Clinical trials: Chloride Disorder
Infectious Diseases
Chlorhexidine Against Sodium Hypochlorite as Skin Antiseptics
The physicians have few options for skin antisepsis. Alternatives for common use antiseptics are costly or ineffective. In order to have more options, this study is needed.
- Trial name
- NCT01321125
- Testing
- Bacterial culture of the prepared skin's areas, Preparing skin's areas to be tested, Antiseptic substantivity
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Guanajuato
Malnutrition, Diarrhea
WASH Benefits Kenya
The purpose of this study is to measure the independent and combined effects of interventions that improve sanitation, water quality, handwashing, and nutrition on child health and development in the first years of life.
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- WASHB-Kenya (NCT01704105)
- Testing
- Water Quality, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 8,246 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Dentin Sensitivity
The Strontium Chloride Associated With Photobiomodulation in the Control of Post-bleaching Sensitivity
This study investigated the effects of the association of strontium chloride with photobiomodulation on the dental bleaching process, testing the hypothesis that they may control dental sensitivity post-bleaching teeth.
- Trial name
- NCT04356911
- Testing
- FBM, ESTRÔNCIO, FBM+ESTRÔNCIO
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Allergic Conjunctivitis
Comparison of CL Wear Between Two Allergy Drops
Comparison of two allergy drops for enhancing comfort and performance of contact lens wear
- Trial name
- NCT00489398
- Testing
- epinastine HCL and olopatadine HCL
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hom, Milton M., OD, FAAO
Dehydration
IV NaCl (Sodium Chloride) 0.9% Vs (Versus) IV NaCl 0.9% + 5% Dextrose in Pediatric ER for Dehydration
Dehydration and refusal to eat and drink are common complaints in the Pediatric ED (Emergency Department). Most of these children have had an unsuccessful trial of oral rehydration in their community service, therefore are…
- Trial name
- NCT02054585
- Testing
- NaCl 0.9%, NaCl 0.9 +5% dextrose
- Where
- Israel
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Dysphagia
Effects of 3% Sodium Chloride on Post-operative Dysphagia Following Anterior Cervical Spine Surgery
Post-operative dysphagia is a significant issue following anterior cervical spine surgery. The investigators are studying the effects of perioperative 3% sodium chloride, given over a period of 24 hours, on post-operative…
- Trial name
- NCT03677310
- Testing
- 3% Sodium Chloride, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Dental Plaque, Side Effects
Clinical Effects of Two New Chlorhexidine Digluconate Formulations: 0.12% and 0.03%.
In the current study we tested the hypothesis that new 0.05% Cetylpyridinium chloride (CPC) mouthrinse formulations containing 0.12% or 0.03% chlorhexidine digluconate (CHX): 1) yield similar or better clinical results regarding…
- Trial name
- NCT02194023
- Testing
- 0.12%NF, 0.03%NF, PAT
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Gingivitis, Plaque
Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.
Qualified subjects will be enrolled and randomized to one of the two study groups based on their initial Plaque and Gingivitis scores. Subjects will be instructed to use the products according to the instructions provided.
- Trial name
- NCT06244303
- Testing
- manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F), manual toothbrush + Colgate dental cream
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Ocular Surface Disease, Dry Eye Syndromes
A Comparative Study Between Preservative With Benzalkonium Chloride vs Preservative Free Eye Drops on the Ocular Surface
study the effect of different concentrations of benzalkonium chloride on the ocular surface of non-dry-eyed patients post cataract surgery.
- Trial name
- NCT06404541
- Testing
- Dexamethasone, tobramycin, netilimicin
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Heterozygous Carriers of Gitelman Syndrome
Clinical Significance of Heterozygosity for Mutations of the SLC12A3 Gene Coding for the Thiazide Sensitive Na-Cl Cotransporter
Gitelman syndrome is a salt wasting tubulopathy caused by mutations in the SLC12A3 gene coding for the thiazide sensitive sodium chloride cotransporter.
