Clinical trials: Chest CT Scan
Lung Cancer
Positron Emission Tomography (PET)/Computed Tomography (CT) and Roentgen in Lung Cancer: Evaluation of Patients in General Practice
The prognosis of lung cancer depends much on the stage of the disease at the time of diagnosis. Only 16 % of lung cancer can be offered curative intended surgery.
- Trial name
- PROLOG (NCT00675168)
- Testing
- PET/CT (low-dose)
- Where
- 3 sites in Denmark
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Pneumonia
Screening for Pneumonia: A Comparison of Ultra Low Dose Chest CT [ULD-CT] and Conventional Chest Radiography [CXR]
The ULTRACHEST study will be a prospective clinical diagnostic performance study with primary objective to establish device diagnostic clinical performance of Ultra Low Dose CT (ULD-CT) in order to prove it is more accurate in…
- Trial name
- ULTRACHEST (NCT03140163)
- Testing
- ULD-CT, CXR
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Smoke Inhalation, Exposure, Inhalation
Lung Cancer Screening CT for Firefighters
Firefighters are at increased risk for cancer due to exposure to carcinogenic substances. Current lung cancer screening guidelines are predominantly based on smoking history and do not take into account high risk occupational…
- Conditions
- Smoke Inhalation, Exposure, Inhalation, Exposure to Pollution, Exposure Occupational
- Trial name
- NCT06836414
- Testing
- Low-dose Computerized tomography (CT) of Chest, Questionnaires, Medical History
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Lung Cancer
The DANTE Trial. A Randomized Study on Lung Cancer Screening With Low-Dose Spiral Computed Tomography
High survival rates have been reported for screen-detected Stage I lung cancer patients, but there are concerns about the potential biases of uncontrolled studies.
- Trial name
- NCT00420862
- Testing
- Spiral Computed Tomography
- Where
- Italy
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Volunteer
Clinical Study of Spectral CT
This study will prospective enroll 80 subjects to evaluate the comparison of image quality, proportion of high-quality images, and image noise between the Spectral Precise Image (SPI) intelligent denoising for low-dose scans on…
- Trial name
- NCT07759050
- Testing
- CT Radiation Scan
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Cardiopulmonary Resuscitation, Hand Position
Optimum Hand Position During Cardiopulmonary Resuscitation
The almost evidences of the optimal hand position during compression had been based on chest computed tomography (CT) or chest plain films of patients for investigating the effective location for compressing the left ventricle of…
- Trial name
- NCT02715180
- Testing
- low dose chest computed tomography
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Lung Cancer, Cardiovascular Disease (CVD)
Optimised Lung Cancer Screening to Prevent Cardiovascular and Pulmonary Diseases Coupled With Primary Prevention
This project aims to implement a health prevention program for smokers or former smokers including early detection of lung cancer, cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD).
- Conditions
- Lung Cancer, Cardiovascular Disease (CVD), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SMAC-1 (NCT04315766)
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Coronary Artery Disease, Coronary Artery Stenosis Stent
Deep Learning CAD Screening on Chest CT
Coronary artery disease (CAD) is one of the leading causes of death worldwide. Many people have early atherosclerosis without symptoms, and some may develop significant coronary stenosis before any warning signs appear.
- Trial name
- CAD-AI (NCT07181512)
- Testing
- Deep Learning Analysis of Non-contrast Chest CT
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yifan Guo
Lung Cancer
Implementing Fragmentomics Into Real World Screening IntervenTions to Evaluate Clinical Utility Among Individuals With Elevated Risk for Lung Cancer
The purpose of this study is to determine whether availability of DNA Evaluation of Fragments for Early Interception (DELFI) Lung Cancer Screening Test, FirstLook™ to practicing physicians affects overall lung cancer screening…
- Trial name
- FIRSTLUNG (NCT06145750)
- Testing
- Ability to order FirstLook™, Continuing Medical Education for Lung Cancer
- Where
- 3 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Delfi Diagnostics Inc.
