Clinical trials: Chlorhexidine
Dental Plaque
Efficacy of Two Chlorhexidine Solutions to Control the Initial Subgingival Biofilm Formation
The aim of the study is to compare the effect of a suspension containing chlorhexidine and alcohol and another one containing clorhexidine with no alcohol in dynamic of the subgingival biofilm formation versus a Placebo…
- Trial name
- NCT02656251
- Testing
- 0.12% Clorhexidine with alcohol, 0.12% Clorhexidine without alcohol
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Impacted Third Molar Tooth
Chlorhexidine Gel Versus Alvogyl Following Surgical Extraction of Impacted Mandibular Third Molar
Background: One of the most frequent surgical operations in dentistry is the surgical extraction of the impacted mandibular third molar, which is accompanied by a sequelae of swelling, trismus, and pain.
- Trial name
- NCT06144983
- Testing
- Alvogyl, Chlorhexidine Gluconate
- Where
- Iraq
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Nasopharangeal Cancer
Topical Chlorhexidine Spray for the Prevention of Acute Radiation Dermatitis in Patients With Nasopharyngeal Carcinoma:
This study investigated the effects of topical chlorhexidine spray on the incidence, severity, and quality of life during radiotherapy in nasopharyngeal carcinoma patients.
- Trial name
- NCT07559877
- Testing
- 2% chlorhexidine, Sterile Water as control
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Bacteremia
Efficacy of 2% Chlorhexidine Gluconate in 70% Alcohol Compare 10% Povidone Iodine in Blood Culture in Children
To evaluate the efficacy of 2% chlorhexidine gluconate in 70% alcohol compared with 10% povidone iodine in reducing blood culture contamination in pediatric patients.
- Trial name
- NCT01919593
- Testing
- 2% chlorhexidine gluconate in 70% alcohol, 10%povidone iodine
- Where
- Thailand
- Volunteers
- 1,269 people
- Sponsor
- Thammasat University
Stroke
Effectiveness, Safety and Ease of Application of Excel Cryo Cooling Collar to Rapidly Reduce Core Brain Temperature
Research has shown that lowering brain temperature may have good results in heart attack patients. Lowering brain temperature may be a promising treatment for stroke patients.
- Trial name
- CryoCollar (NCT02703675)
- Testing
- Excel Cryo Cooling Collar
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Michel Torbey
Plaque Induced Gingivitis
Comparative Efficacy of Oil Pulling and Chlorhexidine on Plaque Induced Gingivitis
This randomized clinical trial aims to compare the efficacy of chlorhexidine and coconut oil in plaque-induced gingivitis patients.
- Trial name
- chx oilpulling (NCT07769112)
- Testing
- Chlorhexidine mouthwash (0.12%), coconut oil pulling
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Liaquat College of Medicine and Dentistry
Nosocomial Bacteremia, Nosocomial Fungemia
The Impact of Chlorhexidine-Based Bathing on Nosocomial Infections
The purpose of this study was to determine if the use of daily chlorhexidine bathing would decrease the incidence of MRSA and VRE colonization and healthcare associated Bloodstream Infections (BSI) among Intensive Care Unit (ICU)…
- Conditions
- Nosocomial Bacteremia, Nosocomial Fungemia, MRSA Colonization, MRSA Infection
- Trial name
- NCT00448942
- Testing
- Daily bathing with Chlorhexidine based product
- Where
- 4 sites in United States
- Volunteers
- 5,300 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Periodontal Pocket
Comparative Evaluation of Bromelain-Quercetin Gel With Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing In Stage I /II and Grade B Periodontitis - Randomized Control Clinical Trail
Comparative Evaluation of Bromelain-Quercetin Gel With Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing In Stage I /II and Grade B Periodontitis - Randomized Control Clinical Trail
- Trial name
- NCT06775392
- Testing
- bromelain-quercetin gel, chlorhexidine gel, SRP
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Chronic Gingivitis, Plaque Induced
Comparative Evaluation of Guava Leaf Extract and Chlorhexidine Mouthwash in Patients With Chronic Gingivitis
The goal of this clinical trial is to compare the effectiveness of 0.15% guava (Psidium guajava) leaf extract mouth rinse with 0.2% Chlorhexidine (CHX) mouth rinse in reducing plaque accumulation, gingival inflammation, and oral…
- Trial name
- NCT07059572
- Testing
- Group A- 0.15% Guava leaf extract mouthwash group, Group B- 0.2% Chlorhexidine mouthwash
- Where
- Bangladesh
- Volunteers
- 160 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Periodontitis
Clinical Efficacy of Mouthrinses Based on Chlorhexidine 0.12% and CITROX®
The goal of the following clinical trial is to compare the efficacy of a product based on chlorhexidine 0.12% and CITROX and the same product without CITROX in the healing phenomena that occur after non-surgical periodontal…
- Trial name
- NCT06341439
- Testing
- Mouthwash with chlorhexidine 0,12% and CITROX, Mouthwash with chlorhexidine 0,12%
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of L'Aquila
Staphylococcus Aureus, Community-acquired Infections
Chlorhexidine Impregnated Cloths to Prevent Skin and Soft Tissue Infections in Marine Officer Candidates
Outbreaks of skin and soft tissue infections (SSTI) related to community associated Methicillin-resistant Staphylococcus aureus (MRSA) have become increasingly common in military training units.
- Conditions
- Staphylococcus Aureus, Community-acquired Infections, Staphylococcal Skin Infections
- Trial name
- NCT00475930
- Testing
- 2% chlorhexidine gluconate (CHG) impregnated cloths
- Where
- United States
- Volunteers
- 1,563 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Colorectal Cancer, Surgical Site Infection
Chlorhexidine Gluconate Versus Saline for Flushing the Surgical Area During Colorectal Cancer Surgery
The aim of this study was to compare the effectiveness of chlorhexidine versus saline in flushing the surgical area during colorectal cancer surgery.
- Conditions
- Colorectal Cancer, Surgical Site Infection, Chlorhexidine, Complications
- Trial name
- NCT06869096
- Testing
- Intraoperative area irrigation
- Where
- China
- Volunteers
- 532 people
- Sponsor
- Nanchong Central Hospital
Wound Healing, Alveolitis of Jaw
Effect of Curcumin Topical Spray on Wound Healing After Tooth Extraction
This randomized, single-blind, controlled clinical trial aims to evaluate the effects of a topical curcumin spray on post-extraction wound healing and postoperative symptoms in adults undergoing first molar extraction.
- Conditions
- Wound Healing, Alveolitis of Jaw, Tooth Extraction, Curcumin
- Trial name
- NCT07874789
- Testing
- Curcumin Topical Spray, Chlorhexidine Topical Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Peritoneal Dialysis Catheter Exit Site Infection
Chlorhexidine Disk for Prevention of Exit-site Infection in Peritoneal Dialysis Patients
The purpose of the study is to evaluate the efficacy and safety of chlorhexidine-impregnated disk in preventing catheter exit-site infection in peritoneal dialysis patients
- Trial name
- NCT03406520
- Testing
- Chlorhexidine-impregnated disk
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Antisepsis
Pre-surgical Antisepsis Using an Alcoholic Solution of Chlorhexidine Digluconate and Potassium Sorbate ( Sorbectol )
The present study evaluates the effects of bactericidal load reduction after surgical hand antisepsis using the reference antiseptic product propanol- 1 60% as control versus a surgical hand antisepsis with addition of a solution…
- Trial name
- NCT04683146
- Testing
- Hand antisepsis with Propanolol- 1 60%., Hand antisepsis with a solution of alcohol, chlorhexidine digluconate and potassium sorbate.
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centro Ortopedico y Quirurgico del Pie
Dental Caries
Properties of Glass Ionomer Cements Associated With Chlorhexidine or Doxycycline
This study assessed the clinical performance of a resin-modified glass ionomer cement containing different concentrations of chlorhexidine digluconate and doxycycline hyclate.
- Trial name
- NCT02168374
- Testing
- Indirect pulp treatment
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Aline R F de Castilho
Neonatal Mortality, Cord Care
Chlorhexidine Cordcare for Reduction in Neonatal Mortality and Omphalitis
In a community-based controlled trial among children to evaluate if use of 4% Chlorhexidine cleansing solution on umbilical cord of infants in first 10 days of life results in Reduction in neonatal mortality (deaths in first 28…
- Conditions
- Neonatal Mortality, Cord Care, Omphalitis
- Trial name
- CHX-Pemba (NCT01528852)
- Testing
- Chlorhexidine 4%, Control cord cleaning solution
- Where
- Tanzania
- Volunteers
- 36,911 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Plaque Induced Gingival Disease
Role of Herbal Based Mouthwashes in Plaque Control
Herbal medicine has been used for thousands of years. Traditional herbal medicine is used by an estimated 80% of the world's population for primary health care.
- Trial name
- mouthwash (NCT06711263)
- Testing
- Mouthwash Product
- Volunteers
- 80 people
- Sponsor
- Ajman University
Bacterial Vaginosis (BV)
Chlorhexidine and/or Metronidazole Plus FB301 Pre-treatment Trial
The goal of this study is to evaluate how treatment with FB301 affects the balance of vaginal bacteria in women (aged 18-45) with bacterial vaginosis after pre-treatment with either a vaginal antiseptic wash (chlorhexidine), an…
- Trial name
- NCT07481955
- Testing
- FB 301, Chlorhexidine 0.5%, metronidazole 500 mg
- Where
- 2 sites in Germany
- Volunteers
- 120 people
- Sponsor
- Freya Biosciences ApS
Periodontal Diseases
Treatment of Periodontal Disease With Two Different Bioactive Gels for Home Oral Care
This study is an open-label split-mouth study in which periodontal patients will be treated in order to obtain periodontal health.
- Trial name
- NCT04781478
- Testing
- Application of Biorepair Gel, Irrigation of Chlorhexidine 1.00% gel
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pavia