Clinical trials: Chest Pains
Acute Coronary Syndrome, Chest Pain
Efficacy Evaluation of Observation Unit Cardiac Magnetic Resonance Imaging (MRI) in Patients With Intermediate Risk Acute Chest Pain
The purpose of this study is to investigate the best way to evaluate patients with chest pain in the emergency department. It compares types of cardiac tests performed while receiving treatment in an observation unit.
- Trial name
- NCT00869245
- Testing
- OU - Cardiac MRI, OU - Conventional Care Testing
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Wake Forest University Health Sciences
Coronary Artery Disease, Chest Pain
Effects of Heart Imaging Radiation on DNA Double-Stranded Breaks in Blood Lymphocytes and Hair Follicle Cells
Purpose 1. To investigate the effects of cardiac imaging radiation on the induction of DNA double-strand breaks by enumerating gamma-H2AX foci in blood lymphocytes and plucked hair follicle cells. 2.
- Trial name
- NCT02617888
- Testing
- CCTA ~ BREAST SHIELDS
- Volunteers
- 228 people
- Sponsor
- Walter Reed National Military Medical Center
Coronary Heart Disease, Angina Pectoris
Aspirin Non-responsiveness and Clopidogrel Endpoint Trial.
In the ASCET study, 1000 patients with documented coronary heart disease will be randomized to either continued treatment with aspirin 160 mg/d or change to clopidogrel 75mg/d.
- Conditions
- Coronary Heart Disease, Angina Pectoris, Atherosclerosis
- Trial name
- ASCET (NCT00222261)
- Testing
- aspirin, clopidogrel
- Where
- Norway
- Volunteers
- 1,001 people
- Sponsor
- Ullevaal University Hospital
Lung Cancer
Study of Prevalence of Ipsilateral Shoulder Pain in Patients After Thoracic Surgeries
Thoracic surgeries are associated with significant operative trauma1. While thoracic epidural analgesia may help control the incisional component of the pain, an excruciating postthoracotomy.
- Trial name
- NCT03249766
- Testing
- Observational
- Where
- India
- Volunteers
- 370 people
- Sponsor
- Tata Memorial Hospital
Chest Pain
Magnetocardiography as a Tool for Patients Presenting With Chest Pain - Pilot Study
The purpose of this pilot research study is to identify the characteristics of magnetocardiograms that correlate with a non ischemic chest pain status and a myocardial infarction patient status.
- Trial name
- NCT02359773
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Quantum Imaging Limited
Lung Neoplasms, Thoracic Surgery
Comparison of Post-operative Pain and Quality of Life Between Subxiphoid and Intercostal VATS for Lung Cancer
One-thirds of patients underwent video-assisted thorascopic surgery (VATS) still have severe pain.Uniportal lobectomy or segmentectomies emerged as a promising and exciting approach for minimally invasive thoracic surgery.
- Conditions
- Lung Neoplasms, Thoracic Surgery, Carcinoma, Non-Small-Cell Lung, Lung Diseases
- Trial name
- NCT03331588
- Testing
- Subxiphoid uniportal VATS, Intercostal uniportal VATS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Thoracic Outlet Syndrome
Treatment of Thoracic Outlet Syndrome (TOS) With Botox
The purpose of this study is: 1. To assess the effect of BOTOX injection to the scalene muscles on the severity of pain from TOS. 2. To assess the effect of BOTOX injection on numbness and tingling and quality of life.
- Trial name
- NCT00444886
- Testing
- Botulinum Toxin Type A injection (BOTOX)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Pain, Postoperative
Thoracic Paravertebral Blockade in Video Assisted Thoracoscopic Surgery (VATS)
Video-assisted thoracoscopic surgeries (VATS) include severe postoperative acute pain which is also a predictor of chronic pain.
- Trial name
- VATS (NCT02302586)
- Testing
- Thoracic paravertebral block (TPVB), Patient Controlled Analgesia (IV PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Chronic Pain, Erector Spinea Plane Block
Tramadol Hydrochnoride as Adjuvant to Local Anesthetic in Ultrasound Guided Erector Spinea Plane Block in Management of Chronic Chest Wall Cancer Pain
Chest wall pain is a severe and distressing symptom. The erector spinae plane block (ESPB) is an interfascial plane block where local anesthetic is injected between the erector spine muscle and the transverse process.
- Trial name
- NCT04639154
- Testing
- Erector spinea plane block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Neck Pain, Low Back Pain
Evaluation of the Effects of a Rehabilitation Program in Individuals with Spine Pain
SpineZone is an innovative physical therapy program with its focus on treatment of cervical, thoracic, and lumbar conditions through the use of a multi-disciplinary, technology enabled platform.