- Trial name
- HEPHYGI (NCT02035046)
- Testing
- Samplings of blood, Sampling of urine, Measure of the blood pressure
- Where
- 5 sites in France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Malnutrition, Diarrhea
WASH Benefits Bangladesh
Brief Summary: The purpose of this study is to measure the independent and combined effects of interventions that improve water quality, sanitation, hand washing, and nutrition on child growth and development in the first years…
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- NCT01590095
- Testing
- Water quality, Sanitation, Hand washing
- Where
- Bangladesh
- Volunteers
- 5,040 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Vertigo
Evaluation of Aminobutyric Acid, Glutamic Acid, Calcium, Thiamine, Pyridoxine and Cyanocobalamin as Therapy for Vertigo
The goal of this clinical trial is to assess the efficacy and safety of a combination of aminobutyric acid, glutamic acid, calcium, thiamine, pyridoxine and cyanocobalamin as adjuvant therapy for vertigo comparatively to ginger…
- Trial name
- NCT05221892
- Testing
- Gamma-aminobutyric acid tartarate, glutamic acid, dibasic calcium phosphate, thiamine nitrate, pyridoxine chloride and cyanocobalamin, Ginger
- Where
- Brazil
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Fundação Educacional Serra dos Órgãos
Acidosis, Renal Tubular, Nephrolithiasis
Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis
Purpose 1. To compare the performance of the two currently employed urinary acidifications tests in stone formers, the furosemide/fludrocortisone and ammonium chloride loading test. 2.
- Conditions
- Acidosis, Renal Tubular, Nephrolithiasis, Vacuolar Proton-Translocating ATPases
- Trial name
- NCT01690039
- Testing
- Furosemide-Fludrocortisone-Test (test for urinary acidification)
- Where
- Switzerland
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Glaucoma; Ocular Disorders (I.E. Caused by Ocular Disorders)
Comparison of Different Drugs on Ocular Surface Disease in Glaucoma Patients: a Prospective Randomised Study
Participants were randomised to receive benzalkonium chloride-containing latanoprost (Xalatan) or preservative-free bimatoprost (Lumigan).
- Trial name
- NCT04896125
- Testing
- Lumigan PF; Xalatan
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Respiratory Infection
Test of a Preventive Effect of a Deodorant Device Against Respiratory Infections
This study is to test whether a chlorine dioxide gas-generating device, which releases a low concentration gas of chlorine dioxide in a sustained manner, can protect against respiratory infections in elderly individuals living in…
- Trial name
- Cleverin (NCT00969800)
- Testing
- Cleverin Gel, Inactive Cleverin Gel
- Where
- Japan
- Volunteers
- 1,469 people, healthy volunteers welcome
- Sponsor
- Taiko Pharmaceutical Co., Ltd.
Dental Plaque, Gingivitis
Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)
The objective of this clinical research study is to assess the efficacy of a commercially available triclosan/copolymer toothpaste compared to a commercially available oral hygiene multi-component regimen encompassing the use of…
- Trial name
- NCT02366689
- Testing
- Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Ocular Dryness, Ocular Irritation
Dry Eye and Irritation Comparison of Latanoprost With the Preservative Versus Travoprost Without Preservative
Although Benzalkonium chloride (BAC) has been used as a preservative for many years, many studies have demonstrated that prolonged use of topical ocular medications preserved with BAC may exacerbate sequelae associated with…
- Conditions
- Ocular Dryness, Ocular Irritation, Open-Angle Glaucoma, Ocular Hypertension
- Trial name
- NCT00803387
- Testing
- Travaprost without BAC (Travatan Z)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- United States Air Force
Hypertension
Urine Chloride/Creatinine Ratio for Estimation of Urine Sodium
We plan to assess the accuracy of a new means of estimating urine sodium excretion. We will compare the chloride to creatinine ratio obtained by titrator sticks with urine sodium measured by a standard laboratory.
- Trial name
- NCT00324883
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Th17 Helper Immune Cells, Autoimmunity
Salt and TH-17 in Healthy Human Subjects
The overall goal of this study is to evaluate the association between sodium and TH17 cells in human subjects. The subjects will have levels of TH-17 and various hormones measured on low salt diet, low salt diet with intravenous…
- Conditions
- Th17 Helper Immune Cells, Autoimmunity, Salt Intake, Sodium Chloride
- Trial name
- NCT02261688
- Testing
- Low salt diet, Low salt diet + IV normal saline, Liberal salt diet
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Neurogenic Bladder, Spina Bifida
Comparing Urinary Tract Infections in Children With Spina Bifida Using Two Types of Catheters for Catheterization
The primary aim of this study was to determine if using the SpeediCath hydrophilic catheter would reduce the incidence of symptomatic urinary tract infections (UTI)in children with spina bifida who perform clean intermittent…
- Trial name
- NCT01263392
- Testing
- Intermittent catheterization
- Where
- 4 sites in Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Alberta