Clinical trials: Childhood Autism
Autism Spectrum Disorder With Language Delay
pBFS Guided Neuromodulation Over DMPFC for ASD Treatment: Pilot Study
This study will evaluate the feasibility and preliminary efficacy of pBFS-guided TMS treatment at DMPFC in autism spectrum disorder comorbid with language delay.
- Trial name
- NCT07515261
- Testing
- active iTBS
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Changping Laboratory
Autism Spectrum Disorder
A 12-weeks Study to Evaluate Sulforaphane in Treatment of Autism Spectrum Disorder
In this proposed study, the investigators will evaluate the the efficacy, safety and related mechanism of sulforaphane in treatment of autism spectrum disorder (ASD).
- Trial name
- NCT02879110
- Testing
- Sulforaphane
- Where
- 2 sites in China
- Volunteers
- 110 people
- Sponsor
- Central South University
Prosocial Behavior, Emotional Regulation
Comparison Between a Live Canine or Toy Dog on Prosocial Behavior and Emotional Regulation in Autistic Children
This study investigated the human-animal interaction (HAI) and bond (HAB) between a canine trained in therapy techniques or a canine plush toy and youth with autism spectrum disorder (ASD) during animal-assisted therapy (AAT)…
- Conditions
- Prosocial Behavior, Emotional Regulation, Human Animal Bonding, Human Animal Interaction
- Trial name
- NCT06915415
- Testing
- Animal-assisted therapy, Behavioral therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Arkansas, Fayetteville
Autism Spectrum Disorder, Irritability
Behavior Therapy for Irritability in Autism
This is a clinical trial of a novel intervention, Behavioral Therapy for Irritability and Aggression (BTIA), for adolescents on the autism spectrum.
- Conditions
- Autism Spectrum Disorder, Irritability, Disruptive Behavior, Anger
- Trial name
- BTIA (NCT04654260)
- Testing
- Behavioral Therapy for Irritability in Autism, Psychoeducation and Supportive Therapy (PST)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Yale University
Autism, Autism Disorder
Role of the Gut Vascular Barrier and Microbiota in Autism Spectrum Disorders
Recent research links gut microbiota alterations to Autism Spectrum Disorders (ASD), a neurobiological condition with multifactorial bases.
- Conditions
- Autism, Autism Disorder, Autism Spectrum Disorder (ASD)
- Trial name
- DSA/GVB (NCT07450443)
- Testing
- PostbiotiX Comfort®, Control
- Where
- 2 sites in Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Autism Spectrum Disorder
Hybrid Computerized EF Training Using Virtual Human Stimuli for Autism
The goal of this pilot clinical trial is to learn the preliminary feasibility and efficacy of a home-based hybrid computerized executive function (EF) training program using social stimuli for autistic individuals.
- Trial name
- NCT07308210
- Testing
- Hybrid computerized executive function training
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- Education University of Hong Kong
Neuromuscular Diseases, Cerebral Palsy
Hippotherapy to Improve the Balance of Children With Movement Disorders
The purpose of this study is to determine if adding hippotherapy treatment will improve balance for children ages 5-17 who have disabilities such as cerebral palsy and down syndrome.
- Conditions
- Neuromuscular Diseases, Cerebral Palsy, Down Syndrome, Autism
- Trial name
- HPOT (NCT01313325)
- Testing
- Hippotherapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Central Michigan University
Autism Spectrum Disorder
CASCADE: CAnnabidiol Study in Children With Autism Spectrum DisordEr
This is a randomized, placebo-controlled study but all study participants will receive the active study medication at some point during the study for at least 12 weeks, and some children with receive CBD for the entire study.
- Trial name
- CASCADE (NCT04520685)
- Testing
- Oral cannabidiol 100mg/mL
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Colorado, Denver
Irritability Associated With Autism Spectrum Disorder, Autism Spectrum Disorder
A Study of JZP541 in Adults With Irritability Associated With Autism Spectrum Disorder
Behavior dysregulation is commonly associated with people with autism spectrum disorder (ASD). Irritability is a major safety concern in adults with ASD.