Lung Cancer, Blood Biomarkers
AI for Lung Cancer Risk Definition in Computed Tomography Screening Programs
Low-dose computed tomography (LDCT) lung cancer (LC) screening can reduce mortality among heavy smokers, but there is a critical need to better identify people at higher risk and to reduce harms related to management of benign…
- Trial name
- NCT06320184
- Testing
- Artificial Intelligence risk model
- Where
- Italy
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Electric Impedance, Respiratory Function Tests
Prediction of COPD Severity Using Electrical Impedance Tomography
The purpose of this study is to predict the CT visual score of emphysema with EIT-based parameters, in order to provide a non-invasive and convenient method for the evaluation of lung structure and physiological and pathological…
- Conditions
- Electric Impedance, Respiratory Function Tests, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT06359145
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Lung Cancer
Early Detection of Lung Cancer in a High-Risk Population Defined by PFT, Biomarkers, and CT Scanning
Lung cancer is the number one cancer killer in Kentucky and has a very high incidence within the 5th Congressional District of Kentucky (110.8 cases per 100,000 in period 1996-2000).
- Trial name
- NCT00596310
- Testing
- CT
- Where
- 4 sites in United States
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Susanne Arnold
Lung Cancer
Centralized Screening Unit (CSU) at Montefiore-Einstein
This study proposes to increase Lung-cancer screening (LCS) in the Bronx, New York. Despite strong evidence that Lung-cancer screening (LCS) can reduce Lung cancer (LCa) deaths, low-dose computed tomography (LDCT) referral rates…
- Trial name
- NCT06284408
- Testing
- Centralized Screening Unit Implementation
- Where
- United States
- Volunteers
- 9,460 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Pulmonary Nodules
A Prospective Cohort Study of Chinese Patients With Pulmonary Nodules: Prediction of Lung Cancer Using Noninvasive Biomarkers
The broad goals of this study is to identify changes in genomic landscape during transition from stage 0 to stage 1 lung cancer.
- Trial name
- NCT04462185
- Testing
- A genomic and transcriptomic landscape analysis
- Where
- 6 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- AnchorDx Medical Co., Ltd.
Coronary Angiography, Chest Pain
Coronary Computed Tomography for Systematic Triage of Acute Chest Pain Patients to Treatment (CT-STAT)
This is a prospective, randomized multicenter trial comparing MSCT to standard of care (SOC) diagnostic treatment in the triage of Emergency Department (ED) low to intermediate risk chest pain patients.
- Trial name
- CTSTAT (NCT00468325)
- Testing
- Multi-slice computed tomography, Rest-stress Nuclear Myocardial Perfusion Imaging
- Where
- 16 sites in United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Breast Cancer
Characterization of Breast Masses Incidentally Detected on Chest CT
Although Computed tomography (CT) is not routinely used to evaluate beast masses, It is common to discover Incidental breast lesions on chest CT.
- Trial name
- NCT02755779
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel Aviv Medical Center
Adrenal Incidentalomas, Thoracic CT-scan
Artificial Intelligence Used in Screening Adrenal Nodules
By collecting chest low-dose spiral CT plain scan images, extracting effective features from the adrenal gland regions, training and validating an artificial intelligence-based automatic diagnostic algorithm for adrenal nodules…
- Trial name
- NCT07198152
- Testing
- None intervention
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Lung Neoplasms, Computed Tomography
Methods of Computed Tomography Screening and Management of Lung Cancer
European lung cancer screening studies using computed tomography (CT) have shown that a management protocol based on measuring lung nodule volume and volume doubling time (VDT) is more specific for early lung cancer detection…
- Conditions
- Lung Neoplasms, Computed Tomography, Mass Screening, Lung Nodules
- Trial name
- NCT03992833
- Testing
- lung cancer screening
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Renal Cell Carcinoma
Yorkshire Kidney Screening Trial
Kidney cancer is the 8th most common cancer in Yorkshire. It has a poor survival rate, with only 6 out of 10 patients diagnosed with kidney cancer still alive after 5 years.
- Trial name
- YKST (NCT05005195)
- Testing
- Low dose abdominal computed tomography scan
- Where
- United Kingdom
- Volunteers
- 5,850 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Lung Cancer
Early Stage Lung Cancer Screening With Low-dose Computed Tomographic
The present study is a randomized controlled trial of LDCT screening for lung cancer versus usual care. 6000 high-risk subjects (age 45-70) were recruited and randomized to the Active arm (Baseline + 2 biennial repeated LDCT…
- Trial name
- NCT02898441
- Testing
- Low Dose Computed Tomography
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Chest Hospital