Clinical trials: Childhood Autism
Autism Spectrum Disorders
Magnetic Resonance Spectroscopic and Diffusion Tensor Imaging of Adolescents with Autism Spectrum Disorders
The primary objective of this study is to conduct magnetic resonance spectroscopic (MRS) and imaging (MRI) scans to assess the structural and neurochemical profile of the brain in 20 children and adolescents, 6-17 years old with…
- Trial name
- NCT01361503
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Cognitive Remediation for Autistic Adolescents
Autistic youth have extremely high levels of co-occurring mental health difficulties, including rates of depression and anxiety which are between two and four times more common compered to non-autistic people.
- Trial name
- NCT06989151
- Testing
- Cognitive Remediation Therapy
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- South London and Maudsley NHS Foundation Trust
ASD
Internal Versus External Attentional Focus in Gross- and Fine-Motor Learning Among Children With Autism Requiring Ongoing Everyday Support
This study examined how different attentional focus instructions affect motor learning in children with autism spectrum disorder (ASD).
- Trial name
- NCT07851272
- Testing
- External Focus of Attention Instructions, Internal Focus of Attention Instructions
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- University of Haifa
Autism Spectrum Disorder, Speech
Thinking in Speech for Children With Autism
This study examines a cognitive therapy for autistic children, Thinking in Speech. Thinking in Speech helps children with autism independently cope with everyday events that cause stress, by developing their ability to use "inner…
- Trial name
- NCT05256095
- Testing
- Thinking in Speech
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder
Leucovorin for the Treatment of Language Impairment in Children With Autism Spectrum Disorder
The purpose of this study is to determine the effectiveness of folinic acid in the treatment of language problems in children with autism spectrum disorder. Folinic acid, also known as leucovorin, is approved by the U.S.
- Trial name
- NCT02839915
- Testing
- Folinic Acid
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Southwest Autism Research & Resource Center
16P11.2 Deletion Syndrome, 16p11.2 Duplications
Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight
Simons Searchlight is an observational, online, international research program for families with rare genetic variants that cause neurodevelopmental disorders and may be associated with autism.
- Conditions
- 16P11.2 Deletion Syndrome, 16p11.2 Duplications, 1Q21.1 Deletion, 1Q21.1 Microduplication Syndrome (Disorder)
- Trial name
- NCT01238250
- Where
- 2 sites in United States
- Volunteers
- 100,000 people
- Sponsor
- Simons Searchlight
Autism Spectrum Disorder, Suspected Autism
Caregiver Training to Support Children With Social Communication Challenges
"More Than Words® - The Hanen Program® for Parents of Autistic Children or Children Who May Benefit from Social Communication Support" is a family-focused intervention program delivered by a speech-language pathologist (SLP).
- Conditions
- Autism Spectrum Disorder, Suspected Autism, Social Communication Challenges
- Trial name
- NCT06909279
- Testing
- The Hanen Centre's More Than Words® program
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Western University, Canada
Autism Spectrum Disorder
Interactive Mirroring Games wIth sOcial Robot (IOGIOCO) and Robotic System Adapted Into a Clinical Scale (RISCALE)
Background: The importance of early intervention in Autism Spectrum Disorders (ASD) has been widely demonstrated, and developmental trajectories in ASD highlight the importance of nonverbal communication, such as intransitive…
- Trial name
- RISCALE (NCT06855446)
- Testing
- Intervention with social robot NAO, Treatment as usual
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Language Delay, Language; Developmental Disorder, Expressive
Intranasal Inhalations of M2 Macrophage Soluble Factors in Children With Developmental Speech Disorders
The investigators have designed an innovative proof-of-concept trial designed to provide data as to whether the speech difficulties in children with developmental dysphasia (DD) are improved with intranasal inhalations of…
- Conditions
- Language Delay, Language; Developmental Disorder, Expressive, Language; Developmental Disorder, Receptive, Autism Spectrum Disorder
- Trial name
- NCT04689282
- Testing
- Bioactive Factors, Produced by M2 Type Macrophages (M2-BFs).
- Where
- Russia
- Volunteers
- 14 people
- Sponsor
- Russian Academy of Medical Sciences
Autism Spectrum Disorder
A Placebo-controlled Trial of Folinic Acid in Children With ASD
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by difficulties in social communication and the presence of restricted or repetitive behaviors.
