Clinical trials: Children Development
Neurodevelopmental Disorders, Autism Spectrum Disorder
Description of the Impact of the Modelo Sentido's® on Adaptive Behaviors in Children With Autism
Knowing the impact of the Modelo Sentido´s® (MS) on the gain of adaptive behaviors in children on the autism spectrum (AS) and other associated neurodevelopmental challenges (ANDC), is essential to improve the quality of life of…
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Adaptive Behaviors
- Trial name
- Sentido´s (NCT06477666)
- Testing
- Sentido's® Model
- Where
- Argentina
- Volunteers
- 24 people
- Sponsor
- Sentido's CAIP & CICI Organización Terapéutica
Chronic Pain, Exposure
Agile Development of a Digital Exposure Treatment for Youth With Chronic Musculoskeletal Pain
This project proposes to systematically develop and evaluate the feasibility and preliminary effectiveness of a digitally delivered, graded exposure treatment for youth with chronic musculoskeletal pain, utilizing a sequential…
- Conditions
- Chronic Pain, Exposure, Adolescent Behavior, Child Behavior
- Trial name
- NCT05079984
- Testing
- Graded exposure treatment (GET)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Stanford University
Social Anxiety in Autistic Adults
Phase 2 Pilot Safety Study of MDMA-assisted Therapy for Social Anxiety in Autistic Adults
The goal of this clinical trial is to learn if MDMA-assisted therapy is safe and effective at reducing social anxiety in adults with autism.
- Trial name
- NCT02008396
- Testing
- Midomafetamine HCl, Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Resilient Pharmaceuticals
Healthy, Healthy Lifestyle
Positive Youth Development in the Metaverse
This pilot study aims to leverage VR's capacity to easily replicate content and allow for multiple users to share the same space and engage in activities as if they're meeting in person.
- Conditions
- Healthy, Healthy Lifestyle, Childhood ALL, Behavior, Child
- Trial name
- NCT05858593
- Testing
- Virtual reality curriculum, No Virtual reality curriculum
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Autism Spectrum Disorder
Daily Living Skills Intervention for Adolescents With Autism Spectrum Disorder
The main objective of the current proposal is to conduct a pilot RCT (i.e., treatment group and social skills control group) to examine how participation in Surviving and Thriving in the Real World (STRW) Intervention affects…
- Trial name
- NCT03984487
- Testing
- Surviving and Thriving in the Real World, Program for the Education and Enrichment of Relational Skills
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT05325333
- Testing
- Retrieval-based word learning: Expanding retrieval practice schedule, Retrieval-based word learning: Standard retrieval practice schedule
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Autism, Autism Spectrum Disorder
Intranasal Vasopressin Treatment in Children With Autism
The purpose of this clinical trial is to investigate the effectiveness of vasopressin nasal spray for treating symptoms associated with autism.
- Conditions
- Autism, Autism Spectrum Disorder, ASD
- Trial name
- NCT03204786
- Testing
- Vasopressin (USP) Injectable Solution [Vasostrict]
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Stanford University
Osteogenesis Imperfecta
Study to Evaluate Romosozumab in Children and Adolescents With Osteogenesis Imperfecta
The primary objective of this study is to evaluate the pharmacokinetics (PK) profile following multiple subcutaneous (SC) doses of romosozumab in children and adolescents with Osteogenesis Imperfecta (OI).
- Trial name
- NCT04545554
- Testing
- Romosozumab, Calcium, Vitamin D
- Where
- 15 sites in United States, Austria and 6 more
- Volunteers
- 25 people
- Sponsor
- Amgen
Autistic Disorder
Sapropterin as a Treatment for Autistic Disorder
This study is intended to provide a definitive test of the hypothesis that elevating sapropterin (tetrahydrobiopterin, a cofactor for several key brain enzymes)concentrations in the CNS will result in measurable improvements in…
- Trial name
- NCT00850070
- Testing
- sapropterin
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- The Children's Health Council
Autistic Disorder
Open-Label Extension Study of Kuvan for Autism
This is an open-label extension study available only to subjects who completed an earlier double-blind, placebo-controlled study of sapropterin in children with autism.
