Clinical trials: Chronic Orofacial Pain
Burning Mouth Syndrome
Opiorphin Levels in Fluids of Burning Mouth Syndrome Patients (OPIODYN)
If epidemiological studies indicate relatively low prevalence reported in the general population, idiopathic burning mouth syndrome (BMS) is a common condition among certain groups of the population: 30% of menopausal women…
- Trial name
- OPIODYN (NCT02686359)
- Testing
- sample
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
TMD/Orofacial Pain, Fibromyalgia (FM)
Diagnostic and Prognostic Salivary Biomarkers in Chronic Muscle Pain
A large proportion of the adult population worldwide currently lives with chronic muscle pain, with more than half of those affected experiencing pain localized to the face and jaw.
- Trial name
- NCT06994156
- Where
- Sweden
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Temporomandibular Disorders (TMDs)
Diagnostic Study Accuracy of Jaw Motion Analyzer(JMA) Versus Research Diagnostic Criteria(RDC/TMD) and Magnetic Resonance Imaging(MRI) for Temporomandibular Disorders Among Patients With Chronic Orofacial Pain.
The goal of this diagnostic accuracy study is to determine the diagnostic accuracy of jaw motion analyzer(JMA) in terms of sensitivity and specificity with target cut of points used by valid reference standards which will be the…
- Trial name
- NCT07486609
- Testing
- The Jaw Motion Analyzer (JMA, Zebris, Germany) as the index test, Research Diagnostic Criteria for Temporomandibular Disoders, Magnetic Resonance Imaging
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myalgia, Muscle Pain
Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin
The main aim of the presented project will be to examine the concentration of selected receptors (CB1, CB2, TRPV-1) showing affinity for binding to cannabidol (CBD) and cannabinol (CBN) in blood samples collected from people with…
- Conditions
- Myalgia, Muscle Pain, Orofacial Pain, Headache, Tension
- Trial name
- NCT06405646
- Testing
- Blood CB1, CB2, TRPV-1 concentration measurement
- Where
- Poland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Chronic Masticatory Myofascial Pain
Masticatory Muscle Activity Using a 24-Hour Wearable Device
Patients with chronic masticatory myofascial pain (MFP) often report that stress and parafunctional oral habits aggravate their pain, consistent with the widespread belief that stress and parafunctional habits lead to…
- Trial name
- NCT07861906
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Chronic Pain
Emotional Intelligence and Chronic Orofacial Pain
Chronic pain, lasting more than three months, is a widespread health issue that negatively impacts daily life, leading to significant emotional distress and functional impairment.
- Trial name
- IEDOF (NCT07280338)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Temporomandibular Joint Disorders
Acute Effects of Alcohol Use on Chronic Orofacial Pain
Self-medication of pain with alcohol is a common, yet risky, behavior among individuals with chronic orofacial pain. Chronic pain status may affect the degree to which alcohol use relieves pain, but the independent contributions…
- Trial name
- NCT04019093
- Testing
- Ethanol
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Florida
Toothache, Temporomandibular Joint Disorders
Multimodal Assessment of Sensory Processing and Brain Features in Patients With Chronic Orofacial Pain
This proposal will investigate pain modulatory mechanisms and brain functional and structural characteristics using multiple MRI modalities in persistent dentoalveolar pain disorder (PDAP) patients with and without…
- Trial name
- NCT02630771
- Testing
- Pressure pain threshold
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Orofacial Pain
Effects of Transcranial Direct Current Stimulation (tDCS) on Patients With Chronic Orofacial Pain
Patients affected by chronic orofacial pain represent an emergent medical problem due to the lack of knowledge on the cause, pathophysiology and psychology of many of these conditions, that belongs to a multifactorial origin.
- Trial name
- NCT01883245
- Testing
- real tDCS
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara