Clinical trials: Chlorhexidine
Gastroscopy
Chlorhexidine Mouthwash and Bacterial Contamination During Endoscopy
Background: Natural Orifice Transluminal Endoscopic Surgery (NOTES) is a surgical technique that has been rapidly evolving over the last five years.
- Trial name
- NCT01154530
- Testing
- Chlorhexidine
- Where
- Denmark
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Impacted Third Molar Tooth, Surgical Wound Healing
Antibacterial Effect and Soft Tissue Healing of Chlorhexidine-Coated Polyglactin 910 Sutures After Impacted Lower Third Molar Surgery
This study evaluates whether coating Polyglactin 910 sutures with chlorhexidine diacetate (CHX-DA) improves outcomes after the surgical removal of impacted mandibular (lower) third molars (wisdom teeth).
- Trial name
- NCT07794280
- Testing
- Chlorhexidine Diacetate-Coated Polyglactin 910 Suture, Uncoated Polyglactin 910 Suture
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Antisepsis
Pre-surgical Antisepsis Using an Alcoholic Solution of Chlorhexidine Digluconate and Potassium Sorbate ( Sorbectol )
The present study evaluates the effects of bactericidal load reduction after surgical hand antisepsis using the reference antiseptic product propanol- 1 60% as control versus a surgical hand antisepsis with addition of a solution…
- Trial name
- NCT04683146
- Testing
- Hand antisepsis with Propanolol- 1 60%., Hand antisepsis with a solution of alcohol, chlorhexidine digluconate and potassium sorbate.
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centro Ortopedico y Quirurgico del Pie
Root Canal Infection
Comparison of Effectiveness of Disinfectants
This is a comparative experimental study to compare the efficacy of chemical disinfection agents , sodium hypochlorite and chlorhexidine gluconate in decontaminating gutta percha cones
- Trial name
- NCT06811779
- Testing
- Sodium Hypochlorite, Chlorhexidine
- Where
- Pakistan
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Alveolar Osteitis
Evaluations of the Effects of Tranexamic Acid and Chlorhexidine Gel on Alveolar Osteitis Incidence
This intervention is the treatment of alveolar osteitis (alveolitis) with different effects, which occurs due to the formation of clot after extraction, which is one of the most common intervals after tooth extraction.98 healthy…
- Trial name
- NCT06435832
- Testing
- Absorbable Gelatin, Chlorhexidine, Tranexamic acid
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Omphalitis, Septicaemia
Efficacy of Umbilical Cord Cleansing With a Single Application of 4% Chlorhexidine for the Prevention of Newborn Infections in Uganda: a Randomized Controlled Trial
Background: Nearly all the yearly 3.3 million neonatal deaths occur in low and middle income countries. Infections, including those affecting the umbilical cord (omphalitis) are a significant factor in approximately a third of…
- Trial name
- NCT02606565
- Testing
- Intervention arm: 4% chlorhexidine
- Where
- Uganda
- Volunteers
- 4,760 people, healthy volunteers welcome
- Sponsor
- Makerere University
Oral Biofilm, Periodontitis
Methodology Antiseptic Application, Influence on Oral Biofilm.
The study has the objective to compare two different methodology of application the antiseptic on the oral biofilm will be formed during 48h in situ on a specific device.
- Conditions
- Oral Biofilm, Periodontitis, Gingivitis
- Trial name
- NCT02267239
- Testing
- essential oils, immersion, Chlorhexidine, immersion, essential oils, mouthwash
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Gingivitis
Protocol Efficacy of Mouthwashes in Experimental Gingivitis
This research was performed to find out the clinical efficacy and the anti-plaque and anti-gingivitis properties of a new oral health product (mouthwash and oral gel; StellaLife) compared to chlorhexidine.
- Trial name
- NCT07270952
- Testing
- StellaLife, Chlorhexidine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Port-Wine Stain
Pilot Study to Evaluate the Effect of Multiple Passes on Port Wine Stain Treatments With the Cutera Excel V™ Laser.
Two limitations of single pulse, laser treatment of port-wine stains (PWS) are: (i) hemorrhage and purpura which may lead to post-treatment pigmentation and (ii) the necessity for repeated treatment sessions.
- Trial name
- NCT04103164
- Testing
- Cutera excel V™ Laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Irreversible Pulpitis
Outcome Following Use of NaOCl and Chlorhexidine as Wound Lavage Agents
The goal of this clinical trial is to to compare effect of wound lavage agents NaOCl and Chlorhexidine on the outcome of partial pulpotomy in mature permanent posterior teeth with signs and symptoms indicative of irreversible…
- Trial name
- NCT06240130
- Testing
- Partial pulpotomy
- Where
- India
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Bacterial Contamination
Effectiveness of Pre-Procedural CPC and Zinc Mouthwash in Reducing Dental Aerosols
This clinical trial evaluates the effectiveness of pre-procedural mouthwashes in reducing bacterial contamination in dental aerosols generated during ultrasonic scaling.
