Clinical trials: Child Development
Preterm Birth, Prematurity
Parent-child Interactions, Child Developmental Health, and Health System Costs at 6 Months Corrected Age
The aim of this novel health services research proposal is to assess the longer-term outcomes, to 6 months corrected age, of an adapted Family Integrated Care (FICare) model of care for moderate and late preterm infants admitted…
- Conditions
- Preterm Birth, Prematurity, Infant,Premature, Infant Development
- Trial name
- NCT03357458
- Testing
- Family Integrated Care
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Calgary
Autism Spectrum Disorder
Acceptability and Efficacy of a Culturally Adapted, Low-Frequency Parent-Mediated Early Start Denver Model (ESDM) Versus Standard Care in Young Children With Autism
Early intervention is effective in improving developmental outcomes of children on the autism spectrum. However, cultural and contextual factors may influence parental acceptability of treatment models, highlighting a need for…
- Trial name
- NCT07840586
- Testing
- Early Start Denver Model
- Where
- Singapore
- Volunteers
- 58 people
- Sponsor
- National University Hospital, Singapore
Autism Spectrum Disorder, Intellectual Disability
Transcranial Magnetic Stimulation Studies in Autism Spectrum Disorders
Autism Spectrum Disorder (ASD) is the most prevalent of the developmental disorders and their incidence is rising. However, the variability in the behavioral symptoms is large.
- Trial name
- NCT02591446
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Early Childhood Professional Development
Study of Coaching Practices in Early Care and Education Settings
Mathematica Policy Research, funded by the Administration for Children and Families (ACF) in the U.S. Department of Health and Human Services (HHS) will collect descriptive information for the Study of Coaching Practices in Early…
- Trial name
- SCOPE (NCT03743337)
- Where
- United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Autism Spectrum Disorder
Electrical Brain Stimulation and Pharmacological Treatments in Autism Spectrum Disorder
This project aims to comparing the effectiveness of transcranial direct current stimulation with common pharmacological treatments on behavioral problems and cognitive deficits of children with autism spectrum disorder
- Trial name
- NCT05491720
- Testing
- RisperiDONE 1 MG/ML, transcranial direct current stimulation
- Where
- Iran
- Volunteers
- 45 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Autism, Major Depressive Disorder (MDD)
Investigating the Brain's Physiological Responses in Depression and Autism, Using Transcranial Magnetic Stimulation and Electroencephalography
The goal of this observational study is to investigate the brain physiological responses in depression and autism. The main questions aim to answer are: 1.
- Trial name
- NCT06821646
- Testing
- Positron Emission Tomography (PET), transcranial magnetic stimulation and electroencephalography(TMS-EEG)
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
CPI Training for Parents of Children With ASD
The purpose of this 24-week study is to determine whether the "Parent-based Crisis Prevention Institute (CPI) physical management training program" (i.e., P-CPI) is effective in increasing self-efficacy in parents of children…
- Trial name
- NCT03537261
- Testing
- Parent-based Crisis Prevention Institute (CPI) physical management training program (P-CPI)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Emotion Regulation, Autism Spectrum Disorder
Equine-assisted Therapy for Therapy-resistant Adolescents With Autism Spectrum Disorders, a Replicated AB-design
The purpose of this study is to assess the (cost)effectivity of Equine assisted Therapy in adolescents with Autism Spectrum disorders.
- Conditions
- Emotion Regulation, Autism Spectrum Disorder, Adolescent - Emotional Problem
- Trial name
- NCT05200351
- Testing
- Equine assisted Therapy (EAT)
- Where
- 3 sites in Netherlands
- Volunteers
- 35 people
- Sponsor
- Karakter Kinder- en Jeugdpsychiatrie
Autism Spectrum Disorder
Medial Prefrontal Cortex Brain Magnetic Stimulation in Autism
Despite decades of research, no definitive, effective biological treatments exist for core symptoms of Autism Spectrum Disorder (ASD).