- Conditions
- Neck Pain, Low Back Pain, Scoliosis, Thoracic Injuries
- Trial name
- NCT04081896
- Testing
- Exercise
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- SpineZone Medical Fitness, Inc
Postoperative Pain
Analgesic Efficacy of Transversus Thoracic Muscle Plane Block on Post-sternotomy Pain
Patients were randomly allocated to either Tansversus group (T group) and general anesthesia (N group).Patient demographic data, preoperative medical status, left ventricular function, and operative data (total ischemic time…
- Trial name
- NCT04872192
- Testing
- transversus thoracic muscle plane block, general anaesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Stable Angina, Coronary Disease
Research on Nicorandil Treatment of Patients Diagnosed as CHD (Coronary Heart Disease) With Stable Angina
This study of 402 cases of stable angina subjects who were diagnosed as Coronary Heart Disease (CHD) is a randomized, blank controlled, multi-center clinical study.
- Trial name
- SIGMART (NCT01396395)
- Testing
- Nicorandil, Standard Treatment
- Where
- China
- Volunteers
- 402 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Thoracic Surgery, Uniportal Video Assisted Thoracic Surgery (U-VATS)
Erector Spinae Plane Block in Uniportal VATS
The main aim of this study is to compare the effectiveness of three alternative techniques (continuous Erectus Spinae Plane Block : c-ESPB; continuous Serratus Anterior Plane Block : c-SAPB; and Intercostal Nerve Block: ICNB) in…
- Conditions
- Thoracic Surgery, Uniportal Video Assisted Thoracic Surgery (U-VATS), Lung Resections, Post-Operative Pain, Chronic
- Trial name
- ESPB-UVATS (NCT04892901)
- Testing
- c-ESPB, c-SAPB, ICNB
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Angina Pectoris, Atherosclerosis
Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease 2
In a cohort of symptomatic patients referred to coronary computed tomography angiography (CCTA), the investigators aim: 1. To investigate and compare the diagnostic precision of Rubidium Positron Emission Tomography (Rb PET) and…
- Conditions
- Angina Pectoris, Atherosclerosis, Coronary Artery Disease, Myocardial Ischemia
- Trial name
- Dan-NICAD 2 (NCT03481712)
- Testing
- Diagnostic tests
- Where
- 5 sites in Denmark
- Volunteers
- 1,732 people
- Sponsor
- University of Aarhus
Back Pain, Spine Stiffness
The Effects of Thoracic Manipulation on Peripheral Muscle Oxygenation
Office workers spend 70-85% of their time sitting, which leads to postural disorders and musculoskeletal system diseases. Back pain is the most common health problem among office workers who need to sit.
- Conditions
- Back Pain, Spine Stiffness, Sedentary Behavior, Disability Physical
- Trial name
- NCT06704373
- Testing
- thoracal manipulation, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Bahçeşehir University
Astrocytoma, Brain Cancer
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S
This is a multi-center, open-label, dose escalation study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and maximum tolerated dose (MTD) of QBS10072S in patients with advanced or metastatic cancers…
- Conditions
- Astrocytoma, Brain Cancer, Brain Metastases, Bladder Cancer
- Trial name
- NCT04430842
- Testing
- QBS10072S
- Where
- 2 sites in Australia
- Volunteers
- 15 people
- Sponsor
- Quadriga Biosciences, Inc.
Wounds and Injuries, Rib Fractures
Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients
This study will evaluate the effectiveness of ketamine infusions in the management of acute pain resulting from broken ribs suffered following a blunt trauma.
- Trial name
- NCT02432456
- Testing
- Ketamine, Intercostal Nerve Block, Acetaminophen
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Medical College of Wisconsin
Arterial Hypertension, Diabetes Mellitus
Azilsartan Medoxomil in Hypertensive pAtients With Stable Ischemic Heart Disease and DiabEtes MEllitus.
One-center, observational, non-interventional, prospective study of the efficacy of azilsartan medoxomil in patients with arterial hypertension associated with stable ischemic heart disease and type 2 diabetes mellitus.
- Conditions
- Arterial Hypertension, Diabetes Mellitus, Stable Chronic Angina
- Trial name
- AcADEME (NCT03539627)
- Testing
- Azilsartan Medoxomil 40 MG Oral Tablet [Edarbi]
- Where
- Russia
- Volunteers
- 184 people
- Sponsor
- Research Institute for Complex Problems of Cardiovascular Diseases, Russia
Angina
Effect of Oxygen During Percutaneous Coronary Intervention for Pain Relief
Nasal oxygen is widely used as pain relief against ischemic pain during Percutaneous Coronary Intervention (PCI). However, to our knowledge no randomised clinical trials have tested this.
- Trial name
- OXYPAIN (NCT01413841)
- Testing
- Nasal oxygen, Regular nasal air
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
Stable Angina, Unstable Angina
Atorvastatin for Reduction of Myocardial Damage During Angiography and Its Mechanism Associated With IMR
The purpose of this study is to determine whether preoperative loading dose atorvastatin can prevent perioperative myocardial infarction during angiography and main adverse cardiac events 1 month after operation in stable angina…
- Conditions
- Stable Angina, Unstable Angina, Acute Non-ST-segment Elevation Myocardial Infarction
- Trial name
- ARMYDA-IMR (NCT01761656)
- Testing
- loading dose atorvastatin, conventional dose atorvastatin
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Central South University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.