Clinical trials: Chest CT Scan
Pneumonia; Pulmonary Infection
A Multicenter Randomized Trial of CT-Based AI Decision Support for Early Pneumonia Care
Adults hospitalized with pneumonia who need new or increased oxygen support or have defined immunocompromise will be assigned to usual care with or without access to a CT-based AI report.
- Trial name
- NCT07895290
- Testing
- CT-Based AI Decision Support for Pneumonia
- Where
- China
- Volunteers
- 4,800 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lung Cancer
The DANTE Trial. A Randomized Study on Lung Cancer Screening With Low-Dose Spiral Computed Tomography
High survival rates have been reported for screen-detected Stage I lung cancer patients, but there are concerns about the potential biases of uncontrolled studies.
- Trial name
- NCT00420862
- Testing
- Spiral Computed Tomography
- Where
- Italy
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Stable Angina, Coronary Artery Disease
CCTA, CACS and ECG Stress Testing in Patients With Suspected CAD: Precision Phenotyping and Financial Evaluation
The "DATASET-PRECISE", a 3-arm parallel randomized study, aims to provide new insights in risk stratification of patients with suspected CAD in the Greek population.
- Conditions
- Stable Angina, Coronary Artery Disease, Atherosclerosis, Coronary Artery Calcification
- Trial name
- DATASET (NCT04424121)
- Testing
- CCTA
- Where
- 3 sites in Greece
- Volunteers
- 900 people
- Sponsor
- Aristotle University Of Thessaloniki
Aging
Effect of Ageing on Airway Remodeling
The aim of the study is to investigate the relationship between aging and morphological changes in the lung. 120 consecutive healthy volunteers over 60 years will be enrolled for this trial.
- Trial name
- NCT01230879
- Testing
- EFR and TDM
- Where
- France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Acute Coronary Syndrome, Myocardial Infarction
Rule Out Myocardial Infarction by Computer Assisted Tomography
The goal of this research is to determine noninvasively whether detection of coronary stenosis and plaque by multidetector computed tomography (MDCT) in patients with acute chest pain suspected of acute coronary syndrome (ACS)…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Unstable Angina Pectoris
- Trial name
- ROMICAT (NCT00990262)
- Testing
- Cardiac Computed Tomography
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- Massachusetts General Hospital
Lung Cancer
The Role of 18F-FDG-PET/CT Scan in Lung Cancer Patients
Describe strengths and limitations of FDG PET/CT for staging. Evaluate the utility of PET/CT in assessment of therapy response and restaging
- Trial name
- NCT04395651
- Testing
- PET/CT
- Volunteers
- 30 people
- Sponsor
- Assiut University
Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung
Study of the Fixation of Various Vectors in PET/CT in Patients With a With Lung Cancer Before and During of CRT or RT
Study of the modification of the fixation(binding) of Fluoro-2-deoxy-D-glucose (FDG), fluoro-misonidazole (FMISO) and 3'deoxy-3-fluoro-thymidine deoxy-3-fluoro-thymidine (FLT) measured in tomography by broadcast(emission,issue)…
- Trial name
- RTEP4 (NCT01261585)
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Centre Henri Becquerel
Atherosclerotic Cardiovascular Disease, Coronary Artery Disease
Incidental Coronary Calcification Quality Improvement Project
This is a multi-center, randomized quality improvement project. At least 200 statin-naïve patients without a history of atherosclerotic cardiovascular disease with incidental coronary artery calcium (CAC) on a prior non-gated…
- Trial name
- ICC QI (NCT04789278)
- Testing
- Notification
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Stanford University
Heart Valve Diseases
AI Assisted Screening for VHD Using Routine Chest CT Scans
This is a prospective, multicenter study designed to validate a deep learning model for screening valvular heart diseases using routine, non-contrast chest computed tomography (CT) scans.
- Trial name
- ARTEMIS (NCT07449130)
- Where
- 3 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Aortic Valve Stenosis
Preoperative Chest CT-imaging in Surgical Aortic Valve Replacement with or Without CABG
Rationale When determining the strategy for aortic valve replacement, echocardiography is still considered the golden standard (1).
- Trial name
- GUIDE-SAVR (NCT06603454)
- Testing
- Preoperative CT
- Where
- Netherlands
- Volunteers
- 380 people
- Sponsor
- Romy Hegeman
NSCLC
Dose Escalation by Boosting Radiation Dose Within the Primary Tumor Using FDG-PET-CT Scan in Stage IB, II and III NSCLC
Increasing ("boosting") the radiation dose for patients with non-small cell lung carcinoma to the individual maximal dose which can safely be given.