- Trial name
- AFAT (NCT07642661)
- Testing
- Folinic Acid
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Prof. Adi Aran
Autism Spectrum Disorder
STRW-T Intervention for Autistic Adolescents in 11th and 12th Grade
The current study seeks to compare outcomes of a telehealth intervention targeting daily living skills (Surviving and Thriving in the Real World - Telehealth, or STRW-T) intervention to a control group telehealth intervention…
- Trial name
- STRW-T (NCT06552286)
- Testing
- STRW-T, PEERS-T
- Where
- 2 sites in United States
- Volunteers
- 192 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder, Gastrointestinal Disorder
Microbiota Transfer Therapy for Adults With Autism Spectrum Disorder (ASD) Who Have Gastrointestinal Disorders
This is a clinical trial of Microbiota Transplant Therapy (MTT) for adults with autism spectrum disorders (ASD) who have gastrointestinal problems.
- Trial name
- MTT-ASD (NCT03408886)
- Testing
- Vancomycin, MoviPrep, Full Spectrum Microbiota
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Arizona State University
Autism Spectrum Disorder
Translating Neuroprediction Into Precision Medicine Via Brain Priming
The present study examines the impact of oxytocin (OXT) and Pivotal Response Treatment (PRT) on the development of language, social, and play skills in young children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT03370510
- Testing
- Oxytocin, Pivotal Response Treatment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Autism Spectrum Disorder, Healthy
Investigating the Clinical Utility of the Oxford Virtual Autism Assessment Tool (OVAAT)
The goal of the study is to evaluate a new Autism Spectrum Disorder (ASD) diagnostic tool (Oxford Virtual Autism Assessment Tool (OVAAT)) to see whether it can: Be able to identify autistic traits Be able to distinguish between…
- Conditions
- Autism Spectrum Disorder, Healthy, Neurotypical
- Trial name
- NCT06582290
- Testing
- Oxford Virtual Autism Assessment Tool (OVAAT)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oxford Health NHS Foundation Trust
Autism Spectrum Disorder, Self-Injurious Behavior
Deep Brain Stimulation in Children With Autism
The purpose of this study is to evaluate the safety and possible effectiveness of deep brain stimulation (DBS) of the nucleus accumbens in children with autism spectrum disorder and treatment-refractory, repetitive self-injurious…
- Trial name
- NCT03982888
- Testing
- Deep Brain Stimulation, DBS
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- The Hospital for Sick Children
ASD
Evaluate the Efficacy and Safety of DHA in the Adjuvant Treatment of Children With ASD.
In the etiopathogenesis of autistic spectrum disorder (ASD) several hypotheses have been described that include inflammation, metabolic alterations, activation of oxidative stress, changes in the intestinal microbiota and in the…
- Trial name
- NCT03620097
- Testing
- EuPoly-3 DHA Infant
- Volunteers
- 60 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Child Autism
Hyperbaric Oxygen Treatment in Autism Spectrum Disorders
Hyperbaric oxygen therapy (HBOT) is part of a multidisciplinary therapeutic management of infant autism including psychotherapy, drug treatment and other therapeutics (speech therapy, occupational therapy restrictive diet ...).
- Trial name
- NCT04472780
- Testing
- Hyperbaric oxygen Therapy HBOT
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- General Administration of Military Health, Tunisia
Autism Spectrum Disorder
Study of the Visual Perception During Emotional States on Subjects With an Intrusive Disorder of the Development
The Pervasive Developmental Disorders (PDD) are severe neurodevelopmental disorders, affecting nearly 1% of the general population.
- Trial name
- VisioTED (NCT02827279)
- Testing
- emotional induction
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder
A Multi-site Comparison of Social Visual Engagement to Clinical Diagnosis for Autism Spectrum Disorder
This is an outpatient, multicenter, prospective, pivotal, double-blind, within-subject comparison trial of the Marcus Autism Center Investigational Device (MAC-ID) diagnostic procedure relative to the gold-standard (reference…
- Trial name
- NCT03469986
- Testing
- Marcus Autism Center Investigational Device
- Where
- 6 sites in United States
- Volunteers
- 505 people
- Sponsor
- EarliTec Diagnostics, Inc
Autism Spectrum Disorder
Assessment of the Usability/acceptability of the Little Journey App by Parents/guardians/legal Representatives and Children Aged Between 3-12 Years Old Who Have a Diagnosis of Autism Spectrum Disorder (ASD).
Assessment of the usability/ acceptability of the Little Journey app with children aged between 3-12 years old with a diagnosis of autism spectrum disorder (ASD) and experience of attending hospital for a procedure, and their…
- Trial name
- NCT06598358
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Little Journey
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