Clinical trials: Chronic Spinal Pain
Ilioinguinal Nerve Block
The Effects of Ilioinguinal Nerve Block on Chronic Pain in Patients in Inguinal Hernia With Spinal Anesthesia
Regional anesthesia is a popular anesthetic method in patients who will undergo an inguinal hernia operation. Researchers known that pain in the operating area is a complaint that impairs the quality of life for patients in the…
- Trial name
- NCT04295629
- Testing
- Research on the effects of Ilioinguinal Nerve Block on Chronic Pain in Patients who undergo Inguinal Hernia with Spinal Anesthesia, Ilioinguinal nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Low Back Pain
Non-Specific Chronic Back Pain; Insight From Spatial Aspects of Lumbar Spinal Muscle Activation
There is evidence for altered muscle activity patterns in individuals with non-specific chronic back pain (NSCBP). It is unknown why these alterations in activation pattern occur and how they may be linked to pain experience and…
- Trial name
- NCT01214213
- Where
- Norway
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Chronic Pain, Spinal Cord Injury
Effects of Transcranial Direct Current Stimulation (tDCS) and Visual Illusion on Chronic Pain Due to Spinal Cord Injury
The purpose of this study is to investigate the effects of Transcranial Direct Current Stimulation (tDCS) combined with watching a visual illusion on chronic pain due to spinal cord injury.
- Trial name
- NCT01404065
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Back Pain, Back Disorder
Clinical Trial of Dvectis Pads in Comparison to no Pad Use in Patients With Chronic Lumbar Spine Pain
1. Introduction 1.1 Description of the Trial The trial was a monocentric, open, randomized, 3-arm clinical trial that took place at the Department of Orthopaedics of the Karviná Miners' Hospital (Karvinská hornická nemocnice…
- Conditions
- Back Pain, Back Disorder, Disease Lumbar Spine
- Trial name
- NCT03947580
- Testing
- Use of the Dvectis Single pad, Use of the Dvectis Double pad, Use of no pad
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- DD-Hippero s.r.o.
Chronic Neck Pain
The Effects of Spinal Manipulation on Performance on Neck Pain Patients During a Fitts' Task
The objective of this study is to quantify motor performance, this study will use an eye movement Fitts' task to examine the effects of cervical spine manipulation on participants with chronic neck pain and the subsequent changes…
- Trial name
- NCT04347551
- Testing
- High velocity/low amplitude cervical spine manipulation
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Spinal Stenosis Lumbar, Surgical Site Infection
Efficacy of ActiveMatrix on Spinal SSI Rate
This clinical trial seeks to provide high level of evidence on the efficacy of ActiveMatrix primarily on spinal surgical site infection rate.
- Conditions
- Spinal Stenosis Lumbar, Surgical Site Infection, Back Pain Lower Back Chronic
- Trial name
- NCT05297513
- Testing
- ActiveMatrix
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Pain, Healthy
Predicting Central Pain Among People With a Spinal Cord Injury by Evaluating Mechanisms Regulating Pain and Efficacy Testing of the TENS Apparatus
People with a Spinal Cord Injury can develop chronic pain within months of the injury. Up to 80% of the patients will develop chronic pain called "central pain" and describe the pain as: burning, stabbing, or "like electricity."…
- Trial name
- NCT01726881
- Testing
- Thermal stimulation, Mechanical stimulation, Transcutaneous Electrical Nerve Stimulator (TENS)
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Type 2 Diabetes, Neuropathy, Painful
Methylglyoxal Evaluation in Humans
The investigators will test the hypothesis that patients with low back pain associated with lumbar disc aberrancy will have elevated MGO-protein levels circulating in the blood that are comparable to patients with painful…
- Conditions
- Type 2 Diabetes, Neuropathy, Painful, Chronic Low-back Pain, Lumbar Disc Herniation
- Trial name
- MEH (NCT05350553)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Degenerative Disc Disease
Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain
The objective of this study is to evaluate the safety and efficacy of viable allograft transplantation for the treatment of patients with symptomatic disc degeneration and tissue loss.
- Trial name
- VAST (NCT03709901)
- Testing
- Active Allograft
- Where
- 13 sites in United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- VIVEX Biologics, Inc.