- Trial name
- PET Boost (NCT01024829)
- Testing
- Radiotherapy
- Where
- 7 sites in Belgium, Denmark and 3 more
- Volunteers
- 150 people
- Sponsor
- The Netherlands Cancer Institute
Hemoptysis
Utility of Bronchoscopy in Patients With Haemoptysis and Negative Chest CT Scan (ULYSSES)
Conflicting evidence exist in the literature on the utility of bronchoscopy in patients with haemoptysis and negative/non-diagnostic chest CT scan.
- Trial name
- NCT05634200
- Testing
- Bronchoscopy
- Where
- 14 sites in Italy, Spain
- Volunteers
- 150 people
- Sponsor
- University of Milan
Non-small Cell Lung Cancer, Breast Cancer
Positron Emission Tomography/Computed Tomography (PET/CT) for the Diagnosis of Recurrent Cancer: a Feasibility Study
Sometimes, cancer comes back after it has been successfully treated-a situation called recurrent cancer. When recurrent cancer is suspected, the standard approach to diagnosis is to perform a combination of imaging tests, such as…
- Conditions
- Non-small Cell Lung Cancer, Breast Cancer, Head and Neck Cancer, Ovarian Cancer
- Trial name
- PETREC (NCT00686465)
- Testing
- PET/CT scan
- Where
- 4 sites in Canada
- Volunteers
- 101 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Lung Cancer
Early Detection of Lung Cancer in a High-Risk Population Defined by PFT, Biomarkers, and CT Scanning
Lung cancer is the number one cancer killer in Kentucky and has a very high incidence within the 5th Congressional District of Kentucky (110.8 cases per 100,000 in period 1996-2000).
- Trial name
- NCT00596310
- Testing
- CT
- Where
- 4 sites in United States
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Susanne Arnold
Rib Fractures, Thoracic Injuries
Ultrasound for Diagnosing Costochondral Joint Separation
This study aims to evaluate the diagnostic effectiveness of ultrasound in detecting costochondral joint separation in patients with blunt thoracic trauma.
- Trial name
- NCT06766721
- Testing
- Ultrasound (USG)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Caner İşevi, MD
Lung Cancer
Implementing Fragmentomics Into Real World Screening IntervenTions to Evaluate Clinical Utility Among Individuals With Elevated Risk for Lung Cancer
The purpose of this study is to determine whether availability of DNA Evaluation of Fragments for Early Interception (DELFI) Lung Cancer Screening Test, FirstLook™ to practicing physicians affects overall lung cancer screening…
- Trial name
- FIRSTLUNG (NCT06145750)
- Testing
- Ability to order FirstLook™, Continuing Medical Education for Lung Cancer
- Where
- 3 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Delfi Diagnostics Inc.
Stage IIIA Non-small Cell Lung Cancer
Fludeoxyglucose F 18 PET/CT Scans in Predicting Therapy Response in Patients With Stage IIIA Non-Small Cell Lung Cancer Undergoing Chemoradiation
This clinical trial studies fludeoxyglucose F 18 (FDG) positron emission tomography (PET)/computed tomography (CT) in predicting chemoradiation therapy (CRT) failure in patients with stage IIIA non-small cell lung cancer (NSCLC).
- Trial name
- NCT01314677
- Testing
- positron emission tomography/computed tomography (PET/CT), fludeoxyglucose F 18
- Sponsor
- City of Hope Medical Center
Coronary Artery Disease, Cardiac Disease
The CAROLE (CArdiac Related Oncologic Late Effects) Study
CAROLE seeks to evaluate the relationship between chest Radiation Therapy and coronary artery disease. The purpose of CAROLE is to check the heart health of women who received breast cancer treatments in the past and protect them…
- Conditions
- Coronary Artery Disease, Cardiac Disease, Cardiac Toxicity, Radiation
- Trial name
- CAROLE (NCT03235427)
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Northwell Health
Non-small Cell Lung Cancer Metastatic, Non-small Cell Lung Cancer Stage IIIB
PET/CT Scan as a Tool to Rationalize the Treatment of of Advanced NSCLC Patients Undergoing First Chemotherapy
The purpose of this study is to test whether an early metabolic response, measured by PET/CT scan after the first cycle of chemotherapy, is able to predict which patients with advanced NSCLC have a better prognosis.
- Trial name
- PETRA (NCT02035683)
- Testing
- PET/CT
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- National Cancer Institute, Naples
Lung Cancer, Non-small-cell Lung Carcinoma
Assessment of 4D 18F-FDG PET-CT in Radiotherapy for Non Small Cell Lung Cancers
Computed tomography (CT) images, used for radiotherapy planning, are often caught out in lung target volumes delineation because of their inability to differentiate between neoplasia, inflammation and atelectasia.
- Trial name
- PULMOTEP (NCT01421953)
- Testing
- CT-simulation and 4D PET-CT
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Bordeaux