- Conditions
- Irritability Associated With Autism Spectrum Disorder, Autism Spectrum Disorder, ASD
- Trial name
- NCT05733390
- Testing
- JZP541
- Where
- United States
- Sponsor
- Jazz Pharmaceuticals
Autism Spectrum Disorder
Mindfulness for Parents of Children With Autism Spectrum Disorder Autism Spectrum Disorder
The current study examines the efficacy of Mindfulness-Based Stress Reduction (MBSR) to reduce parenting stress, lessen parental reactivity and negativity, and decrease child externalizing behaviors among families of children…
- Trial name
- ASD (NCT03459625)
- Testing
- Mindfulness-Based Stress Reduction (MSBR), Psychoeducational Support Group (PE)
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Loma Linda University
Children With Autism Spectrum Disorder
The Effects of Physical Activity Program on Psychomotor and Psycho-Social Characteristics of Autistic Children
The aim of this study was to examine the effect of Physical Activity Program (PAP) on psychomotor and psychosocial characteristics of autistic children.
- Trial name
- NCT07273240
- Testing
- Physical Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Autism Spectrum Disorder
Affective Prosody Recognition and Auditory Intervention for Children With Autism Spectrum Disorders (ASD)
The proposed study aims to examine the abilities of children with ASD to recognize emotional tones of voice - also known as affective prosody - as compared to typically developing (TD) children.
- Trial name
- NCT04427150
- Testing
- Auditory Training, Non-auditory training
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Autistic Spectrum Disorder
Nutritional Status and ASD Severity of Autistic Spectrum Disorder Children in Addis Ababa, Ethiopia; Case Control Study
The study conducts a case control analysis of the nutritional status and intake of autistic spectrum disorder diagnosed children as compared to typically developing children in Addis Ababa, Ethiopia.
- Trial name
- ASD (NCT05515913)
- Testing
- Nutritional status, Eating behavior, Urine iodine concentration
- Where
- Ethiopia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Addis Ababa University
Autism Spectrum Disorder, Autism
Examining the Effects of a Job Entry Intervention
The current study will examine the efficacy of a virtual reality (VR) intervention as well as a newly developed Kessler Foundation STRength IDentification and Expression tool (VR-STRIDE) with adolescents diagnosed with autism…
- Conditions
- Autism Spectrum Disorder, Autism, ASD
- Trial name
- IMPRESSIVE (NCT04771338)
- Testing
- VR-JIT/KF-STRIDE
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Autism Spectrum Disorder
OCCUPATIONAL THERAPY INTERVENTIONS ON COGNITIVE PERFORMANCE IN CHILDREN WITH AUTISM SPECTRUM DISORDER
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and interaction, as well as restricted and repetitive patterns of behavior.
- Trial name
- COGNITIVE PERF (NCT07818538)
- Testing
- Virtual Reality-Supported Cognitive-Focused Occupational Therapy, Structured Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Biruni University
Autism Spectrum Disorder
Examining the Efficacy of the Anxiety Meter for Recognition and Management of Anxiety Signs in Autism Spectrum Disorder
The purpose of the study is to determine if a new device, called the Anxiety Meter, improves recognition and management of psychological arousal associated with anxiety in children with ASD.
- Trial name
- NCT02160691
- Testing
- Anxiety Meter
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
Evaluation of Some Inflammatory Markers in Autism Spectrum Disorders
Evaluate some Inflammatory markers [IL-6, IL-8, TNF_alpha] in children with autism spectrum disorder
- Trial name
- NCT05803005
- Testing
- inflammatory marker in autism spectrum disorder
- Volunteers
- 100 people
- Sponsor
- Assiut University
Autism Spectrum Disorder, Autism
A Center Based Study of Pivotal Response Treatment for Preschoolers With Autism
The purpose of this study is to examine the effectiveness of pivotal response training (PRT) in an intensive center-based environment to treat social communication deficits in children with autism spectrum disorder (ASD).
- Trial name
- PRT-C (NCT03778827)
- Testing
- Intensive Center-Based Pivotal Response Treatment (PRT-C)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
Effect of Aquatic Training on Motor Function in Children With Autism Spectrum Disorder
Clinically, infants with Autism Spectrum Disorder often display gross motor delays in supine, prone, and sitting skills in their first year of life .
- Trial name
- NCT05123066
- Testing
- Aquatic Exercises, Land Exercises
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Autism
Therapeutic Intervention Effects of rTMS on Children With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a common and complex neurodevelopmental disorder, which is characterized by impairments of social communication, social reciprocity, as well as restricted and repetitive behaviors (RRB).
- Trial name
- NCT05140356
- Testing
- Applied high amplitude repeated transcranial magnetic stimulation, Applied low amplitude repeated transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- University of Electronic Science and Technology of China
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