- Trial name
- NCT07880509
- Testing
- 0.09% CPC + Zinc Lactate Mouthwash, 0.2% Chlorhexidine Mouthwash, Water
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Halitosis
Green Tea With Aloe Vera Mouthwash and Chlorohexidine Mouthwash
The Effect of Mouthwash Containing Green Tea With Aloe Vera and Chlorhexidine Mouthwash on Oral Malodour Among a Group of Egyptian Children: Randomized Clinical Trial
- Trial name
- RCT (NCT03115892)
- Testing
- Green Tea With Aloe Vera mouthwash, Chlorhexidine mouthwash
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Cairo University
HIV Infections
A Study of Chlorhexidine in the Prevention of HIV-1 Transmission From Mothers to Their Babies
The purpose of this study is to find the best strength of chlorhexidine (a solution that kills germs), for washing the mother's vagina during labor and the newborn baby, that may reduce the chance of HIV being passed from an…
- Trial name
- NCT00006075
- Testing
- Chlorhexidine gluconate
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Postoperative Flare up
Influence of Calcium Hydroxide Chlorhexidine Combination vs. Calcium Hydroxide as an Intra Canal Medicaments in Retreatment Cases
Influence of Calcium hydroxide Chlorhexidine Combination vs. Calcium Hydroxide as an Intra canal Medicamentson Postoperative flare -up following two-Visit Endodontic Retreatment cases
- Trial name
- med (NCT03209115)
- Testing
- combination of calcium hydroxide and chlorhexidine, Calcium Hydroxide
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periapical Diseases
Effect of QMix 2in1 as Final Irrigation Protocol on Periapical Healing
Aim: To compare the 12-month radiographic outcome of root canal treatment with and without the additional use of QMix 2-in-1 (Dentsply Tulsa, Maillefer, Ballaigues, Switzerland) irrigation solution.
- Trial name
- NCT04348578
- Testing
- QMix 2in1
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Teeth Staining, Numbness of the Tongue and Soft Tissue
Children Acceptance of AgNP Mouthwash Against Chlorhexidine 0.12% and Chlorhexidine .2% Mouthwashs
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine 0.12% \& Chlorhexidine 0.2%
- Conditions
- Teeth Staining, Numbness of the Tongue and Soft Tissue, Bitter Taste
- Trial name
- NCT07200063
- Testing
- nano silver mouthwash, Chlorhexidine mouthwash (0.12%), Chlorhexidine mouthwash (0.2%)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis
Comparative Evaluation of Chlorhexidine, Metronidazole and Combination Gels on Gingivitis
Patient presenting to the dental clinic with gingivitis and fulfilling the inclusion criteria will be included in the study after taking informed consent. Participants will be divided into three groups.
- Trial name
- NCT03142607
- Testing
- Metronidazole gel, Chlorhexidine Gluconate
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Antisepsis
Pre-surgical Antisepsis Using an Alcoholic Solution of Chlorhexidine Digluconate and Potassium Sorbate
The present study evaluates the effects of bactericidal load reduction after surgical hand scrub antisepsis using the reference antiseptic product propan-ol-1 60% as control versus a surgical hand scrub antisepsis with addition…
- Trial name
- sorbectol (NCT04454619)
- Testing
- Hand antisepsis with Clorhexidine and solution
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centro Ortopedico y Quirurgico del Pie
Surgical Site Infection
Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis
Primary Hypothesis: chlorhexidine gluconate alcohol skin antiseptic preparation is superior to povidone-iodine scrub and paint skin antiseptic preparation for prevention of cesarean related surgical site infection.
- Trial name
- CAPICA (NCT02202577)
- Testing
- Chlorhexidine - Isopropyl alcohol, Povidone-Iodine Scrub and Paint
- Where
- United States
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Foot Dermatoses
Chlorhexidine Scrub, ZnO Nanoparticles Socks and the Combination for Treatment of Pitted Keratolysis
This study aimed to study the efficacy of chlorhexidine scrub, zinc oxide nanoparticles (ZnO-NPs) socks and the combination of chlorhexidine scrub and ZnO-NPs socks in treatment of pitted keratolysis.
- Trial name
- PK_treatment (NCT04332796)
- Testing
- Chorhexidine scrub, ZnO-NPs socks, Combination of chorhexidine scrub and ZnO-NPs socks
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University