
- Where
- 3 sites in United States
- Volunteers
- 204 people
- Sponsor
- University of Alabama at Birmingham
Lung Cancer
Effect on the Nutritional and Inflammatory Status of Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA)- Containing Supplement in Patients With Advanced Lung Cancer
Background: A frequent manifestation of advanced lung cancer is malnutrition, timely identification and treatment of which can lead to improved patient quality of life, response rate to chemotherapy and survival.
- Trial name
- NCT01048970
- Testing
- Nutritional Assessment, EPA-DHA arm
- Where
- 2 sites in Mexico
- Volunteers
- 120 people
- Sponsor
- National Institute of Cancerología
Gastrointestinal Neoplasms, Chemotherapy-induced Nausea and Vomiting
Aprepitant Triple Therapy for the Prevention of CINV in Nondrinking and Young Women Who Received Moderately Emetogenic Chemotherapy
The purpose of this study is to study whether adding Aprepitant to Palonosetron and dexamethasone can further prevent the incidence and severity of nausea and vomiting caused by FOLFIRI or FOLFOX chemotherapy regimen among…
- Trial name
- CINV (NCT03674294)
- Testing
- Aprepitant, Palonosetron, Dexamethasone
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Sun Yat-sen University
Chemotherapy-Induced Nausea and Vomiting
An Efficacy and Safety Study of Palonosetron in Preventing Chemotherapy-Induced Nausea and Vomiting (CINV) in the Chinese Cancer Patients
This clinical study was designed to demonstrate that a single, intravenous dose of palonosetron 0.25 mg was not inferior to granisetron 3 mg in preventing acute and delayed CINV and was also well tolerated in the Chinese cancer…
- Trial name
- NCT00666783
- Testing
- palonosetron, Granisetron
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Xijing Hospital
Non-Small Cell Lung Cancer
Docetaxel & Oxaliplatin in Combination With Bevacizumab as First-Line Treatment in Subjects With Non-Small Cell Lung Cancer (NSCLC)
The purpose of this study was to see how well three investigational drugs worked together in preventing progression of the disease.
- Trial name
- NCT00356122
- Testing
- Docetaxel, Oxaliplatin, Bevacizumab
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Sanofi
Anorexia, Weight Changes
Megestrol Acetate in Treating Weight Loss or Anorexia in Young Patients With Malignancies Who Are Undergoing Radiation Therapy and/or Chemotherapy
RATIONALE: Megestrol acetate may help improve appetite and lessen weight loss caused by cancer. PURPOSE: This clinical trial studies megestrol acetate in treating weight loss or anorexia in young patients with malignancies who…
- Trial name
- NCT01200602
- Testing
- megestrol acetate, clinical observation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Recurrent or Metastatic Breast Cancer
A Phase III Study of SYS6010 Versus Chemotherapy in HER2-Negative, EGFR-Positive Recurrent or Metastatic Breast Cancer
This study is a multicenter, randomized, open-label, parallel-control Phase III clinical trial enrolling patients with unresectable HER2-negative, EGFR-positive recurrent/metastatic breast cancer who have previously failed first…
- Trial name
- NCT07406542
- Testing
- SYS6010, Investigator's Choice of Chemotherapy (eribulin, capecitabine, gemcitabine, or vinorelbine)
- Volunteers
- 400 people
- Sponsor
- CSPC Megalith Biopharmaceutical Co.,Ltd.
Prosthesis Survival
A Phase III Study of Nimotuzumab Plus Concurrent Chemoradiotherapy in Loco-regional Esophageal Squamous Cell Carcinoma
Esophageal cancer is the sixth leading cause of cancer death in worldwide. Over the past 2 decades, well-designed clinical trials have documented the clinical benefits of combination of chemotherapy and radiation for localized…
- Trial name
- NCT02409186
- Testing
- Nimotuzumab, radiotherapy, chemoradiotherapy Paclitaxel
- Where
- 14 sites in China
- Volunteers
- 200 people
- Sponsor
- Shandong Cancer Hospital and Institute
Children, Chemotherapy-induced Nausea and Vomiting
Stimulation of Acupuncture Points by Athermic Laser Therapy for the Prevention of Chemotherapy Induced Nausea and Vomiting in Children
Poor control of chemotherapy-induced nausea and vomiting has a major clinical and psychological impact in patients treated with chemotherapy.
- Conditions
- Children, Chemotherapy-induced Nausea and Vomiting, Malignant Tumor
- Trial name
- NAUVOLA (NCT03354741)
- Testing
- laser therapy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Invasive Breast Cancer, Chemotherapeutic Toxicity
Prophylactic Gabapentin for Taxane-Induced Arthralgia and Myalgia Syndrome in Breast Cancer Patients Undergoing Adjuvant Chemotherapy
Taxane-induced arthralgia and myalgia syndrome (TAMS) is one of the most common side effects of taxane chemotherapy. This prospective randomized controlled trial will evaluate the efficacy of gabapentin administered…
- Conditions
- Invasive Breast Cancer, Chemotherapeutic Toxicity, Myalgia, Arthralgia
- Trial name
- NCT03566394
- Testing
- Gabapentin 300mg
- Volunteers
- 46 people
- Sponsor
- British Columbia Cancer Agency
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.