- Trial name
- NCT07770451
- Testing
- TMS
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorders
Intranasal Oxytocin and Learning in Autism
: The objective of this study is to determine the tolerability and therapeutic potential of oxytocin in children and adolescents with Autism Spectrum Disorders (ASD) when paired with a computer game intervention that is designed…
- Trial name
- NCT02090829
- Testing
- Syntocinon (synthetic oxytocin)
- Where
- United States
- Sponsor
- University of Minnesota
Children With Cerebral Palsy
Analysis of Trunk and Center of Mass Control Development During Gait in Children With Cerebral Palsy (VERTEBRAL)
During the acquisition of posturokinetic abilities such as walking, postural control of the trunk is of paramount importance. Indeed, its development is strongly linked to the overall motor function of children.
- Trial name
- VERTEBRAL (NCT06320288)
- Where
- France
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Autistic Disorder
Sapropterin as a Treatment for Autistic Disorder
This study is intended to provide a definitive test of the hypothesis that elevating sapropterin (tetrahydrobiopterin, a cofactor for several key brain enzymes)concentrations in the CNS will result in measurable improvements in…
- Trial name
- NCT00850070
- Testing
- sapropterin
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- The Children's Health Council
Child Development
PROmoting Early Childhood Outside (PRO-ECO)
Licensed early learning and childcare centres (ELCCs) can provide children with rich opportunities for outdoor play that they may not otherwise experience in their home or community.
- Trial name
- PRO-ECO (NCT05073380)
- Testing
- Intervention Group - PRO-ECO Intervention, Wait List Group - Normal Daily Practice
- Where
- Canada
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Autism Spectrum Disorder, Autism
Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined.
Autism spectrum disorder (ASD) is a neurodevelopmental condition with core deficits in social communication and behavior, often accompanied by gastrointestinal (GI) and metabolic dysfunction.
- Conditions
- Autism Spectrum Disorder, Autism, Autism Spectral Disorder
- Trial name
- GARM-Autism (NCT07546942)
- Testing
- Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells, Fecal Biomicrome Transplantation (FMT), Ketogenic RESET Diet Protocol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Black Tie Medical, Inc.
Autism Spectrum Disorders, Non-verbal Learning Disorder
Comparison of ABLLS-R and Portage Guide in the Development of Receptive Language Skills Autism Spectrum Disorder.
Language is the system someone uses to communicate with another person. This covers the origins and construction of words, their definitions, and the use of language in various contexts.
- Trial name
- NCT06292520
- Testing
- Portage Guide Protocol, ABLLS-R protocol
- Where
- Pakistan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Motor Activity, Child Development
Effects of a Physical Education Programme in Preschool Children
Unlike other European countries, Italian kindergartens do not include the physical education teacher in the school organic personnel.
- Trial name
- NCT03454061
- Testing
- physical activity
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Autism Spectrum Disorder
Pediatric Early Autism Recognition System: PEARS
The goal of the study is to assess a new autism evaluation model that would include the addition of a Level-2 autism screener, the Rapid Interactive Screening Test for Autism in Toddlers (RITA-T), to the developmental screening…
- Trial name
- PEARS (NCT05153551)
- Testing
- Play-based assessment (RITA-T)
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Gross Motor Development Delay
Education Program for Caregivers of Children With Gross Motor Delays
The main objective of this project is to determine whether an educational intervention delivered via social media can improve parent understanding of child development and progression in child's developmental goals.
- Trial name
- NCT05542251
- Testing
- Parent Educational Program
- Where
- 3 sites in United States
- Volunteers
- 92 people
- Sponsor
- Emory University
Child Development, Child Development Disorder
The Indonesian Version of Ages and Stages Questionnaire III Accuracy Compared to Bayley Scales of Infant Development III
This study aimed to evaluate the concurrent validity information of the 24-, 30-, and 36-month Indonesian ASQ-3 with the Bayley Scales of Infant and Toddler Development 3rd Edition (BSID-III) in Indonesian children.
- Conditions
- Child Development, Child Development Disorder, Development Delay, Developmental Delay
- Trial name
- NCT05408351
- Where
- Indonesia
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Depression, Autism
Behavioral Activation for Treatment of Depression in Adolescents With Autism
In this study, the investigators will examine the feasibility, acceptability, and preliminary efficacy of a novel, behavior-based approach for treatment of depression symptoms in adolescents with autism spectrum disorder or ASD…
- Trial name
- BA-A (NCT05018169)
- Testing
- BA-A
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Virginia