- Trial name
- NCT00943579
- Testing
- Kuvan®
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- The Children's Health Council
Autism Spectrum Disorder
Screening for Autism Spectrum Disorders Using Auditory Brainstem Responses
The purpose of this study is to develop an Auditory Brainstem Response (ABR) based neurological screening method to detect increased risk for Autism Spectrum Disorders (ASD) and other neurological conditions in newborns.
- Trial name
- NCT03971578
- Testing
- No Intervention Provided
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Intelligent Hearing Systems
Language Development Disorders, Down Syndrome
Strategies for Teaching Verbs
This study is designed to evaluate whether children with Down syndrome and children with typical development exhibit different levels of accuracy demonstrating novel verbs taught under three conditions: semantic cues (perform…
- Conditions
- Language Development Disorders, Down Syndrome, Child Language
- Trial name
- NCT03441685
- Testing
- Semantic cues (perform action), syntactic cues (sentence frame), or combined semantic and syntactic cues
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Short Stature
Weekly Zinc Chelate Supplementation on Children's Growth
The purpose of this study is to measure the effect of weekly zinc supplementation on schoolchildren with growth deficit or normal stature.
- Trial name
- APZinc (NCT01911260)
- Testing
- Zinc amino acid chelate
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Schizophrenia, Autism
Lurasidone Pediatric Pharmacokinetics Study
This is a Phase 1, open-label, multicenter, single and multiple ascending lurasidone dose study in subjects from 6 to 17 years old with schizophrenia spectrum, bipolar spectrum, autistic spectrum disorder, or other psychiatric…
- Trial name
- NCT01620060
- Testing
- Lurasidone
- Where
- 10 sites in United States
- Volunteers
- 105 people
- Sponsor
- Sumitomo Pharma America, Inc.
Autism, Attention Deficit Hyperactivity Disorder
A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms
This is an open-label study of the efficacy of Daytrana (methylphenidate transdermal system) for the treatment of attention and behavioral symptoms in children with Autism Spectrum Disorders.
- Trial name
- NCT00541346
- Testing
- Methylphenidate Transdermal System
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Oklahoma
SGA, Turner Syndrome
A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9
The purpose of this study is to find out if somapacitan is safe and how well somapacitan works in children either born small for gestational age or with Turner syndrome, Noonan syndrome or idiopathic short stature.
- Conditions
- SGA, Turner Syndrome, Noonan Syndrome, ISS
- Trial name
- REAL 9 (NCT05723835)
- Testing
- Somapacitan
- Where
- 18 sites in United States, Malaysia and 4 more
- Volunteers
- 47 people
- Sponsor
- Novo Nordisk A/S
Osteopetrosis
Stem Cell Transplantation for Children Affected With Osteopetrosis
Malignant infantile osteopetrosis (MIOP) is a rare fatal genetic disorder that is characterized by the bone's inability to regulate remodeling. The only curative therapy is hematopoietic stem cell transplantation.
- Trial name
- NCT00145587
- Testing
- Stem Cell Transplantation, Miltenyi Biotec CliniMACS, Systemic chemotherapy and antibodies
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- St. Jude Children's Research Hospital
Influenza
B-cell Immunity to Influenza (SLVP017)- Year 1, 2009
This is an exploratory study using a strategy that has not been previously employed to investigate the effects of age and vaccine type on specific kinds of immune responses to licensed, seasonal 2009-2010 influenza vaccines in…
- Trial name
- NCT02133781
- Testing
- Fluzone® 2009-2010 Formula, FluMist® 2009-2010 Formula
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism Spectrum Disorder, Depression
TMS for Adults With Autism and Depression
The goal of this proposal is to investigate whether a standard rTMS protocol for depression, including multiple sessions applied to left dorsolateral prefrontal cortex (DLPFC) results in reduction of depressive symptoms for adult…
- Conditions
- Autism Spectrum Disorder, Depression, Depressive Disorder, Major Depressive Disorder
- Trial name
- TAD (NCT02939560)
- Testing
- NeuroStar® TMS device (Neuronetics, Atlanta, GA)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Autism
Study of Pharmacokinetics, Safety, Efficacy, and Tolerability of Memantine in Children With Autism
The purpose of this study is to investigate the safety and efficacy of memantine extended release, as well as its extent of absorption in pediatric patients with autism.
- Trial name
- NCT00872898
- Testing
- Memantine - Extended Release (ER)
- Where
- 17 sites in United States
- Volunteers
- 124 people
- Sponsor
- Forest Laboratories