Chronic Pain
Optimal Stimulation Programming for Spinal Peripheral Neuromodulation
To determine the best parameters with various leads to cover back and leg pain and provide best pain relief
- Trial name
- NCT02346383
- Testing
- preset program
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Carolinas Center for Advanced Management of Pain
Low Back Pain, Neuromuscular Subluxation of Joint
Effects of Dynamic Stabilizatıon Exercises and HVLA Manipulatıon in Low Back Paın
Our aim is to contribute to the literature by comparatively examining the effects of DNS exercises and chiropractic HVLA manipulation on pain, pain-related functional impairment (disability), physical competence level, dynamic…
- Trial name
- DNSHVLA (NCT06277700)
- Testing
- Chiropractic Manipulation (HVLA - high velocity low amplitude), Dynamic Neuromuscular Stabilization
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Pain
The Effect of Pregabalin and Dexamethasone on Acute and Chronic Pain After Lumbar Spinal Surgery
Multimodal analgesia may be important for optimal postoperative pain treatment and facilitation of early mobilization and recovery.
- Trial name
- NCT01168531
- Testing
- Pregabalin, dexamethasone
- Where
- South Korea
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Chronic Pain, Fibromyalgia
Chronic Pain, Couples, & Physical Activity
Chronic pain affects more than 50 million adults in the United States and is estimated to cost the nation more than $560 billion dollars each year.
- Conditions
- Chronic Pain, Fibromyalgia, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT04077164
- Testing
- No intervention, observational only.
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Illinois Institute of Technology
Low Back Pain, Spinal Manipulation
Comparison of The Effectiveness of Spinal Manipulation and Yoga in Chronic Low Back Pain
The aim of our study was to compare the effectiveness of chiropractic manipulation and yoga-based exercise techniques on pain, functionality, depression and anxiety in patients with long-term low back pain.
- Conditions
- Low Back Pain, Spinal Manipulation, Yoga
- Trial name
- CTESMYCLBP (NCT06291168)
- Testing
- Chiropractic Manipulation (HVLA - High Velocity Low Amplitude), Yoga-Based Exercise Program, Conventional Exercises
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Low Back Pain, Disc Disease
Fibrin for Chronic Multi-level Discogenic Low Back Pain
Intra-annular injections of non-autologous fibrin for moderate to severe chronic low back pain (LBP).
- Conditions
- Low Back Pain, Disc Disease, Disc Degeneration, Radiculopathy
- Trial name
- NCT04621799
- Testing
- Fibrin sealant
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Pauza, Kevin, MD
Neck Pain
The Investigation of Thoracic Spinal Curvature and Mobility in Subjects With and Without Neck Pain: Cut-off Points
The purpose of this study is to investigate the sagittal thoracic spinal curvature and mobility in subjects with and without chronic neck pain, cut-off points and pain relationship
- Trial name
- NCT02424058
- Testing
- Spinal Mouse® measurement, Neck pain intensity measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk Training and Research Hospital
Chronic Low-Back Pain, Refractory Pain
Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)
The objective of this study is to evaluate the efficacy of BurstDR dorsal column stimulation, compared with conventional medical management, in improving pain and back-related physical function in subjects suffering with chronic…
- Conditions
- Chronic Low-Back Pain, Refractory Pain, Neuropathic Pain
- Trial name
- NCT04479787
- Testing
- Spinal Cord Stimulation, Conventional Medical Management
- Where
- 30 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Chronic Pain, Spasticity as Sequela of Stroke
Closed Loop Spinal Cord Stimulation for Neuromodulation of Upper Motor Neuron Lesion Spasticity
Spasticity is characterized by increased muscle tension and is a classic consequence of upper motor neuron (UMN) damage in the central nervous system, such as from stroke or trauma.
- Conditions
- Chronic Pain, Spasticity as Sequela of Stroke, Upper Motor Neuron Lesion
- Trial name
- CLONUS (NCT06384170)
- Testing
- Spinal Cord Stimulation- Closed loop
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Spinal Cord Injury, Hyperalgesia, Secondary
MR Spectroscopy as a Diagnostic and Outcome Measure in Pain and SCI
The goal of this study is to compare the changes that occur in sensation and chemical properties of the brain following SCI between individuals that experience chronic pain and those that do not, and between those with SCI and…
- Conditions
- Spinal Cord Injury, Hyperalgesia, Secondary, Hyperalgesic Sensations
- Trial name
- MRS (NCT00561782)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Low Back Pain, Recurrent, Degenerative Disc Disease
GDS Muscle and Articulation Chain Treatment for Chronic LBP and Spinal Stenosis
Our purpose is to conduct a pilot study to evaluate GDS muscle and articulation chain treatment for inoperable spine patients with degenerative changes in the lumbar spine, compared to "standard treatment" (any other chosen…
- Trial name
- GDS (NCT04436003)
- Testing
- Muscle and articulation chains GDS method
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hospital of Vestfold